المؤلفون: Yongzheng Zhang, Stephen M. Manzo, Derek A. Beauchamp, Sergio Cesco-Cancia, Xun Li, Ahmed F. Abdel-Magid, Fuh-Rong Tsay, Scott A. Ballentine, Caterina Ferraro, Kenneth M. Wells, Christopher A. Teleha, Hua Marlon Zhong, Scott Youells, Steven J. Mehrman, Ronald K. Russell, Lorraine Scott, Jan M. Spink, Craig Diamond

المصدر: Organic Process Research & Development. 19:1774-1783

مصطلحات موضوعية: chemistry.chemical_compound, Transient receptor potential channel, Trifluoromethyl, Suzuki reaction, Process development, Chemistry, Stereochemistry, Yield (chemistry), Organic Chemistry, TRPV1, Antagonist, Imidazole, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8d85dfd2095f7bcb55164604dce960af
https://doi.org/10.1021/acs.oprd.5b00271

المؤلفون: Ronald K. Russell, Yongzheng Zhang, Marc Verbeek, Michael Reuman, Zhihua Sui, Hilde Vanbaelen, Christopher A. Teleha, Shawn Branum, James C. Lanter, Fawzy Nagy E, Fu-An Kang, Luc Van Der Steen, Michael Kolpak, Michael P. Winters, Derek A. Beauchamp, Gregory C. Leo

المصدر: Organic Process Research & Development. 18:1630-1640

مصطلحات موضوعية: Chemokine Receptor Antagonist, chemistry.chemical_compound, Chemokine receptor, Chemistry, Stereochemistry, Furan, Reagent, Organic Chemistry, Antagonist, Physical and Theoretical Chemistry, Alkylation, Reductive amination, Coupling reaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6e2ea61a6b3e2fe6f4999868e3c1c57
https://doi.org/10.1021/op500266w

المؤلفون: Shawn Branum, Fawzy Nagy E, Christopher A. Teleha, Luc Van Der Steen, Mark J. Wall, Derek A. Beauchamp, Michael Reuman, Marc Verbeek, Michael Kolpak, Zhihua Sui, Chaozhong Cai, Gregory C. Leo, Ronald K. Russell, Yongzheng Zhang, Fu-An Kang, Hilde Vanbaelen

المصدر: Organic Process Research & Development. 18:1622-1629

مصطلحات موضوعية: chemistry.chemical_classification, Chemokine Receptor Antagonist, Chemokine receptor, chemistry, Bicyclic molecule, Stereochemistry, Carboxylic acid, Organic Chemistry, Diastereomer, Physical and Theoretical Chemistry, Radical cyclization, Reductive amination, Coupling reaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::30ed40727f516d73f0e1e4e53e8301d9
https://doi.org/10.1021/op500265z

المؤلفون: Derek A. Beauchamp, Jan M. Spink, Scott A. Ballentine, Christopher A. Teleha, Ronald K. Russell, Kenneth M. Wells, Shawn Branum, Mark R. Player, Xun Li, William V. Murray, Raymond J. Patch, Hui Huang

المصدر: Organic Process Research & Development. 18:321-330

مصطلحات موضوعية: chemistry.chemical_compound, Trifluoromethyl, chemistry, Stereochemistry, Organic Chemistry, Diastereomer, Regioselectivity, Epoxide, Amine gas treating, Knoevenagel condensation, Physical and Theoretical Chemistry, Reductive amination, Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::88828a3d66c963401b5e0df09d341aef
https://doi.org/10.1021/op400325r

المؤلفون: Kenneth M. Wells, Lian Huang, Bao-Ping Zhao, Ronald K. Russell, Scott Youells, Derek A. Beauchamp, Zhiyong Hu, Steven J. Mehrman, Adam Fermier, Gilles Bignan, Xun Li, Micheal Gaul, James V. Weber, Mark J. Macielag, Guozhang Xu, Wenju Wu

المصدر: Crystal Growth & Design. 13:4635-4641

مصطلحات موضوعية: Computer science, Nanotechnology, General Chemistry, Condensed Matter Physics, Small molecule, law.invention, Workflow, Preclinical testing, law, Scientific method, Scalability, General Materials Science, Physical stability, Crystallization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::74fbfe37cd234cba19d9e5b76e78e481
https://doi.org/10.1021/cg401147b

المؤلفون: Zhihua Sui, Derek A. Beauchamp, Christopher A. Teleha, Ronald K. Russell, Chaozhong Cai, Fu-An Kang

المصدر: Tetrahedron: Asymmetry. 24:651-656

مصطلحات موضوعية: Inorganic Chemistry, Steric effects, chemistry.chemical_compound, Bicyclic molecule, Chemistry, Stereochemistry, Organic Chemistry, Cyclopentene, Physical and Theoretical Chemistry, Ring (chemistry), Catalysis, Cycloaddition

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a63aa46f9ea716d2c141f8aca41fa9c1
https://doi.org/10.1016/j.tetasy.2013.04.014

المؤلفون: Kenneth M. Wells, Xun Li, Sandra Damon, Shawn Branum, William V. Murray, David Palmer, Ronald K. Russell, Scott Youells, Derek A. Beauchamp, Stephen M. Stefanick

المصدر: Organic Process Research & Development. 16:1727-1732

مصطلحات موضوعية: chemistry.chemical_classification, Acylation, Chemistry, SGLT Inhibitors, Stereochemistry, Organic Chemistry, Glucose transporter, Glycoside, Physical and Theoretical Chemistry, Clinical evaluation, Sodium dependent, Coupling reaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::540ba2843e6df08b5ab82fc05020c3ea
https://doi.org/10.1021/op3001355

المؤلفون: Devraj Chakravarty, Sandra Damon, Kenneth J. Rhodes, Mark Ault, Robert H. Scannevin, Lori Westover, Xun Li, Vernon C. Alford, Aihua Wang, Heng-Keang Lim, Lisa Lampron, Jeffrey Crooke, Scott Youells, Paul F. Jackson, Ronald K. Russell, J. Kent Barbay, Mark T. Powell, Stefanie Rassnick, Derek A. Beauchamp, Shawn Branum, Kenneth M. Wells, Kristi A. Leonard, Nathaniel H. Wallace, Karen Carroll, Brian C. Shook

المصدر: Journal of Medicinal Chemistry. 55:1402-1417

مصطلحات موضوعية: Parkinson's disease, Chemistry, Catalepsy, Pharmacology, medicine.disease, Adenosine, Lesion, Adenosine A1 receptor, Oral administration, Drug Discovery, medicine, Molecular Medicine, Structure–activity relationship, medicine.symptom, Receptor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ee5bfe2808914e06827f196af1afcb35
https://doi.org/10.1021/jm201640m

المؤلفون: Brian C. Shook, Kenneth C. Rupert, Stefanie Rassnick, Hall Daniel A, Scott Davis, Sandra Damon, Reyes Mayra B, Lori Westover, Melville C. Osborne, Scott Youells, Yuting Tang, Ronald K. Russell, Keith T. Demarest, Xun Li, Paul F. Jackson, Shawn Branum, Devraj Chakravarty, Derek A. Beauchamp, Kristin Hansen, Kenneth J. Rhodes, David C. Palmer, James L. Bullington, Geoffrey R. Heintzelman, Kenneth M. Wells, Jamie Boulet

المصدر: Journal of Medicinal Chemistry. 53:8104-8115

مصطلحات موضوعية: Male, Parkinson's disease, Receptor, Adenosine A2A, Administration, Oral, Adenosine A1 Receptor Antagonists, Pharmacology, Catalepsy, Antiparkinson Agents, Rats, Sprague-Dawley, Mice, Adenosine A1 receptor, In vivo, Drug Discovery, medicine, Animals, Receptor, Mice, Inbred BALB C, Chemistry, Antagonist, Callithrix, Parkinson Disease, medicine.disease, Adenosine, In vitro, Adenosine A2 Receptor Antagonists, Rats, Disease Models, Animal, Macaca fascicularis, Pyrimidines, Indenes, Molecular Medicine, Female, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a3abc6b1bb2388ce859a84328d2aeb
https://doi.org/10.1021/jm100971t

المؤلفون: Sandra Damon, Lori Westover, Kenneth C. Rupert, Ronald K. Russell, Xun Li, Devraj Chakravarty, Paul F. Jackson, Brian Magliaro, Yuting Tang, Geoffrey R. Heintzelman, Kenneth M. Wells, Stefanie Rassnick, Shawn Branum, Mel Osbourne, Karen Carroll, Kenneth J. Rhodes, James L. Bullington, Robert H. Scannevin, Keith T. Demarest, Lisa Lampron, Brian C. Shook, Scott Youells, Kristen Hansen, Hall Daniel A

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:2864-2867

مصطلحات موضوعية: Receptor, Adenosine A2A, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Adenosine A1 Receptor Antagonists, Catalepsy, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Dopamine, Drug Discovery, medicine, Animals, Structure–activity relationship, Amines, Methylene, Receptor, Molecular Biology, Neurotransmitter Agents, Receptor, Adenosine A1, Organic Chemistry, medicine.disease, In vitro, Adenosine A2 Receptor Antagonists, Disease Models, Animal, Pyrimidines, Adenosine a, chemistry, Molecular Medicine, Amine gas treating, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81d5b2a5b35b6c6aec43edf95869ec0
https://doi.org/10.1016/j.bmcl.2010.03.042

المؤلفون: Scott Youells, Robert H. Scannevin, Mark T. Powell, Sandra Damon, Ronald K. Russell, Paul F. Jackson, Lori Westover, Lisa Lampron, Jeffrey Crooke, Karen Carroll, Kristen Hansen, Geoffrey R. Heintzelman, Kenneth M. Wells, Kenneth J. Rhodes, J. Kent Barbay, N. H. Wallace, Devraj Chakravarty, Stefanie Rassnick, Brian C. Shook, Aihua Wang, Hall Daniel A, Kenneth C. Rupert, Xun Li, Vernon C. Alford, Derek A. Beauchamp, Shawn Branum, Kristi A. Leonard, Mark Ault, James L. Bullington

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:2868-2871

مصطلحات موضوعية: Receptor, Adenosine A2A, Clinical Biochemistry, Pharmaceutical Science, Ether, Adenosine A1 Receptor Antagonists, Pharmacology, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Adenosine A1 receptor, In vivo, Dopamine, Amide, Drug Discovery, medicine, Animals, Molecular Biology, Catalepsy, Neurotransmitter Agents, Receptor, Adenosine A1, Organic Chemistry, Antagonist, In vitro, Adenosine A2 Receptor Antagonists, Disease Models, Animal, Pyrimidines, chemistry, Adenosine a, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353b6f972a700b3aa70793fd134b85a1
https://doi.org/10.1016/j.bmcl.2010.03.024

المؤلفون: Tobias Schmid, Mark J. Macielag, Armin Roessler, Xun Li, Roger Faessler, Michele A. Weidner-Wells, Ronald K. Russell, Scott Youells, Eugene B. Grant

المصدر: Organic Preparations and Procedures International. 42:151-160

مصطلحات موضوعية: chemistry.chemical_classification, medicine.drug_class, Stereochemistry, Chemistry, Carboxylic acid, Organic Chemistry, medicine, Topoisomerase inhibitor, In vitro

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f47a2aca4cbe5e1f2bfe78c34778e6f2
https://doi.org/10.1080/00304941003680731

المؤلفون: Yongzheng Zhang, Ronald K. Russell, Xun Li, Raymond A. Ng, Zhihua Sui

المصدر: Organic Process Research & Development. 13:652-655

مصطلحات موضوعية: chemistry.chemical_compound, Benzonitrile, Aniline, Trifluoromethyl, chemistry, Diamine, Yield (chemistry), Organic Chemistry, Organic chemistry, Physical and Theoretical Chemistry, Benzene, High-performance liquid chromatography

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::33d2864150ffbcbd7ff0e87c64be3376
https://doi.org/10.1021/op9000498

المؤلفون: Ronald K. Russell, Rui Zhang, Alan Deangelis, Xun Li, Lubing Zhou, William V. Murray, Peifang Zhu, Gee-Hong Kuo, Patricia Pelton, Keith T. Demarest, Aihua Wang, Ellen Sieber-McMaster, Jun Xu

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:1101-1104

مصطلحات موضوعية: Models, Molecular, Molecular Structure, Chemistry, Stereochemistry, fungi, Organic Chemistry, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Stereoisomerism, Biochemistry, Glycolates, body regions, Structure-Activity Relationship, Thiazoles, Drug Design, Drug Discovery, Combinatorial Chemistry Techniques, Humans, Molecular Medicine, PPAR delta, skin and connective tissue diseases, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f159c6d2530b3ddac1625a71017bb584
https://doi.org/10.1016/j.bmcl.2008.12.113

المؤلفون: Dominique Depré, Wim Albert Alex Aelterman, Zhihua Sui, Xun Li, Dominic Ormerod, Andras Horvath, Nareshkumar F. Jain, Ronald K. Russell

المصدر: Organic Process Research & Development. 13:102-105

مصطلحات موضوعية: Chiral column chromatography, chemistry.chemical_compound, Chemistry, Acid catalyzed, Yield (chemistry), Organic Chemistry, Alkoxy group, Organic chemistry, Racemic mixture, Physical and Theoretical Chemistry, Enantiomer, Racemization, Naphthalene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d8f8e82beeee259d1ad9404fc112ffaf
https://doi.org/10.1021/op800237y

المؤلفون: William V. Murray, Hamish N. M. Ross, Lubing Zhou, Yan Zhang, Xiaoli Chen, Gee-Hong Kuo, Peifang Zhu, Keith T. Demarest, June Z. Xu, Aihua Wang, Ronald K. Russell, Maria Yang, Zhiyong Hu, Alan C. Gibbs, Lan Shen, Michael Reuman, Ellen Sieber-McMaster, Patricia Pelton

المصدر: Bioorganic & Medicinal Chemistry. 16:3321-3341

مصطلحات موضوعية: Transcriptional Activation, Agonist, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Administration, Oral, Biological Availability, Pharmaceutical Science, Biochemistry, Partial agonist, Chemical synthesis, GW501516, Mice, In vivo, Thiadiazoles, Drug Discovery, medicine, Animals, Potency, PPAR alpha, PPAR delta, Receptor, Molecular Biology, Metabolic Syndrome, Chemistry, Organic Chemistry, medicine.disease, Gene Expression Regulation, Nuclear receptor, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60a30416b11dc28b65e29f2fa4be3ba
https://doi.org/10.1016/j.bmc.2007.12.005

المؤلفون: Ronald K. Russell, Yongzheng Zhang, Scott Youells, Xun Li, Gee-Hong Kuo, Lan Shen, Zhiyong Hu, Michael Reuman

المصدر: Organic Process Research & Development. 11:1010-1014

مصطلحات موضوعية: Agonist, Trifluoromethyl, medicine.drug_class, Organic Chemistry, Medicinal chemistry, Sodium salt, Solvent, Dichlorobenzene, chemistry.chemical_compound, chemistry, medicine, Organic chemistry, Physical and Theoretical Chemistry, Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4337863a86c5a176075e322578c3cff0
https://doi.org/10.1021/op700141u

المؤلفون: Shawn Branum, Ramesh M. Kanojia, Xun Li, Robert Ma, Ronald K. Russell, Nareshkumar F. Jain, Scott Youells, Sandra Beish, Richard E. Adams, Michael Reuman, Zhihua Sui, Jerry R. Roberts

المصدر: Organic Process Research & Development. 11:414-421

مصطلحات موضوعية: Selective estrogen receptor modulator, Process development, Chemistry, Stereochemistry, Organic Chemistry, Physical and Theoretical Chemistry, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3f4cb618e3ea2c58fe9d5bdadb95eb45
https://doi.org/10.1021/op700020f

المؤلفون: Zhihua Sui, Ronald K. Russell, Ningyi Chen, Michael Reuman, Nareshkumar F. Jain, Jiayi Xu, Xun Li

المصدر: Tetrahedron Letters. 47:5909-5913

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Organic Chemistry, Drug Discovery, Electrophile, Alkoxy group, Organic chemistry, General Medicine, Ring (chemistry), Biochemistry, Combinatorial chemistry, Methyl group, Carbanion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdce82ef1aca86157743675b7d05ba68
https://doi.org/10.1016/j.tetlet.2006.06.047

المؤلفون: Nareshkumar F. Jain, Xun Li, Robert Ma, Ronald K. Russell, Zhihua Sui, Shawn Branum, and Jiayi Xu

المصدر: Organic Process Research & Development. 10:354-360

مصطلحات موضوعية: chemistry.chemical_compound, Bromine, chemistry, Organic Chemistry, chemistry.chemical_element, Halogenation, Organic chemistry, Physical and Theoretical Chemistry, Coumarin, Medicinal chemistry, Carbanion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e33043a5ed358f5effb8383940593dff
https://doi.org/10.1021/op050242p