المؤلفون: Tobias E. Larsson, Chisato Kameoka, Ikumi Nakajo, Yuta Taniuchi, Satoshi Yoshida, Tadao Akizawa, Ronald A. Smulders

المصدر: Kidney International Reports, Vol 3, Iss 1, Pp 73-80 (2018)

مصطلحات موضوعية: end-stage renal disease, hemodialysis, hyperphosphatemia, NPT-IIb inhibitor, pharmacokinetics, phase 1 trial, Diseases of the genitourinary system. Urology, RC870-923

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024917303455; https://doaj.org/toc/2468-0249

URL الوصول: https://doaj.org/article/6e7d7f1195d044288303d13fc368a64f

المؤلفون: Ronald A. Smulders, Neila N. Smith, Walter J. Smith, Timothy J. Hoon

المصدر: Journal of Pharmacological Sciences, Vol 103, Iss 1, Pp 67-74 (2007)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861319343403; https://doaj.org/toc/1347-8613

URL الوصول: https://doaj.org/article/ead78f7113bd43bdafcfb18391459d63

المؤلفون: Mototsugu Ito, Tomasz Wojtkowski, Ronald A. Smulders, Akihiro Yamada, Ronald Goldwater, Akira Koibuchi, Tolga Uz, Sitra Tauscher-Wisniewski, Gerard J. Marek

المصدر: Muscle & Nerve. 65:110-120

مصطلحات موضوعية: Physiology, business.industry, Pharmacology, Placebo, Bioavailability, Cellular and Molecular Neuroscience, Pharmacokinetics, Tolerability, Physiology (medical), Pharmacodynamics, Medicine, Peroxisome proliferator-activated receptor delta, Neurology (clinical), Adverse effect, business, Receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cbdea70432c6f16acb2f20525a7f7d76
https://doi.org/10.1002/mus.27436

المؤلفون: Mototsugu, Ito, Sitra, Tauscher-Wisniewski, Ronald A, Smulders, Tomasz, Wojtkowski, Akihiro, Yamada, Akira, Koibuchi, Tolga, Uz, Gerard J, Marek, Ronald D, Goldwater

المصدر: Musclenerve. 65(1)

مصطلحات موضوعية: Adult, Dose-Response Relationship, Drug, Double-Blind Method, Sulfates, Area Under Curve, Imidazoles, Administration, Oral, Humans, PPAR delta, Caproates, Healthy Volunteers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f6f14c70caeea1680b01d375a878d446
https://pubmed.ncbi.nlm.nih.gov/34642949

المؤلفون: Ronald A. Smulders, Chieri Higashitani, Christopher Lademacher, Yoshiya Tanaka, Masako Saito, Yuichiro Kaneko, Jay Erdman, Tsutomu Takeuchi

المصدر: Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-11 (2020)

مصطلحات موضوعية: medicine.medical_specialty, Integrins, lcsh:Diseases of the musculoskeletal system, Exacerbation, Placebo-controlled study, Placebo, Antibodies, Monoclonal, Humanized, Gastroenterology, Arthritis, Rheumatoid, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Internal medicine, medicine, Humans, Biological products, Adverse effect, 030203 arthritis & rheumatology, Integrin alpha-9, human, business.industry, medicine.disease, Synovial membrane, Synoviocytes, Rheumatology, Antirheumatic agents, Methotrexate, Treatment Outcome, Extracellular matrix proteins, Rheumatoid arthritis, Pharmacodynamics, Drug Therapy, Combination, lcsh:RC925-935, business, 030215 immunology, medicine.drug, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d0d05fbd1cea599ef259cac00cf498
http://europepmc.org/articles/PMC7579887

المؤلفون: Ronald A. Smulders, Tobias E. Larsson, Yuta Taniuchi, Chisato Kameoka, Tadao Akizawa, Satoshi Yoshida, Ikumi Nakajo

المصدر: Kidney International Reports, Vol 3, Iss 1, Pp 73-80 (2018)
Kidney International Reports

مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Urinary system, 030232 urology & nephrology, 030204 cardiovascular system & hematology, lcsh:RC870-923, Gastroenterology, End stage renal disease, Excretion, 03 medical and health sciences, chemistry.chemical_compound, Hyperphosphatemia, 0302 clinical medicine, phase 1 trial, Pharmacokinetics, Clinical Research, Internal medicine, medicine, NPT-IIb inhibitor, hyperphosphatemia, end-stage renal disease, hemodialysis, business.industry, Phosphate, medicine.disease, lcsh:Diseases of the genitourinary system. Urology, Endocrinology, chemistry, Tolerability, Nephrology, Hemodialysis, business, pharmacokinetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aeec6f3ddb4d0f5844e3307eafe59dc
http://www.sciencedirect.com/science/article/pii/S2468024917303455

المؤلفون: Fiona E. Watt, Nancy E Lane, Allam Fakhoury, Hélène Jacobs, Mary Beth Blauwet, Ronald A. Smulders

المصدر: Osteoarthritis and cartilage, vol 27, iss 11

مصطلحات موضوعية: 0301 basic medicine, Male, Aging, Anti-Inflammatory Agents, Arthritis, Osteoarthritis, Physical function, 0302 clinical medicine, Naproxen, Clinical endpoint, Medicine, Orthopedics and Sports Medicine, Pain Measurement, Painful knee, Anti-Inflammatory Agents, Non-Steroidal, Pain Research, Osteoarthritis, Knee, Middle Aged, Arthralgia, Treatment Outcome, trkA, 6.1 Pharmaceuticals, Female, Chronic Pain, Non-Steroidal, medicine.drug, Receptor, Adult, medicine.medical_specialty, WOMAC, Adolescent, Clinical Trials and Supportive Activities, Clinical Sciences, Biomedical Engineering, Pain, TrkA inhibitor, Placebo, 03 medical and health sciences, Young Adult, Rheumatology, Double-Blind Method, Clinical Research, Internal medicine, Humans, Knee, Receptor, trkA, Aged, 030203 arthritis & rheumatology, business.industry, Evaluation of treatments and therapeutic interventions, Human Movement and Sports Sciences, medicine.disease, Arthritis & Rheumatology, 030104 developmental biology, Musculoskeletal, ASP7962, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1280b328692082932365edb91da09855
https://ora.ox.ac.uk/objects/uuid:ad26e7c0-bec8-4816-b4f7-9de9dc5caee6

المؤلفون: Beth Cywin, Vicki Santos, Rick Malley, Laura L. Kovanda, Gurunadh Chichili, George R. Siber, Shite Sebastian, Ronald A. Smulders, Frank J. Malinoski

المصدر: Open Forum Infectious Diseases

مصطلحات موضوعية: myalgia, Serotype, biology, business.industry, Surrogate endpoint, Immunogenicity, Immunoglobulin G, Infectious Diseases, AcademicSubjects/MED00290, Oncology, Antigen, Pneumococcal vaccine, Immunology, Poster Abstracts, biology.protein, Medicine, medicine.symptom, Adverse effect, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdadf551bf0300990137b6517ce5c8b
http://europepmc.org/articles/PMC7776618

المؤلفون: Fumihiko Ushigome, James Keirns, Lisa C. Plumb, Robert Townsend, Takeshi Kadokura, Walter Krauwinkel, Kenneth C. Lasseter, Ronald A. Smulders, Wenhui Zhang

المصدر: Clinical Drug Investigation. 33:489-496

مصطلحات موضوعية: Male, medicine.medical_specialty, Sodium, chemistry.chemical_element, Thiophenes, Pharmacology, chemistry.chemical_compound, Pharmacotherapy, Glucosides, Sodium-Glucose Transporter 2, Pharmacokinetics, Internal medicine, Humans, Medicine, Pharmacology (medical), Sodium-Glucose Transporter 2 Inhibitors, business.industry, Hepatic impairment, Type 2 Diabetes Mellitus, Transporter, General Medicine, Middle Aged, Ipragliflozin, Endocrinology, Liver, chemistry, Female, SGLT2 Inhibitor, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcc9be8bf4ebe5b13107096e050c140
https://doi.org/10.1007/s40261-013-0089-6

المؤلفون: Takeshi Kadokura, Ronald A. Smulders, Stephan A. Veltkamp, Ele Ferrannini

المصدر: Diabetes Care. 36:1260-1265

مصطلحات موضوعية: Advanced and Specialized Nursing, Glycosuria, Kidney, medicine.medical_specialty, endocrine system diseases, business.industry, Endocrinology, Diabetes and Metabolism, nutritional and metabolic diseases, Renal function, Type 2 diabetes, medicine.disease, Excretion, chemistry.chemical_compound, Ipragliflozin, medicine.anatomical_structure, Endocrinology, chemistry, Internal medicine, Diabetes mellitus, Sodium/Glucose Cotransporter 2, Internal Medicine, Medicine, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4e3fa9678a33d87b1288c7ad5e6d31f5
https://doi.org/10.2337/dc12-1503

المؤلفون: Wenhui Zhang, J. van Dijk, Walter Krauwinkel, James Keirns, Ronald A. Smulders, Stephan A. Veltkamp, Takeshi Kadokura

المصدر: Diabetes, Obesity and Metabolism. 14:937-943

مصطلحات موضوعية: business.industry, Endocrinology, Diabetes and Metabolism, Area under the curve, Cmax, Pharmacology, Sitagliptin Phosphate, Glimepiride, chemistry.chemical_compound, Endocrinology, Ipragliflozin, chemistry, Pharmacokinetics, Sitagliptin, Internal Medicine, medicine, business, Pioglitazone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d048adc6a333e965e0f3ebb78b4d8f76
https://doi.org/10.1111/j.1463-1326.2012.01624.x

المؤلفون: Neila Smith, Walter Krauwinkel, Piet Swart, Ronald A. Smulders

المصدر: Basic Toxicology. 99:33-36

مصطلحات موضوعية: Adult, Male, Solifenacin Succinate, Quinuclidines, Antifungal Agents, Adolescent, Cmax, Muscarinic Antagonists, Pharmacology, Toxicology, Pharmacokinetics, Tetrahydroisoquinolines, medicine, Humans, Drug Interactions, Adverse effect, Cross-Over Studies, Solifenacin, Chemistry, Area under the curve, General Medicine, Middle Aged, Crossover study, Ketoconazole, Area Under Curve, Female, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed42c6770fb14643d5fe27bfd135185
https://doi.org/10.1111/j.1742-7843.2006.pto_285.x

المؤلفون: Mirjam E. Kuipers, Walter Krauwinkel, Timothy J. Hoon, Ronald A. Smulders

المصدر: Journal of Pharmacological Sciences, Vol 102, Iss 4, Pp 405-412 (2006)

مصطلحات موضوعية: Adult, Male, Solifenacin Succinate, Quinuclidines, medicine.medical_specialty, Time Factors, Adolescent, Metabolic Clearance Rate, Cmax, Urology, Administration, Oral, Muscarinic Antagonists, Urine, Pharmacology, Severity of Illness Index, Pharmacokinetics, Open label study, Tetrahydroisoquinolines, medicine, Humans, Aged, Aged, 80 and over, Solifenacin, business.industry, Liver Diseases, Hepatic impairment, lcsh:RM1-950, Middle Aged, medicine.disease, lcsh:Therapeutics. Pharmacology, Overactive bladder, Area Under Curve, Molecular Medicine, Female, business, Follow-Up Studies, Half-Life, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db63a03744a31e265e18151c5154ecc6
https://doi.org/10.1254/jphs.fp0060311

المؤلفون: Walter Krauwinkel, Piet Swart, Ronald A. Smulders, Moses Huang

المصدر: The Journal of Clinical Pharmacology. 44:1023-1033

مصطلحات موضوعية: Adult, Male, Solifenacin Succinate, Quinuclidines, Adolescent, Blood Pressure, Muscarinic Antagonists, Pharmacology, Double-Blind Method, Pharmacokinetics, Heart Rate, Tetrahydroisoquinolines, Humans, Medicine, Pharmacology (medical), Adverse effect, Vision, Ocular, Solifenacin, Dose-Response Relationship, Drug, business.industry, Area under the curve, Half-life, Middle Aged, Dose–response relationship, Tolerability, Area Under Curve, Salivation, business, Half-Life, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1955d446f179d29e6a19e5306887d3
https://doi.org/10.1177/0091270004267592

المؤلفون: Ronald A. Smulders, Hans Mulder, Walter Krauwinkel, Taisuke Uchida

المصدر: British Journal of Clinical Pharmacology. 58:4-7

مصطلحات موضوعية: Adult, Male, Detrusor muscle, Solifenacin Succinate, Quinuclidines, medicine.medical_specialty, Adolescent, Cmax, Urology, Muscarinic Antagonists, Food-Drug Interactions, Pharmacokinetics, Oral administration, Tetrahydroisoquinolines, Internal medicine, medicine, Humans, Pharmacology (medical), Pharmacology, Cross-Over Studies, Solifenacin, business.industry, Middle Aged, medicine.disease, Crossover study, Endocrinology, medicine.anatomical_structure, Overactive bladder, Food, Area Under Curve, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe77a558ec3a7d4c9708bacd0846cc4f
https://doi.org/10.1111/j.1365-2125.2004.02097.x

المؤلفون: Ronald A. Smulders, James Keirns, Stefanie Leeflang, Ikumi Nakajo, Yuta Taniuchi, Takeshi Kadokura, Wenhui Zhang, Walter Krauwinkel

المصدر: Clinical pharmacokinetics. 53(11)

مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Type 2 diabetes, Thiophenes, Pharmacology, chemistry.chemical_compound, Mitiglinide, Glucosides, Japan, Sodium-Glucose Transporter 2, Internal medicine, medicine, Humans, Hypoglycemic Agents, Pharmacology (medical), Renal Insufficiency, Sodium-Glucose Transporter 2 Inhibitors, Aged, Glycated Hemoglobin, business.industry, Miglitol, Middle Aged, medicine.disease, Glimepiride, Endocrinology, Ipragliflozin, chemistry, Diabetes Mellitus, Type 2, Pharmacodynamics, Sitagliptin, Female, business, Pioglitazone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63645a34f669e01b679d93cd359a8b09
https://pubmed.ncbi.nlm.nih.gov/25316572

المؤلفون: Ab J.M. Donker, Johan M. TeKoppele, Ronald A. Smulders, Casper G. Schalkwijk, Coen D.A. Stehouwer, Victor W.M. van Hinsbergh

المصدر: Thrombosis and Haemostasis. 80:52-57

مصطلحات موضوعية: medicine.medical_specialty, biology, Endothelium, business.industry, Hematology, Diabetic angiopathy, medicine.disease, Excretion, chemistry.chemical_compound, Endocrinology, medicine.anatomical_structure, chemistry, Von Willebrand factor, Diabetes mellitus, Internal medicine, medicine, biology.protein, Advanced glycation end-product, Endothelial dysfunction, Pentosidine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f00aff57cad32509848ab1a1c3f3d371
https://doi.org/10.1055/s-0037-1615138

المؤلفون: Coen D.A. Stehouwer, Mieke Aarsen, Ronald A. Smulders, J. Lambert, Ab J.M. Donker

المصدر: Diabetes Care. 21:99-103

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Hemodynamics, Blood Pressure, Muscle, Smooth, Vascular, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Albuminuria, Humans, Triglycerides, Aged, Ultrasonography, Glycated Hemoglobin, Advanced and Specialized Nursing, Analysis of Variance, Proteinuria, business.industry, Vascular disease, Cholesterol, HDL, Smoking, Cholesterol, LDL, Middle Aged, medicine.disease, Elasticity, Carotid Arteries, Cholesterol, Diabetes Mellitus, Type 1, Endocrinology, Blood pressure, Arterial stiffness, Cardiology, Female, Microalbuminuria, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825b0d8f2e4fd735f607bb320555d9a4
https://doi.org/10.2337/diacare.21.1.99

المؤلفون: Shigeru Kageyama, Satoshi Yoshida, Itsuro Nagase, Atsushi Utsuno, Ronald A. Smulders, Noriko Akiyama, Atsunori Kashiwagi, Kenichi Kazuta, Takeshi Kadokura

المصدر: Diabetes research and clinical practice. 106(1)

مصطلحات موضوعية: Adult, Blood Glucose, Male, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Type 2 diabetes, Thiophenes, Pharmacology, chemistry.chemical_compound, Young Adult, Endocrinology, Pharmacokinetics, Asian People, Double-Blind Method, Glucosides, Diabetes mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Tissue Distribution, Aged, Dose-Response Relationship, Drug, business.industry, Insulin, Area under the curve, General Medicine, Middle Aged, medicine.disease, Ipragliflozin, Postprandial, chemistry, Diabetes Mellitus, Type 2, Pharmacodynamics, Area Under Curve, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b402f59d9fa58bba73dffb46d65c5106
https://pubmed.ncbi.nlm.nih.gov/25149596

المؤلفون: James Keirns, Albert Dietz, Ronald A. Smulders, Takeshi Kadokura, Wenhui Zhang, Walter Krauwinkel, Anura Abeyratne

المصدر: Clinical therapeutics. 35(8)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Moxifloxacin, Thiophenes, Placebo, QT interval, Gastroenterology, Drug Administration Schedule, White People, chemistry.chemical_compound, Electrocardiography, Young Adult, Double-Blind Method, Glucosides, Heart Conduction System, Heart Rate, Internal medicine, Heart rate, Medicine, Humans, Pharmacology (medical), Dosing, Pharmacology, Aza Compounds, Cross-Over Studies, Dose-Response Relationship, Drug, business.industry, Assay sensitivity, Middle Aged, Crossover study, Healthy Volunteers, Black or African American, Ipragliflozin, chemistry, Anesthesia, Quinolines, Female, business, medicine.drug, Fluoroquinolones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebde9efb29b70a8a67e924755b9751d1
https://pubmed.ncbi.nlm.nih.gov/23910665