المؤلفون: Mary K. Chaves, Ron C. Kelly, Jacqueline E. Milne, Susan E. Burke

المصدر: Pharmaceutical Development and Technology. 27:511-524

مصطلحات موضوعية: Excipients, Pharmaceutical Preparations, X-Ray Diffraction, Chemistry, Pharmaceutical, Wettability, Technology, Pharmaceutical, Pharmaceutical Science, General Medicine, Powders

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19dd6b2827e6b3ff8c2bff81e4b3d018
https://doi.org/10.1080/10837450.2022.2084105

المؤلفون: Gwenaella Rescourio, Ana Z. Gonzalez, Salman Jabri, Brian Belmontes, Gordon Moody, Doug Whittington, Xin Huang, Sean Caenepeel, Mario Cardozo, Alan C. Cheng, David Chow, Hannah Dou, Adrie Jones, Ron C. Kelly, Yihong Li, Mike Lizarzaburu, Mei-Chu Lo, Rommel Mallari, Cesar Meleza, Yosup Rew, Scott Simonovich, Daqing Sun, Simon Turcotte, Xuelei Yan, Simon G. Wong, Evelyn Yanez, Manuel Zancanella, Jonathan Houze, Julio C. Medina, Paul E. Hughes, Sean P. Brown

المصدر: Journal of Medicinal Chemistry. 62:10258-10271

مصطلحات موضوعية: Sulfonamides, Administration, Oral, Biological Availability, Mice, Nude, Antineoplastic Agents, Hydrogen Bonding, Crystallography, X-Ray, Xenograft Model Antitumor Assays, Rats, Sprague-Dawley, Structure-Activity Relationship, Drug Stability, Cell Line, Tumor, Drug Design, Drug Discovery, Animals, Humans, Myeloid Cell Leukemia Sequence 1 Protein, Molecular Medicine, Female, Multiple Myeloma, Phenylacetates

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e56bfd1df312774368ff5b90efcd7cc
https://doi.org/10.1021/acs.jmedchem.9b01310

المؤلفون: Jon Hilden, Timothy T. Kramer, John Strong, Ilgaz Akseli, Chen Mao, Jeffrey M. Katz, Frederick Osei-Yeboah, Ron C. Kelly

المصدر: Journal of Pharmaceutical Sciences. 108:1081-1084

مصطلحات موضوعية: Reproducibility, Materials science, Chemistry, Pharmaceutical, Drug Compounding, Sample (material), Hausner ratio, Analytical chemistry, Datasets as Topic, Reproducibility of Results, Pharmaceutical Science, 02 engineering and technology, 021001 nanoscience & nanotechnology, 030226 pharmacology & pharmacy, Bulk density, Excipients, 03 medical and health sciences, 0302 clinical medicine, Powder bed, Range (statistics), Particle Size, Powders, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4ad595e38ec36978ee02c5cb014663
https://doi.org/10.1016/j.xphs.2018.10.009

المؤلفون: Iain D. G. Campuzano, Xiaolin Hao, Brian Lucas, Tisha San Miguel, Deanna Mohn, Kirk Henne, Benjamin Fisher, Minna Bui, Mario G. Cardozo, Robert S. Foti, Ron C. Kelly, Christine Vissinga, Thuy B. Tran, John D. McCarter, Leeanne Zalameda, Daniela Metz, Douglas A. Whittington, Sharon Wannberg, Yi-Ling Hu, John Whoriskey, Julio C. Medina, Felix Gonzalez-Lopez de Turiso, Timothy D. Cushing, Xuxia Zhang, Lawrence R. McGee, Michael G. Johnson, Xiao He, Gang Yu, Michelle C. Dunn, Jason Duquette, Youngsook Shin

المصدر: Journal of Medicinal Chemistry. 59:7252-7267

مصطلحات موضوعية: 0301 basic medicine, biology, Stereochemistry, Chemistry, Quinoline, In vitro, Bioavailability, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Pharmacokinetics, In vivo, Pharmacodynamics, Drug Discovery, biology.protein, Molecular Medicine, Potency, Keyhole limpet hemocyanin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5b68313a948b3dc2d85bb6149f781869
https://doi.org/10.1021/acs.jmedchem.6b00827

المؤلفون: Roger Zanon, Naveen K. Thakral, Ron C. Kelly, Seema Thakral

المصدر: Journal of pharmaceutical sciences. 107(12)

مصطلحات موضوعية: Diffraction, Materials science, Drug Compounding, Lasers, Pharmaceutical Science, Nanotechnology, 02 engineering and technology, Equipment Design, 021001 nanoscience & nanotechnology, 030226 pharmacology & pharmacy, Quality by Design, Phase Transition, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Pharmaceutical Preparations, X-Ray Diffraction, X-ray crystallography, 0210 nano-technology, Crystallization, Powder Diffraction, Synchrotrons

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6c7772f293c3e9205719ac22403021
https://pubmed.ncbi.nlm.nih.gov/30145209

المؤلفون: Andrew Tasker, Andreas Reichelt, Yi-Ling Hu, Deanna Mohn, John McCarter, Ben Fisher, Robert M. Rzasa, Yi Chen, Julio C. Medina, Gang Yu, Sharon Wannberg, Brian Lucas, Ron C. Kelly, Jennifer Seganish, Felix Gonzalez-Lopez de Turiso, Xiaolin Hao, Kristin L. Andrews, Douglas A. Whittington, Matthew Frank Brown, Dawei Zhang, Youngsook Shin, Mario G. Cardozo, Jason Duquette, Robert C. Wahl, Leeanne Zalameda, Daniela Metz, Vatee Pattaropong, Michael G. Johnson, Tisha San Miguel, Randall W. Hungate, John Whoriskey, Lawrence R. McGee, Timothy D. Cushing, Kirk Henne, Liping H. Pettus, Xiao He

المصدر: Journal of Medicinal Chemistry. 58:480-511

مصطلحات موضوعية: Models, Molecular, Adenosine, Class I Phosphatidylinositol 3-Kinases, Stereochemistry, Mice, Transgenic, Pharmacology, Crystallography, X-Ray, Autoimmune Diseases, Structure-Activity Relationship, In vivo, Drug Discovery, Sf9 Cells, medicine, Animals, Humans, Structure–activity relationship, Protein Kinase Inhibitors, IC50, Cells, Cultured, Whole blood, Inflammation, Autoimmune disease, Mice, Inbred BALB C, Molecular Structure, Drug discovery, Kinase, Chemistry, medicine.disease, Protein Structure, Tertiary, Disease Models, Animal, Models, Chemical, Rats, Inbred Lew, Quinolines, Molecular Medicine, Female, Amine gas treating, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f464b8458b3d559ce036ed30580e01
https://doi.org/10.1021/jm501624r

المؤلفون: Tian Wu, Jan Wahlstrom, Chung John Inn, Fernando Alvarez-Nunez, Ron C. Kelly, Benjamin Wu

المصدر: Journal of pharmaceutical sciences. 106(3)

مصطلحات موضوعية: 0301 basic medicine, business.industry, Pharmaceutical Science, Administration, Oral, 030226 pharmacology & pharmacy, Models, Biological, Biotechnology, Gastrointestinal absorption, Modeling and simulation, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Risk analysis (engineering), Drug development, Pharmaceutical Preparations, Gastrointestinal Absorption, Medicine, Humans, Computer Simulation, business, Physiological Phenomenon, Physiological Phenomena, Pharmaceutical industry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb7f77c7dcfac327cc041f3e8b2df79
https://pubmed.ncbi.nlm.nih.gov/27915208

المؤلفون: Felix, Gonzalez-Lopez de Turiso, Xiaolin, Hao, Youngsook, Shin, Minna, Bui, Iain D G, Campuzano, Mario, Cardozo, Michelle C, Dunn, Jason, Duquette, Benjamin, Fisher, Robert S, Foti, Kirk, Henne, Xiao, He, Yi-Ling, Hu, Ron C, Kelly, Michael G, Johnson, Brian S, Lucas, John, McCarter, Lawrence R, McGee, Julio C, Medina, Daniela, Metz, Tisha, San Miguel, Deanna, Mohn, Thuy, Tran, Christine, Vissinga, Sharon, Wannberg, Douglas A, Whittington, John, Whoriskey, Gang, Yu, Leeanne, Zalameda, Xuxia, Zhang, Timothy D, Cushing

المصدر: Journal of medicinal chemistry. 59(15)

مصطلحات موضوعية: Models, Molecular, B-Lymphocytes, Dose-Response Relationship, Drug, Molecular Structure, Pyridines, Class Ia Phosphatidylinositol 3-Kinase, Mice, Structure-Activity Relationship, Drug Discovery, Quinolines, Animals, Humans, Protein Kinase Inhibitors, Phosphoinositide-3 Kinase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a242cbf7d7efba8c63b94dcec247686e
https://pubmed.ncbi.nlm.nih.gov/27411843

المؤلفون: Mary K. Stanton, Ron C. Kelly, Matthew Peterson, Richard J. Staples, Alan C. Cheng

المصدر: CrystEngComm. 13:1170-1180

مصطلحات موضوعية: Trifluoromethyl, Chemistry, Stereochemistry, General Chemistry, Crystal structure, Condensed Matter Physics, Cocrystal, law.invention, Crystal, Crystallography, chemistry.chemical_compound, law, General Materials Science, Crystallization, Hydrate, Single crystal, Acetamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::47c575d0a5a0067e5c6c8f34028bbf25
https://doi.org/10.1039/c0ce00544d

المؤلفون: Hua Tu, Lisa Julian, Nigel Walker, Maren Gulsrud Willcockson, Yosup Rew, Michael DeGraffenreid, Zhulun Wang, Juan C. Jaen, Daqing Sun, Ron C. Kelly, Athena Sudom, Seb Caille, Jacob Kaizerman, Jay P. Powers, Xuelei Yan, Qiuping Ye, Stefania Ursu, Ben Jiang, Felix Gonzalez-Lopez de Turiso, Randall W. Hungate, Dustin McMinn

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:405-410

مصطلحات موضوعية: medicine.drug_class, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Carboxamide, Crystallography, X-Ray, Biochemistry, Chemical synthesis, 11β hsd1 inhibitors, Structure-Activity Relationship, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Binding Sites, biology, Chemistry, Organic Chemistry, Highly selective, Combinatorial chemistry, Rats, Macaca fascicularis, Enzyme, Enzyme inhibitor, Benzamides, Microsomes, Liver, biology.protein, Molecular Medicine, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d541a6a690483f033c76a34f9400098
https://doi.org/10.1016/j.bmcl.2010.10.129

المؤلفون: Matthew Peterson, Adria E. Colletti, Eric J. Munson, Mary K. Stanton, Y.-H. Kiang, John Roberts, Mary C. Wells, Meghan Langley, Ron C. Kelly

المصدر: Journal of Pharmaceutical Sciences. 99:3769-3778

مصطلحات موضوعية: Male, Stereochemistry, Carboxylic acid, TRPV Cation Channels, Pharmaceutical Science, Crystallography, X-Ray, Cinnamic acid, Rats, Sprague-Dawley, chemistry.chemical_compound, Pharmacokinetics, Amide, Animals, Benzothiazoles, Benzamide, Dissolution, Benzoic acid, chemistry.chemical_classification, Free base, Benzoic Acid, Rats, Pyrimidines, Solubility, chemistry, Cinnamates, Benzamides, Crystallization, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6601f6465d4d105e8e275908b03c1738
https://doi.org/10.1002/jps.22181

المؤلفون: Ron C. Kelly, Naír Rodríguez-Hornedo

المصدر: Organic Process Research & Development. 13:1291-1300

مصطلحات موضوعية: Chemistry, Organic Chemistry, Nucleation, Carbamazepine, law.invention, Molecular recognition, law, medicine, Anhydrous, Organic chemistry, Physical and Theoretical Chemistry, Solubility, Crystallization, Solvent effects, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6121c7039d5e3739953d7a6da90f2aaa
https://doi.org/10.1021/op900133z

المؤلفون: George Zografi, Igor Ivanisevic, Simon Bates, David Engers, Ron C. Kelly, Ann Newman

المصدر: Journal of Pharmaceutical Sciences. 97:4840-4856

مصطلحات موضوعية: Materials science, Calorimetry, Differential Scanning, Polymers, Indomethacin, Evaporation, Analytical chemistry, Povidone, Trehalose, Pharmaceutical Science, Dextrans, Miscibility, Amorphous solid, law.invention, Freeze Drying, Differential scanning calorimetry, Solubility, X-Ray Diffraction, law, Phase (matter), Thermodynamics, Powders, Crystallization, Glass transition, Powder diffraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5106013ba9fcfa19ec73d276ba39b5a
https://doi.org/10.1002/jps.21352

المؤلفون: Igor Ivanisevic, Simon Bates, Paul J. Schields, George Zografi, Ann Newman, Ron C. Kelly

المصدر: Journal of Pharmaceutical Sciences. 96:1418-1433

مصطلحات موضوعية: Models, Molecular, Time Factors, Chemistry, Pharmaceutical, Drug Compounding, Molecular Conformation, Pharmaceutical Science, Crystal structure, Crystallography, X-Ray, Crystal, Crystallinity, Raffinose, Technology, Pharmaceutical, Desiccation, Chemistry, Water, Pair distribution function, Crystallographic defect, Amorphous solid, Crystallography, Models, Chemical, Thermodynamics, Powders, Crystallization, Hydrate, Powder Diffraction, Powder diffraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428f028854b098c06496ba4eb73533c0
https://doi.org/10.1002/jps.20944

المؤلفون: Yi-Ling Hu, Leeanne Zalameda, Daniela Metz, Julia Suchomel, Thuy B. Tran, Gang Yu, Jason Duquette, John McCarter, Xuxia Zhang, Youngsook Shin, Simon Wong, Julio C. Medina, Sharon Wannberg, Timothy D. Cushing, Tisha San Miguel, Mario G. Cardozo, Lawrence R. McGee, Ron C. Kelly, Christine Vissinga, Deanna Mohn, John Whoriskey, Douglas A. Whittington, Kirk Henne, Xiao He

المصدر: Journal of medicinal chemistry. 59(1)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Benzimidazole, B-cell receptor, chemical and pharmacologic phenomena, Crystallography, X-Ray, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Pharmacokinetics, In vivo, Drug Discovery, Structure–activity relationship, Animals, Humans, Protein Kinase Inhibitors, Phosphoinositide-3 Kinase Inhibitors, B-Lymphocytes, biology, Chemistry, In vitro, Bioavailability, Rats, 030104 developmental biology, Biochemistry, Immunoglobulin M, Immunoglobulin G, Hemocyanins, biology.protein, Molecular Medicine, Benzimidazoles, Keyhole limpet hemocyanin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd418762bb2f427cfe73c0b9127b325
https://pubmed.ncbi.nlm.nih.gov/26652588

المؤلفون: Matthew L. Peterson, Mary K. Stanton, Ron C. Kelly, Richard Staples, Alan Cheng

المصدر: CrystEngComm; Feb2011, Vol. 13 Issue 4, p1170-1180, 11p

مصطلحات موضوعية: SOLID state chemistry, MOLECULAR structure, ACETAMIDE, POLYMORPHISM (Crystallography), HYDRATES, MECHANICAL alloying, SOLUTION (Chemistry), X-ray diffraction