المؤلفون: Antony D. St-Jacques, Joshua M. Rodriguez, Matthew G. Eason, Scott M. Foster, Safwat T. Khan, Adam M. Damry, Natalie K. Goto, Michael C. Thompson, Roberto A. Chica

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c5dbd4d40ae840a6a59e282e97bd6c6b

المؤلفون: Mykhaylo Slobodyanyuk, Jesús A. Banda-Vázquez, Mackenzie J. Thompson, Rebecca A. Dean, John E. Baenziger, Roberto A. Chica, Corrie J. B. daCosta

المصدر: Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/a19626476cd2418fa92c83a006ffee5b

المؤلفون: Aron Broom, Rojo V. Rakotoharisoa, Michael C. Thompson, Niayesh Zarifi, Erin Nguyen, Nurzhan Mukhametzhanov, Lin Liu, James S. Fraser, Roberto A. Chica

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/7439f4de0efc41d198a2176b909a8ff0

المؤلفون: Andrew C. Hemmert, Tamara C. Otto, Roberto A. Chica, Monika Wierdl, Jonathan S. Edwards, Steven M. Lewis, Carol C. Edwards, Lyudmila Tsurkan, C. Linn Cadieux, Shane A. Kasten, John R. Cashman, Stephen L. Mayo, Philip M. Potter, Douglas M. Cerasoli, Matthew R. Redinbo

المصدر: PLoS ONE, Vol 7, Iss 1 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3266938; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/48227b2df6724d49b81ec197ceefeed0

المؤلفون: Sandrine Legault, Derek P. Fraser-Halberg, Ralph L. McAnelly, Matthew G. Eason, Michael C. Thompson, Roberto A. Chica

المصدر: Chemical Science. 13:1408-1418

مصطلحات موضوعية: General Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e4d2ff68ca6c28d837740154ad7bf9c1
https://doi.org/10.1039/d1sc05088e

المؤلفون: Roberto A Chica, Brett M Garabedian

المصدر: Protein Engineering, Design and Selection. 36

مصطلحات موضوعية: Bioengineering, Molecular Biology, Biochemistry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4537ecb9d2223533fe383af141c6da37
https://doi.org/10.1093/protein/gzad004

المؤلفون: Antony D. St-Jacques, Joshua M. Rodriguez, Matthew G. Eason, Scott M. Foster, Safwat T. Khan, Adam M. Damry, Natalie K. Goto, Michael C. Thompson, Roberto A. Chica

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bc851cb51fb15e02aeab27097d7f72cf
https://doi.org/10.1101/2022.09.16.508321

المؤلفون: Michael Ong, Bryan Lo, Marie-Ève Wedge, Carolina S. Ilkow, John C. Bell, Catia Cemeus, Oliver Varette, Aron Broom, Benjamin McSweeney, Bruce F. Burns, Harold L. Atkins, Brian J Laight, Julia Petryk, Brian A. Keller, Jean-Simon Diallo, Carolyn Nessim, Roberto A. Chica

المصدر: Journal of Cancer Research and Clinical Oncology. 147:1365-1378

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_specialty, In silico, Chemical library, Loss of heterozygosity, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, neoplasms, Cobimetinib, Hematology, business.industry, Drug discovery, Melanoma, General Medicine, medicine.disease, 3. Good health, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer research, Cellular model, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6ae1f24727701df369e59dd2c32a58f0
https://doi.org/10.1007/s00432-021-03545-2

المؤلفون: Sandrine, Legault, Derek P, Fraser-Halberg, Ralph L, McAnelly, Matthew G, Eason, Michael C, Thompson, Roberto A, Chica

المصدر: Chemical science. 13(5)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f96c9abb09e43dbe73a38b9e5269ad99
https://pubmed.ncbi.nlm.nih.gov/35222925

المؤلفون: Marie-Ève C. Eyahpaise, Antony D. St-Jacques, Roberto A. Chica

المصدر: ACS Catalysis. 9:5480-5485

مصطلحات موضوعية: chemistry.chemical_classification, 010405 organic chemistry, Protein design, General Chemistry, Protein engineering, 010402 general chemistry, 01 natural sciences, Catalysis, 0104 chemical sciences, Transaminase, Amino acid, Biochemistry, chemistry, Enzyme specificity, Biocatalysis, Computational design

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d2e7cf37da9e3ce295bf496fdaec1869
https://doi.org/10.1021/acscatal.9b01464

المؤلفون: Brian A, Keller, Brian J, Laight, Oliver, Varette, Aron, Broom, Marie-Ève, Wedge, Benjamin, McSweeney, Catia, Cemeus, Julia, Petryk, Bryan, Lo, Bruce, Burns, Carolyn, Nessim, Michael, Ong, Roberto A, Chica, Harold L, Atkins, Jean-Simon, Diallo, Carolina S, Ilkow, John C, Bell

المصدر: Journal of cancer research and clinical oncology. 147(5)

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, Skin Neoplasms, Carcinogenesis, Mice, Nude, Antineoplastic Agents, Mice, SCID, Mice, Drug Development, Mice, Inbred NOD, Cell Line, Tumor, Mutation, Animals, Humans, Precision Medicine, Transcriptome, Melanoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::675ef1e0dbafb16cd47b6a9f4864c9c1
https://pubmed.ncbi.nlm.nih.gov/33555379

المؤلفون: Hernan G. Garcia, Safwat T. Khan, Matthew G. Eason, Roberto A. Chica, Antonia T. Pandelieva, Marc M. Mayer

المصدر: ACS Synth Biol

مصطلحات موضوعية: 0106 biological sciences, Green Fluorescent Proteins, Biomedical Engineering, Biosensing Techniques, Protein Engineering, 01 natural sciences, Biochemistry, Genetics and Molecular Biology (miscellaneous), Rapid detection, Protein expression, Fluorescence, Article, Green fluorescent protein, 03 medical and health sciences, In vivo, 010608 biotechnology, Escherichia coli, 030304 developmental biology, 0303 health sciences, biology, Chemistry, General Medicine, Protein engineering, biology.organism_classification, Cell biology, Biosensor, Bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcdd93afda41a54ffa82d57875b464b
https://pubmed.ncbi.nlm.nih.gov/33044070

المؤلفون: Lin Liu, Michael C. Thompson, Niayesh Zarifi, Erin Nguyen, Aron Broom, Rojo V Rakotoharisoa, Nurzhan Mukhametzhanov, James S. Fraser, Roberto A. Chica

المصدر: Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Evolution, Science, Protein design, General Physics and Astronomy, Lyases, Chemical, Computational biology, Molecular Dynamics Simulation, Crystallography, X-Ray, 010402 general chemistry, Protein Engineering, 01 natural sciences, Article, General Biochemistry, Genetics and Molecular Biology, Catalysis, 03 medical and health sciences, Protein structure, Catalytic Domain, Enzyme Stability, Computer Simulation, Enzyme kinetics, lcsh:Science, Conformational ensembles, X-ray crystallography, Evolution, Chemical, Multidisciplinary, Crystallography, biology, Chemistry, Active site, General Chemistry, Protein engineering, Directed evolution, 0104 chemical sciences, Enzymes, Kinetics, 030104 developmental biology, Mutation, Biocatalysis, biology.protein, X-Ray, lcsh:Q, Directed Molecular Evolution

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d365dfb9700690fb0ebca00b84ea69
https://escholarship.org/uc/item/0z88f0sj

المؤلفون: Antonia T. Pandelieva, Marc M. Mayer, Matthew G. Eason, Roberto A. Chica, Hernan G. Garcia, Safwat T. Khan

مصطلحات موضوعية: In vivo, Chemistry, Fluorescent protein, Biosensor, Fluorescence, Rapid detection, Protein expression, Research model, Green fluorescent protein, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::28b8818459863ded69af2282c80b1be6
https://doi.org/10.1101/2020.07.30.229633

المؤلفون: Michael C. Thompson, Mukhametzhanov N, Erin Nguyen, Lin Liu, Aron Broom, R.V. Rakotoharisoa, James S. Fraser, Roberto A. Chica, Zarifi N

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, biology, Stereochemistry, Chemistry, Protein design, Active site, Crystallographic data, 010402 general chemistry, Directed evolution, 01 natural sciences, 0104 chemical sciences, 03 medical and health sciences, Enzyme, Biocatalysis, biology.protein, Enzyme kinetics, Conformational ensembles, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9f346c2710e9bb37961af65f018731
https://doi.org/10.1101/2020.03.19.999235

المؤلفون: Matthew M Moore, Samuel K Oteng-Pabi, Antonia T Pandelieva, Stephen L Mayo, Roberto A Chica

المصدر: PLoS ONE, Vol 7, Iss 12, p e52463 (2012)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC3527499?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/ee29b0349282447eabd95c4725e1af36

الاتاحة: https://doi.org/10.1371/journal.pone.0052463
https://doaj.org/article/ee29b0349282447eabd95c4725e1af36

المؤلفون: Erin Nguyen, Antonia T. Pandelieva, Roberto A. Chica

المصدر: University of Ottawa Science Undergraduate Research Journal. 1:10-14

مصطلحات موضوعية: Brightness, Chemistry, Mutant, Side chain, Biophysics, Quantum yield, Chromophore, Saturated mutagenesis, mCherry, Fluorescence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::70dfe9eaca9633a600052e4792459c95
https://doi.org/10.18192/osurj.v1i1.3666

المؤلفون: Jean-François Couture, Roberto A. Chica, Curtis J. W. Walton, Frédéric Thiebaut, Joseph S. Brunzelle

المصدر: Biochemistry. 57:5437-5446

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein Conformation, Sequence Homology, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Catalysis, Substrate Specificity, 03 medical and health sciences, Bacterial Proteins, Catalytic Domain, Transferase, Amino Acid Sequence, Amino Acids, Transaminases, Pseudomonas stutzeri, Binding Sites, biology, 010405 organic chemistry, Chemistry, Stereoisomerism, biology.organism_classification, D-phenylglycine aminotransferase, Small molecule, 0104 chemical sciences, 3. Good health, 030104 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1cfe5e344e3e353519453ae45dc34ff
https://doi.org/10.1021/acs.biochem.8b00767

المؤلفون: Benjamin D. Allen, Paul M. Chang, Stephen L. Mayo, Connie Y. Wang, Marie L. Ary, Barry D. Olafson, Roberto A. Chica

المصدر: Protein Science. 27:1113-1124

مصطلحات موضوعية: 0301 basic medicine, Information retrieval, Relational database, Computer science, Database schema, Experimental data, Biochemistry, Visualization, 03 medical and health sciences, Identification (information), 030104 developmental biology, Disparate system, Benchmark (computing), User interface, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2e255e9f4be558b2aa68984e2c8f8a43
https://doi.org/10.1002/pro.3406

المؤلفون: Andrew C Hemmert, Tamara C Otto, Roberto A Chica, Monika Wierdl, Jonathan S Edwards, Steven M Lewis, Carol C Edwards, Lyudmila Tsurkan, C Linn Cadieux, Shane A Kasten, John R Cashman, Stephen L Mayo, Philip M Potter, Douglas M Cerasoli, Matthew R Redinbo

المصدر: PLoS ONE, Vol 6, Iss 3, p e17441 (2011)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC3060870?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/cc3673771a9c4824bb65ae97a1dd1a81

الاتاحة: https://doi.org/10.1371/journal.pone.0017441
https://doaj.org/article/cc3673771a9c4824bb65ae97a1dd1a81