المؤلفون: Avisa Maleki, Elena Crispino, Serena Anna Italia, Valentina Di Salvatore, Maria Assunta Chiacchio, Fianne Sips, Roberta Bursi, Giulia Russo, Davide Maimone, Francesco Pappalardo

المصدر: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3081-3090 (2023)

مصطلحات موضوعية: Multiple sclerosis, Clinical decision support systems, Digital twins, In silico trials, Validation, Modelling and simulation, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037023002027; https://doaj.org/toc/2001-0370

URL الوصول: https://doaj.org/article/ba08fa880ed64faeb056e96e943b35f2

المؤلفون: Fianne L. P. Sips, Francesco Pappalardo, Giulia Russo, Roberta Bursi

المصدر: BMC Medical Informatics and Decision Making, Vol 22, Iss S6, Pp 1-10 (2022)

مصطلحات موضوعية: Relapsing-Remitting Multiple Sclerosis, In silico trials, Digital patient, Computational modeling and simulation, Study design, Computer applications to medicine. Medical informatics, R858-859.7

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1472-6947

URL الوصول: https://doaj.org/article/cae1a307b2ee4a4698c7853fa835de46

المؤلفون: Flora T. Musuamba, Ine Skottheim Rusten, Raphaëlle Lesage, Giulia Russo, Roberta Bursi, Luca Emili, Gaby Wangorsch, Efthymios Manolis, Kristin E. Karlsson, Alexander Kulesza, Eulalie Courcelles, Jean‐Pierre Boissel, Cécile F. Rousseau, Emmanuelle M. Voisin, Rossana Alessandrello, Nuno Curado, Enrico Dall’ara, Blanca Rodriguez, Francesco Pappalardo, Liesbet Geris

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 804-825 (2021)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2163-8306

URL الوصول: https://doaj.org/article/97e2e67f5a5b4314bf9e9f73a5497dde

المؤلفون: Flora T. Musuamba, Roberta Bursi, Efthymios Manolis, Kristin Karlsson, Alexander Kulesza, Eulalie Courcelles, Jean‐Pierre Boissel, Raphaëlle Lesage, Cécile Crozatier, Emmanuelle M. Voisin, Cécile F. Rousseau, Thierry Marchal, Rossana Alessandrello, Liesbet Geris

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 4, Pp 195-197 (2020)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2163-8306

URL الوصول: https://doaj.org/article/8e304d8ae5af4f9299edf6995437c78f

المؤلفون: Chiara, Nicolò, Fianne, Sips, Cristina, Vaghi, Alessia, Baretta, Vincenzo, Carbone, Luca, Emili, Roberta, Bursi

المصدر: Annals of Biomedical Engineering. 51:125-136

مصطلحات موضوعية: Biomedical Engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05094c880a592945628c58555d7d648
https://doi.org/10.1007/s10439-022-03052-6

المؤلفون: Cécile F. Rousseau, Kristin E. Karlsson, Raphaëlle Lesage, Eulalie Courcelles, Emmanuelle M. Voisin, Francesco Pappalardo, Nuno Curado, Enrico Dall'Ara, Flora T. Musuamba, Gaby Wangorsch, Blanca Rodriguez, Ine Skottheim Rusten, Rossana Alessandrello, Roberta Bursi, Giulia Russo, Luca Emili, Efthymios Manolis, Jean-Pierre Boissel, Liesbet Geris, Alexander Kulesza

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 804-825 (2021)
CPT: pharmacometrics & systems pharmacology, 10(8):804-825
CPT: Pharmacometrics & Systems Pharmacology

مصطلحات موضوعية: Computer science, In silico, Building model, White Paper, Context (language use), RM1-950, Risk Assessment, 030226 pharmacology & pharmacy, VIVO, Terminology, 03 medical and health sciences, 0302 clinical medicine, White paper, Drug Development, Terminology as Topic, Credibility, Humans, Computer Simulation, Pharmacology (medical), Pharmacology & Pharmacy, IDENTIFIABILITY ANALYSIS, 030304 developmental biology, 0303 health sciences, Science & Technology, Management science, Models, Theoretical, EFFICACY, Drug development, Modeling and Simulation, SIMULATION, Arzneimittelentwicklung, Therapeutics. Pharmacology, Life Sciences & Biomedicine, MULTISCALE MATHEMATICAL-MODEL, Verification and validation

وصف الملف: application/pdf; Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe3c36e4b9600157dcb89742acab793
https://doaj.org/article/97e2e67f5a5b4314bf9e9f73a5497dde

المؤلفون: Raphaëlle Lesage, Flora T. Musuamba, Thierry Marchal, Cécile Crozatier, Jean-Pierre Boissel, Efthymios Manolis, Eulalie Courcelles, Liesbet Geris, Cécile F. Rousseau, Kristin E. Karlsson, Alexander Kulesza, Rossana Alessandrello, Roberta Bursi, Emmanuelle M. Voisin

المصدر: CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 4, Pp 195-197 (2020)

مصطلحات موضوعية: Pharmacology, Computer science, In silico, Systems Biology, lcsh:RM1-950, MEDLINE, Validation Studies as Topic, Data science, Models, Biological, lcsh:Therapeutics. Pharmacology, Drug development, Drug Development, Modeling and Simulation, Commentary, Humans, Pharmacology (medical), Computer Simulation, Current (fluid), Systems pharmacology, Perspectives

وصف الملف: Print-Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f6e77d14a3d5b9285f9715027488f5
https://lirias.kuleuven.be/handle/123456789/652695

المؤلفون: Marc-Antonio Bisotti, Stefano Severi, Jari Hyttinen, Palazzin Alberto, Michelangelo Paci, Roberta Bursi

المصدر: Journal of Pharmacological and Toxicological Methods. 111:107041

مصطلحات موضوعية: Pharmacology, Drug, business.industry, media_common.quotation_subject, Cancer research, Medicine, Human Induced Pluripotent Stem Cells, Toxicology, business, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e9a04bef2c135287480f0785210a24b6
https://doi.org/10.1016/j.vascn.2021.107041

المؤلفون: Victor Mangas-Sanjuan, José Martín Pastor, Roberta Bursi, Iñaki F. Trocóniz, Jens Rengelshausen

المصدر: British Journal of Clinical Pharmacology. 82:92-107

مصطلحات موضوعية: Pharmacology, education.field_of_study, Chemistry, Metabolite, Analgesic, Population, Cold pressor test, 030226 pharmacology & pharmacy, NONMEM, 03 medical and health sciences, chemistry.chemical_compound, Axomadol, 0302 clinical medicine, Pharmacokinetics, 030202 anesthesiology, Pharmacodynamics, Pharmacology (medical), education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9b1925aa319180dd8e6f8fcf2fcb83a2
https://doi.org/10.1111/bcp.12921

المؤلفون: Dymphy Huntjens, Irmgard Boesl, Chiara Piana, Roberta Bursi, Joachim Grevel

المصدر: European Journal of Drug Metabolism and Pharmacokinetics

مصطلحات موضوعية: Male, Lidocaine, Population, Phases of clinical research, Neuralgia, Postherpetic, Pharmacology, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, Original Research Article, Anesthetics, Local, education, Lead (electronics), Aged, Aged, 80 and over, education.field_of_study, business.industry, Multiple applications, Middle Aged, medicine.disease, Post-herpetic neuralgia, Anesthesia, Neuralgia, Female, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a140457d38920a4cd853b73645a0f31a
https://pubmed.ncbi.nlm.nih.gov/28078530

المؤلفون: Thomas Kerbusch, Jacques Schipper, Mohammed Shahid, Matthew M Hutmacher, Robert Campbell, Roberta Bursi, Kari R. Nations, David Spanswick, Gul Erdemli, Peter Dogterom, Ross Jeggo

المصدر: Psychopharmacology. 218:713-724

مصطلحات موضوعية: Male, Allosteric modulator, AMPA receptor, Pharmacology, Models, Biological, Rats, Sprague-Dawley, Translational Research, Biomedical, Glutamatergic, chemistry.chemical_compound, Allosteric Regulation, Animals, Humans, Computer Simulation, Receptors, AMPA, Receptor, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, PK/PD models, Depressive Disorder, Major, Dose-Response Relationship, Drug, Potentiator, Rats, chemistry, Molecular targets, Org 26576, Psychology, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9680825fd50467ebf8924cf088e112d
https://doi.org/10.1007/s00213-011-2365-6

المؤلفون: Robert A. Campbell, Angus John Morrison, Julia M. Adam, Daniel Ecker, Stuart Francis, James Baker, Anna-Marie Easson, Fiona Jeremiah, Ola Epemolu, Takao Kiyoi, Roberta Bursi, Duncan McArthur, Jurgen Schulz, Darren Edwards, Paul Passier, Maureen Deehan, Paul Westwood, Joanna Udo de Haes, Peter G. Schnabel, Jean E. Cottney, John K. Clark, Glenn Walker, Paul Harradine, Heinz Steinbrede, Paul Ratcliffe, Grant Wishart, Ruth Fields, Jack Pick, Louise Evans

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:2541-2546

مصطلحات موضوعية: Agonist, Indoles, Cannabinoid receptor, Stereochemistry, medicine.drug_class, medicine.medical_treatment, Clinical Biochemistry, hERG, Drug Evaluation, Preclinical, Pharmaceutical Science, Biochemistry, Chemical synthesis, Mice, Structure-Activity Relationship, Dogs, Cytochrome P-450 Enzyme System, Receptor, Cannabinoid, CB1, Heterocyclic Compounds, In vivo, Drug Discovery, medicine, Animals, Rats, Wistar, Molecular Biology, G protein-coupled receptor, biology, Chemistry, Organic Chemistry, Rats, Thiazoles, Drug Design, biology.protein, Molecular Medicine, Cannabinoid, Tail flick test

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac4fce3568bffcc8bec0c8ef27a0ea4
https://doi.org/10.1016/j.bmcl.2011.02.023

المؤلفون: ROBERTA BURSI, PAUL VERWER, AVIV GAZIT, ANDREA R. BECCARI, UCCELLO BARRETTA, GLORIA, BALZANO, FEDERICA, SALVATORE GUCCIONE

المساهمون: H.-D. Höltje, W. Sippl., Roberta, Bursi, Paul, Verwer, Aviv, Gazit, ANDREA R., Beccari, UCCELLO BARRETTA, Gloria, Balzano, Federica, Salvatore, Guccione

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/isbn/84-8124-176-8; info:eu-repo/semantics/altIdentifier/wos/WOS:000169358200027; ispartofbook:Rational approaches to drug design : proceedings of the 13th European Symposium on Quantitative Structure-Activity Relationships, August 27-September 1, 2000, Düsseldorf, Germany; 13th European Symposium on Quantitative Structure-Activity Relationships; firstpage:211; lastpage:213; numberofpages:3; alleditors:H.-D. Höltje, W. Sippl.; http://hdl.handle.net/11568/166151

الاتاحة: http://hdl.handle.net/11568/166151

المؤلفون: Jeroen Kazius, Ross McGuire, Roberta Bursi

المصدر: Journal of Medicinal Chemistry. 48:312-320

مصطلحات موضوعية: Toxicophore, Databases, Factual, Interlaboratory reproducibility, Mutagenicity Tests, Chemistry, fungi, Reproducibility of Results, food and beverages, Models, Theoretical, computer.software_genre, Ames test, Toxicology, Structure-Activity Relationship, Predictive Value of Tests, Drug Discovery, Molecular Medicine, Data mining, computer, Mutagens

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749090dbb967099b0e0e65701fbaad72
https://doi.org/10.1021/jm040835a

المؤلفون: Jos Verhagen, Arijan Grootenhuis, Marcel E. de Gooyer, Jaap van der Louw, Peter L. Jacobs, Dirk Leysen, Roberta Bursi

المصدر: Steroids. 68:213-220

مصطلحات موضوعية: Male, Models, Molecular, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Field analysis, Biochemistry, Catalysis, Steroid, Structure-Activity Relationship, Hydrolysis, Endocrinology, medicine, Humans, Nandrolone, Structure–activity relationship, Molecular Biology, Pharmacology, Human liver, Chemistry, Organic Chemistry, Esters, Prodrug, Microsomes, Liver, Microsome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae73908cabaa9bf679662ad0124813f8
https://doi.org/10.1016/s0039-128x(02)00186-1

المؤلفون: Tiziana Mordasini, Roberta Bursi, Wanda Andreoni, Alessandro Curioni

المصدر: ChemBioChem. 4:155-161

مصطلحات موضوعية: Models, Molecular, Binding Sites, Chemistry, Stereochemistry, Organic Chemistry, Biochemistry, Force field (chemistry), Molecular dynamics, Mutagenesis, Site-Directed, Biophysics, Humans, Molecular Medicine, Computer Simulation, Female, Receptors, Progesterone, Receptor, Molecular Biology, Progesterone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df24dc49b872729fe61c852d3198cf61
https://doi.org/10.1002/cbic.200390026

المؤلفون: Roberta Bursi, Marinus B. Groen

المصدر: European Journal of Medicinal Chemistry. 35:787-796

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Quantitative structure–activity relationship, Crystallography, Hormone Replacement Therapy, Serendipity, Organic Chemistry, Quantitative Structure-Activity Relationship, Quantitative structure, General Medicine, Computational biology, Biology, Endocrinology, Hormonal contraception, Internal medicine, Drug Discovery, Progesterone receptor, medicine, Humans, Structure based, Steroids, Hormone replacement therapy, Progestins, Receptors, Progesterone, Three dimensional model

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd171895e46affc8b79b8d82e110d6c
https://doi.org/10.1016/s0223-5234(00)00168-9

المؤلفون: Peter D. J. Grootenhuis, Roberta Bursi

المصدر: Journal of Computer-Aided Molecular Design. 13:221-232

مصطلحات موضوعية: Computational chemistry, Chemistry, Drug Discovery, Static electricity, Molecule, Interaction energy, Physical and Theoretical Chemistry, Pharmacophore, Electrostatics, Energy minimization, Ligand (biochemistry), Energy (signal processing), Computer Science Applications

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f371dfabb343c16ee7bddc6ad1836718
https://doi.org/10.1023/a:1008010016362

المؤلفون: Vincent F.S. Dubois, Roberta Bursi, Muriel Boulton

المصدر: Journal of Pharmacological and Toxicological Methods. 81:355

مصطلحات موضوعية: Pharmacology, Drug development, business.industry, Pharmacokinetic pharmacodynamic, Bayesian probability, Medicine, Toxicology, business, PK/PD models

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::74c7a6c304ad41f774526fe3bf23792f
https://doi.org/10.1016/j.vascn.2016.02.066

المؤلفون: Jacques Schipper, Allen Lee, Peter Dogterom, Roberta Bursi, Jack Johnstone, Lev Gertsik, Yogesh Pande, Larry Ereshefsky, David Zraket, Gé S.F. Ruigt, Scott Greenwald, Kari R. Nations

المصدر: Journal of psychopharmacology (Oxford, England). 26(12)

مصطلحات موضوعية: Adult, Male, Hydrocortisone, Maximum Tolerated Dose, Placebo-controlled study, Pharmacology, Placebo, Severity of Illness Index, law.invention, chemistry.chemical_compound, Young Adult, Randomized controlled trial, Allosteric Regulation, Double-Blind Method, law, medicine, Humans, Pharmacology (medical), Receptors, AMPA, Adverse effect, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, Psychiatric Status Rating Scales, Depressive Disorder, Major, Dose-Response Relationship, Drug, Human Growth Hormone, Middle Aged, medicine.disease, Antidepressive Agents, Psychiatry and Mental health, Treatment Outcome, Tolerability, chemistry, Pharmacodynamics, Major depressive disorder, Org 26576, Female, Psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045af8691a42f32e63fcabfc395243e5
https://pubmed.ncbi.nlm.nih.gov/22954616