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1Academic Journal
المؤلفون: Kayleigh Walker, Roberta Baravalle, Rachel Holyfield, Jacqueline Kalms, Helena Wright, Chitra Seewooruthun, Frederick W. Muskett, Anthony Scott-Tucker, Andy Merritt, Alistair Henry, Alastair D. G. Lawson, Gareth Hall, Christine Prosser, Mark D. Carr
المصدر: Frontiers in Immunology, Vol 14 (2023)
مصطلحات موضوعية: interleukin-13, single domain antibodies, VHH, receptor signalling, receptor selectivity, allosteric regulation, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
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المؤلفون: Kayleigh Walker, Roberta Baravalle, Rachel Holyfield, Jacqueline Kalms, Helena Wright, Chitra Seewooruthun, Frederick W. Muskett, Anthony Scott-Tucker, Andy Merritt, Alistair Henry, Alastair D. G. Lawson, Gareth Hall, Christine Prosser, Mark D. Carr
مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, interleukin-13, single domain antibodies, VHH, receptor signalling, receptor selectivity, allosteric regulation
الاتاحة: https://doi.org/10.3389/fimmu.2023.1216967.s001
https://figshare.com/articles/dataset/DataSheet_1_Identification_and_characterisation_of_anti-IL-13_inhibitory_single_domain_antibodies_provides_new_insights_into_receptor_selectivity_and_attractive_opportunities_for_drug_discovery_pdf/23635641 -
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المؤلفون: Tara Kang-Pettinger, Kayleigh Walker, Richard Brown, Richard Cowan, Helena Wright, Roberta Baravalle, Lorna C. Waters, Frederick W. Muskett, Matthew W. Bowler, Kovilen Sawmynaden, Peter J. Coombs, Mark D. Carr, Gareth Hall
المصدر: Journal of Biological Chemistry. 299:102769
مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry
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4Academic Journal
المؤلفون: Rebekka Schairer, Gareth Hall, Ming Zhang, Richard Cowan, Roberta Baravalle, Frederick Muskett, Peter Coombs, Chido Mpamhanga, Lisa Hale, Barbara Sixty, Justyna Iwaszkiewicz, Chantal Decaillet, Mai Perroud, Margot Thome, Mark Carr
مصطلحات موضوعية: Uncategorized, Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, protease, structure, ubiquitin, signaling, T cell, NF-KAPPA-B, T-CELL, PARACASPASE MALT1, LYMPHOMA, INHIBITORS, MONOUBIQUITINATION, IDENTIFICATION, INACTIVATION, RESPONSES
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5
المؤلفون: Gianfranco Gilardi, Gianluca Catucci, Roberta Baravalle, Piero Ugliengo, Giuseppe Cimicata, Alberto Ciaramella, Valentina Dell'Angelo, Giovanna Di Nardo
المصدر: Biotechnology and Applied Biochemistry. 65:46-53
مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Conformational change, biology, Stereochemistry, Process Chemistry and Technology, Biomedical Engineering, Active site, Substrate (chemistry), Bioengineering, General Medicine, Ligand (biochemistry), Applied Microbiology and Biotechnology, 03 medical and health sciences, 030104 developmental biology, Enzyme, Protein structure, chemistry, Drug Discovery, biology.protein, Molecular Medicine, Aromatase, Lipid bilayer, Biotechnology
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6
المؤلفون: Sheila J. Sadeghi, Silvia Castrignanò, Giovanna Di Nardo, Gianfranco Gilardi, Roberta Baravalle
المصدر: Electrochemistry Communications, Vol 52, Iss, Pp 25-28 (2015)
مصطلحات موضوعية: aromatase, medicine.medical_specialty, biology, medicine.drug_class, Chemistry, bioelectrochemistry, Aromatization, Cytochrome P450, Glassy carbon, oestrogen, Catalysis, Enzyme catalysis, lcsh:Chemistry, lcsh:Industrial electrochemistry, lcsh:QD1-999, Estrogen, Bioelectrochemistry, Electrochemistry, medicine, biology.protein, Organic chemistry, Aromatase, lcsh:TP250-261
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7
المؤلفون: Roberta Baravalle, Gianfranco Gilardi, Francesca Baj, Alberto Ciaramella, Giovanna Di Nardo
مصطلحات موضوعية: 0301 basic medicine, Bisphenol A, Alkali assay, Endocrine disrupting chemicals, Human aromatase, Analytical Chemistry, Biophysics, Biochemistry, Molecular Biology, Gene Expression, Endocrine Disruptors, 010501 environmental sciences, Pharmacology, Ligands, 01 natural sciences, chemistry.chemical_compound, Stilbenes, Aromatase, chemistry.chemical_classification, biology, Aromatase Inhibitors, Recombinant Proteins, Ketoconazole, Biological Assay, Protein Binding, Nicotine, Estrone, Enzyme-Linked Immunosorbent Assay, Anastrozole, Sildenafil Citrate, Small Molecule Libraries, 03 medical and health sciences, Phenols, Nitriles, Humans, Endocrine system, Benzhydryl compounds, Benzhydryl Compounds, 0105 earth and related environmental sciences, Cytochrome P450, Triazoles, 030104 developmental biology, Enzyme, chemistry, Resveratrol, biology.protein, NADP, Hormone
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8
المؤلفون: Ines Barone, Gianfranco Gilardi, Stefania Catalano, Sebastiano Andò, Giovanna Di Nardo, Roberta Baravalle, Andrea Bandino
مصطلحات موضوعية: 0301 basic medicine, Endocrinology, Diabetes and Metabolism, Amino Acid Motifs, Clinical Biochemistry, Molecular Conformation, Biochemistry, Human aromatase, Endocrinology, Aromatase, Phosphorylation, Neurons, chemistry.chemical_classification, biology, Kinase, Circular Dichroism, MCF-7 breast cancer cells, SNPs, ST14A neuronal cells, Recombinant Proteins, MCF-7 Cells, Molecular Medicine, Female, medicine.medical_specialty, medicine.drug_class, Breast Neoplasms, Catalysis, Cell Line, 03 medical and health sciences, Internal medicine, Cyclic GMP-Dependent Protein Kinases, medicine, Animals, Humans, Molecular Biology, Polymorphism, Genetic, Wild type, Cytochrome P450, Estrogens, Cell Biology, Cyclic AMP-Dependent Protein Kinases, Coculture Techniques, Rats, 030104 developmental biology, Enzyme, chemistry, Estrogen, Cell culture, Mutation, Mutagenesis, Site-Directed, biology.protein, Spectrophotometry, Ultraviolet
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9
المؤلفون: Giovanna Di Nardo, Francesca Valetti, Mario Chiesa, Giovanna Gambarotta, Roberta Baravalle, Gianfranco Gilardi, Sebastiano Andò, Gianluca Catucci, Sara Maurelli, Stefania Catalano, Ines Barone, Elio Giamello
المصدر: The Journal of steroid biochemistry and molecular biology. 165
مصطلحات موضوعية: 0301 basic medicine, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Pharmacology, Ligands, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Breast cancer, Aromatase, chemistry.chemical_classification, biology, Chemistry, Aromatase Inhibitors, Recombinant Proteins, Molecular Docking Simulation, Spectrophotometry, 030220 oncology & carcinogenesis, MCF-7 Cells, Molecular Medicine, Female, Two-dimensional nuclear magnetic resonance spectroscopy, Cytochromes P450, Protein Binding, Sildenafil, Iron, Kinetics, Breast Neoplasms, Heme, Catalysis, Sildenafil Citrate, 03 medical and health sciences, Inhibitory Concentration 50, medicine, Humans, Molecular Biology, Cyclic Nucleotide Phosphodiesterases, Type 5, Dose-Response Relationship, Drug, Electron Spin Resonance Spectroscopy, Water, Estrogens, Cell Biology, medicine.disease, In vitro, 030104 developmental biology, Enzyme, Docking (molecular), Aromatase inhibitors, biology.protein, Spectrophotometry, Ultraviolet
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