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المؤلفون: Li Ma, Robert C.C. Mercer, Robert Strome, Gerold Schmitt-Ulms, Serene Wohlgemuth, Michael B. Coulthart, Jack H. Jhamandas, David Westaway, Neil R. Cashman, Joel C. Watts, Jing Yang
المصدر: Journal of Biological Chemistry. 288:37241-37255
مصطلحات موضوعية: endocrine system, Potassium Channels, endocrine system diseases, animal diseases, Nerve Tissue Proteins, Biology, Biochemistry, Membrane Potentials, Cell membrane, Amyloid beta-Protein Precursor, Mice, Prosencephalon, medicine, Animals, Humans, PrPC Proteins, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Molecular Biology, Neurons, Membrane potential, Basal forebrain, digestive, oral, and skin physiology, Cell Membrane, HEK 293 cells, Wild type, Cell Biology, Molecular biology, Mice, Mutant Strains, Potassium channel, nervous system diseases, Cell biology, HEK293 Cells, Shal Potassium Channels, medicine.anatomical_structure, Membrane protein, Mutation, Cholinergic
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المؤلفون: S D’Amelio, Christopher Janus, George A. Carlson, Paul E. Fraser, O Amitay, John C. Roder, Robert Strome, P H St George Hyslop, David Westaway, M A Chishti
المصدر: Neurobiology of Aging. 21:541-549
مصطلحات موضوعية: Genetically modified mouse, Aging, Genotype, Transgene, Mutant, Gene Expression, Morris water navigation task, Mice, Transgenic, medicine.disease_cause, Presenilin, Discrimination Learning, Mice, Cognition, Alzheimer Disease, Presenilin-1, medicine, Animals, Humans, Longitudinal Studies, Transgenes, Allele, Maze Learning, Swimming, Mutation, General Neuroscience, Wild type, Membrane Proteins, Molecular biology, Mice, Inbred C57BL, Disease Models, Animal, Space Perception, Exploratory Behavior, Neurology (clinical), Geriatrics and Gerontology, Psychology, Neuroscience, Developmental Biology
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المؤلفون: Ling-Hong Hung, Henry M. Krause, Robert Strome, Jianli Dong
المصدر: The EMBO Journal. 17:2308-2318
مصطلحات موضوعية: Threonine, Transcription, Genetic, Fushi Tarazu Transcription Factors, Wnt1 Protein, Biology, General Biochemistry, Genetics and Molecular Biology, Cell Line, Animals, Genetically Modified, Structure-Activity Relationship, Proto-Oncogene Proteins, Animals, Drosophila Proteins, Homeostasis, Phosphorylation, Binding site, Protein kinase A, Molecular Biology, Homeodomain Proteins, Aspartic Acid, Alanine, Binding Sites, General Immunology and Microbiology, Schneider 2 cells, General Neuroscience, fungi, DNA, Cyclic AMP-Dependent Protein Kinases, Biochemistry, Mutagenesis, Site-Directed, Homeobox, Drosophila, Signal transduction, Drosophila Protein, Research Article, Transcription Factors
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المؤلفون: Robert Strome, George A. Carlson, David Westaway, M. Azhar Chishti
المصدر: Neuroscience Letters. 234:11-14
مصطلحات موضوعية: Gene isoform, Prions, animal diseases, Population, Hamster, Mice, Transgenic, Scrapie, Epitope, Mice, Cricetinae, medicine, Animals, Photoreceptor Cells, education, education.field_of_study, Retina, Mesocricetus, biology, General Neuroscience, biology.organism_classification, Virology, nervous system diseases, Cell biology, medicine.anatomical_structure, sense organs, Immunostaining
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المؤلفون: Weiming Xia, Ivan Lieberburg, Peter St. George Hyslop, Dale Schenk, G. Levesque, Thekla S. Diehl, Peter Seubert, Dennis J. Selkoe, Paul E. Fraser, Billie J. Perry, Dora Kholodenko, Kelly Johnson-Wood, Robert Strome, Johanna M. Rommens, Soyeon Kim, Hong Yao, Angela Davis, Ruth Motter, Martin Citron, R. Sherrington, George A. Carlson, David Westaway, Michael K. Lee
المصدر: Nature Medicine. 3:67-72
مصطلحات موضوعية: Genetically modified mouse, Amyloid, Genetic Vectors, Mutant, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Biology, Transfection, medicine.disease_cause, Hippocampus, General Biochemistry, Genetics and Molecular Biology, Presenilin, Cell Line, Amyloid beta-Protein Precursor, Mice, Alzheimer Disease, Presenilin-2, mental disorders, Presenilin-1, medicine, Animals, Humans, APH-1, Mutation, Amyloid beta-Peptides, Wild type, Brain, Membrane Proteins, General Medicine, medicine.disease, Molecular biology, Peptide Fragments, Alzheimer's disease
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المؤلفون: Robert Strome, Hansen Wang, Lili-Naz Hazrati, George A. Carlson, Hairu Huo, Sepehr Ehsani, Ekaterina Rogaeva, Gerold Schmitt-Ulms, Kelvin So, Cosmin L. Pocanschi, William S. Trimble, Mohadeseh Mehrabian, David Westaway, William Reginold, Christine Sato, Hezhen Ren, Ashkan Salehzadeh
المصدر: Journal of molecular biology. 422(4)
مصطلحات موضوعية: Glycosylation, Cations, Divalent, Prions, Proteolysis, animal diseases, Molecular Sequence Data, Biology, Article, Prion Diseases, 03 medical and health sciences, Mice, 0302 clinical medicine, Protein structure, Structural Biology, Cell Line, Tumor, medicine, Extracellular, Transition Elements, Animals, Amino Acid Sequence, Molecular Biology, Gene, Peptide sequence, Cation Transport Proteins, 030304 developmental biology, 0303 health sciences, medicine.diagnostic_test, Cell Membrane, Membrane Proteins, nervous system diseases, Protein Structure, Tertiary, Transmembrane domain, Zinc, Biochemistry, Ectodomain, Cell culture, Metals, Carrier Proteins, Protein Processing, Post-Translational, 030217 neurology & neurosurgery
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المؤلفون: Christine Sato, Danielle Moreno, Janice Robertson, Juan M. Bilbao, Robert Strome, Ekaterina Rogaeva, Lorne Zinman, Shinya Tokuhiro, Lili-Naz Hazrati, Ian R. A. Mackenzie
المصدر: Neurobiology of aging. 32(3)
مصطلحات موضوعية: Male, Aging, Cytoplasmic inclusion, DNA Mutational Analysis, Biology, Exon, Asian People, medicine, Humans, Point Mutation, Amyotrophic lateral sclerosis, Gene, General Neuroscience, Amyotrophic Lateral Sclerosis, Motor Cortex, Middle Aged, medicine.disease, Cancer research, Mutation testing, Immunohistochemistry, RNA-Binding Protein FUS, Neurology (clinical), Brainstem, Geriatrics and Gerontology, Immunostaining, Developmental Biology, Brain Stem
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المؤلفون: Charlie Boone, David Westaway, Dilya Arslanova, Robert Strome, Matthew J. Mazzella, Peter Mastrangelo, Paul E. Fraser, Paul M. Mathews, Peter St George-Hyslop
المصدر: Alzheimer's & Dementia. 2
مصطلحات موضوعية: biology, Epidemiology, Chemistry, Health Policy, Nicastrin, Presenilin, Yeast, Cell biology, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, biology.protein, Neurology (clinical), Geriatrics and Gerontology, Gamma secretase
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المؤلفون: Céline Morissette, Patrick Horne, George A. Carlson, Sherry Turner, Christopher Janus, Noah Zuker, Peter St George-Hyslop, David Westaway, Jacqueline Pearson, Paul E. Fraser, Amie L. Phinney, Dun-Shen Yang, Gianluca Lozza, Francine Gervais, Janet French, Suzanne Kunicki, Robert Strome, Mariagrazia Grilli, Catherine Bergeron, M. Azhar Chishti, Julie Paquette, James E. Loukides
المصدر: The Journal of biological chemistry. 276(24)
مصطلحات موضوعية: Genetically modified mouse, Male, medicine.medical_specialty, Aging, Amyloid, Transgene, BACE1-AS, Restriction Mapping, Morris water navigation task, Mice, Transgenic, Biochemistry, Presenilin, Amyloid beta-Protein Precursor, Mice, Internal medicine, Amyloid precursor protein, medicine, Animals, Humans, Maze Learning, Promoter Regions, Genetic, Molecular Biology, Crosses, Genetic, Mice, Inbred C3H, biology, Brain, Cell Biology, Amyloidosis, Biochemistry of Alzheimer's disease, Mice, Inbred C57BL, Endocrinology, Amino Acid Substitution, biology.protein, Mutagenesis, Site-Directed, Female, Cognition Disorders
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المؤلفون: Catherine Bergeron, R. Sherrington, George A. Carlson, P. St. George-Hyslop, David Westaway, G. Levesque, C. Weaver, John C. Roder, Sam Gandy, Paul E. Fraser, Robert Strome, Johanna M. Rommens, Hong Yao, D. Shenk, B. Perry, Peter Davies, A. Davies
المصدر: Prions and Brain Diseases in Animals and Humans ISBN: 9781489918987
مصطلحات موضوعية: Genetics, Amyloid, Point mutation, mental disorders, Neurodegeneration, medicine, Neurofibrillary tangle, Cerebral amyloid angiopathy, Alzheimer's disease, Biology, medicine.disease, Gene, Presenilin
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المؤلفون: Robert Borst, Robert Strome
المصدر: Astrodynamics Conference.
مصطلحات موضوعية: Engineering, business.industry, Flutter, Structural engineering, business
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المؤلفون: Robert Strome, Stephen D. Schmidt, P. St. George-Hyslop, George A. Carlson, M. Mezzella, Ralph A. Nixon, David Westaway, Christine Ebeling, Muhammad A. Chishti, Evgeny I. Rogaev, E.J. Yang, Peter Mastrangelo, Paul M. Mathews, Marc Mercken, Richard Rozmahel, Ying Jiang, Paul D. Fraser
المصدر: Neurobiology of Aging. 25:S252
مصطلحات موضوعية: Aging, biology, Chemistry, General Neuroscience, biology.protein, Neurology (clinical), Geriatrics and Gerontology, Amyloid precursor protein secretase, Developmental Biology, Cell biology
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المؤلفون: Joel C. Watts, Jing Yang, Robert Strome, Howard T.J. Mount, Peter Mastrangelo, Janaky Coomaraswamy, David Westaway, Bettina Drisaldi
المصدر: Neurobiology of Aging. 25:S413
مصطلحات موضوعية: Aging, General Neuroscience, Neurology (clinical), Geriatrics and Gerontology, Biology, Molecular biology, Cell culture assays, Developmental Biology
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المصدر: Neurobiology of Aging. 21:68
مصطلحات موضوعية: Aging, Chemistry, General Neuroscience, Neurology (clinical), γ secretase, Geriatrics and Gerontology, Yeast, Presenilin, Developmental Biology, Cell biology
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المؤلفون: David Westaway, M.Azhar Chrishti, Patrick Horne, George A. Carlson, Donna Haskin, Catherine Bergeron, Dun-Sheng Yang, Robert Strome
المصدر: Neurobiology of Aging. 21:126
مصطلحات موضوعية: Aging, biology, Chemistry, General Neuroscience, Transgene, BACE1-AS, Mutant, P3 peptide, Molecular biology, Biochemistry of Alzheimer's disease, biology.protein, Amyloid precursor protein, Neurology (clinical), Geriatrics and Gerontology, Amyloid precursor protein secretase, Developmental Biology, Early onset
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المؤلفون: David Westaway, George A. Carlson, Robert Strome, Gang Yu, Azhar M. Chishti, Paul M. Mathews, Fusheng Chen, Richard Rozmahel
المصدر: Neurobiology of Aging. 21:133
مصطلحات موضوعية: Genetics, Aging, General Neuroscience, biology.protein, Neurology (clinical), Geriatrics and Gerontology, Allele, Biology, Amyloid precursor protein secretase, Developmental Biology
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المؤلفون: Robert Strome, Hong Yao, David Westaway, Paul E. Fraser, Gregory L. Silverman, J. L. Laplanche, P. St. George-Hyslop, J. F. Foncin
المصدر: Journal of Neuropathology and Experimental Neurology. 56:596
مصطلحات موضوعية: Cellular and Molecular Neuroscience, Neurology, Terminal (electronics), Chemistry, Mutant, Wild type, Neurology (clinical), General Medicine, Pathology and Forensic Medicine, Cell biology
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المؤلفون: Kefeng Qin, Axel Madlung, Hans A. Kretzschmar, David Westaway, David R. Brown, T. P. A. Kruck, A von Bohlen, Jean Manson, Paul E. Fraser, Jochen Herms, Walter J. Schulz-Schaeffer, Armin Giese, Robert Strome
المصدر: ResearcherID
مصطلحات موضوعية: animal diseases, Scrapie, Plasma protein binding, In Vitro Techniques, Kidney, Superoxide dismutase, 03 medical and health sciences, Mice, Purkinje Cells, 0302 clinical medicine, Cerebellum, mental disorders, Metalloprotein, Animals, Humans, PrPC Proteins, Binding site, Cells, Cultured, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Multidisciplinary, biology, Muscles, Kidney metabolism, Cooperative binding, Brain, nervous system diseases, Electrophysiology, Mice, Inbred C57BL, Biochemistry, chemistry, Liver, Glycine, Synapses, biology.protein, 030217 neurology & neurosurgery, Copper, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b31d6a7ee3c8b22fab9b6854eb454e2
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997YM50800031&KeyUID=WOS:A1997YM50800031 -
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المؤلفون: Robert Strome, George A. Carlson, David Westaway, Patrick Tremblay, Gregory L. Silverman, Richard C. Moore, Fred E. Cohen, Paul M. Harrison, Stanley B. Prusiner, Leroy Hood, Stephen H. Pasternak, A. Karunaratne, Kai Wang, Inyoul Lee, M A Chishti, D. W. Melton, Yan Liang, Cornelia Heinrich, Peter Mastrangelo, S. Katamine, Arian Fa Smit
المصدر: ResearcherID
Stephen H. Pasternakمصطلحات موضوعية: Central Nervous System, Male, Glycosylation, Prions, animal diseases, Transgene, Amino Acid Motifs, Molecular Sequence Data, Mice, Transgenic, Biology, GPI-Linked Proteins, PRNP, Cell Line, Trans-Splicing, Mice, Purkinje Cells, Downregulation and upregulation, Structural Biology, medicine, Animals, Amino Acid Sequence, RNA, Messenger, Cloning, Molecular, Molecular Biology, Gene, Peptide sequence, Messenger RNA, Mice, Inbred BALB C, Base Sequence, Neurodegeneration, medicine.disease, Embryo, Mammalian, Molecular biology, nervous system diseases, Up-Regulation, RNA splicing, Ataxia, Sequence Alignment, Gene Deletion
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce2547c1d1b9f2a7b5fff3ba8defb48
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000083134500005&KeyUID=WOS:000083134500005