المؤلفون: Karsten Suhre, Matthias Arnold, Aditya Mukund Bhagwat, Richard J. Cotton, Rudolf Engelke, Johannes Raffler, Hina Sarwath, Gaurav Thareja, Annika Wahl, Robert Kirk DeLisle, Larry Gold, Marija Pezer, Gordan Lauc, Mohammed A. El-Din Selim, Dennis O. Mook-Kanamori, Eman K. Al-Dous, Yasmin A. Mohamoud, Joel Malek, Konstantin Strauch, Harald Grallert, Annette Peters, Gabi Kastenmüller, Christian Gieger, Johannes Graumann

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/8795d9d74e404676970c345596c0741f

المؤلفون: Karsten Suhre, Matthias Arnold, Aditya Mukund Bhagwat, Richard J. Cotton, Rudolf Engelke, Johannes Raffler, Hina Sarwath, Gaurav Thareja, Annika Wahl, Robert Kirk DeLisle, Larry Gold, Marija Pezer, Gordan Lauc, Mohammed A. El-Din Selim, Dennis O. Mook-Kanamori, Eman K. Al-Dous, Yasmin A. Mohamoud, Joel Malek, Konstantin Strauch, Harald Grallert, Annette Peters, Gabi Kastenmüller, Christian Gieger, Johannes Graumann

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c1e1c89ac28d4d7f99eabe2e099433bd

المؤلفون: Xavier C. Ding, Ewurama D. A. Owusu, Robert Kirk DeLisle, Seda Yerlikaya, Augustina Frimpong

المصدر: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

مصطلحات موضوعية: Microbiology (medical), Plasmodium falciparum, malaria, Protozoan Proteins, Antigens, Protozoan, Computational biology, Proteomics, Sensitivity and Specificity, World health, Uncomplicated malaria, parasitic diseases, Major Article, diagnostics, Global health, medicine, Humans, Diagnostic biomarker, Malaria, Falciparum, Rapid diagnostic test, GAPDH, DHFR-TS, Diagnostic Tests, Routine, business.industry, medicine.disease, Biomarker (cell), AcademicSubjects/MED00290, Infectious Diseases, biomarker, business, Biomarkers, Malaria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59c41faea527a1dbb9813b7ddf296eb
https://doi.org/10.1093/cid/ciab251

المؤلفون: Tim Bauer, Martin J. Shipley, Mark A. Sarzynski, Leigh Alexander, Yolanda Hagar, Michael A Hinterberg, Aroon D. Hingorani, Stephen A. Williams, Mika Kivimäki, Juan P. Casas, Sophie Weiss, Christian Jonasson, Claudia Langenberg, Nicholas J. Wareham, Rachel Ostroff, Peter Ganz, Gargi Datta, Jessica Chadwick, Jessica A. Ash, Robert Kirk DeLisle, Claude Bouchard

المصدر: Nat Med
Nature medicine, vol 25, iss 12
Nature Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, Diabetes risk, Immunology, Disease, Intra-Abdominal Fat, Cardiovascular, Bioinformatics, Medical and Health Sciences, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Behavioral and Social Science, Health care, Humans, Medicine, Obesity, Precision Medicine, Exercise, Life Style, Metabolic and endocrine, Nutrition, business.industry, Prevention, Blood Proteins, General Medicine, Precision medicine, Blood proteins, Health indicator, Heart Disease, Good Health and Well Being, 030104 developmental biology, Adipose Tissue, Liver, Health assessment, 030220 oncology & carcinogenesis, Body Composition, Lean body mass, Female, Generic health relevance, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3c9c49c93d371832bfa7eddf14f5d6
https://doi.org/10.1038/s41591-019-0665-2

المؤلفون: Joseph Yang, Sophie Weiss, Edward N. Brody, Stephen A. Williams, Ashwin C. Murthy, Robert Kirk DeLisle, Robert Mehler, Rachel Ostroff, Peter Ganz

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

مصطلحات موضوعية: Male, Proteome, Renal function, Coronary Disease, 030204 cardiovascular system & hematology, Proteomics, Bioinformatics, Cohort Studies, outcomes research, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, In patient, 030212 general & internal medicine, Renal Insufficiency, Chronic, Aged, Original Research, business.industry, Editorials, Middle Aged, medicine.disease, Coronary heart disease, Editorial, Heart Disease Risk Factors, Female, Cardiology and Cardiovascular Medicine, business, Biomarkers, chronic kidney disease, coronary artery disease, Kidney disease, Glomerular Filtration Rate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342ab21646d4cab695f9a7330a36d32e
https://pubmed.ncbi.nlm.nih.gov/32696700

المؤلفون: Craig L. Hyde, Rachel Ostroff, Peter Ganz, Stephen A. Williams, Robert Kirk DeLisle, Mark R. Segal, Ashwin C. Murthy, Anders Mälarstig, Sophie Weiss

المصدر: Circulation, vol 137, iss 10

مصطلحات موضوعية: Proteomics, Male, Aging, Myocardial Infarction, 030204 cardiovascular system & hematology, Cardiorespiratory Medicine and Haematology, Cardiovascular, Bioinformatics, chemistry.chemical_compound, 0302 clinical medicine, Medicine, 030212 general & internal medicine, Prospective Studies, Aldosterone, media_common, Anticholesteremic Agents, Middle Aged, Prognosis, 3. Good health, Stroke, Heart Disease, Drug development, Quinolines, Public Health and Health Services, Female, Patient Safety, Cardiology and Cardiovascular Medicine, Drug, Drug-Related Side Effects and Adverse Reactions, media_common.quotation_subject, precision medicine, prescription drugs, Clinical Sciences, aptamers, Early detection, 03 medical and health sciences, Clinical Research, Physiology (medical), Humans, Adverse effect, Aged, Heart Failure, business.industry, Prevention, Pharmacological, Torcetrapib, biomarkers, Precision medicine, Survival Analysis, proteins, Cholesterol Ester Transfer Proteins, Good Health and Well Being, Early Diagnosis, chemistry, Cardiovascular System & Hematology, Case-Control Studies, peptides, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649d303bf8aaab84972f48df7f2ff28b
https://escholarship.org/uc/item/6593b5zh

المؤلفون: Sally K. Nelson, Yetrib Hathout, Bob Mehler, Heather Gordish-Dressman, Linda H. Cripe, Edward N. Brody, Angela Lorts, Malti Nikrad, H. Lee Sweeney, Craig M. McDonald, Robert Kirk DeLisle, Paula R. Clemens, Yvonne M. Kobayashi, Erik K Henricson, Steve C.R. Williams, Pat Furlong, Fintan Steele, Jean K. Mah, Lauren P. Hache, Eric P. Hoffman, Larry Gold, Britta Singer, David Sterling

المصدر: Proceedings of the National Academy of Sciences. 112:7153-7158

مصطلحات موضوعية: Adult, Male, musculoskeletal diseases, Oncology, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Pathology, Adolescent, Duchenne muscular dystrophy, Serum protein, Disease pathogenesis, Proteomics, Cohort Studies, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Humans, Medicine, Biomarker discovery, Child, 030304 developmental biology, 0303 health sciences, Multidisciplinary, business.industry, Surrogate endpoint, Blood Proteins, Biological Sciences, medicine.disease, 3. Good health, Muscular Dystrophy, Duchenne, Case-Control Studies, Child, Preschool, Cohort, business, Biomarkers, 030217 neurology & neurosurgery, Natural history study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb8504683f7bfed720b6e16aea45b2a
https://doi.org/10.1073/pnas.1507719112

المؤلفون: Darin Smith, Guy Vigers, Sumeet Rana, Michael Burkard, April Cox, Robert D. Groneberg, Ryan J. Watts, Robert Kirk Delisle, Tony Pisal Tang, Andrew T. Metcalf, Kelly Regal, Susan P. Rhodes, Mary K. Geck Do, Karin D. Brown, Joseph P. Lyssikatos, Douglas Mccord Sammond, Matthew Volgraf, Albion D. Wright, Gunawardana Indrani W, Kimberly Scearce-Levie, Jennifer N. Otten, Allen A. Thomas, Michael Siu, Hans E. Purkey, Kevin W. Hunt, Xingrong Liu, Darrin Dutcher

المصدر: Journal of Medicinal Chemistry. 57:878-902

مصطلحات موضوعية: Male, Models, Molecular, Stereochemistry, Guinea Pigs, Cathepsin D, Stereoisomerism, CHO Cells, Crystallography, X-Ray, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Cricetulus, Cell Line, Tumor, Cricetinae, Drug Discovery, Amyloid precursor protein, Animals, Aspartic Acid Endopeptidases, Humans, Moiety, Structure–activity relationship, Spiro Compounds, Chromans, Guanidine, Pyrans, chemistry.chemical_classification, Amyloid beta-Peptides, biology, Brain, Rats, Macaca fascicularis, HEK293 Cells, Enzyme, chemistry, Biochemistry, biology.protein, Molecular Medicine, Efflux, Amyloid Precursor Protein Secretases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936cb574f0793c10f3925c44b16b4302
https://doi.org/10.1021/jm401635n

المؤلفون: Yasmin A. Mohamoud, Richard Cotton, Marija Pezer, Hina Sarwath, Gordan Lauc, Joel A. Malek, Harald Grallert, Dennis O. Mook-Kanamori, Eman K. Al-Dous, Johannes Raffler, Johannes Graumann, Gabi Kastenmüller, Annika Wahl, Mohammed A. El-Din Selim, Karsten Suhre, Rudolf Engelke, Robert Kirk DeLisle, Matthias Arnold, Konstantin Strauch, Annette Peters, Christian Gieger, Gaurav Thareja, Larry Gold, Aditya M. Bhagwat

المصدر: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications, 8
Nat. Commun. 8:14357 (2017)

مصطلحات موضوعية: 0301 basic medicine, Genetics, medicine.medical_specialty, Multidisciplinary, Science, Gene regulatory network, GWAS, genetic risk, disease, plasma, proteome, General Physics and Astronomy, Genome-wide association study, General Chemistry, Disease, Computational biology, Quantitative trait locus, Biology, Proteomics, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 030104 developmental biology, Molecular genetics, medicine, Allele, Genetic association

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e0ac4553981a2870f42942d95ae5a9
https://hdl.handle.net/1887/115579

المؤلفون: Hina Sarwath, Harald Grallert, Marija Pezer, Johannes Raffler, Dennis O. Mook-Kanamori, Mohammed A. El-Din Selim, Yasmin A. Mohamoud, Aditya M. Bhagwat, Larry Gold, Eman K. Al-Dous, Joel A. Malek, Robert Kirk DeLisle, Richard Cotton, Annika Laser, Johannes Graumann, Karsten Suhre, Rudolf Engelke, Christian Gieger, Gaurav Thareja, Matthias Arnold, Konstantin Strauch, Annette Peters, Gabi Kastenmüller, Gordan Lauc

مصطلحات موضوعية: Proteome, Cohort, Genome-wide association study, Disease, Computational biology, Biology, Proteomics, Gene, Phenotype, Genetic association

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbd6d4d49ecc257e47a47e1975a3dc3
https://doi.org/10.1101/086793

المؤلفون: Daniel C. Weaver, Manuel Laguna, Robert Kirk DeLisle, Michele Samorani

المصدر: INFORMS Journal on Computing. 23:331-345

مصطلحات موضوعية: Process (engineering), Computer science, business.industry, General Engineering, Statistical relational learning, Sample (statistics), Machine learning, computer.software_genre, Set (abstract data type), Knowledge extraction, Artificial intelligence, Data mining, Representation (mathematics), business, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::64e21ecade0dcf8ed3c341cc7050753a
https://doi.org/10.1287/ijoc.1100.0404

المؤلفون: Robert Kirk DeLisle

المصدر: Current Computer Aided-Drug Design. 5:139-144

مصطلحات موضوعية: Drug Discovery, Molecular Medicine, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b17e15bb630edf3ffd3214fb97c80650
https://doi.org/10.2174/157340909788451900

المؤلفون: Andrei Victor Anghelescu, Xiaoming Xie, Anthony E. Klon, Robert Kirk DeLisle, Jeffrey F. Lowrie, David J. Diller

المصدر: Journal of Chemical Information and Modeling. 48:1041-1054

مصطلحات موضوعية: Receptors, CXCR3, biology, Stereochemistry, Chemistry, General Chemical Engineering, hERG, Molecular Conformation, General Chemistry, Library and Information Sciences, Lower dimensional space, Ligands, Estrogen Receptor Agonists, Computer Science Applications, Estrogen Receptor Antagonists, Receptors, Estrogen, Potassium Channel Blockers, biology.protein, Biological system, Algorithms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488eb52849aff987dfae89483a8573af
https://doi.org/10.1021/ci700395f

المؤلفون: Robert Kirk DeLisle, Mathew Merkow

المصدر: Journal of Chemical Information and Modeling. 47:1797-1807

مصطلحات موضوعية: Self-organizing map, Theoretical computer science, General Chemical Engineering, Computer Science::Neural and Evolutionary Computation, Molecular Conformation, Normal Distribution, Library and Information Sciences, Network topology, Structure-Activity Relationship, Planar, Artificial Intelligence, Cluster Analysis, Cluster analysis, Mathematics, Pharmacology, Artificial neural network, business.industry, Quantization (signal processing), Computational Biology, Pattern recognition, General Chemistry, Grid, Computer Science Applications, Visualization, ComputingMethodologies_PATTERNRECOGNITION, Databases as Topic, Neural Networks, Computer, Artificial intelligence, business, Algorithms, Software

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb4b214aabfd9967297ff152cbac3a4
https://doi.org/10.1021/ci7001445

المؤلفون: Robert Kirk DeLisle, Jeffery F. Lowrie, Doug W. Hobbs, David J. Diller

المصدر: Current Computer Aided-Drug Design. 1:325-345

مصطلحات موضوعية: Drug, Computational model, Philosophy of design, business.industry, Computer science, media_common.quotation_subject, General Medicine, medicine.disease, Toxicology, Resource (project management), Drug development, Risk analysis (engineering), Drug Discovery, medicine, Molecular Medicine, Attrition, business, Pharmaceutical industry, ADME, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::70830ea64c3772d9580bc597cbd2340b
https://doi.org/10.2174/157340905774330309

المؤلفون: Robert Kirk Delisle, David J. Diller, Norman Wang

المصدر: Journal of Medicinal Chemistry. 48:6980-6990

مصطلحات موضوعية: Models, Molecular, Databases, Factual, Protein family, Quantitative Structure-Activity Relationship, Sequence alignment, Computational biology, Ligands, Drug Discovery, Catalytic triad, Humans, Alignment-free sequence analysis, Genetics, Multiple sequence alignment, Molecular Structure, Sequence Homology, Amino Acid, Chemistry, Computational Biology, Small molecule, Ether-A-Go-Go Potassium Channels, Similitude, Transmembrane domain, src-Family Kinases, Mutation, Molecular Medicine, Sequence Alignment, Algorithms, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e7edb5614e7ec3c67a1144a8ad939a2
https://doi.org/10.1021/jm050563r

المؤلفون: William J. Welsh, Stefan Paula, Susan M. Keenan, Robert Kirk Delisle, William J. Ball

المصدر: Journal of Molecular Graphics and Modelling. 23:465-475

مصطلحات موضوعية: Digoxin, Cardiotonic Agents, Protein Conformation, ATPase, Molecular Sequence Data, Drug design, Digitalis, Pharmacology, Ouabain, Structure-Activity Relationship, Materials Chemistry, medicine, Animals, Amino Acid Sequence, Enzyme Inhibitors, Physical and Theoretical Chemistry, Binding site, Na+/K+-ATPase, Spectroscopy, Binding Sites, Sheep, biology, Chemistry, Digitalis purpurea, Digitalis Glycosides, biology.organism_classification, Computer Graphics and Computer-Aided Design, biology.protein, Sodium-Potassium-Exchanging ATPase, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae50338029a672a93bc7c83c2094ee8
https://doi.org/10.1016/j.jmgm.2005.02.001

المؤلفون: Robert Kirk DeLisle, Steven L. Dixon

المصدر: Journal of Chemical Information and Computer Sciences. 44:862-870

مصطلحات موضوعية: Computer science, business.industry, Decision tree learning, Decision Trees, Decision tree, Recursive partitioning, General Chemistry, Machine learning, computer.software_genre, Biological Evolution, Computer Science Applications, Aerobic biodegradability, Computational Theory and Mathematics, Cheminformatics, Artificial intelligence, Data mining, business, computer, Classifier (UML), Evolutionary programming, Information Systems, Interpretability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ad29226236f7d2a16fcf971b438c45
https://doi.org/10.1021/ci034188s

المؤلفون: Fraser W. Gaspar, Rachel Ostroff, Anders Grubb, Veronica Lindström, Laila Bruun, Anders Christensson, Jessica A. Ash, Robert Kirk DeLisle, Steve A. Williams

المصدر: PROTEOMICS - Clinical Applications. 12:1700067

مصطلحات موضوعية: Male, Proteomics, Oncology, medicine.medical_specialty, Clinical Biochemistry, 030232 urology & nephrology, Renal function, Context (language use), 030204 cardiovascular system & hematology, urologic and male genital diseases, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, Aged, Sex Characteristics, biology, business.industry, Beta-2 microglobulin, Blood Proteins, Middle Aged, medicine.disease, female genital diseases and pregnancy complications, Cystatin C, Proteome, biology.protein, Biomarker (medicine), Female, business, Glomerular Filtration Rate, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22efc98c910547ef4820b36837ed1d60
https://doi.org/10.1002/prca.201700067

المؤلفون: Anders Mälarstig, Robert Kirk DeLisle, Sophie Weiss, Stephen Williams, Craig L. Hyde, Rachel Ostroff

المصدر: Journal of the American College of Cardiology. 69:152

مصطلحات موضوعية: Toxicology, chemistry.chemical_compound, chemistry, Plasma samples, business.industry, Torcetrapib, Pharmacologic effects, Medicine, Early detection, Pharmacology, Cardiology and Cardiovascular Medicine, business, Proteomics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::510deda97a2fec0e0ff94a3beb0d4b5a
https://doi.org/10.1016/s0735-1097(17)33541-6