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المؤلفون: Matthias Ernst, Robert J.J. O'Donoghue, Fiona J. Pixley, Tracy L. Putoczki, Clifford A. Lowell, Megan O'Brien, Lachlan Whitehead, Michael W. Murrey, Louis Boon, David Baloyan, Ashwini L. Chand, Moritz F. Eissmann, Amy R. Dwyer, Ashleigh R. Poh
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المؤلفون: Matthias Ernst, Robert J.J. O'Donoghue, Fiona J. Pixley, Tracy L. Putoczki, Clifford A. Lowell, Megan O'Brien, Lachlan Whitehead, Michael W. Murrey, Louis Boon, David Baloyan, Ashwini L. Chand, Moritz F. Eissmann, Amy R. Dwyer, Ashleigh R. Poh
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المؤلفون: Matthias Ernst, Robert J.J. O'Donoghue, Fiona J. Pixley, Tracy L. Putoczki, Clifford A. Lowell, Megan O'Brien, Lachlan Whitehead, Michael W. Murrey, Louis Boon, David Baloyan, Ashwini L. Chand, Moritz F. Eissmann, Amy R. Dwyer, Ashleigh R. Poh
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المؤلفون: Matthias Ernst, Robert J.J. O'Donoghue, Fiona J. Pixley, Tracy L. Putoczki, Clifford A. Lowell, Megan O'Brien, Lachlan Whitehead, Michael W. Murrey, Louis Boon, David Baloyan, Ashwini L. Chand, Moritz F. Eissmann, Amy R. Dwyer, Ashleigh R. Poh
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المؤلفون: Matthias Ernst, Robert J.J. O'Donoghue, Fiona J. Pixley, Tracy L. Putoczki, Clifford A. Lowell, Megan O'Brien, Lachlan Whitehead, Michael W. Murrey, Louis Boon, David Baloyan, Ashwini L. Chand, Moritz F. Eissmann, Amy R. Dwyer, Ashleigh R. Poh
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المؤلفون: Matthias Ernst, Robert J.J. O'Donoghue, Fiona J. Pixley, Tracy L. Putoczki, Clifford A. Lowell, Megan O'Brien, Lachlan Whitehead, Michael W. Murrey, Louis Boon, David Baloyan, Ashwini L. Chand, Moritz F. Eissmann, Amy R. Dwyer, Ashleigh R. Poh
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المؤلفون: Megan O'Brien, Fiona J. Pixley, David Baloyan, Matthias Ernst, Robert J.J. O'Donoghue, Ashleigh R Poh, Tracy L Putoczki, Moritz F. Eissmann, Ashwini L. Chand, Louis Boon, Amy R. Dwyer, Clifford A. Lowell, Lachlan Whitehead, Michael W Murrey
المصدر: Cancer immunology research, vol 8, iss 4
Cancer Immunol Resمصطلحات موضوعية: Male, STAT3 Transcription Factor, 0301 basic medicine, Cancer Research, Oncology and Carcinogenesis, Immunology, Macrophage polarization, Mice, Transgenic, medicine.disease_cause, Article, Transgenic, Mice, 03 medical and health sciences, chemistry.chemical_compound, Rare Diseases, 0302 clinical medicine, Stomach Neoplasms, Genetics, medicine, Animals, Humans, Pyrroles, Phosphorylation, STAT3, Transcription factor, Cancer, biology, Kinase, Cell growth, Tyrosine phosphorylation, Pharmacology and Pharmaceutical Sciences, Macrophage Activation, Survival Rate, Pyrimidines, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Proto-Oncogene Proteins c-hck, biology.protein, Cancer research, Female, Carcinogenesis, Proto-oncogene tyrosine-protein kinase Src
وصف الملف: application/pdf
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المصدر: Journal of Gastroenterology and Hepatology
مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, medicine.medical_specialty, mouse model, Mice, Inbred Strains, Mice, Transgenic, Disease, Drug resistance, Review Article, Bioinformatics, Asymptomatic, Gastroenterology, Helicobacter Infections, 03 medical and health sciences, Stomach Neoplasms, Internal medicine, Gastrins, medicine, diffuse gastric cancer, Animals, Molecular Targeted Therapy, intestinal‐type gastric cancer, Uncategorized, Hepatology, biology, Helicobacter pylori, business.industry, Cancer, Methylnitrosourea, medicine.disease, biology.organism_classification, 3. Good health, Disease Models, Animal, 030104 developmental biology, Genetically Engineered Mouse, Helicobacter felis, medicine.symptom, business
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المؤلفون: Robert J.J. O'Donoghue, Gary P. Anderson, Caitlin O'Brien, Giuseppe D. Ciccotosto, Delaney Haugan, Mun Joo Chuei, Thomas Jaquin, Ellie H-J Cho, Goran Martic, Vanessa Welk, Andrew G. Jarnicki, Gabrielle Matschiner, Kathryn Stok
المصدر: Mechanisms of lung injury and repair.
مصطلحات موضوعية: CTGF, business.industry, Lung fibrosis, Cancer research, Medicine, Autotaxin, business, Lung function
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المؤلفون: Andrew G. Jarnicki, Caitlin O'Brien, Eva-Maria Hansbauer, Gabriele Matschiner, Gary P. Anderson, Stefan Kling, Robert J.J. O'Donoghue, Giuseppe D. Ciccotosto, Thomas Jaquin, Gabriela Segal, Mun-Joo Chuei, Ellie Cho, Shane Olwill
المصدر: Airway cell biology and immunopathology.
مصطلحات موضوعية: Biodistribution, business.industry, Imaging technology, Medicine, business, Biomedical engineering
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المؤلفون: Laura J. Jenkins, Jonathan Cebon, Nikita S. Steinohrt, Ashleigh R Poh, David S. Williams, Erinna F. Lee, W. Douglas Fairlie, Trishe Leong, Robert J.J. O'Donoghue, Tiffany J Harris, Bibhusal Thapa, Surein Arulananda, John M. Mariadason, Megan O'Brien, Marzena Walkiewicz, Xia Li, Marco Evangelista, Thomas John
المصدر: Cell Death Discovery
Cell Death Discovery, Vol 7, Iss 1, Pp 1-1 (2021)مصطلحات موضوعية: Cancer Research, biology, QH573-671, Pleural mesothelioma, business.industry, Immunology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Correction, Bcl-xL, Cell Biology, Cellular and Molecular Neuroscience, Text mining, Cancer research, biology.protein, Medicine, business, Cytology, RC254-282
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المؤلفون: Trishe Leong, Tiffany J Harris, John M. Mariadason, Robert J.J. O'Donoghue, W.D. Fairlie, Laura J. Jenkins, Jonathan Cebon, Bibhusal Thapa, Nikita S. Steinohrt, Thomas John, Marzena Walkiewicz, Megan O'Brien, Surein Arulananda, Ashleigh R Poh, David S. Williams, Erinna F. Lee, Xia Li, Marco Evangelista
المصدر: Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-11 (2020)مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_treatment, Immunology, Bcl-xL, Apoptosis, lcsh:RC254-282, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, Targeted therapies, In vivo, medicine, lcsh:QH573-671, Cisplatin, Chemotherapy, biology, Venetoclax, business.industry, lcsh:Cytology, Cancer, Cell Biology, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, 030104 developmental biology, Pemetrexed, Cell killing, chemistry, 030220 oncology & carcinogenesis, Cancer research, biology.protein, business, medicine.drug
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المؤلفون: Margaret L. Hibbs, Michael Buchert, Matthias Ernst, Frederick Masson, Alex Boussioutas, Nima Etemadi, Moritz F. Eissmann, Jamina Brunnberg, Ashleigh R Poh, Toby J. Phesse, Robert J.J. O'Donoghue, Evelyn Tsantikos, Stefan Thiem, Andrew G. Jarnicki, Nicholas D. Huntington, Christine D. Dijkstra, Michele A. Grimbaldeston
المساهمون: Cancer and Inflammation Laboratory [Heidelberg, VIC, Australia] (School of Cancer Medicine), Olivia Newton-John Cancer Research Institute [Heidelberg, VIC, Australia]-La Trobe University [Melbourne], Department of Immunology and Pathology [Melbourne, VIC, Australia], Monash University [Melbourne], Molecular Immunology Division melbourne [Melbourne, VIC, Australia], The Walter and Eliza Hall Institute of Medical Research (WEHI), Department of Medical Biology [Melbourne, VIC, Australia], University of Melbourne, Department of Medicine [Melbourne, VIC, Australia], Centre for Cancer Biology [Adelaide, SA, Australia], University of South Australia [Adelaide]-SA Pathology [Adelaide, SA, Australia], This work was supported through the Victorian State Government Operational Infrastructure Support, the Nation Health and Medical Research Council (NHMRC) of Australia grants 1092788, 1067244, 1069024 and Cancer Council Victoria’s Grant-in-Aid 1160708. M.E. is a NHMRC Principal Research Fellow and also received funding from Ludwig Cancer Research., Eissmann, Moritz F, Dijkstra, Christine, Jarnicki, Andrew, Phesse, Toby, Brunnberg, Jamina, Poh, Ashleigh R, Etemadi, Nima, Tsantikos, Evelyn, Thiem, Stefan, Huntington, Nicholas D, Hibbs, Margaret L, Boussioutas, Alex, Grimbaldeston, Michele A, Buchert, Michael, O'Donoghue, Robert JJ, Masson, Frederick, Ernst, Matthias
المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.2735. ⟨10.1038/s41467-019-10676-1⟩
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, Angiogenesis, medicine.medical_treatment, [SDV]Life Sciences [q-bio], General Physics and Astronomy, Aminopyridines, 02 engineering and technology, medicine.disease_cause, Cell Degranulation, Epithelium, Mice, Tumor Microenvironment, Mast Cells, lcsh:Science, Multidisciplinary, Chemistry, Cromolyn Sodium, 021001 nanoscience & nanotechnology, Mast cell, 3. Good health, medicine.anatomical_structure, Cytokine, Tumour immunology, Female, medicine.symptom, 0210 nano-technology, Signal Transduction, Cancer microenvironment, Science, Inflammation, Mice, Transgenic, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Stomach Neoplasms, medicine, Animals, Humans, Pyrroles, Cancer models, Tumor microenvironment, gastric cancer, Interleukins, Macrophages, General Chemistry, Interleukin-33, Interleukin-1 Receptor-Like 1 Protein, Interleukin 33, Disease Models, Animal, 030104 developmental biology, Gastric Mucosa, Tissue Array Analysis, Cancer research, lcsh:Q, interleukin (IL)-33, Carcinogenesis, mast cell, Gastric cancer
وصف الملف: application/pdf
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المؤلفون: Jenny P.-Y. Ting, Dale J. Calleja, Phil Hansbro, Katja Hrovat-Schaale, Cassandra R. Harapas, Matthias Geyer, Scott Huntsman, Esteban G. Burchard, Donglei Hu, Chien-Hsiung Yu, Seth L. Masters, Jay C. Horvat, Sophia Davidson, Marquitta J. White, Katelyn Chalker, Pawat Laohamonthonkul, Robert J.J. O'Donoghue, Motti Gerlic, Jonas Moecking, Celeste Eng
المصدر: The Journal of Allergy and Clinical Immunology
مصطلحات موضوعية: 0301 basic medicine, Allergy, Inflammasomes, ASC, Apoptosis-associated speck-like protein containing a CARD, Pathogenesis, Mice, 0302 clinical medicine, Dipeptidyl Peptidase 9, Immunology and Allergy, NLRP, Nucleotide-binding oligomerization domain-like receptor containing a pyrin domain, Mice, Knockout, SNP, Single nucleotide polymorphism, Trauma Severity Indices, OVA, Ovalbumin, NLRP1, GALA II, Genes-Environment & Admixture in Latino Americans II, Inflammasome, DPP9, Dipeptidyl peptidase 9, SAGE II, Study of African Americans, Asthma, Genes, and Environments II, Disease Susceptibility, medicine.drug, BAL, Bronchoalveolar lavage, WT, Wild-type, Immunology, SNP, NLR Proteins, Context (language use), BMI, Body mass index, Asthma and Lower Airway Disease, DPP9, Polymorphism, Single Nucleotide, Cell Line, Structure-Activity Relationship, 03 medical and health sciences, inflammasome, medicine, Animals, Humans, Genetic Predisposition to Disease, Amino Acid Sequence, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Alleles, Asthma, Innate immune system, business.industry, asthma, medicine.disease, Eosinophils, Disease Models, Animal, 030104 developmental biology, Amino Acid Substitution, Mutation, business, 030215 immunology
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المؤلفون: Matthias Ernst, Ashleigh R Poh, Robert J.J. O'Donoghue
المصدر: Oncotarget
مصطلحات موضوعية: Proto-Oncogene Proteins c-hck, SRC family kinases, Review, Receptor tyrosine kinase, Neoplasms, Animals, Humans, cancer, Medicine, Cell Proliferation, Tumor microenvironment, SFK inhibitors, Tyrosine-protein kinase CSK, biology, business.industry, Cell growth, Kinase, leukemia, 3. Good health, Cell biology, hematopoietic cell kinase, Oncology, Cancer cell, biology.protein, business, Tyrosine kinase, Signal Transduction
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16CD52 inhibits Toll-like receptor activation of NF-κB and triggers apoptosis to suppress inflammation
المؤلفون: Esther Bandala-Sanchez, John M. Wentworth, Yuxia Zhang, Leonard C. Harrison, Timothy E. Adams, James E Vince, Swarna L Vijayaraj, Alana M. Neale, Robert J.J. O'Donoghue, Kate E. Lawlor, Maryam Rashidi
مصطلحات موضوعية: 0301 basic medicine, THP-1 Cells, medicine.medical_treatment, Apoptosis, Receptors, Tumor Necrosis Factor, Proinflammatory cytokine, 03 medical and health sciences, chemistry.chemical_compound, Mice, medicine, Animals, Humans, Molecular Biology, Inflammation, Mice, Knockout, Toll-like receptor, Original Paper, Innate immune system, Chemistry, Macrophages, Toll-Like Receptors, NF-kappa B, NF-κB, Cell Biology, Healthy Volunteers, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, Cytokine, CD52 Antigen, Cytokines, Cytokine secretion, Tumor necrosis factor alpha, Immunotherapy, Signal transduction, Signal Transduction
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المؤلفون: Frederick Masson, Tracy L Putoczki, Oliver M. Sieber, Yelena Khakham, Cary Tsui, Lotta Burstroem, Ashleigh R Poh, Matthias Ernst, Clifford A. Lowell, Robert J.J. O'Donoghue, Adele Preaudet, Lachlan Whitehead, Guillaume Lessene, Simon Monard, Christopher G. Love
المساهمون: Olivia Newton-John Cancer Research Institute, La Trobe University School of Cancer Medicine, Heidelberg, VIC 3084, Australia, The Walter and Eliza Hall Institute of Medical Research, Department of Medical Biology, University of Melbourne, Melbourne, VIC 3052, Australia.
المصدر: Cancer Cell
Cancer Cell, Elsevier, 2017, 31 (4), pp.563-575.e5. ⟨10.1016/j.ccell.2017.03.006⟩
Cancer cell, vol 31, iss 4مصطلحات موضوعية: 0301 basic medicine, MESH: Signal Transduction, Cancer Research, Colorectal cancer, [SDV]Life Sciences [q-bio], Cell, Inbred C57BL, medicine.disease_cause, MESH: Mice, Knockout, Mice, 0302 clinical medicine, tyrosine kinase inhibitor, 2.1 Biological and endogenous factors, MESH: Animals, Src family kinase, Aetiology, Cancer, Mice, Knockout, MESH: STAT3 Transcription Factor, MESH: Macrophage Activation, Hematology, MESH: Gene Expression Regulation, Neoplastic, Colo-Rectal Cancer, 3. Good health, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, colitis-associated colon cancer, hematopoietic cell kinase, Oncology, 030220 oncology & carcinogenesis, Colonic Neoplasms, MESH: Pyrroles, Proto-Oncogene Proteins c-hck, Female, Signal transduction, Colorectal Neoplasms, MESH: Proto-Oncogene Proteins c-hck, alternative macrophage polarization, Signal Transduction, STAT3 Transcription Factor, MESH: Xenograft Model Antitumor Assays, Knockout, SRC family kinases, mouse model, Oncology and Carcinogenesis, colorectal cancer, Biology, stat3, Article, 03 medical and health sciences, Rare Diseases, MESH: Mice, Inbred C57BL, medicine, tumor microenvironment, Animals, Humans, Pyrroles, Oncology & Carcinogenesis, xenograft, MESH: Colonic Neoplasms, Neoplastic, Tumor microenvironment, MESH: Humans, Oncogene, Neurosciences, Cell Biology, Macrophage Activation, medicine.disease, Xenograft Model Antitumor Assays, Mice, Inbred C57BL, 030104 developmental biology, Pyrimidines, Gene Expression Regulation, MESH: Pyrimidines, Cancer research, MESH: Stromal Cells, Stromal Cells, Digestive Diseases, Carcinogenesis, MESH: Female, MESH: Colorectal Neoplasms
وصف الملف: application/pdf
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المؤلفون: Ivan Bertoncello, Marie Liesse Asselin-Labat, Joanne Van der Velden, Robert J.J. O'Donoghue, Rosa C. McCarty, Jonathan L. McQualter, Steven Bozinovski
المصدر: Stem Cell Research. 11(3):1222-1233
مصطلحات موضوعية: Stromal cell, Cellular differentiation, Dioxoles, Mice, 03 medical and health sciences, 0302 clinical medicine, Transforming Growth Factor beta, Activated-Leukocyte Cell Adhesion Molecule, Lymph node stromal cell, Animals, Cell Lineage, Progenitor cell, Myofibroblasts, Lung, Cells, Cultured, Cell Proliferation, 030304 developmental biology, Medicine(all), 0303 health sciences, biology, Stem Cells, Mesenchymal stem cell, Cell Differentiation, Epithelial Cells, General Medicine, Transforming growth factor beta, Cell Biology, Up-Regulation, Cell biology, Mice, Inbred C57BL, 030220 oncology & carcinogenesis, Benzamides, Immunology, biology.protein, Female, Stromal Cells, Stem cell, Fibroblast Growth Factor 10, Signal Transduction, Adult stem cell, Developmental Biology
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المؤلفون: Brent S. McKenzie, Bo Wang, Carl D. Richards, Philip A. Stumbles, Steven E. Mutsaers, Geoffrey J. Laurent, Gary P. Anderson, Darryl A. Knight, Ross Vlahos, Jessica E Jones, Hong-Jian Zhu, Hui Ling Lau, Matthias Ernst, Steven Bozinovski, Robin J. McAnulty, Robert J.J. O'Donoghue, Cecilia M. Prêle, Stefan Thiem, Stefan Rose-John, Andrew G. Jarnicki
المصدر: EMBO Molecular Medicine
مصطلحات موضوعية: Male, STAT3 Transcription Factor, medicine.medical_treatment, interleukin 6, Proinflammatory cytokine, 03 medical and health sciences, Idiopathic pulmonary fibrosis, Bleomycin, Mice, 0302 clinical medicine, Fibrosis, Pulmonary fibrosis, medicine, Cytokine Receptor gp130, Animals, Smad3 Protein, Interleukin 6, STAT3, Research Articles, 030304 developmental biology, transforming growth factor beta, Mice, Knockout, 0303 health sciences, biology, pulmonary fibrosis, Stat3, Interleukin-6, Genetic Complementation Test, Interleukin, respiratory system, medicine.disease, 3. Good health, respiratory tract diseases, Mice, Inbred C57BL, Cytokine, 030220 oncology & carcinogenesis, Immunology, Cancer research, biology.protein, Molecular Medicine, Smad3
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المؤلفون: Ashleigh R Poh, Robert J.J. O'Donoghue, Matthias Ernst
المصدر: Oncoscience
مصطلحات موضوعية: Cancer Research, polarization, Hck, business.industry, Cancer therapy, Cancer, medicine.disease, macrophages, Text mining, Editorial, Oncology, myeloid cells, Myeloid cells, Cancer research, medicine, cancer, business