المؤلفون: Lindsay E. Clegg, Lulu Chu, Mats Nagard, David W. Boulton, Robert C. Penland

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 2, Pp 296-307 (2024)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2163-8306

URL الوصول: https://doaj.org/article/13e156a6bf924f898f09a9f1f969e99c

المؤلفون: Victor Sokolov, Tatiana Yakovleva, Leonid Stolbov, Robert C. Penland, David Boulton, Joanna Parkinson, Weifeng Tang

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 6, Pp 831-841 (2023)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2163-8306

URL الوصول: https://doaj.org/article/08d955a3d7174494a0f64eaccfc0dd49

المؤلفون: Victor Sokolov, Tatiana Yakovleva, Robert C. Penland, David W. Boulton, Weifeng Tang

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: continuous glucose monitoring, dapagliflozin, insulin, exposure-response model, SGLT-2 inhibitor, HbA1c, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1229255/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/b7bcb824b744490195e37975eee3fdf2

المؤلفون: Victor Sokolov, Tatiana Yakovleva, Lulu Chu, Weifeng Tang, Peter J. Greasley, Susanne Johansson, Kirill Peskov, Gabriel Helmlinger, David W. Boulton, Robert C. Penland

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 4, Pp 222-229 (2020)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2163-8306

URL الوصول: https://doaj.org/article/4f5804238a5a4ff3b4cb5e7de0343122

المؤلفون: Lindsay E. Clegg, Robert C. Penland, Srinivas Bachina, David W. Boulton, Marcus Thuresson, Hiddo J. L. Heerspink, Stephanie Gustavson, C. David Sjöström, James A. Ruggles, Adrian F. Hernandez, John B. Buse, Robert J. Mentz, Rury R. Holman

المصدر: Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-12 (2019)

مصطلحات موضوعية: SGLT2 inhibitor, GLP-1 receptor agonist, Exenatide, Cardiovascular outcomes, eGFR slope, Type 2 diabetes mellitus, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12933-019-0942-x; https://doaj.org/toc/1475-2840

URL الوصول: https://doaj.org/article/3fa36748485b487cb3cfa5fcb2b66bfd

المؤلفون: Gabriel Helmlinger, Victor Sokolov, Kirill Peskov, Karen M. Hallow, Yuri Kosinsky, Veronika Voronova, Lulu Chu, Tatiana Yakovleva, Ivan Azarov, Daniel Kaschek, Artem Dolgun, Henning Schmidt, David W. Boulton, Robert C. Penland

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 6, Pp 380-395 (2019)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2163-8306

URL الوصول: https://doaj.org/article/0bc86cacff10421bbe8ac64b3a5e719b

المؤلفون: Joanna Parkinson, David W. Boulton, Weifeng Tang, Robert C. Penland, Bengt Hamrén, Melin J, Dinko Rekić

المصدر: The Journal of Clinical Pharmacology. 62:1227-1235

مصطلحات موضوعية: Adult, Blood Glucose, Male, endocrine system diseases, Pharmacology, chemistry.chemical_compound, Clinical Trials, Phase II as Topic, Glucosides, Pharmacokinetics, Humans, Hypoglycemic Agents, Medicine, Pharmacology (medical), Benzhydryl Compounds, Dapagliflozin, Dose-Response Relationship, Drug, business.industry, nutritional and metabolic diseases, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 1, Clinical Trials, Phase III as Topic, Diabetes Mellitus, Type 2, chemistry, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b579476a26ab5879587b6096ae6b72
https://doi.org/10.1002/jcph.2062

المؤلفون: Victor Sokolov, Tatiana Yakovleva, Robert C. Penland, David W. Boulton, Weifeng Tang

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, continuous glucose monitoring, dapagliflozin, insulin, exposure-response model, SGLT-2 inhibitor, HbA1c, type 1 diabetes

Relation: https://figshare.com/articles/dataset/Table1_Effectiveness_of_dapagliflozin_as_an_insulin_adjunct_in_type_1_diabetes_a_semi-mechanistic_exposure-response_model_DOC/24432586

الاتاحة: https://doi.org/10.3389/fphar.2023.1229255.s001
https://figshare.com/articles/dataset/Table1_Effectiveness_of_dapagliflozin_as_an_insulin_adjunct_in_type_1_diabetes_a_semi-mechanistic_exposure-response_model_DOC/24432586

المؤلفون: Robert C. Penland, Johanna Melin, David W. Boulton, Weifeng Tang

المصدر: Journal of clinical pharmacology.

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6e711116ce91f487babc0bfc7ae16f9
https://pubmed.ncbi.nlm.nih.gov/36543754

المؤلفون: Adrian F. Hernandez, Yankang Jing, Lindsay E. Clegg, David W. Boulton, Robert C. Penland, Rury R. Holman, Jiten Vora

المصدر: Diabetes, Obesity and Metabolism. 23:1101-1110

مصطلحات موضوعية: medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Population, 030209 endocrinology & metabolism, 030204 cardiovascular system & hematology, Saxagliptin, Kidney, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Humans, Renal Insufficiency, Chronic, education, education.field_of_study, business.industry, Hazard ratio, medicine.disease, Metformin, Diabetes Mellitus, Type 2, chemistry, Cardiovascular Diseases, business, Exenatide, Mace, Glomerular Filtration Rate, medicine.drug, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07783e36457121ec71912c33b78c1efa
https://doi.org/10.1111/dom.14313

المؤلفون: Millie Shah, Robert C. Penland, Leonid Stolbov, Tatiana Yakovleva, Victor Sokolov, David W. Boulton, Weifeng Tang, Joanna Parkinson

المصدر: Diabetes, Obesity and Metabolism. 23:991-1000

مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, 030209 endocrinology & metabolism, Type 2 diabetes, 030204 cardiovascular system & hematology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Glucosides, Internal medicine, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Insulin, Benzhydryl Compounds, Dapagliflozin, Glycemic, business.industry, Type 2 Diabetes Mellitus, medicine.disease, Renal glucose reabsorption, Glucose, Treatment Outcome, Diabetes Mellitus, Type 2, chemistry, Glycated hemoglobin, SGLT2 Inhibitor, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76563be4be1eea60c59a4d2a5f58b0f9
https://doi.org/10.1111/dom.14305

المؤلفون: Robert C. Penland, Annemarie B van der Aart-van der Beek, Rury R. Holman, David W. Boulton, Hiddo J.L. Heerspink, Lindsay E. Clegg, Robert J. Mentz, C. David Sjöström

المساهمون: Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Groningen Kidney Center (GKC)

المصدر: Diabetes, Obesity & Metabolism
Diabetes, Obesity and Metabolism, 22(12), 2493-2498. Wiley

مصطلحات موضوعية: medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, exenatide, Urology, Renal function, 030209 endocrinology & metabolism, Type 2 diabetes, 030204 cardiovascular system & hematology, Kidney, Kidney Function Tests, Placebo, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Post-hoc analysis, Internal Medicine, medicine, Humans, glucagon‐like peptide‐1 receptor agonists, glucagon-like peptide-1 receptor agonists, Creatinine, business.industry, Brief Report, Repeated measures design, GLP‐1RA, medicine.disease, GLP-1RA, Confidence interval, diabetic kidney disease, Diabetes Mellitus, Type 2, chemistry, Brief Reports, pooled analysis, business, Exenatide, Glomerular Filtration Rate, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270e1130a3a50044844c14f3dc0e921b
https://doi.org/10.1111/dom.14175

المؤلفون: Robert C. Penland, Emily Nieves, Daniël H. van Raalte, Peter J. Greasley, David W. Boulton, Hiddo J.L. Heerspink, K. Melissa Hallow, Gabriel Helmlinger

المساهمون: Internal medicine, ACS - Diabetes & metabolism, Amsterdam Gastroenterology Endocrinology Metabolism, Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Groningen Kidney Center (GKC)

المصدر: Hallow, K M, Boulton, D W, Penland, R C, Helmlinger, G, Nieves, E H, van Raalte, D H, Heerspink, H L & Greasley, P J 2020, ' Renal effects of dapagliflozin in people with and without diabetes with moderate or severe renal dysfunction: Prospective modeling of an ongoing clinical trial ', Journal of Pharmacology and Experimental Therapeutics, vol. 375, no. 1, pp. 76-91 . https://doi.org/10.1124/JPET.120.000040
Journal of Pharmacology and Experimental Therapeutics, 375(1), 76-91. American Society for Pharmacology and Experimental Therapeutics
Journal of Pharmacology and Experimental Therapeutics, 375(1), 76-91. WILLIAMS & WILKINS

مصطلحات موضوعية: 0301 basic medicine, Glycosuria, medicine.medical_specialty, Hydrostatic pressure, Renal function, Type 2 diabetes, Clinical Trials, Phase IV as Topic, Kidney, urologic and male genital diseases, Models, Biological, Severity of Illness Index, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Glucosides, Sodium-Glucose Transporter 2, Diabetes mellitus, Internal medicine, medicine, Humans, Diabetic Nephropathies, Renal Insufficiency, Dapagliflozin, Benzhydryl Compounds, Sodium-Glucose Transporter 2 Inhibitors, Randomized Controlled Trials as Topic, Pharmacology, business.industry, medicine.disease, 030104 developmental biology, chemistry, Diabetes Mellitus, Type 2, Renal physiology, Albuminuria, Cardiology, Molecular Medicine, medicine.symptom, business, 030217 neurology & neurosurgery, Glomerular Filtration Rate

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf6fc056774d9bdd8b4f44af8f86b55
https://hdl.handle.net/11370/423755ff-71e3-4395-95f5-b5c327be53f0

المؤلفون: Artem Dolgun, Robert C. Penland, Daniel Kaschek, Karen M. Hallow, David W. Boulton, Tatiana Yakovleva, Veronika Voronova, Gabriel Helmlinger, Lulu Chu, Henning Schmidt, Yuri Kosinsky, Ivan Azarov, Kirill Peskov, Victor Sokolov

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 8, Iss 6, Pp 380-395 (2019)
CPT: Pharmacometrics & Systems Pharmacology

مصطلحات موضوعية: Computer science, Systems Biology, lcsh:RM1-950, Reviews, Review, Asset (computer security), Exemplar theory, Workflow, Drug class, lcsh:Therapeutics. Pharmacology, Drug development, Risk analysis (engineering), Drug Development, Modeling and Simulation, Pharmacology, Clinical, Oncology drug, Humans, Hypoglycemic Agents, Pharmacology (medical), Sodium-Glucose Transporter 2 Inhibitors, Software, Systems pharmacology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8393857a7582c34d0ccc4c17a8669a0
https://doaj.org/article/0bc86cacff10421bbe8ac64b3a5e719b

المؤلفون: Peter J. Greasley, Jan Oscarsson, Hongtao Yu, David W. Boulton, Weifeng Tang, Sanchita Basu, Robert C. Penland, K. Melissa Hallow

المصدر: Journal of clinical pharmacologyReferences. 62(4)

مصطلحات موضوعية: Cardiac function curve, medicine.medical_specialty, Population, Hemodynamics, Placebo, chemistry.chemical_compound, Internal medicine, medicine, Humans, Pharmacology (medical), Dapagliflozin, education, Sodium-Glucose Transporter 2 Inhibitors, Pharmacology, Heart Failure, education.field_of_study, Ejection fraction, business.industry, Stroke Volume, Models, Theoretical, medicine.disease, Clinical trial, chemistry, Diabetes Mellitus, Type 2, Heart failure, Cardiology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8e29e7da2243802e2a9541b9826752
https://pubmed.ncbi.nlm.nih.gov/34657303

المؤلفون: Robert C. Penland, David W. Boulton, Weifeng Tang, Hongtao Yu, K. Melissa Hallow, Peter J. Greasley

المصدر: Journal of clinical pharmacologyReferences. 61(5)

مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, Population, Hemodynamics, Natriuresis, Blood volume, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Glucosides, Glomerular Filtration Barrier, Internal medicine, medicine, Humans, Pharmacology (medical), Computer Simulation, Benzhydryl Compounds, education, Sodium-Glucose Transporter 2 Inhibitors, Pharmacology, Heart Failure, education.field_of_study, Ejection fraction, Blood Volume, business.industry, Models, Theoretical, medicine.disease, Diuresis, Preload, medicine.anatomical_structure, Diabetes Mellitus, Type 2, Hematocrit, Ventricle, 030220 oncology & carcinogenesis, Heart failure, Cardiology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a05cefb6a4b2392bf38446e926aa36d
https://pubmed.ncbi.nlm.nih.gov/33091173

المؤلفون: null Annemarie B van der Aart‐van der Beek, null Lindsay E. Clegg, null Robert C. Penland, null David W. Boulton, null C. David Sjöström, null Robert J. Mentz, null Rury R. Holman, null Hiddo J. L. Heerspink

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ea9f6f19439f61305d102a78dc986e36
https://doi.org/10.1111/dom.14175/v3/response1

المؤلفون: David W. Boulton, Hiddo J.L. Heerspink, Rury R. Holman, Lindsay E. Clegg, Robert C. Penland, Robert J. Mentz, C. David Sjöström, Annemarie B. van der Aart-van der Beek

مصطلحات موضوعية: medicine.medical_specialty, business.industry, Internal medicine, Post-hoc analysis, medicine, Once weekly, business, Baseline (configuration management), Exenatide, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2f608cd8d95054236bebebef8f27d49b
https://doi.org/10.1111/dom.14175/v2/response1

المؤلفون: David W. Boulton, Robert C. Penland, Robert J. Mentz, C. David Sjöström, Hiddo L. Heerspink, Rury R. Holman, Lindsay E. Clegg, Annemarie Van Der Aart

المصدر: Diabetes. 69

مصطلحات موضوعية: education.field_of_study, medicine.medical_specialty, business.industry, Endocrinology, Diabetes and Metabolism, Population, Repeated measures design, Once weekly, Median time, Internal medicine, Post-hoc analysis, Internal Medicine, medicine, education, business, Exenatide, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::88250480e219724a9d354da5896a9cd5
https://doi.org/10.2337/db20-958-p

المؤلفون: Robert C. Penland, Robert Fox, Rury R. Holman, Adrian F. Hernandez, David W. Boulton, Weifeng Tang, Hiddo J.L. Heerspink, Robert J. Mentz, Srinivas Bachina, Lindsay E. Clegg, Marcus Thuresson, Peter Fenici

المساهمون: Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Groningen Kidney Center (GKC), Methods in Medicines evaluation & Outcomes research (M2O)

المصدر: Diabetes Care, 42(2), 318-326. AMER DIABETES ASSOC

مصطلحات موضوعية: Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Urology, 030209 endocrinology & metabolism, Placebo, Lower risk, Kidney, Placebos, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Glucosides, Risk Factors, Post-hoc analysis, Internal Medicine, Empagliflozin, Medicine, Humans, 030212 general & internal medicine, Dapagliflozin, Benzhydryl Compounds, Canagliflozin, Sodium-Glucose Transporter 2 Inhibitors, Aged, Advanced and Specialized Nursing, business.industry, Incidence, Hazard ratio, Middle Aged, Treatment Outcome, chemistry, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Female, business, Mace, Diabetic Angiopathies, medicine.drug, Glomerular Filtration Rate

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51d4b8bc7c13d13c9ed90509ac1e81e
https://research.rug.nl/en/publications/99fbfd17-b93c-4e22-9815-ca5b744405de