المؤلفون: Rob Hooft van Huijsduijnen, Timothy Wells, Marcel Tanner, Sergio Wittlin

المصدر: Malaria Journal, Vol 18, Iss 1, Pp 1-7 (2019)

مصطلحات موضوعية: Malaria, Drug discovery, Product-development-partnership, Switzerland, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-019-2728-8; https://doaj.org/toc/1475-2875

URL الوصول: https://doaj.org/article/8d40a684301d46429ffb0e40df113729

المؤلفون: Jeremy Burrows, Hannah Slater, Fiona Macintyre, Sarah Rees, Anna Thomas, Fredros Okumu, Rob Hooft van Huijsduijnen, Stephan Duparc, Timothy N. C. Wells

المصدر: Malaria Journal, Vol 17, Iss 1, Pp 1-15 (2018)

مصطلحات موضوعية: Malaria, Plasmodium, Transmission blocking, Endectocides, target candidate profile, Target product profile, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-018-2598-5; https://doaj.org/toc/1475-2875

URL الوصول: https://doaj.org/article/469e9b7621fd4e0fb191a87cd6d354f4

المؤلفون: Fiona Macintyre, Hanu Ramachandruni, Jeremy N. Burrows, René Holm, Anna Thomas, Jörg J. Möhrle, Stephan Duparc, Rob Hooft van Huijsduijnen, Brian Greenwood, Winston E. Gutteridge, Timothy N. C. Wells, Wiweka Kaszubska

المصدر: Malaria Journal, Vol 17, Iss 1, Pp 1-18 (2018)

مصطلحات موضوعية: Malaria, Plasmodium, Chemoprotection, Prophylaxis, Liver schizont, Intra-muscular, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-018-2549-1; https://doaj.org/toc/1475-2875

URL الوصول: https://doaj.org/article/dbdcceb481fa497fa620c83328de23ba

المؤلفون: Jeremy N. Burrows, Stephan Duparc, Winston E. Gutteridge, Rob Hooft van Huijsduijnen, Wiweka Kaszubska, Fiona Macintyre, Sébastien Mazzuri, Jörg J. Möhrle, Timothy N. C. Wells

المصدر: Malaria Journal, Vol 16, Iss 1, Pp 1-5 (2017)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-017-1809-9; https://doaj.org/toc/1475-2875

URL الوصول: https://doaj.org/article/0db67e0cbf7c4a8ba7a34e1ed7147e7b

المؤلفون: Rob Hooft van Huijsduijnen, Somei Kojima, Dee Carter, Hisafumi Okabe, Akihide Sato, Wataru Akahata, Timothy N C Wells, Kei Katsuno

المصدر: PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007860 (2020)

مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

URL الوصول: https://doaj.org/article/f943fdcc8ea44d97886eddaabf3dcef9

المؤلفون: Emilie Alirol, Teodora E Wi, Manju Bala, Maria Luiza Bazzo, Xiang-Sheng Chen, Carolyn Deal, Jo-Anne R Dillon, Ranmini Kularatne, Jutta Heim, Rob Hooft van Huijsduijnen, Edward W Hook, Monica M Lahra, David A Lewis, Francis Ndowa, William M Shafer, Liz Tayler, Kimberly Workowski, Magnus Unemo, Manica Balasegaram

المصدر: PLoS Medicine, Vol 14, Iss 7, p e1002366 (2017)

مصطلحات موضوعية: Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

URL الوصول: https://doaj.org/article/9bfd3337f3684f99b2c8f78cbd2a4365

المؤلفون: Wesley C Van Voorhis, John H Adams, Roberto Adelfio, Vida Ahyong, Myles H Akabas, Pietro Alano, Aintzane Alday, Yesmalie Alemán Resto, Aishah Alsibaee, Ainhoa Alzualde, Katherine T Andrews, Simon V Avery, Vicky M Avery, Lawrence Ayong, Mark Baker, Stephen Baker, Choukri Ben Mamoun, Sangeeta Bhatia, Quentin Bickle, Lotfi Bounaadja, Tana Bowling, Jürgen Bosch, Lauren E Boucher, Fabrice F Boyom, Jose Brea, Marian Brennan, Audrey Burton, Conor R Caffrey, Grazia Camarda, Manuela Carrasquilla, Dee Carter, Maria Belen Cassera, Ken Chih-Chien Cheng, Worathad Chindaudomsate, Anthony Chubb, Beatrice L Colon, Daisy D Colón-López, Yolanda Corbett, Gregory J Crowther, Noemi Cowan, Sarah D'Alessandro, Na Le Dang, Michael Delves, Joseph L DeRisi, Alan Y Du, Sandra Duffy, Shimaa Abd El-Salam El-Sayed, Michael T Ferdig, José A Fernández Robledo, David A Fidock, Isabelle Florent, Patrick V T Fokou, Ani Galstian, Francisco Javier Gamo, Suzanne Gokool, Ben Gold, Todd Golub, Gregory M Goldgof, Rajarshi Guha, W Armand Guiguemde, Nil Gural, R Kiplin Guy, Michael A E Hansen, Kirsten K Hanson, Andrew Hemphill, Rob Hooft van Huijsduijnen, Takaaki Horii, Paul Horrocks, Tyler B Hughes, Christopher Huston, Ikuo Igarashi, Katrin Ingram-Sieber, Maurice A Itoe, Ajit Jadhav, Amornrat Naranuntarat Jensen, Laran T Jensen, Rays H Y Jiang, Annette Kaiser, Jennifer Keiser, Thomas Ketas, Sebastien Kicka, Sunyoung Kim, Kiaran Kirk, Vidya P Kumar, Dennis E Kyle, Maria Jose Lafuente, Scott Landfear, Nathan Lee, Sukjun Lee, Adele M Lehane, Fengwu Li, David Little, Liqiong Liu, Manuel Llinás, Maria I Loza, Aristea Lubar, Leonardo Lucantoni, Isabelle Lucet, Louis Maes, Dalu Mancama, Nuha R Mansour, Sandra March, Sheena McGowan, Iset Medina Vera, Stephan Meister, Luke Mercer, Jordi Mestres, Alvine N Mfopa, Raj N Misra, Seunghyun Moon, John P Moore, Francielly Morais Rodrigues da Costa, Joachim Müller, Arantza Muriana, Stephen Nakazawa Hewitt, Bakela Nare, Carl Nathan, Nathalie Narraidoo, Sujeevi Nawaratna, Kayode K Ojo, Diana Ortiz, Gordana Panic, George Papadatos, Silvia Parapini, Kailash Patra, Ngoc Pham, Sarah Prats, David M Plouffe, Sally-Ann Poulsen, Anupam Pradhan, Celia Quevedo, Ronald J Quinn, Christopher A Rice, Mohamed Abdo Rizk, Andrea Ruecker, Robert St Onge, Rafaela Salgado Ferreira, Jasmeet Samra, Natalie G Robinett, Ulrich Schlecht, Marjorie Schmitt, Filipe Silva Villela, Francesco Silvestrini, Robert Sinden, Dennis A Smith, Thierry Soldati, Andreas Spitzmüller, Serge Maximilian Stamm, David J Sullivan, William Sullivan, Sundari Suresh, Brian M Suzuki, Yo Suzuki, S Joshua Swamidass, Donatella Taramelli, Lauve R Y Tchokouaha, Anjo Theron, David Thomas, Kathryn F Tonissen, Simon Townson, Abhai K Tripathi, Valentin Trofimov, Kenneth O Udenze, Imran Ullah, Cindy Vallieres, Edgar Vigil, Joseph M Vinetz, Phat Voong Vinh, Hoan Vu, Nao-Aki Watanabe, Kate Weatherby, Pamela M White, Andrew F Wilks, Elizabeth A Winzeler, Edward Wojcik, Melanie Wree, Wesley Wu, Naoaki Yokoyama, Paul H A Zollo, Nada Abla, Benjamin Blasco, Jeremy Burrows, Benoît Laleu, Didier Leroy, Thomas Spangenberg, Timothy Wells, Paul A Willis

المصدر: PLoS Pathogens, Vol 12, Iss 7, p e1005763 (2016)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/18b88a00726d44659ebd19c6f7c84d1b

المؤلفون: Rob Hooft van Huijsduijnen, R Kiplin Guy, Kelly Chibale, Richard K Haynes, Ingmar Peitz, Gerhard Kelter, Margaret A Phillips, Jonathan L Vennerstrom, Yongyuth Yuthavong, Timothy N C Wells

المصدر: PLoS ONE, Vol 8, Iss 12, p e82962 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3877007?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/3601c2ce5a7440359cead33171a26b33

المؤلفون: Fanny Schmidt, Monique van den Eijnden, Rosanna Pescini Gobert, Gabriela P Saborio, Susanna Carboni, Chantal Alliod, Sandrine Pouly, Susan M Staugaitis, Ranjan Dutta, Bruce Trapp, Rob Hooft van Huijsduijnen

المصدر: PLoS ONE, Vol 7, Iss 7, p e40457 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3394735?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/8575d61af49245e7b5900332fdbc6c00

المؤلفون: Rob Hooft van Huijsduijnen

المصدر: BioTechniques, Vol 24, Iss 3, Pp 390-392 (1998)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

URL الوصول: https://doaj.org/article/f77c04554a3441dda5f69e035f4dfaae

المؤلفون: Kirandeep Samby, Dominique Besson, Anirban Dutta, Buddhadev Patra, Angelique Doy, Paul Glossop, James Mills, Gavin Whitlock, Rob Hooft van Huijsduijnen, Alessandra Monaco, Graeme Bilbe, Charles Mowbray, Benjamin Perry, Anna Adam, Timothy N. C. Wells, Paul A. Willis

المصدر: ACS Infectious Diseases. 8:713-720

مصطلحات موضوعية: Infectious Diseases, Drug Discovery, Humans, Pandemics, Disease Outbreaks, COVID-19 Drug Treatment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e787f081547a1c3c5595fdfad5b8691
https://doi.org/10.1021/acsinfecdis.1c00527

المؤلفون: Rob Hooft van Huijsduijnen, Timothy N. C. Wells

المصدر: Current Opinion in Pharmacology. 42:1-6

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Computer science, 030231 tropical medicine, Computational biology, Drug resistance, medicine.disease, Pipeline (software), Malaria, Dynamic resistance, Antimalarials, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Drug development, Drug Discovery, medicine, Animals, Humans, Severe Malaria, Disease transmission

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac10f798a1e594ae6e3e425a52da691
https://doi.org/10.1016/j.coph.2018.05.006

المؤلفون: Christian Pasquali, Hong Ji, Christian Rommel, Corine Gillieron, Cornelia Weiss-Haljiti, Christian Chabert, Montserrat Camps, Anne J. Ridley, Emilio Hirsch, Rob Hooft van Huijsduijnen, Marie-Laure Curchod

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

Relation: url:https://www.openaccessrepository.it/communities/itmirror; https://www.openaccessrepository.it/record/95249

الاتاحة: https://www.openaccessrepository.it/record/95249
https://doi.org/10.1074/jbc.m402924200

المؤلفون: Jörg J. Möhrle, Peter O'Rourke, James S. McCarthy, Louise Marquart, Paul M. Griffin, Mark Baker, Rob Hooft van Huijsduijnen

المصدر: Journal of Antimicrobial Chemotherapy

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Microbiology (medical), Drug, Artemisinins, Adolescent, Combination therapy, media_common.quotation_subject, Plasmodium falciparum, 030106 microbiology, 030231 tropical medicine, Administration, Oral, Adamantane, Microbial Sensitivity Tests, Pharmacology, Real-Time Polymerase Chain Reaction, Parasite Load, Cohort Studies, Antimalarials, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, medicine, Humans, Potency, Pharmacology (medical), Malaria, Falciparum, Original Research, media_common, biology, business.industry, biology.organism_classification, medicine.disease, Healthy Volunteers, Peroxides, 3. Good health, Treatment Outcome, Infectious Diseases, Pharmacodynamics, Immunology, Female, business, Malaria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9159490c90929f1ad65555bdabc8f1
https://doi.org/10.1093/jac/dkw174

المؤلفون: Suzanne L. Elliott, Rebecca Rockett, Santiago Ferrer, Mark Baker, Timothy N. C. Wells, Theo P. Sloots, Louise Marquart, James S. McCarthy, Rob Hooft van Huijsduijnen, María Belén Jiménez-Díaz, Katharine R. Trenholme, Jörg J. Möhrle, Didier Leroy, María-Santos Martínez, Paul M. Griffin, Stephan Duparc, Peter O'Rourke, Silvana Sekuloski, Iñigo Angulo-Barturen

المصدر: Antimicrobial Agents and Chemotherapy

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Erythrocytes, 030106 microbiology, Plasmodium falciparum, Mice, SCID, Pharmacology, Drug Administration Schedule, Cohort Studies, 03 medical and health sciences, Antimalarials, Inhibitory Concentration 50, Mice, Pharmacokinetics, In vivo, Mice, Inbred NOD, Medicine, Animals, Humans, Pharmacology (medical), Experimental Therapeutics, Drug Dosage Calculations, Malaria, Falciparum, Mice, Knockout, biology, business.industry, Mefloquine, medicine.disease, biology.organism_classification, Healthy Volunteers, 3. Good health, Clinical trial, Disease Models, Animal, Infectious Diseases, Drug development, Immunology, Female, Onset of action, business, Malaria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0cad1871eb18397dba231a1b1068231
http://europepmc.org/articles/PMC4879391

المؤلفون: Jacqueline Chrast-balz, Rob Hooft Van Huijsduijnen

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://nar.oxfordjournals.org/content/24/15/2900.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.5749; http://nar.oxfordjournals.org/content/24/15/2900.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.5749
http://nar.oxfordjournals.org/content/24/15/2900.full.pdf

المؤلفون: Paola Ghersa, James Whelan, Yves Cambet, John F. Delamarter, Rob Hooft Van Huijsduijnen

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://nar.oxfordjournals.org/content/25/2/339.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.320.7443; http://nar.oxfordjournals.org/content/25/2/339.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.320.7443
http://nar.oxfordjournals.org/content/25/2/339.full.pdf

المؤلفون: Wesley C. Van Voorhis, Timothy N. C. Wells, Rob Hooft van Huijsduijnen

المصدر: Proceedings of the National Academy of Sciences. 112:15773-15776

مصطلحات موضوعية: medicine.medical_specialty, Ivermectin, Multidisciplinary, Physiology, business.industry, Alternative medicine, MEDLINE, Historical Article, Biography, History, 20th Century, History, 21st Century, Artemisinins, Nobel Prize, Portrait, Drug Discovery, Parasitic Diseases, Medicine, Profile, Clinical Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f25b0f0358280a466389b2cf412164c
https://doi.org/10.1073/pnas.1520952112

المؤلفون: Margaret A. Phillips, Jeremy N. Burrows, Christine Manyando, Rob Hooft van Huijsduijnen, Wesley C. Van Voorhis, Timothy N. C. Wells

المصدر: Nature reviews. Disease primers. 3

مصطلحات موضوعية: 0301 basic medicine, Male, Insecticides, Plasmodium, Mosquito Control, 030231 tropical medicine, Plasmodium falciparum, Drug Resistance, Mosquito Vectors, 03 medical and health sciences, Antimalarials, 0302 clinical medicine, Anti-Infective Agents, Anopheles, Animals, Humans, Insecticide-Treated Bednets, Infant, General Medicine, Artemisinins, Malaria, 030104 developmental biology, Child, Preschool, Africa, Female, Plasmodium vivax

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f564512d198fceb6a3f75c32107ca578
https://pubmed.ncbi.nlm.nih.gov/28770814

المؤلفون: Jaap Heringa, Elena Santonico, Michele Tinti, Mike Schutkowski, Rob Hooft van Huijsduijnen, Antonia Masch, A. Palma, Serena Paoluzi, Luisa Castagnoli, Gianni Cesareni, Bernd W. Brandt

المساهمون: Bioinformatics, AIMMS, Integrative Bioinformatics

المصدر: Journal of Biological Chemistry, 292(12), 4942-4958. American Society for Biochemistry and Molecular Biology Inc.
Palma, A, Tinti, M, Paoluzi, S, Santonico, E, Brandt, B W, Hooft Van Huijsduijnen, R, Masch, A, Heringa, J, Schutkowski, M, Castagnoli, L & Cesareni, G 2017, ' Both intrinsic substrate preference and network context contribute to substrate selection of classical tyrosine phosphatases ', Journal of Biological Chemistry, vol. 292, no. 12, pp. 4942-4958 . https://doi.org/10.1074/jbc.M116.757518

مصطلحات موضوعية: Phosphopeptides, 0301 basic medicine, trapping mutants, Protein Conformation, substrate specificity, Phosphatase, tyrosine-protein phosphatase (tyrosine phosphatase), bayesian integration, peptide array, protein-protein interaction, recognition specificity, systems biology, Context (language use), Biology, Models, Biological, Biochemistry, Protein–protein interaction, 03 medical and health sciences, chemistry.chemical_compound, Protein Domains, Interaction network, Humans, Amino Acid Sequence, Protein Interaction Maps, Phosphorylation, Molecular Biology, Binding Sites, Kinase, Phosphopeptide, Substrate (chemistry), Bayes Theorem, Tyrosine phosphorylation, Cell Biology, Molecular Docking Simulation, Settore BIO/18 - Genetica, 030104 developmental biology, chemistry, Protein Tyrosine Phosphatases, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39c9dde45eaf3947fbaf9033323a41c
https://research.vu.nl/en/publications/68e81ddb-dab5-4bd0-b869-3be55091bcde