المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/journal_contribution/Sequences_of_primers_used_in_qRT-PCR_assay_/14217429

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.s010

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/RNF111_regulates_dsRNA-triggered_signaling_and_NF-_B_pathway_/14217411

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.s004

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/UBE2M_regulates_dsRNA-triggered_signaling_and_NF-_B_pathway_/14217405

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.s002

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Neddylation_positively_regulates_dsDNA-triggered_signaling_/14217402

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.s001

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Rnf168_did_not_influence_cGAS-STING_pathway_/14217414

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.s005

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Neddylation_increases_the_DNA_binding_ability_of_cGAS_/14217420

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.s007

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Depletion_of_Ube2m_but_not_Ube2f_attenuates_dsDNA-induced_innate_immune_response_/14217435

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.g002

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Ube2f_does_not_influence_anti-HSV-1_immunity_/14217423

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.s008

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Identification_of_cGAS_neddylation_sites_/14217417

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.s006

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Neddylation_facilitates_the_DNA-triggered_signaling_pathway_/14217432

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.g001

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/dataset/Mass_spectrometry_data_for_cGAS_neddylation_/14217426

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.s009

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Rnf111_facilitates_dsDNA-triggered_signaling_/14217438

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.g003

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Models_of_RNF111-facilitated_neddylation_potentiated_the_activation_of_cGAS_/14217453

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.g008

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/UBE2M-RNF111_mediated_neddylation_pathway_is_indispensable_for_the_innate_defense_against_HSV-1_infection_/14217450

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.g007

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Molecular_characterization_of_cGAS_neddylation_/14217444

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.g005

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Rnf111_interacts_with_cGAS_/14217441

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.g004

المؤلفون: Chenhui Li (697156), Lele Zhang (388913), Dong Qian (419482), Mingxing Cheng (797495), Haiyang Hu (140624), Ze Hong (3821641), Ye Cui (2273386), Huansha Yu (540366), Quanyi Wang (296707), Juanjuan Zhu (598334), Wei Meng (505670), Jin-fu Xu (9441986), Yi Sun (118759), Peng Zhang (2071), Chen Wang (88408)

مصطلحات موضوعية: Microbiology, Cell Biology, Immunology, Science Policy, Mental Health, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, HSV, attenuated DNA-triggered cGAS activ., neddylation inhibitor MLN 4924, Rnf 111 deficiency mice, Nedd 8 E 2 enzyme Ube 2m, Nedd 8 E 3 ligase, neddylation modification, Blocking neddylation pathway, RNF 111-facilitated neddylation pot., Nedd 8 E 3 ligase Rnf 111, cGAS-STING pathway activation, cytosolic DNA sensor cyclic GMP-AMP, Ube 2m neddylation axis, response, Rnf 111 interacted

Relation: https://figshare.com/articles/figure/Neddylation_promotes_the_activation_of_cGAS_/14217447

الاتاحة: https://doi.org/10.1371/journal.ppat.1009401.g006