المؤلفون: Nathaniel D. Anderson, Yael Babichev, Fabio Fuligni, Federico Comitani, Mehdi Layeghifard, Rosemarie E. Venier, Stefan C. Dentro, Anant Maheshwari, Sheena Guram, Claire Wunker, J. Drew Thompson, Kyoko E. Yuki, Huayun Hou, Matthew Zatzman, Nicholas Light, Marcus Q. Bernardini, Jay S. Wunder, Irene L. Andrulis, Peter Ferguson, Albiruni R. Abdul Razak, Carol J. Swallow, James J. Dowling, Rima S. Al-Awar, Richard Marcellus, Marjan Rouzbahman, Moritz Gerstung, Daniel Durocher, Ludmil B. Alexandrov, Brendan C. Dickson, Rebecca A. Gladdy, Adam Shlien

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c08bf52065ac4dcd90672db6a2810128

المؤلفون: Chuan Shih, Michal Vieth, Chafiq Hamdouchi, Boyu Zhong, Rima S. Al-awar, John H. Grimes

المصدر: Tetrahedron Letters. 47:2161-2164

مصطلحات موضوعية: Thiocyanate, Organic Chemistry, General Medicine, Combinatorial chemistry, Biochemistry, Toluene, chemistry.chemical_compound, chemistry, Silver thiocyanate, Yield (chemistry), Drug Discovery, Isothiocyanate, Organic chemistry, Reactivity (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234f337ced692197c6bcabad39062baa
https://doi.org/10.1016/j.tetlet.2006.01.119

المؤلفون: Thomas H. Corbett, Jian Liang, Rima S. Al-awar, Lisa Polin, David A. Hay, Chuan Shih, James Abraham Aikins, Vasu Vasudevan, Richard E. Moore, Lowell Lee Gibson, Juiwanna Kushner, Kathryn White, James Edward Ray, Michael J. Martinelli, Eric D. Moher, Susan Pugh, Varie David Lee, Tony Y. Zhang, Chiab Simpson, John E. Munroe

المصدر: Investigational New Drugs. 23:213-224

مصطلحات موضوعية: Chlorohydrins, Pancreatic ductal adenocarcinoma, Antineoplastic Agents, Mice, SCID, Pharmacology, Peptides, Cyclic, Mice, Structure-Activity Relationship, Depsipeptides, Animals, Humans, Structure–activity relationship, Pharmacology (medical), Antitumor activity, Mice, Inbred BALB C, Mice, Inbred ICR, Chemistry, Esters, Neoplasms, Experimental, Multiple drug resistance, Oncology, Cryptophycin, Epoxy Compounds, Drug Screening Assays, Antitumor, Neoplasm Transplantation, Human colon, Cryptophycins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc11771b8b45636496b48fe4a3174d8
https://doi.org/10.1007/s10637-005-6729-9

المؤلفون: James Edward Ray, Harold B. Brooks, Faming Zhang, Stanley P. Kolis, Kevin A. Sullivan, Kyle Andrew Hecker, Margaret M. Faul, Scott A. Watkins, Chuan Shih, Jianping Huang, Sajan Joseph, Eileen L. Considine, Michael A. Carr, Rima S. Al-awar, Richard M. Schultz, Charles D. Spencer

المصدر: Bioorganic & Medicinal Chemistry Letters. 14:3925-3928

مصطلحات موضوعية: Models, Molecular, Indoles, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Indolocarbazole, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, CDC2-CDC28 Kinases, Carcinoma, medicine, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Aza Compounds, Binding Sites, Molecular Structure, biology, Kinase, Chemistry, Cell Cycle, Cyclin-Dependent Kinase 2, Organic Chemistry, Biological activity, medicine.disease, Enzyme, Enzyme inhibitor, Cell culture, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcf9bf28ee7f8e83607e6af755f3725
https://doi.org/10.1016/j.bmcl.2004.05.088

المؤلفون: Sajan Joseph, Chuan Shih, Kyle Andrew Hecker, Richard M. Schultz, Bharvin K. R. Patel, John L. Grutsch, James Edward Ray, Eileen L. Considine, Charles D. Spencer, Kevin A. Sullivan, Rima S. Al-awar, Margaret M. Faul, Scott A. Watkins, Catherine A. Ogg, Harold B. Brooks, Nancy B. Stamm, Philip Parker Waid, Stanley P. Kolis, Jianping Huang

المصدر: Bioorganic & Medicinal Chemistry Letters. 14:3217-3220

مصطلحات موضوعية: chemistry.chemical_classification, Indoles, Chemistry, Kinase, Organic Chemistry, Clinical Biochemistry, Carbazoles, Cyclin-Dependent Kinase 4, Pharmaceutical Science, Biological activity, Inhibitory postsynaptic potential, Biochemistry, Chemical synthesis, Cyclin-Dependent Kinases, Enzyme, Cell culture, Proto-Oncogene Proteins, Drug Discovery, Molecular Medicine, Cyclin D1, Signal transduction, Protein kinase A, Protein Kinase Inhibitors, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456ac3a058024210c3686fd7b2326609
https://doi.org/10.1016/j.bmcl.2004.03.105

المؤلفون: Rima S. Al-awar, Michael E. LeTourneau, Marcella T. Clayton, Steven Wayne Pedersen, D. Scott Coffey, James Edward Ray, Thomas A. Engler, Sushant Malhotra, John L. Grutsch, Michael John Martinelli, Joseph Matthew Pawlak, Stanley P. Kolis, Kevin A. Sullivan, Margaret M. Faul, Kelly Wayne Furness

المصدر: The Journal of Organic Chemistry. 69:2967-2975

مصطلحات موضوعية: Indoles, Photochemistry, Stereochemistry, Carbazoles, Antineoplastic Agents, Acetates, Chemical synthesis, Maleimides, Structure-Activity Relationship, chemistry.chemical_compound, Cyclin D1, Polycyclic compound, Proto-Oncogene Proteins, Acetamides, Humans, Pyrroles, Enzyme Inhibitors, chemistry.chemical_classification, Aryl, Organic Chemistry, Cyclin-Dependent Kinase 4, Oxidants, Cyclin-Dependent Kinases, chemistry, Acetamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37eb9dd72e993b68b945c14cc7332a64
https://doi.org/10.1021/jo035606v

المؤلفون: Richard M. Schultz, Joseph H. Kennedy, Rima S. Al-Awar, Gottumukkala V. Subbaraju, Jian Liang, Thomas H. Corbett, Richard E. Moore, James E. Ray, Sherri L. Andis, Trimurtulu Golakoti

المصدر: Journal of Medicinal Chemistry. 46:2985-3007

مصطلحات موضوعية: Male, Lactams, Stereochemistry, Antineoplastic Agents, Adenocarcinoma, Chemical synthesis, Cryptophycin 52, Lactones, Mice, Structure-Activity Relationship, Depsipeptides, Drug Discovery, Tumor Cells, Cultured, Animals, Humans, Structure–activity relationship, chemistry.chemical_classification, Antimicrotubule agent, Cyclic peptide, Pancreatic Neoplasms, chemistry, Cryptophycin, Wittig reaction, Molecular Medicine, Drug Screening Assays, Antitumor, Neoplasm Transplantation, Lactone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea75cbc5fbe1eec811d06b06b062daf
https://doi.org/10.1021/jm0203884

المؤلفون: D. H. Lamunyon, Sajan Joseph, Daniel L. Comins, Rima S. Al-awar, Maria Guerra-Weltzien, Christopher J. Foti, Yuemei Zhang, Xinghai Chen, H. Hong

المصدر: Pure and Applied Chemistry. 69:477-482

مصطلحات موضوعية: Chemistry, General Chemical Engineering, Enantioselective synthesis, Organic chemistry, General Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::351528b1f683b760c2c92a2b8e0a09d0
https://doi.org/10.1351/pac199769030477

المؤلفون: Doris Tang, Rima S. Al-awar, Pandiaraju Subramanian, M. Monzur Morshed, Iain D. G. Watson, Matthäus Getlik, Brian J. Wilson

المصدر: ChemInform. 44

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Nucleophilic aromatic substitution, Rearrangement reaction, General Medicine, Halo, Triethylamine, Medicinal chemistry, Acetamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6a925814f0fcf09c1b63b4ca709296d9
https://doi.org/10.1002/chin.201341164

المؤلفون: Doris Tang, Matthäus Getlik, Rima S. Al-awar, M. Monzur Morshed, Pandiaraju Subramanian, Iain D. G. Watson, Brian J. Wilson

المصدر: The Journal of organic chemistry. 78(11)

مصطلحات موضوعية: Substitution reaction, Models, Molecular, Radical-nucleophilic aromatic substitution, Molecular Structure, Stereochemistry, Pyridines, Organic Chemistry, Crystallography, X-Ray, Medicinal chemistry, chemistry.chemical_compound, chemistry, Nucleophilic aromatic substitution, Acetamides, Nucleophilic substitution, Ethylamines, Hydrocarbons, Chlorinated, Molecule, Rearrangement reaction, Triethylamine, Acetamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6ff095e4f219cf3602b8819df2623a
https://pubmed.ncbi.nlm.nih.gov/23700973

المؤلفون: Rima S. Al-awar, Daniel L. Comins

المصدر: The Journal of Organic Chemistry. 60:711-716

مصطلحات موضوعية: Chemistry, Organic Chemistry, Organic chemistry, Lycopodium alkaloid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6320c7ecc87e1bce12a06aa72c434109
https://doi.org/10.1021/jo00108a039

المؤلفون: Daniel L. Comins, Sajan P. Joseph, Rima S. Al-awar

المصدر: The Journal of Organic Chemistry. 58:7732-7739

مصطلحات موضوعية: chemistry.chemical_compound, Lupinine, chemistry, Coniine, Bicyclic molecule, Reagent, Organic Chemistry, Pyridine, Piperidine, Enantiomer, Medicinal chemistry, Quinolizidines

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3df697960fde0aa38709040cecdad8c7
https://doi.org/10.1021/jo00079a018

المؤلفون: Adam H. Libby, Rima S. Al-awar, Daniel L. Comins, Bradley H. Wolfe, Christopher J. Foti

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Molecular Structure, Stereochemistry, Organic Chemistry, Enantioselective synthesis, Absolute configuration, Molecular Conformation, Stereoisomerism, Chemical synthesis, Article, Stereocenter, chemistry.chemical_compound, Acetic acid, Alkaloids, chemistry, Pyridine, Organic chemistry, Cyanogen bromide, Indicators and Reagents, Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293ed8ef583236baad71414936d00246
https://europepmc.org/articles/PMC3006060/

المؤلفون: Rima S. Al-awar, Daniel L. Comins, J. P. Joseph

المصدر: ChemInform. 24

مصطلحات موضوعية: Chemistry, Reagent, General Medicine, Medicinal chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::14304109763d3d2af533b0cae8b6745a
https://doi.org/10.1002/chin.199318219

المؤلفون: Daniel L. Comins, Rima S. Al-awar, Sajan P. Joseph

المصدر: ChemInform. 25

مصطلحات موضوعية: Lupinine, chemistry.chemical_compound, chemistry, Coniine, Reagent, Yield (chemistry), Pyridine, Organic chemistry, General Medicine, Piperidine, Quinolizidines, Methyl group

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::478f8cd8392eb7cfad1c3c6c1a5a56d9
https://doi.org/10.1002/chin.199420177

المؤلفون: Rima S. Al-awar, Christopher J. Foti, Daniel L. Comins, Adam H. Libby

المصدر: ChemInform. 30

مصطلحات موضوعية: Stereochemistry, Chemistry, Enantioselective synthesis, Organic chemistry, General Medicine, Lycopodium alkaloid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cf8221b6803b2479f6886e4623c542f9
https://doi.org/10.1002/chin.199931247

المؤلفون: Clinton A. Brooks, R. Richard Goehring, Rima S. Al-awar, Daniel L. Comins

المصدر: ChemInform. 30

مصطلحات موضوعية: Lycopodium, biology, Chemistry, Stereochemistry, Luciduline, Enantioselective synthesis, Organic chemistry, General Medicine, biology.organism_classification

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::81335e137e5013f9d637617b345ddeba
https://doi.org/10.1002/chin.199942235

المؤلفون: Rima S. Al-awar, Sajan P. Joseph, Daniel L. Comins

المصدر: Tetrahedron Letters. 33:7635-7638

مصطلحات موضوعية: Chemistry, Reagent, Organic Chemistry, Drug Discovery, Enantioselective synthesis, Organic chemistry, One-Step, Enantiomer, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ba6a5f9b620f42453382a67644c57761
https://doi.org/10.1016/0040-4039(93)88003-2

المؤلفون: Daniel L. Comins, Rima S. Al-awar

المصدر: The Journal of Organic Chemistry. 57:4098-4103

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Bicyclic molecule, Intramolecular reaction, Intramolecular force, Organic Chemistry, Organic chemistry, Ring (chemistry), Mannich reaction, Reversible reaction, Ene reaction, Benzyl chloroformate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4642caf8a54006fde0c019fc5536e115
https://doi.org/10.1021/jo00041a011

المؤلفون: Rima S. Al-awar, S. O’Connor, Daniel L. Comins

مصطلحات موضوعية: chemistry.chemical_compound, Nucleophile, chemistry, Nitrene, Heteroatom, Halogenation, Diazo, Pyridinium, Alkylation, Ring (chemistry), Medicinal chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c832f19480b72526cafe8beae8a35368
https://doi.org/10.1016/b978-008044992-0.00602-7