نتائج البحث - "Richter, Wolfgang F."

1

Academic Journal

Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies

المؤلفون: Stüber, Jakob C., Rechberger, Karin F., Miladinović, Saša M., Pöschinger, Thomas, Zimmermann, Tamara, Villenave, Remi, Eigenmann, Miro J., Kraft, Thomas E., Shah, Dhaval K., Kettenberger, Hubert, Richter, Wolfgang F.

المصدر: AAPS Open ; volume 8, issue 1 ; ISSN 2364-9534

الاتاحة: http://dx.doi.org/10.1186/s41120-021-00048-9
https://link.springer.com/content/pdf/10.1186/s41120-021-00048-9.pdf
https://link.springer.com/article/10.1186/s41120-021-00048-9/fulltext.html

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2

Academic Journal

Non-human primates in the PKPD evaluation of biologics: Needs and options to reduce, refine, and replace. A BioSafe White Paper

المؤلفون: Ménochet, Karelle, Yu, Hongbin, Wang, Bonnie, Tibbitts, Jay, Hsu, Cheng-Pang, Kamath, Amrita V., Richter, Wolfgang F., Baumann, Andreas

المساهمون: The author(s) reported there is no funding associated with the work featured in this article

المصدر: mAbs ; volume 14, issue 1 ; ISSN 1942-0862 1942-0870

الاتاحة: https://doi.org/10.1080/19420862.2022.2145997
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2022.2145997

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3

Academic Journal

Effect of variable domain charge on in vitro and in vivo disposition of monoclonal antibodies

المؤلفون: Liu, Shufang, Verma, Ashwni, Kettenberger, Hubert, Richter, Wolfgang F., Shah, Dhaval K.

المساهمون: associated

المصدر: mAbs ; volume 13, issue 1 ; ISSN 1942-0862 1942-0870

الاتاحة: http://dx.doi.org/10.1080/19420862.2021.1993769
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.1993769

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4

Academic Journal

Challenges of non-clinical safety testing for biologics: A Report of the 9th BioSafe European Annual General Membership Meeting

المؤلفون: Kissner, Thomas, Blaich, Guenter, Baumann, Andreas, Kronenberg, Sven, Hey, Adam, Kiessling, Andrea, Schmitt, Petra M., Driessen, Wouter, Carrez, Chantal, Kramer, Daniel, Fretland, Jennifer, Richter, Wolfgang F., Paehler, Tobias, Hopfer, Ulrike, Rattel, Benno

المصدر: mAbs ; volume 13, issue 1 ; ISSN 1942-0862 1942-0870

الاتاحة: http://dx.doi.org/10.1080/19420862.2021.1938796
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2021.1938796

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5

Academic Journal

Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody

المصدر: Nature Communications ; volume 11, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-020-16838-w
https://www.nature.com/articles/s41467-020-16838-w.pdf
https://www.nature.com/articles/s41467-020-16838-w

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6

Academic Journal

Heparin chromatography as an in vitro predictor for antibody clearance rate through pinocytosis

المؤلفون: Kraft, Thomas E., Richter, Wolfgang F., Emrich, Thomas, Knaupp, Alexander, Schuster, Michaela, Wolfert, Andreas, Kettenberger, Hubert

المصدر: mAbs ; volume 12, issue 1 ; ISSN 1942-0862 1942-0870

الاتاحة: http://dx.doi.org/10.1080/19420862.2019.1683432
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2019.1683432

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7

Academic Journal

Hematopoietic cells as site of first-pass catabolism after subcutaneous dosing and contributors to systemic clearance of a monoclonal antibody in mice

المؤلفون: Richter, Wolfgang F., Christianson, Gregory J., Frances, Nicolas, Grimm, Hans Peter, Proetzel, Gabriele, Roopenian, Derry C.

المصدر: mAbs ; volume 10, issue 5, page 803-813 ; ISSN 1942-0862 1942-0870

الاتاحة: http://dx.doi.org/10.1080/19420862.2018.1458808
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2018.1458808

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8

Academic Journal

Novel in Vivo and in Vitro Pharmacokinetic/Pharmacodynamic-Based Human Starting Dose Selection for Glofitamab

المؤلفون: Frances, Nicolas, Bacac, Marina, Bray-French, Katharine, Christen, François, Hinton, Heather, Husar, Elisabeth, Quackenbush, Elizabeth, Schäfer, Martin, Schick, Eginhard, Vyver, Arthur Van De, Richter, Wolfgang F.

المساهمون: F. Hoffmann-La Roche

المصدر: Journal of Pharmaceutical Sciences ; volume 111, issue 4, page 1208-1218 ; ISSN 0022-3549

الاتاحة: http://dx.doi.org/10.1016/j.xphs.2021.12.019
https://api.elsevier.com/content/article/PII:S0022354921006973?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0022354921006973?httpAccept=text/plain

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9

Additional file 2 of Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies

المؤلفون: St��ber, Jakob C., Rechberger, Karin F., Miladinovi��, Sa��a M., P��schinger, Thomas, Zimmermann, Tamara, Villenave, Remi, Eigenmann, Miro J., Kraft, Thomas E., Shah, Dhaval K., Kettenberger, Hubert, Richter, Wolfgang F.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfe00f039a2763d033c9b6d4229549b

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10

Additional file 4 of Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies

المؤلفون: St��ber, Jakob C., Rechberger, Karin F., Miladinovi��, Sa��a M., P��schinger, Thomas, Zimmermann, Tamara, Villenave, Remi, Eigenmann, Miro J., Kraft, Thomas E., Shah, Dhaval K., Kettenberger, Hubert, Richter, Wolfgang F.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6880d43b30be6b0a144f9987228c2710

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11

Additional file 1 of Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies

المؤلفون: St��ber, Jakob C., Rechberger, Karin F., Miladinovi��, Sa��a M., P��schinger, Thomas, Zimmermann, Tamara, Villenave, Remi, Eigenmann, Miro J., Kraft, Thomas E., Shah, Dhaval K., Kettenberger, Hubert, Richter, Wolfgang F.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cdfd308a6a09c1e543796d116e8e22

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12

Additional file 3 of Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies

المؤلفون: St��ber, Jakob C., Rechberger, Karin F., Miladinovi��, Sa��a M., P��schinger, Thomas, Zimmermann, Tamara, Villenave, Remi, Eigenmann, Miro J., Kraft, Thomas E., Shah, Dhaval K., Kettenberger, Hubert, Richter, Wolfgang F.

مصطلحات موضوعية: sense organs, skin and connective tissue diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7be88f4fd64c4606d8e2c823565ab3

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13

Academic Journal

Immunogenicity, Inflammation, and Lipid Accumulation in Cynomolgus Monkeys Infused with a Lipidated Tetranectin-ApoA-I Fusion Protein

المؤلفون: Regenass-Lechner, Franziska, Staack, Roland F., Mary, Jean-Luc, Richter, Wolfgang F., Winter, Michael, Jordan, Gregor, Justies, Nicole, Langenkamp, Anja, Garrido, Rosario, Albassam, Mudher, Singer, Thomas, Atzpodien, Elke-Astrid

المصدر: Toxicological Sciences ; volume 150, issue 2, page 378-389 ; ISSN 1096-6080 1096-0929

الاتاحة: http://dx.doi.org/10.1093/toxsci/kfw004
http://academic.oup.com/toxsci/article-pdf/150/2/378/16690255/kfw004.pdf

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14

Academic Journal

Neonatal Immune Tolerance Induction to Allow Long-Term Studies With an Immunogenic Therapeutic Monoclonal Antibody in Mice

المؤلفون: Piccand, Matthieu, Bessa, Juliana, Schick, Eginhard, Senn, Claudia, Bourquin, Carole, Richter, Wolfgang F.

المصدر: The AAPS Journal ; volume 18, issue 2, page 354-361 ; ISSN 1550-7416

الاتاحة: http://dx.doi.org/10.1208/s12248-015-9850-5
http://link.springer.com/content/pdf/10.1208/s12248-015-9850-5.pdf
http://link.springer.com/article/10.1208/s12248-015-9850-5/fulltext.html
http://link.springer.com/content/pdf/10.1208/s12248-015-9850-5

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15

Academic Journal

Nonclinical Development of Biologics: Integrating Safety, Pharmacokinetics, and Pharmacodynamics to Create Smarter and More Flexible Nonclinical Safety Programs Optimizing Animal Use

المؤلفون: Hey, Adam, Baumann, Andreas, Kronenberg, Sven, Blaich, Guenter, Mohl, Silke, Fagg, Rajni, Ulrich, Peter, Rattel, Benno, Richter, Wolfgang F., Kiessling, Andrea, Weir, Lucinda

المصدر: International Journal of Toxicology ; volume 40, issue 3, page 270-284 ; ISSN 1091-5818 1092-874X

الاتاحة: http://dx.doi.org/10.1177/1091581821994288
http://journals.sagepub.com/doi/pdf/10.1177/1091581821994288
http://journals.sagepub.com/doi/full-xml/10.1177/1091581821994288

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16

Academic Journal

Subcutaneous versus Intravenous Administration of Rituximab: Pharmacokinetics, CD20 Target Coverage and B-Cell Depletion in Cynomolgus Monkeys

المؤلفون: Mao, Cheng-Ping, Brovarney, Martin R., Dabbagh, Karim, Birnböck, Herbert F., Richter, Wolfgang F., Del Nagro, Christopher J.

المساهمون: Richards, Kristy L.

المصدر: PLoS ONE ; volume 8, issue 11, page e80533 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0080533
http://dx.plos.org/10.1371/journal.pone.0080533

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17

Academic Journal

Gantenerumab: A Novel Human Anti-Aβ Antibody Demonstrates Sustained Cerebral Amyloid-β Binding and Elicits Cell-Mediated Removal of Human Amyloid-β

المؤلفون: Bohrmann, Bernd, Baumann, Karlheinz, Benz, Jörg, Gerber, Francoise, Huber, Walter, Knoflach, Frédéric, Messer, Jürg, Oroszlan, Krisztina, Rauchenberger, Robert, Richter, Wolfgang F., Rothe, Christine, Urban, Margit, Bardroff, Michael, Winter, Michael, Nordstedt, Christer, Loetscher, Hansruedi

المصدر: Journal of Alzheimer's Disease ; volume 28, issue 1, page 49-69 ; ISSN 1875-8908 1387-2877

الاتاحة: https://doi.org/10.3233/jad-2011-110977
https://content.iospress.com/download?id=10.3233/JAD-2011-110977

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18

Academic Journal

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration

المصدر: mAbs ; volume 4, issue 2, page 243-255 ; ISSN 1942-0862 1942-0870

الاتاحة: http://dx.doi.org/10.4161/mabs.4.2.19387
http://www.tandfonline.com/doi/pdf/10.4161/mabs.4.2.19387

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19

Academic Journal

PKPD Assessment of the Anti-CD20 Antibody Obinutuzumab in Cynomolgus Monkey is Feasible Despite Marked Anti-Drug Antibody Response in This Species

المؤلفون: Grimm, Hans Peter, Schick, Eginhard, Hainzl, Dominik, Justies, Nicole, Yu, Li, Klein, Christian, Husar, Elisabeth, Richter, Wolfgang F.

المصدر: Journal of Pharmaceutical Sciences ; volume 108, issue 11, page 3729-3736 ; ISSN 0022-3549

الاتاحة: http://dx.doi.org/10.1016/j.xphs.2019.07.013
https://api.elsevier.com/content/article/PII:S0022354919304484?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0022354919304484?httpAccept=text/plain

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20

Academic Journal

High-Throughput, Sensitive LC-MS Quantification of Biotherapeutics and Biomarkers Using Antibody-Free, Peptide-Level, Multiple-Mechanism Enrichment via Strategic Regulation of pH and Ionic and Solvent Strengths

المؤلفون: An, Bo, Zhang, Ming, Pu, Jie, Shen, Shichen, Qu, Yang, Chen, Yuan-Ju, Huo, Shihan, Wang, Xue, Polli, Joseph Ryan, Balthasar, Joseph P., Herzog, Denis, Ferrari, Luca, Staack, Roland F., Richter, Wolfgang F., Otteneder, Michael B., Benincosa, Lisa J., Zhou, Shaolian, Vazvaei, Faye, Qu, Jun

المساهمون: Center of Protein Therapeutics Industrial Award, Department of Veterans Affairs I01, NIH CTSA award, NIH

المصدر: Analytical Chemistry ; volume 91, issue 5, page 3475-3483 ; ISSN 0003-2700 1520-6882

الاتاحة: http://dx.doi.org/10.1021/acs.analchem.8b05046
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.8b05046

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