المؤلفون: Andrew S.C. Rice, Kersti Karu, David L.H. Bennett, Ana Antunes-Martins, Benjamin Thomas, Min Fang, Richard S. Swanwick, William A. Foster, Eiji Yoshimi, Stephen B. McMahon, Amparo Novejarque-Gadea, Kenji Okuse

المساهمون: Wellcome Trust, Commission of the European Communities

المصدر: Journal of Proteome Research. 19:1592-1619

مصطلحات موضوعية: Proteomics, DORSAL-ROOT GANGLIA, 0301 basic medicine, Biochemistry, stable isotope dimethyl labeling, Rats, Sprague-Dawley, ACTIVATION, Tandem Mass Spectrometry, SYNAPTIC PLASTICITY, NEURONS, proteomic, mass spectrometry, biology, MEMBRANE-PROTEINS, Central nucleus of the amygdala, Chronic pain, PEPTIDES, amygdala, medicine.anatomical_structure, Nociception, DOUBLECORTIN, Neuropathic pain, 03 Chemical Sciences, Life Sciences & Biomedicine, EXPRESSION, Biochemistry & Molecular Biology, medicine.medical_specialty, Doublecortin Protein, Amygdala, Biochemical Research Methods, 03 medical and health sciences, Internal medicine, medicine, Animals, spinal nerve transection, LC-MS/MS, neuropathic pain, Science & Technology, 030102 biochemistry & molecular biology, business.industry, Central Amygdaloid Nucleus, MASS-SPECTROMETRY, General Chemistry, 06 Biological Sciences, medicine.disease, Spinal cord, Rats, Doublecortin, 030104 developmental biology, Endocrinology, Membrane protein, MARKER, biology.protein, Neuralgia, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a03f7bd04099345bd0aa299a27fd994
https://doi.org/10.1021/acs.jproteome.9b00805

المؤلفون: Richard S. Swanwick, Rudolf Konrad Allemann, E. Joel Loveridge, Lai-Hock Tey, Sabine L. Flitsch

المصدر: FEBS Journal. 277:2171-2179

مصطلحات موضوعية: chemistry.chemical_classification, Glycosylation, biology, Mutant, Mutagenesis, Cell Biology, Biochemistry, chemistry.chemical_compound, Enzyme, chemistry, Dihydrofolate reductase, biology.protein, Denaturation (biochemistry), Protein folding, Molecular Biology, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::51a50fda35cc2f253d1fd3f8050528ed
https://doi.org/10.1111/j.1742-4658.2010.07634.x

المؤلفون: Richard S. Swanwick, Rudolf Konrad Allemann, E. Joel Loveridge, Robert J. Rodriguez

المصدر: Biochemistry. 48:5922-5933

مصطلحات موضوعية: Anions, Protein Conformation, Stereochemistry, Dimer, Biochemistry, Catalysis, chemistry.chemical_compound, Enzyme Stability, Dihydrofolate reductase, Thermotoga maritima, chemistry.chemical_classification, biology, Thermophile, Genetic Variation, biology.organism_classification, Hyperthermophile, Tetrahydrofolate Dehydrogenase, Crystallography, Enzyme, Monomer, Amino Acid Substitution, chemistry, Mutation, Mutagenesis, Site-Directed, biology.protein, bacteria, Protein Multimerization, Hydrophobic and Hydrophilic Interactions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035d9aa52f718a602356c88ce9954cb1
https://doi.org/10.1021/bi900411a

المؤلفون: Rudolf Konrad Allemann, Lai-Hock Tey, Sabine L. Flitsch, Alison M. Daines, Richard S. Swanwick

المصدر: ChemBioChem. 6:1338-1340

مصطلحات موضوعية: Models, Molecular, Thermal denaturation, Glycosylation, Hot Temperature, Stereochemistry, Biochemistry, chemistry.chemical_compound, Enzyme Stability, Dihydrofolate reductase, Escherichia coli, Native state, Thermal stability, Molecular Biology, chemistry.chemical_classification, Binding Sites, biology, Chemistry, Circular Dichroism, fungi, Organic Chemistry, Mutagenesis, food and beverages, Protein Structure, Tertiary, Tetrahydrofolate Dehydrogenase, Enzyme, Mutation, biology.protein, Molecular Medicine, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf92d007103f41534151091abfe059c
https://doi.org/10.1002/cbic.200500103

المؤلفون: Ya-Chun, Chen, Alessandro, Pristerá, Mahmood, Ayub, Richard S, Swanwick, Kersti, Karu, Yosuke, Hamada, Andrew S C, Rice, Kenji, Okuse

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Receptors, Neuropeptide, Neurons, Membrane Glycoproteins, Sensory Receptor Cells, Macrophages, Neuropeptides, Calcium Intracellular Release, Pain, VGF, Mass Spectrometry, Peptide Fragments, Rats, Receptors, Complement, Mice, Neuropeptide, Neurobiology, gC1qR, Animals, Humans, Neuralgia, Calcium, Sensory Neurons, Microglia, Neuropathic Pain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f615f3df167d38ea14ecc610ec75ed95
https://pubmed.ncbi.nlm.nih.gov/24106277

المؤلفون: Lai-Hock, Tey, E Joel, Loveridge, Richard S, Swanwick, Sabine L, Flitsch, Rudolf K, Allemann

المصدر: The FEBS journal. 277(9)

مصطلحات موضوعية: Models, Molecular, Protein Denaturation, Protein Folding, Glycosylation, Circular Dichroism, Ligands, Protein Structure, Tertiary, Kinetics, Tetrahydrofolate Dehydrogenase, Enzyme Stability, Mutation, Biocatalysis, Escherichia coli, Unfolded Protein Response

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::28443a780579a1f7010c4546fd5f4dca
https://pubmed.ncbi.nlm.nih.gov/20412060

المؤلفون: Paul J. Shrimpton, Rudolf Konrad Allemann, Richard S. Swanwick, Jiayun Pang, Giovanni Maglia, Robert J. Rodriguez, Rhiannon M. Evans, Lai-Hock Tey

المصدر: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 361(1472)

مصطلحات موضوعية: Models, Molecular, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Catalysis, Enzyme catalysis, Evolution, Molecular, Bacterial Proteins, Species Specificity, Dihydrofolate reductase, medicine, Escherichia coli, chemistry.chemical_classification, biology, Protein dynamics, Temperature, Active site, biology.organism_classification, Kinetics, Tetrahydrofolate Dehydrogenase, Enzyme, chemistry, Biochemistry, Thermotoga maritima, Mutation, biology.protein, General Agricultural and Biological Sciences, Hydrogen, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29dd90d5fbf10cb50ce229222d9e32b1
https://pubmed.ncbi.nlm.nih.gov/16873119

المؤلفون: Richard S. Swanwick, Rudolf Konrad Allemann, Giovanni Maglia, Lai-Hock Tey

المصدر: The Biochemical journal. 394(Pt 1)

مصطلحات موضوعية: Models, Molecular, Hydrogen, Protein Conformation, Movement, chemistry.chemical_element, mechanism, transfer rates, Photochemistry, Biochemistry, enzyme catalysis, active-site, Catalysis, Enzyme catalysis, tunnelling, dihydrofolate reductase, hydride transfer, Dihydrofolate reductase, Kinetic isotope effect, hydrogen transfer, Escherichia coli, protein motions, Molecular Biology, soybean lipoxygenase-1, biology, Chemistry, Hydride, Temperature, Active site, loop, Cell Biology, dynamics, Hydrogen-Ion Concentration, promoting vibration, flexibility, Kinetics, Tetrahydrofolate Dehydrogenase, Deuterium, kinetics, biology.protein, Research Article

وصف الملف: Print; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cff9bc22ff45148a6560d93d6a9bf67
https://pubmed.ncbi.nlm.nih.gov/16241906

المؤلفون: Sabine L. Flitsch, Rudolf Konrad Allemann, Alison M. Daines, Richard S. Swanwick

المصدر: Organicbiomolecular chemistry. 3(4)

مصطلحات موضوعية: chemistry.chemical_classification, Glycosylation, Molecular Structure, Chemistry, Organic Chemistry, Carbohydrates, Biochemistry, Combinatorial chemistry, Peptide Fragments, chemistry.chemical_compound, Tetrahydrofolate Dehydrogenase, Yield (chemistry), Ethyl Methanesulfonate, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Escherichia coli, Mutagenesis, Site-Directed, Organic chemistry, Glycosyl, Cysteine, Physical and Theoretical Chemistry, Site-directed mutagenesis, Glycoprotein, Glycoproteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf78814e4b9bb19f32c06b77d081879c
https://pubmed.ncbi.nlm.nih.gov/15703788

المؤلفون: Enas M. Behiry, Edric Joel Loveridge, Richard S. Swanwick, Rudolf Konrad Allemann

المصدر: Journal of the American Chemical Society. 131:6926-6927

مصطلحات موضوعية: Models, Molecular, chemistry.chemical_classification, biology, Concerted reaction, Stereochemistry, Thermophile, Active site, Substrate (chemistry), General Chemistry, Hydrogen-Ion Concentration, biology.organism_classification, Biochemistry, Catalysis, Kinetics, Tetrahydrofolate Dehydrogenase, Colloid and Surface Chemistry, Enzyme, Bacterial Proteins, chemistry, Thermotoga maritima, Escherichia coli, biology.protein, Protein quaternary structure, Thermostability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1442b93e34ba1b2dcfef75bf9f5718
https://doi.org/10.1021/ja901441k

المؤلفون: Rudolf K. Allemann, Rhiannon M. Evans, Lai-hock Tey, Giovanni Maglia, Jiayun Pang, Robert Rodriguez, Paul J. Shrimpton, Richard S. Swanwick

المصدر: Philosophical Transactions of the Royal Society B: Biological Sciences; Aug2006, Vol. 361 Issue 1472, p1317-1321, 5p

المؤلفون: Kenji Okuse, Alessandro Pristerà, Richard S. Swanwick

المصدر: Neuroscience Letters

مصطلحات موضوعية: Neuroscience(all), Central nervous system, Pain, Sensory system, Nerve Tissue Proteins, Review, Endoplasmic Reticulum, Dinoprostone, Sodium Channels, NAV1.8 Voltage-Gated Sodium Channel, Mice, Contactins, medicine, Animals, Humans, Sensory Neuron, Annexin A2, Trafficking, business.industry, Mechanism (biology), General Neuroscience, Sodium channel, Cell Membrane, S100 Proteins, Chronic pain, medicine.disease, Sensory neuron, Adaptor Proteins, Vesicular Transport, Protein Subunits, Protein Transport, Nociception, medicine.anatomical_structure, business, Sodium Channel, Neuroscience, Cell Adhesion Molecules

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3175c2ddaa8068769ae6084031a8d318

المؤلفون: Richard S. Swanwick, Alison M. Daines, Lai-Hock Tey, Sabine L. Flitsch, Rudolf K. Allemann

المصدر: ChemBioChem; Sep2005, Vol. 6 Issue 8, p1338-1340, 3p