المؤلفون: Josh Smith, Felipe Guapo, Lisa Strasser, Silvia Millán-Martín, Steven G. Milian, Richard O. Snyder, Jonathan Bones

مصطلحات موضوعية: Genetics, Molecular Biology, Biotechnology, Sociology, Immunology, Developmental Biology, Inorganic Chemistry, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, mobile phase modifier, identity testing platform, gene therapy targets, evaluate product quality, data processing methods, critical attribute monitored, compliant software capable, intact separations platform, reliable serotype identification, lc – ms, confirm ptms identified, aav capsid proteins, depth ptm characterization, intact vp analysis, intact separation, depth characterization, translational modifications, regulatory setting, rapid identification, rapid adeno

Relation: https://figshare.com/articles/journal_contribution/Development_of_a_Rapid_Adeno-Associated_Virus_AAV_Identity_Testing_Platform_through_Comprehensive_Intact_Mass_Analysis_of_Full-Length_AAV_Capsid_Proteins/24882345

الاتاحة: https://doi.org/10.1021/acs.jproteome.3c00513.s001
https://figshare.com/articles/journal_contribution/Development_of_a_Rapid_Adeno-Associated_Virus_AAV_Identity_Testing_Platform_through_Comprehensive_Intact_Mass_Analysis_of_Full-Length_AAV_Capsid_Proteins/24882345

المؤلفون: Susan D'Costa, Veronique Blouin, Frederic Broucque, Magalie Penaud-Budloo, Achille Fçranois, Irene C Perez, Christine Le Bec, Philippe Moullier, Richard O Snyder, Eduard Ayuso

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)

مصطلحات موضوعية: Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050116301607; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/abdbfb21a81743f3b6a2cf91a09b3f39

المؤلفون: Jean-Baptiste Dupont, Benoit Tournaire, Christophe Georger, Béatrice Marolleau, Laurence Jeanson-Leh, Mireille Ledevin, Pierre Lindenbaum, Emilie Lecomte, Benjamin Cogné, Laurence Dubreil, Thibaut Larcher, Bernard Gjata, Laetitia Van Wittenberghe, Caroline Le Guiner, Magalie Penaud-Budloo, Richard O Snyder, Philippe Moullier, Adrien Léger

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)

مصطلحات موضوعية: Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050116300225; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/846a902b7ddb4553bb393762ce9f0d6f

المؤلفون: Kristina Fredriksen, Charles B. Berde, Jai Vaze, Susan E. Waisbren, Lauren E. Black, Christelle Moufawad El Achkar, Julie Douville, Bobbie L. Riley, Jaejoon Choi, Alan H. Beggs, Pankaj B. Agrawal, Iva Stojkovska, Stephen Chu, Nandkishore R. Belur, Austin Larson, David K. Urion, Renata L. DiDonato, Richard O. Snyder, Emily Berry, Eunjung Lee, Al Patterson, Kelly A. Pflock, Brenda Barton, Sara F. Goldkind, Jinkuk Kim, Laura Cornelissen, Timothy W. Yu, P. Ellen Grant, Mary K. Pendergast, Chunguang Hu, Benjamin D. Goodlett, Lucinda Williams, Aubrie Soucy, Kimberly Tyndall, Myriam Armant, Erika F. Augustine, Olaf Bodamer, Ashley Kuniholm, Luis M. Pereira, Chantal Reed, Alessandra Biffi, Kira A. Dies, Amy Pasternak, Casie A. Genetti, Annapurna Poduri, Alla V. Tsytsykova, Joseph R. Mazzulli, Peter J. Park

المصدر: N Engl J Med

مصطلحات موضوعية: First contact, Biopsy, Investigational, Messenger, Oligonucleotides, Disease, Neuropsychological Tests, 030204 cardiovascular system & hematology, Bioinformatics, Article, 03 medical and health sciences, Child Development, Rare Diseases, 0302 clinical medicine, Neuronal Ceroid-Lipofuscinoses, Seizures, Insertional, Drug Discovery, Humans, Medicine, RNA, Messenger, 030212 general & internal medicine, Antisense, Precision Medicine, Child, Adverse effect, Skin pathology, Skin, Whole Genome Sequencing, Extramural, business.industry, Oligonucleotide, Drugs, Membrane Transport Proteins, Electroencephalography, Drugs, Investigational, General Medicine, Oligonucleotides, Antisense, Precision medicine, Mutagenesis, Insertional, Mutagenesis, Antisense oligonucleotides, RNA, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19381104d0ffe14b9de184a4638dda48
https://doi.org/10.1530/ey.17.14.8

المؤلفون: Weiyi Ni, Caroline Le Guiner, Philippe Moullier, Richard O Snyder

المصدر: PLoS ONE, Vol 7, Iss 5, p e36461 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3343023?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/fbc2c7feb7d544b8918c07d6a34d0cbf

المؤلفون: Adrien Léger, Caroline Le Guiner, Michael L Nickerson, Kate McGee Im, Nicolas Ferry, Philippe Moullier, Richard O Snyder, Magalie Penaud-Budloo

المصدر: PLoS ONE, Vol 6, Iss 6, p e20881 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3110818?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/dce465869f324f5f90b1718ab716eb4b

المؤلفون: Richard O. Snyder, Christof Von Kalle, Fabienne Rolling, Alice Toromanoff, Yan Chérel, Pierre Chenuaud, Magalie Penaud-budloo, Caroline Le Guiner, Ali Nowrouzi

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jvi.asm.org/content/82/16/7875.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.530.4953; http://jvi.asm.org/content/82/16/7875.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.530.4953
http://jvi.asm.org/content/82/16/7875.full.pdf

المؤلفون: Kim Van Vliet, Veronique Blouin, Mavis Agb, Richard O. Snyder

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://msg.mbi.ufl.edu/papers/2006/vliet1.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.386.4265; http://msg.mbi.ufl.edu/papers/2006/vliet1.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.386.4265
http://msg.mbi.ufl.edu/papers/2006/vliet1.pdf

المؤلفون: Richard O. Snyder, Robert M. Kotin

المصدر: Human Gene Therapy. 28:350-360

مصطلحات موضوعية: 0301 basic medicine, viruses, Genetic Vectors, Gene transfer, Computational biology, Biology, medicine.disease_cause, Cell Line, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, Genetics, medicine, Animals, Humans, Vector (molecular biology), Molecular Biology, Adeno-associated virus, business.industry, Clinical grade, Genetic Therapy, Dependovirus, Invertebrates, Biotechnology, Clinical trial, Alipogene tiparvovec, 030104 developmental biology, Cell culture, 030220 oncology & carcinogenesis, Recombinant DNA, Molecular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc23ff6357c17d104d2919db0afdcd8a
https://doi.org/10.1089/hum.2017.042

المؤلفون: Carol H. Miao, Hiroyuki Nakai, Arthur R. Thompson, Theresa A. Storm, Winnie Chiu, Richard O. Snyder, Mark A. Kay

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://kaylab.stanford.edu/manuscripts/JV-4-2000-MIAO-ETAL.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.325.8599; http://kaylab.stanford.edu/manuscripts/JV-4-2000-MIAO-ETAL.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.325.8599
http://kaylab.stanford.edu/manuscripts/JV-4-2000-MIAO-ETAL.pdf

المؤلفون: A. Storm, Winnie Chiu, Richard O. Snyder, Mark A. Kay, Carol H. Miao, Hiroyuki Nakai, Arthur R. Thompson, Nonrandom Transduction Of Recombinant

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jvi.asm.org/content/74/8/3793.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.539.2040; http://jvi.asm.org/content/74/8/3793.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.539.2040
http://jvi.asm.org/content/74/8/3793.full.pdf

المؤلفون: Delphine Bohl, Catherine Lagarde, Nathalie Vincent-lacaze, Richard O. Snyder

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jvi.asm.org/content/73/3/1949.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.613.3739; http://jvi.asm.org/content/73/3/1949.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.613.3739
http://jvi.asm.org/content/73/3/1949.full.pdf

المؤلفون: Frédéric Broucque, Magalie Penaud-Budloo, Katell Harrouet, Susan M. D'Costa, Mohammed Bouzelha, Martin Lock, Richard O. Snyder, Véronique Blouin, Sandy Douthe, Eduard Ayuso, Sylvie Saleun, Oumeya Adjali, Sushma Ogram

المساهمون: Laboratoire de Thérapie Génique Translationnelle des Maladies Génétiques (Inserm UMR 1089), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), Brammer Bio [Alachua, FL, USA], Department of Pathology and Laboratory Medicine [Philadelphia, PA, USA] (Perelman School of Medicine), University of Pennsylvania [Philadelphia], Financial support to E.A.’s laboratory was provided by INSERM, University of Nantes, CHU of Nantes, Fondation d’Entreprises pour la Thérapie Génique en Pays de la Loire, and Région Pays de la Loire and Pre-industrial gene therapy consortium (Agence Nationale de la Recherche - Investissements d’Avenir, grant number 10-DPBS-0001)., ANR-10-DPBS-0001,PGT,Consortium préindustriel des vecteurs de thérapie génique(2010), University of Pennsylvania, JAULIN, Nicolas, Démonstrateurs - Consortium préindustriel des vecteurs de thérapie génique - - PGT2010 - ANR-10-DPBS-0001 - DPBS - VALID

المصدر: Gene Therapy
Gene Therapy, Nature Publishing Group, 2019, 26 (5), pp.211-215. ⟨10.1038/s41434-019-0072-9⟩
Gene Therapy, 2019, 26 (5), pp.211-215. ⟨10.1038/s41434-019-0072-9⟩

مصطلحات موضوعية: 0301 basic medicine, Serotype, [SDV]Life Sciences [q-bio], Genetic Vectors, Biology, medicine.disease_cause, Virus Replication, Virus, 03 medical and health sciences, 0302 clinical medicine, Genetics, medicine, Humans, Dosing, Vector (molecular biology), Molecular Biology, Reference standards, Adeno-associated virus, Cryopreservation, Protein Stability, Dependovirus, Reference Standards, Virology, 3. Good health, [SDV] Life Sciences [q-bio], Titer, 030104 developmental biology, HEK293 Cells, Capsid, 030220 oncology & carcinogenesis, Practice Guidelines as Topic, Molecular Medicine, Capsid Proteins

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49e95058cd6bf8be45d9f3a3b6458b9
https://pubmed.ncbi.nlm.nih.gov/30926961

المؤلفون: Adrien Leger, Bernard Gjata, Benjamin Cogné, Laetitia van Wittenberghe, Benoît Tournaire, Jean-Baptiste Dupont, Alban Vignaud, Christophe Georger, Romain Durand, Béatrice Marolleau, Richard O. Snyder, Emilie Bertil, Emilie Lecomte, Philippe Moullier

المصدر: Les Cahiers de Myologie. :99-101

مصطلحات موضوعية: business.industry, Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9574439f8c92f990f0c38edea2d7f9c2
https://doi.org/10.1051/myolog/201613021

المؤلفون: Weiyi Ni, Philippe Moullier, Irene C. Perez, Richard O. Snyder, Caroline Le Guiner, Jennifer Lyles

المصدر: Analytical and Bioanalytical Chemistry. 405:9641-9653

مصطلحات موضوعية: Doping in Sports, biology, Athletes, Computer science, Genetic Vectors, Gene Transfer Techniques, Gene transfer, Performance-Enhancing Substances, Computational biology, biology.organism_classification, Polymerase Chain Reaction, Biochemistry, Molecular biology, Analytical Chemistry, Real-time polymerase chain reaction, Gene doping, Complementary DNA, TaqMan, Humans, Vector (molecular biology), human activities, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624a8c393f5cc1e253838459c4de688f
https://doi.org/10.1007/s00216-013-7264-8

المؤلفون: Philippe Moullier, Irene C. Perez, Frédéric Broucque, Christine Le Bec, Eduard Ayuso, Achille Fçranois, Richard O. Snyder, Magalie Penaud-Budloo, Véronique Blouin, Susan M. D'Costa

المساهمون: Center of Excellence for Regenerative Health Biotechnology [Florida, USA], University of Florida [Gainesville] (UF), Laboratoire de Thérapie Génique Translationnelle des Maladies Génétiques (Inserm UMR 1089), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM), Généthon, Department of Molecular Genetics and Microbiology [Gainesville, FL, USA] (Center for NeuroGenetics ), This work was performed under a Cooperative Agreement between CHU-Nantes, INSERM, AFM, and the University of Florida Center of Excellence for Regenerative Health Biotechnology., JAULIN, Nicolas, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)

المصدر: Molecular Therapy-Methods and Clinical Development
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2016, 5, pp.16019. ⟨10.1038/mtm.2016.19⟩
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Molecular Therapy. Methods & Clinical Development

مصطلحات موضوعية: 0301 basic medicine, Focus (geometry), lcsh:QH426-470, viruses, [SDV]Life Sciences [q-bio], Computational biology, Biology, Genome, Article, law.invention, 03 medical and health sciences, Plasmid, law, Genetics, Vector (molecular biology), lcsh:QH573-671, Molecular Biology, Reference standards, lcsh:Cytology, [SDV] Life Sciences [q-bio], Titer, lcsh:Genetics, 030104 developmental biology, Real-time polymerase chain reaction, Recombinant DNA, Molecular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9633be604bd5efac050fe3d1b1d1284b
https://www.hal.inserm.fr/inserm-01799010/document

المؤلفون: Manfred Schmidt, Richard O. Snyder, Christof von Kalle, Philippe Moullier, Caroline Le Guiner, Christine Kaeppel, Uwe Appelt, Ali Nowrouzi, Magalie Penaud-Budloo

المصدر: Molecular Therapy. 20:1177-1186

مصطلحات موضوعية: Primates, Virus Integration, viruses, Genetic enhancement, Genetic Vectors, Gene Dosage, Biology, Genome, Deep sequencing, Cell Line, law.invention, Proviruses, law, In vivo, Chlorocebus aethiops, Drug Discovery, Genetics, medicine, Animals, Humans, Vector (molecular biology), Muscle, Skeletal, Molecular Biology, Recombination, Genetic, Pharmacology, Breakpoint, Gene Transfer Techniques, Skeletal muscle, Dependovirus, Virology, medicine.anatomical_structure, Liver, COS Cells, Recombinant DNA, Molecular Medicine, Original Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfe1a5593075e3661cc4861c32fc568
https://doi.org/10.1038/mt.2012.47

المؤلفون: M Penaud-Budloo, C. Le Guiner, Philippe Moullier, Weiyi Ni, Richard O. Snyder, Gwladys Gernoux

المساهمون: Immunologie moléculaire et biothérapies innovantes (IMBI), Généthon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université d'Évry-Val-d'Essonne (UEVE)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Vecteurs viraux et transfert de gènes in vivo, Université de Nantes (UN)-IFR26-Institut National de la Santé et de la Recherche Médicale (INSERM), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université d'Évry-Val-d'Essonne (UEVE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Généthon

المصدر: Gene Ther
Gene Ther, 2011, 18 (7), pp.709-18. ⟨10.1038/gt.2011.19⟩

مصطلحات موضوعية: Leukocytes/chemistry, Time Factors, [SDV]Life Sciences [q-bio], Genetic enhancement, Pharmacokinetics, Polymerase Chain Reaction, 01 natural sciences, law.invention, Plasmids/*blood, Genetic Vectors, Plasmid, law, Leukocytes, Transgenes, Vector (molecular biology), Polymerase chain reaction, Doping in Sports, Intramuscular, 0303 health sciences, Gene Transfer Techniques, Viral/*blood, Dependovirus, Recombinant DNA, Molecular Medicine, Erythropoietin/*blood/*genetics, Plasmids, DNA/blood, Gene delivery, Biology, Injections, Intramuscular, Injections, Viral vector, 03 medical and health sciences, Computer Systems, Genetics, Animals, Dependovirus/*genetics, Erythropoietin, Molecular Biology, 030304 developmental biology, 010401 analytical chemistry, DNA, DNA extraction, Virology, Molecular biology, 0104 chemical sciences, Macaca fascicularis, DNA, Viral

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6aba3663dce98ff793c69f8ce83bf0
https://doi.org/10.1038/gt.2011.19

المؤلفون: Jeremy Plante, Richard O. Snyder, Jarrod Dean, Ryuichi Aikawa, Gordon S. Huggins

المصدر: Human Gene Therapy. 20:1005-1012

مصطلحات موضوعية: Chromatin Immunoprecipitation, Small interfering RNA, viruses, Genetic Vectors, Immunoblotting, Response element, Mice, Transgenic, CREB, Recombinant virus, medicine.disease_cause, Mice, Transduction (genetics), Transduction, Genetic, Genetics, medicine, Cyclic AMP Response Element-Binding Protein, Animals, Humans, Myocytes, Cardiac, Phosphorylation, RNA, Small Interfering, Molecular Biology, Transcription factor, Adeno-associated virus, Recombination, Genetic, biology, Isoproterenol, Dependovirus, Molecular biology, Rats, biology.protein, Molecular Medicine, Brief Reports

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9335fcb71cb946bdd96a80b9768e29
https://doi.org/10.1089/hum.2009.054

المؤلفون: Joyce D. Francis, Terence R. Flotte, Sergei Zolotukhin, Matt Petersen, Deena Sanders, Mark Potter, Richard O. Snyder, Irina Korytov, Glenn Phillipsberg, Nicholas Muzyczka, Jason Fife, Tina Phillipsberg

المصدر: BioProcessing Journal. 7:8-14

مصطلحات موضوعية: Serotype, law, Recombinant DNA, medicine, General Earth and Planetary Sciences, Vector (molecular biology), Biology, medicine.disease_cause, Reference standards, Virology, Adeno-associated virus, General Environmental Science, law.invention

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6ac62210e841408d7a7774fbbb8ffb4
https://doi.org/10.12665/j72.snyder