المؤلفون: Deborah L. Smith, Lee E. Schechter, Michael Z. Kagan, Nicole T. Hatzenbuhler, Amedeo Arturo Failli, Deborah Ann Evrard, Zhang Minsheng, Jeannette Golembieski, Richard Eric Mewshaw, Margaret Lai, Steven Edward Lenicek, Michael Chlenov, Jean Sze, Terrance H. Andree, Dahui Zhou, Annmarie L. Saab, Geoffrey Hornby, Reinhardt Bernhard Baudy, Boyd L. Harrison, Uresh Shantilal Shah, Kelly Sullivan

المصدر: Journal of Medicinal Chemistry. 51:6980-7004

مصطلحات موضوعية: Stereochemistry, Serotonin 5-HT1 Receptor Antagonists, Cell Line, Reuptake, Structure-Activity Relationship, Cricetinae, Drug Discovery, Animals, Humans, Moiety, Structure–activity relationship, Benzopyrans, heterocyclic compounds, Serotonin transporter, Serotonin Plasma Membrane Transport Proteins, Indole test, Molecular Structure, biology, Chemistry, Transporter, Antidepressive Agents, Rats, Cross-Linking Reagents, Receptor, Serotonin, 5-HT1A, biology.protein, Molecular Medicine, 5-HT1A receptor, Antagonism, Selective Serotonin Reuptake Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0888e59808afb3d9088f68290cf3d60e
https://doi.org/10.1021/jm8007097

المؤلفون: Eric S. Manas, Alison N. Campbell, Heather A. Harris, Rayomand J. Unwalla, An T. Vu, Richard Eric Mewshaw

المصدر: Bioorganic & Medicinal Chemistry Letters. 17:4053-4056

مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Ligand, Organic Chemistry, Clinical Biochemistry, Quinoline, Pharmaceutical Science, Estrogen receptor, Ligands, Biochemistry, Chemical synthesis, chemistry.chemical_compound, chemistry, Drug Discovery, Quinolines, Estrogen Receptor beta, Molecular Medicine, Selectivity, Molecular Biology, Estrogen receptor beta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b723646406c8931fa9820fe805cd74
https://doi.org/10.1016/j.bmcl.2007.04.068

المؤلفون: John W. Ullrich, Robert R. Singhaus, Rayomand J. Unwalla, Richard Eric Mewshaw, Heather A. Harris

المصدر: Bioorganic & Medicinal Chemistry Letters. 17:118-122

مصطلحات موضوعية: Indoles, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Estrogen receptor, Phthalimides, Crystallography, X-Ray, Ligands, Biochemistry, chemistry.chemical_compound, Estrogen-related receptor alpha, chemistry, Drug Discovery, Enzyme-linked receptor, Functional selectivity, Estrogen Receptor beta, Humans, Molecular Medicine, Estrogen-related receptor gamma, Isoindole, Molecular Biology, Estrogen receptor alpha, Estrogen receptor beta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3296fcf2b87a7a1605a5341c9c456a00
https://doi.org/10.1016/j.bmcl.2006.09.088

المؤلفون: Geoffrey Hornby, Boyd L. Harrison, Deborah L. Smith, Terrance H. Andree, Nicole T. Hatzenbuhler, Kelly Sullivan, Qian Lin, Dahui Zhou, Jennifer Ann Inghrim, Deborah Ann Evrard, Lee E. Schechter, James F. Mattes, Chad E. Beyer, Donna M. Huryn, Richard Eric Mewshaw, Christina M. Kraml

المصدر: Journal of Medicinal Chemistry. 49:4785-4789

مصطلحات موضوعية: Serotonin, Indoles, Stereochemistry, Microdialysis, CHO Cells, Serotonin 5-HT1 Receptor Antagonists, Radioligand Assay, Structure-Activity Relationship, Cricetulus, Neurochemical, Cricetinae, Drug Discovery, Animals, Humans, Structure–activity relationship, Benzopyrans, Chromans, Serotonin Uptake Inhibitors, Serotonin transporter, Serotonin Plasma Membrane Transport Proteins, biology, Chemistry, Stereoisomerism, Transporter, Biological activity, Serotonin 5-HT1 Receptor Agonists, Antidepressive Agents, Frontal Lobe, Rats, Biochemistry, biology.protein, Molecular Medicine, 5-HT1A receptor, Selective Serotonin Reuptake Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adec0af8aa36006968e26b141351e7c3
https://doi.org/10.1021/jm060218h

المؤلفون: Geoffrey Hornby, Boyd L. Harrison, Lee E. Schechter, Richard Eric Mewshaw, Deborah L. Smith, Terrance H. Andree, Uresh Shantilal Shah, Rosemary Scerni, Kelly Sullivan, Dahui Zhou

المصدر: Bioorganic & Medicinal Chemistry Letters. 16:1338-1341

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Substrate Specificity, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Humans, Structure–activity relationship, Neurotransmitter, Receptor, Molecular Biology, 5-HT receptor, Serotonin transporter, Serotonin Plasma Membrane Transport Proteins, Molecular Structure, biology, Organic Chemistry, Ligand (biochemistry), Antidepressive Agents, Benzoxazines, Rats, chemistry, Receptor, Serotonin, 5-HT1A, biology.protein, Molecular Medicine, 5-HT1A receptor, Serotonin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2071b00da03222195a222a5eaf5ea7d2
https://doi.org/10.1016/j.bmcl.2005.11.054

المؤلفون: An T. Vu, Stephen Todd Cohn, Heather A. Harris, Richard Eric Mewshaw, Eric S. Manas

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:4520-4525

مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Cell, Pharmaceutical Science, Estrogen receptor, Biochemistry, Partial agonist, Chemical synthesis, In vitro, Radioligand Assay, Structure-Activity Relationship, medicine.anatomical_structure, In vivo, Drug Discovery, Benzoquinones, medicine, Estrogen Receptor beta, Molecular Medicine, Binding site, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3e1d5aafd07bcc810cf5fea0af56b7
https://doi.org/10.1016/j.bmcl.2005.07.008

المؤلفون: Richard Eric Mewshaw, James C. Keith, Eric S. Manas, Cuijian Yang, Ruth A. Henderson, Heather A. Harris, Richard James Edsall, Zhang B. Xu

المصدر: Journal of Medicinal Chemistry. 48:3953-3979

مصطلحات موضوعية: Male, Models, Molecular, Transcription, Genetic, Stereochemistry, Molecular Conformation, Genistein, Naphthols, Naphthalenes, Crystallography, X-Ray, Ligands, Chemical synthesis, Animals, Genetically Modified, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, Animals, Estrogen Receptor beta, Humans, Structure–activity relationship, Moiety, Molecule, Binding site, Binding Sites, Molecular Structure, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Molecular Mimicry, Uterus, Organ Size, Inflammatory Bowel Diseases, Arthritis, Experimental, Rats, Rats, Inbred Lew, Docking (molecular), Molecular Medicine, Female, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c112a734513b436d503228a610bde1e3
https://doi.org/10.1021/jm058173s

المؤلفون: Geoffrey Hornby, Lee E. Schechter, Dahui Zhou, Deborah F. Smith, Taylor Spangler, Rosemary Scerni, Terrance H. Andree, Xiaojie Shi, Richard Eric Mewshaw, Ping Zhou

المصدر: Journal of Medicinal Chemistry. 47:3823-3842

مصطلحات موضوعية: Serotonin, Indoles, Intrinsic activity, Stereochemistry, Nerve Tissue Proteins, In Vitro Techniques, Cell Line, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Cricetinae, Receptors, Adrenergic, alpha-1, Drug Discovery, Animals, Humans, Moiety, Amines, Serotonin transporter, Cerebral Cortex, Serotonin Plasma Membrane Transport Proteins, Indole test, Membrane Glycoproteins, biology, Chemistry, Aryl, Membrane Transport Proteins, Transporter, Affinities, Antidepressive Agents, Rats, Receptor, Serotonin, 5-HT1A, biology.protein, Molecular Medicine, Serotonin Antagonists, Carrier Proteins, Reuptake inhibitor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dddb8db5e5221e60731dec1c296b815
https://doi.org/10.1021/jm0304010

المؤلفون: Richard Eric Mewshaw, Eric S. Manas, Richard James Edsall, Heather A. Harris

المصدر: Bioorganic & Medicinal Chemistry. 11:3457-3474

مصطلحات موضوعية: Models, Molecular, Molecular model, Protein Conformation, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Hydroxylation, Ligands, Biochemistry, Chemical synthesis, Substrate Specificity, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Estrogen Receptor beta, Binding site, Molecular Biology, Biphenyl, Molecular Structure, Chemistry, Ligand, Biphenyl Compounds, Organic Chemistry, Genistein, Receptors, Estrogen, Benzene derivatives, Molecular Medicine, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fd5c646d212e0000f9893edb064aac
https://doi.org/10.1016/s0968-0896(03)00303-1

المؤلفون: Richard Eric Mewshaw, Rulin Zhao, Terrance H. Andree, Hossein Mazandarani, Joseph Coupet, Xiaojie Shi, Julie A. Brennan, Karen L. Marquis

المصدر: Bioorganic & Medicinal Chemistry Letters. 12:271-274

مصطلحات موضوعية: Receptors, Dopamine D2, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Dopaminergic, Pharmaceutical Science, Templates, Genetic, Biochemistry, Chemical synthesis, Models, Structural, Structure-Activity Relationship, chemistry.chemical_compound, Dopamine Agonists, Drug Discovery, Molecular Medicine, Benzopyrans, Enantiomer, Molecular Biology, Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca858bb8d8f997289c34724edf5853c5
https://doi.org/10.1016/s0960-894x(01)00778-8

المؤلفون: Taylor Spangler, Deborah Ann Evrard, Lee E. Schechter, Rosemary Scerni, Deborah L. Smith, Kristin Lynne Meagher, Xiaojie Shi, Richard Eric Mewshaw, Ping Zhou, Terrance H. Andree, Susan Abulhawa

المصدر: Bioorganic & Medicinal Chemistry Letters. 11:1885-1888

مصطلحات موضوعية: Indoles, Clinical Biochemistry, Pharmaceutical Science, Nerve Tissue Proteins, CHO Cells, Pharmacology, Biochemistry, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Cricetinae, Drug Discovery, Animals, Humans, Structure–activity relationship, Neurotransmitter, Molecular Biology, Serotonin Plasma Membrane Transport Proteins, Cyclohexylamines, Membrane Glycoproteins, Chemistry, Organic Chemistry, Membrane Transport Proteins, Transporter, Receptors, Adrenergic, alpha, Serotonin reuptake, Serotonin metabolism, Antidepressive Agents, Rats, Receptors, Serotonin, Molecular Medicine, Serotonin, Carrier Proteins, Reuptake inhibitor, Receptors, Serotonin, 5-HT1, Selective Serotonin Reuptake Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef7f4d20ff06228cf6a3df4940e43a5
https://doi.org/10.1016/s0960-894x(01)00334-1

المؤلفون: Karen L. Marquis, Terrance H. Andree, Georgia B. McGaughey, Antoine Verwijs, James Albert Nelson, Joseph Coupet, Julie A. Brennan, Richard Eric Mewshaw, Xiaojie Shi, Hossein Mazandarani

المصدر: Bioorganic & Medicinal Chemistry Letters. 8:2675-2680

مصطلحات موضوعية: Agonist, Indoles, Molecular model, medicine.drug_class, Stereochemistry, Dopamine Agents, Clinical Biochemistry, Pharmaceutical Science, Phenylpiperazine, Biochemistry, Chemical synthesis, Piperazines, Structure-Activity Relationship, chemistry.chemical_compound, Dopamine receptor D2, Drug Discovery, medicine, Animals, Molecular Biology, Psychotropic Drugs, Bicyclic molecule, Receptors, Dopamine D2, Chemistry, Organic Chemistry, Dopaminergic, Receptors, Dopamine D3, Templates, Genetic, Ligand (biochemistry), Corpus Striatum, Rats, Kinetics, Dopamine Agonists, Molecular Medicine, Benzimidazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b420f2b135ef4e56d46372fa4d88b4
https://doi.org/10.1016/s0960-894x(98)00474-0

المؤلفون: Michael Byron Webb, Taylor Spangler, Magid Abou-Gharbia, Karen L. Marquis, Hossein Mazandarani, Georgia B. McGaughey, Julie A. Brennan, Theodore Wasik, Joseph Coupet, Rosemary Scerni, Terrance H. Andree, Gary Paul Stack, Richard Eric Mewshaw, Xiaojie Shi

المصدر: Tetrahedron. 54:7081-7108

مصطلحات موضوعية: Agonist, Indole test, Scaffold, Intrinsic activity, medicine.drug_class, Chemistry, Stereochemistry, Organic Chemistry, Dopaminergic, Rational design, Biochemistry, Combinatorial chemistry, Drug Discovery, medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::52739f381a6fde91b9f3f68e9e38eff1
https://doi.org/10.1016/s0040-4020(98)00349-4

المؤلفون: J. W. Ferkany, L. S. Silverman, Bailey Ma, Carol Tiffany, M E Abreu, Carl Kaiser, Karbon Ew, Richard Eric Mewshaw, Mathew Rm

المصدر: Journal of Medicinal Chemistry. 36:3073-3076

مصطلحات موضوعية: Indole test, chemistry.chemical_classification, Indoles, Bicyclic molecule, Receptors, Dopamine D2, Stereochemistry, Absolute configuration, Benzisoxazole, Stereoisomerism, Crystallography, X-Ray, chemistry.chemical_compound, Polycyclic compound, chemistry, Drug Design, Receptors, Serotonin, Drug Discovery, Molecular Medicine, Moiety, Enantiomer, Chromatography, High Pressure Liquid, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5ee9589e41e0558cbdd8a60233291a
https://doi.org/10.1021/jm00073a005

المؤلفون: Mathew Rm, J. W. Ferkany, Karbon Ew, Richard Eric Mewshaw, Bailey Ma, Carol Tiffany, Carl Kaiser, M E Abreu, L. S. Silverman

المصدر: ChemInform. 26

مصطلحات موضوعية: Indole test, chemistry.chemical_compound, chemistry, Stereochemistry, Benzisoxazole, Enantioselective synthesis, Absolute configuration, Moiety, General Medicine, Enantiomer, Receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0a7824f2d4c33985e3b062816a597446
https://doi.org/10.1002/chin.199503165

المؤلفون: Terrance H. Andree, Richard Eric Mewshaw, Xiaojie Shi, H. Mazandarani, A. Verwijs, Karen L. Marquis, Georgia B. McGaughey, Julie A. Brennan, James Albert Nelson, Joseph Coupet

المصدر: ChemInform. 30

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Dopaminergic, Phenylpiperazine, General Medicine, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9db81de2b830f6685171e8090f5d5285
https://doi.org/10.1002/chin.199908168

المؤلفون: Uresh Shantilal Shah, James Albert Nelson, Hossein Mazandarani, Karen L. Marquis, Joseph Coupet, Richard Eric Mewshaw, Xiaojie Shi, Julie A. Brennan, Terrance H. Andree

المصدر: ChemInform. 30

مصطلحات موضوعية: Exploit, Chemistry, Dopaminergic, General Medicine, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6110e0b7d4b9a92c6c6a9715fc5d74a9
https://doi.org/10.1002/chin.199949117

المؤلفون: Terrance H. Andree, Rosemary Scerni, Kristin Lynne Meagher, Deborah L. Smith, Dahui Zhou, Richard Eric Mewshaw, Ping Zhou, Lee E. Schechter, Xiaojie Shi

المصدر: ChemInform. 33

مصطلحات موضوعية: Indole test, Chemistry, Antagonist, Transporter, General Medicine, Serotonin reuptake, Pharmacology, Reuptake

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2eb30179ec1f254faef335c53d968185
https://doi.org/10.1002/chin.200224152

المؤلفون: Geoffrey Hornby, Kristin Lynne Meagher, Boyd L. Harrison, Terrance H. Andree, Michael A. Webb, Deborah Ann Evrard, Deborah L. Smith, Donna M. Huryn, Jeannette Golembieski, Richard Eric Mewshaw, Ping Zhou, Dahui Zhou, Lee E. Schechter

المصدر: Bioorganicmedicinal chemistry. 16(14)

مصطلحات موضوعية: Indoles, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Serotonin 5-HT1 Receptor Antagonists, Biochemistry, Piperazines, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Serotonin transporter, 5-HT receptor, Indole test, Serotonin Plasma Membrane Transport Proteins, Cyclohexylamines, biology, Chemistry, Organic Chemistry, Transporter, Quinoline analog, Receptor antagonist, Antidepressive Agents, Receptor, Serotonin, 5-HT1A, biology.protein, Molecular Medicine, 5-HT1A receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827e3bb0ccf60af6fe428238a6482e13
https://pubmed.ncbi.nlm.nih.gov/18571421

المؤلفون: Richard Eric Mewshaw, Stephen Todd Cohn, Zhang B. Xu, S. Marc Bowen, Eric S. Manas, Heather A. Harris

المصدر: Bioorganicmedicinal chemistry letters. 17(4)

مصطلحات موضوعية: Models, Molecular, Selective Estrogen Receptor Modulators, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Ligands, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Oximes, Moiety, Estrogen Receptor beta, Humans, Molecular Biology, Aldehydes, Bicyclic molecule, Chemistry, Ligand, Aryl, Organic Chemistry, Oxime, Docking (molecular), Molecular Medicine, Indicators and Reagents, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ac337cb30c3716a6c768c1b6353510
https://pubmed.ncbi.nlm.nih.gov/17188490