المؤلفون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

المصدر: Molecular Cancer, Vol 22, Iss 1, Pp 1-37 (2023)

مصطلحات موضوعية: PI3K/AKT/mTORC pathway, Pan PI3K inhibitors, Isoform-specific PI3K inhibitors, Dual PI3K/mTOR inhibitors, AKT inhibitors, Allosteric mTOR inhibitors, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1476-4598

URL الوصول: https://doaj.org/article/9b643e4724194798a585634205af8fef

المؤلفون: R. C. Coombes, Sacha Howell, Simon R. Lord, Laura Kenny, Janine Mansi, Zahi Mitri, Carlo Palmieri, Linnea I. Chap, Paul Richards, William Gradishar, Sagar Sardesai, Jason Melear, Joyce O’Shaughnessy, Patrick Ward, Pavani Chalasani, Tobias Arkenau, Richard D. Baird, Rinath Jeselsohn, Simak Ali, Glen Clack, Ashwani Bahl, Stuart McIntosh, Matthew G. Krebs

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/b14be29b81754bafad04d4aa37714251

المؤلفون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, Plant Biology, Computational Biology, PI3K/AKT/mTORC pathway, Pan PI3K inhibitors, Isoform-specific PI3K inhibitors, Dual PI3K/mTOR inhibitors, AKT inhibitors, Allosteric mTOR inhibitors, ATP-competitive mTOR inhibitors, Bi-steric mTOR inhibitors, PDK1 inhibitors

Relation: https://figshare.com/articles/presentation/Additional_file_1_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597442

الاتاحة: https://doi.org/10.6084/m9.figshare.24597442.v1
https://figshare.com/articles/presentation/Additional_file_1_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597442

المؤلفون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, Plant Biology, Computational Biology, PI3K/AKT/mTORC pathway, Pan PI3K inhibitors, Isoform-specific PI3K inhibitors, Dual PI3K/mTOR inhibitors, AKT inhibitors, Allosteric mTOR inhibitors, ATP-competitive mTOR inhibitors, Bi-steric mTOR inhibitors, PDK1 inhibitors

Relation: https://figshare.com/articles/journal_contribution/Additional_file_7_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597460

الاتاحة: https://doi.org/10.6084/m9.figshare.24597460.v1
https://figshare.com/articles/journal_contribution/Additional_file_7_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597460

المؤلفون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, Plant Biology, Computational Biology, PI3K/AKT/mTORC pathway, Pan PI3K inhibitors, Isoform-specific PI3K inhibitors, Dual PI3K/mTOR inhibitors, AKT inhibitors, Allosteric mTOR inhibitors, ATP-competitive mTOR inhibitors, Bi-steric mTOR inhibitors, PDK1 inhibitors

Relation: https://figshare.com/articles/journal_contribution/Additional_file_5_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597454

الاتاحة: https://doi.org/10.6084/m9.figshare.24597454.v1
https://figshare.com/articles/journal_contribution/Additional_file_5_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597454

المؤلفون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, Plant Biology, Computational Biology, PI3K/AKT/mTORC pathway, Pan PI3K inhibitors, Isoform-specific PI3K inhibitors, Dual PI3K/mTOR inhibitors, AKT inhibitors, Allosteric mTOR inhibitors, ATP-competitive mTOR inhibitors, Bi-steric mTOR inhibitors, PDK1 inhibitors

Relation: https://figshare.com/articles/journal_contribution/Additional_file_3_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597448

الاتاحة: https://doi.org/10.6084/m9.figshare.24597448.v1
https://figshare.com/articles/journal_contribution/Additional_file_3_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597448

المؤلفون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, Plant Biology, Computational Biology, PI3K/AKT/mTORC pathway, Pan PI3K inhibitors, Isoform-specific PI3K inhibitors, Dual PI3K/mTOR inhibitors, AKT inhibitors, Allosteric mTOR inhibitors, ATP-competitive mTOR inhibitors, Bi-steric mTOR inhibitors, PDK1 inhibitors

Relation: https://figshare.com/articles/journal_contribution/Additional_file_4_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597451

الاتاحة: https://doi.org/10.6084/m9.figshare.24597451.v1
https://figshare.com/articles/journal_contribution/Additional_file_4_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597451

المؤلفون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, Plant Biology, Computational Biology, PI3K/AKT/mTORC pathway, Pan PI3K inhibitors, Isoform-specific PI3K inhibitors, Dual PI3K/mTOR inhibitors, AKT inhibitors, Allosteric mTOR inhibitors, ATP-competitive mTOR inhibitors, Bi-steric mTOR inhibitors, PDK1 inhibitors

Relation: https://figshare.com/articles/journal_contribution/Additional_file_2_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597445

الاتاحة: https://doi.org/10.6084/m9.figshare.24597445.v1
https://figshare.com/articles/journal_contribution/Additional_file_2_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597445

المؤلفون: Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, Plant Biology, Computational Biology, PI3K/AKT/mTORC pathway, Pan PI3K inhibitors, Isoform-specific PI3K inhibitors, Dual PI3K/mTOR inhibitors, AKT inhibitors, Allosteric mTOR inhibitors, ATP-competitive mTOR inhibitors, Bi-steric mTOR inhibitors, PDK1 inhibitors

Relation: https://figshare.com/articles/journal_contribution/Additional_file_6_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597457

الاتاحة: https://doi.org/10.6084/m9.figshare.24597457.v1
https://figshare.com/articles/journal_contribution/Additional_file_6_of_PI3K_AKT_mTOR_signaling_transduction_pathway_and_targeted_therapies_in_cancer/24597457

المؤلفون: Alistair Ring, Lucy S. Kilburn, Alex Pearson, Laura Moretti, Angelica Afshari-Mehr, Andrew M. Wardley, Bora Gurel, Iain R. Macpherson, Ruth Riisnaes, Richard D. Baird, Sue Martin, Rebecca Roylance, Hannah Johnson, Ana Ferreira, Matthew C. Winter, Kathryn Dunne, Ellen Copson, Tamas Hickish, Russell Burcombe, Kat Randle, Violeta Serra, Alba Llop-Guevara, Judith M. Bliss, Nicolas C. Turner

مصطلحات موضوعية: Cancer, Cancer Detection and Diagnosis, Clinical Research and Trials, Biomarkers, Circulating tumor cells/DNA/exosomes, Breast Cancer, Clinical Trial Results, Phase II clinical trials

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Table_S2_from_Olaparib_and_Ceralasertib_AZD6738_in_Patients_with_Triple-Negative_Advanced_Breast_Cancer_Results_from_Cohort_E_of_the_plasmaMATCH_Trial_CRUK_15_010_/24710741

الاتاحة: https://doi.org/10.1158/1078-0432.24710741.v1
https://figshare.com/articles/journal_contribution/Supplementary_Table_S2_from_Olaparib_and_Ceralasertib_AZD6738_in_Patients_with_Triple-Negative_Advanced_Breast_Cancer_Results_from_Cohort_E_of_the_plasmaMATCH_Trial_CRUK_15_010_/24710741

المؤلفون: Alistair Ring, Lucy S. Kilburn, Alex Pearson, Laura Moretti, Angelica Afshari-Mehr, Andrew M. Wardley, Bora Gurel, Iain R. Macpherson, Ruth Riisnaes, Richard D. Baird, Sue Martin, Rebecca Roylance, Hannah Johnson, Ana Ferreira, Matthew C. Winter, Kathryn Dunne, Ellen Copson, Tamas Hickish, Russell Burcombe, Kat Randle, Violeta Serra, Alba Llop-Guevara, Judith M. Bliss, Nicolas C. Turner

مصطلحات موضوعية: Cancer, Cancer Detection and Diagnosis, Clinical Research and Trials, Biomarkers, Circulating tumor cells/DNA/exosomes, Breast Cancer, Clinical Trial Results, Phase II clinical trials

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Figure_S2_from_Olaparib_and_Ceralasertib_AZD6738_in_Patients_with_Triple-Negative_Advanced_Breast_Cancer_Results_from_Cohort_E_of_the_plasmaMATCH_Trial_CRUK_15_010_/24710750

الاتاحة: https://doi.org/10.1158/1078-0432.24710750.v1
https://figshare.com/articles/journal_contribution/Supplementary_Figure_S2_from_Olaparib_and_Ceralasertib_AZD6738_in_Patients_with_Triple-Negative_Advanced_Breast_Cancer_Results_from_Cohort_E_of_the_plasmaMATCH_Trial_CRUK_15_010_/24710750

المؤلفون: R. C. Coombes, Sacha Howell, Simon R. Lord, Laura Kenny, Janine Mansi, Zahi Mitri, Carlo Palmieri, Linnea I. Chap, Paul Richards, William Gradishar, Sagar Sardesai, Jason Melear, Joyce O’Shaughnessy, Patrick Ward, Pavani Chalasani, Tobias Arkenau, Richard D. Baird, Rinath Jeselsohn, Simak Ali, Glen Clack, Ashwani Bahl, Stuart McIntosh, Matthew G. Krebs

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)

مصطلحات موضوعية: Science

Relation: https://doi.org/10.1038/s41467-023-40561-x; https://doaj.org/toc/2041-1723; https://doaj.org/article/4ff05e79a58f49b980db63215fe0a4b3

الاتاحة: https://doi.org/10.1038/s41467-023-40561-x
https://doaj.org/article/4ff05e79a58f49b980db63215fe0a4b3

المؤلفون: Belinda Kingston, Rosalind J. Cutts, Hannah Bye, Matthew Beaney, Giselle Walsh-Crestani, Sarah Hrebien, Claire Swift, Lucy S. Kilburn, Sarah Kernaghan, Laura Moretti, Katie Wilkinson, Andrew M. Wardley, Iain R. Macpherson, Richard D. Baird, Rebecca Roylance, Jorge S. Reis-Filho, Michael Hubank, Iris Faull, Kimberly C. Banks, Richard B. Lanman, Isaac Garcia-Murillas, Judith M. Bliss, Alistair Ring, Nicholas C. Turner

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/5f176e5d5bcb4792adb4ec1effb35966

المؤلفون: Iain R. Macpherson, Pavlina Spiliopoulou, Saeed Rafii, Matilde Saggese, Richard D. Baird, Javier Garcia-Corbacho, Antoine Italiano, Jacques Bonneterre, Mario Campone, Nicola Cresti, John Posner, Yousuke Takeda, Akinori Arimura, James Spicer

المصدر: Breast Cancer Research, Vol 22, Iss 1, Pp 1-9 (2019)

مصطلحات موضوعية: Epertinib, EGFR, HER2, HER2-positive breast cancer, Trastuzumab, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1465-542X

URL الوصول: https://doaj.org/article/1caffbf612894f738efaee3a4d3d13dc

المؤلفون: Belinda Kingston, Rosalind J. Cutts, Hannah Bye, Matthew Beaney, Giselle Walsh-Crestani, Sarah Hrebien, Claire Swift, Lucy S. Kilburn, Sarah Kernaghan, Laura Moretti, Katie Wilkinson, Andrew M. Wardley, Iain R. Macpherson, Richard D. Baird, Rebecca Roylance, Jorge S. Reis-Filho, Michael Hubank, Iris Faull, Kimberly C. Banks, Richard B. Lanman, Isaac Garcia-Murillas, Judith M. Bliss, Alistair Ring, Nicholas C. Turner

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)

مصطلحات موضوعية: Science

Relation: https://doi.org/10.1038/s41467-021-24791-5; https://doaj.org/toc/2041-1723; https://doaj.org/article/c4a8fb81f49749e99d11db28fb611c64

الاتاحة: https://doi.org/10.1038/s41467-021-24791-5
https://doaj.org/article/c4a8fb81f49749e99d11db28fb611c64

المؤلفون: Florence I. Raynaud, Johann S. de Bono, Paul Workman, Stan B. Kaye, Suzanne A. Eccles, Bart Vanhaesebroeck, Mika Derynck, Lori Friedman, Richard D. Baird, Alexis de Haven Brandon, Gary Box, Melanie Valenti, Alan T. Henley, Yasmin J. Asad, Joo Chew Ang, Rupinder Pandher, Joo Ern Ang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35242fa0e3a742cbb6b034b2187e5495
https://doi.org/10.1158/1535-7163.22503601

المؤلفون: Florence I. Raynaud, Johann S. de Bono, Paul Workman, Stan B. Kaye, Suzanne A. Eccles, Bart Vanhaesebroeck, Mika Derynck, Lori Friedman, Richard D. Baird, Alexis de Haven Brandon, Gary Box, Melanie Valenti, Alan T. Henley, Yasmin J. Asad, Joo Chew Ang, Rupinder Pandher, Joo Ern Ang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4f1e3fff57a56a184d3e834e92b978
https://doi.org/10.1158/1535-7163.22503598.v1

المؤلفون: Florence I. Raynaud, Johann S. de Bono, Paul Workman, Stan B. Kaye, Suzanne A. Eccles, Bart Vanhaesebroeck, Mika Derynck, Lori Friedman, Richard D. Baird, Alexis de Haven Brandon, Gary Box, Melanie Valenti, Alan T. Henley, Yasmin J. Asad, Joo Chew Ang, Rupinder Pandher, Joo Ern Ang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4068e9bc95db86ee6248750810664f56
https://doi.org/10.1158/1535-7163.22503595

المؤلفون: Florence I. Raynaud, Johann S. de Bono, Paul Workman, Stan B. Kaye, Suzanne A. Eccles, Bart Vanhaesebroeck, Mika Derynck, Lori Friedman, Richard D. Baird, Alexis de Haven Brandon, Gary Box, Melanie Valenti, Alan T. Henley, Yasmin J. Asad, Joo Chew Ang, Rupinder Pandher, Joo Ern Ang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146f091d32f617a6f33545ed2ab9f842
https://doi.org/10.1158/1535-7163.22503592.v1

المؤلفون: Florence I. Raynaud, Johann S. de Bono, Paul Workman, Stan B. Kaye, Suzanne A. Eccles, Bart Vanhaesebroeck, Mika Derynck, Lori Friedman, Richard D. Baird, Alexis de Haven Brandon, Gary Box, Melanie Valenti, Alan T. Henley, Yasmin J. Asad, Joo Chew Ang, Rupinder Pandher, Joo Ern Ang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783e2038908da754470e738776ff331e
https://doi.org/10.1158/1535-7163.22503604