المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Secondary_structure_topology_diagram_of_EphA2_LBD_gL_and_ephrin-A1_/16598096

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s003

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Binding_of_WT_gH_gL_and_EphA2_at_low_pH_and_in_inverted_system_/16598114

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s009

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Oligomeric_assemblies_formed_by_EphA2_ectodomains_/16598090

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s002

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Supporting_materials_and_methods_/16598141

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s018

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Illustration_of_the_BLI_setup_/16598111

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s008

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Alignment_of_gL_sequences_from_gammaherpesviruses_/16598120

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s011

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Analyses_of_gH_gL_and_ephrin-A1_interfaces_with_EphA2_LBD_/16598105

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s006

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Original_western_blot_image_/16598147

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s020

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Interfaces_between_gH_gL_and_EphA2_LBD_/16598135

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s016

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/FSI-FRET_data_proximity-corrected_FRET_efficiencies_donor_concentrations_and_acceptor_concentrations_/16598117

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s010

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Crystallographic_statistic_/16598132

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s015

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/EphA2_assemblies_and_contacts_observed_in_the_crystal_/16598123

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s012

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/Properties_of_the_dimerization_interface_DIN_in_EphA2_in_unliganded_form_and_bound_to_ligands_/16598138

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s017

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/journal_contribution/References_for_Supporting_information_figures_text_and_tables_/16598144

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s019

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/dataset/Excel_spreadsheet_containing_the_underlying_numerical_values_for_supporting_figures_and_panels_S4_S6_S9A_S9B_and_S10A_S10N_Figs_/16598129

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s014

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/dataset/Excel_spreadsheet_containing_the_underlying_numerical_values_for_the_main_text_figure_panels_Figs_2C_2D_4A_4D_5A_5D_6B_and_6D_/16598126

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.s013

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/figure/The_gH_gL-induced_EphA2_dimers_on_cells_engage_the_dimerization_interface_/16598162

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.g005

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/figure/Structural_mimicry_between_HHV-8_gH_gL_and_ephrin_ligands_/16598156

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.g003

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/figure/The_binding_interface_between_EphA2_LBD_and_HHV-8_gH_gL_/16598153

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.g002

المؤلفون: Taylor P. Light (3725941), Delphine Brun (11414366), Pablo Guardado-Calvo (2325709), Riccardo Pederzoli (11414369), Ahmed Haouz (5624486), Frank Neipel (554592), Félix A. Rey (3254583), Kalina Hristova (303684), Marija Backovic (3087789)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Biotechnology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, receptor &# 8217, ray structure analysis, provide novel insight, cell contraction assays, endosomal cellular membranes, cellular receptors hijacked, viral surface glycoproteins, 8 &# 8211, cellular ligands, using x, using fsi, therapeutic agents, terminal peptide, targeted mutagenesis, subnanomolar affinity, process mediated, pivotal role, opening avenues, oncogenic virus, mechanistic basis, gain access

Relation: https://figshare.com/articles/figure/Schematic_representation_of_HHV-8_gH_gL_and_EphA2_and_structure_of_the_gH_gL-EphA2_LBD_complex_/16598150

الاتاحة: https://doi.org/10.1371/journal.pbio.3001392.g001