المؤلفون: Jingwei Cheng, Donglim Esther Park, Christian Berrios, Elizabeth A White, Reety Arora, Rosa Yoon, Timothy Branigan, Tengfei Xiao, Thomas Westerling, Alexander Federation, Rhamy Zeid, Benjamin Strober, Selene K Swanson, Laurence Florens, James E Bradner, Myles Brown, Peter M Howley, Megha Padi, Michael P Washburn, James A DeCaprio

المصدر: PLoS Pathogens, Vol 13, Iss 10, p e1006668 (2017)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/09d9ce0281074c5285116f21831c3c3c

المؤلفون: Gesine K. Veits, Christina S. Henderson, Abigail Vogelaar, Scott J. Eron, Linda Lee, Ashley Hart, Richard W. Deibler, Joelle Baddour, W. Austin Elam, Roman V. Agafonov, Jessica Freda, Prasoon Chaturvedi, Brendon Ladd, Mark W. Carlson, Harit U. Vora, Thomas G. Scott, Trang Tieu, Arushi Jain, Chi-Li Chen, Emily S. Kibbler, Marius S. Pop, Minsheng He, Gunther Kern, Hannah J. Maple, Graham P. Marsh, Mark C. Norley, Catherine S. Oakes, James A. Henderson, Mathew E. Sowa, Andrew J. Phillips, David A. Proia, Eunice S. Park, Joe Sahil Patel, Stewart L. Fisher, Christopher G. Nasveschuk, Rhamy Zeid

المصدر: Current Research in Chemical Biology, Vol 1, Iss , Pp 100010- (2021)

مصطلحات موضوعية: Targeted protein degradation, aTAG, Target validation, Medicinal chemistry, Drug discovery, Biochemistry, QD415-436

Relation: http://www.sciencedirect.com/science/article/pii/S2666246921000100; https://doaj.org/toc/2666-2469; https://doaj.org/article/a1c74bbe925844a5ade33d5ac2fd74a4

الاتاحة: https://doi.org/10.1016/j.crchbi.2021.100010
https://doaj.org/article/a1c74bbe925844a5ade33d5ac2fd74a4

المؤلفون: Kimberly Stegmaier, James E. Bradner, William A. Weiss, Andrew L. Kung, Cyril H. Benes, Ultan McDermott, Matthew J. Garnett, Patricia Greninger, William Clay Gustafson, Rhamy Zeid, Erin A. Nekritz, Yvan H. Chanthery, Jun Qi, Christopher F. Bassil, Gabriela Alexe, Stacey M. Frumm, Alexandre Puissant

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682ea2c7e42559f3d316d32690345a6f
https://doi.org/10.1158/2159-8290.22530195

المؤلفون: Kimberly Stegmaier, James E. Bradner, William A. Weiss, Andrew L. Kung, Cyril H. Benes, Ultan McDermott, Matthew J. Garnett, Patricia Greninger, William Clay Gustafson, Rhamy Zeid, Erin A. Nekritz, Yvan H. Chanthery, Jun Qi, Christopher F. Bassil, Gabriela Alexe, Stacey M. Frumm, Alexandre Puissant

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e02cf876dc6f8e2b4937ebdbaa11b97
https://doi.org/10.1158/2159-8290.22530198.v1

المؤلفون: Yoon-Jae Cho, Rameen Beroukhim, James E. Bradner, Mark W. Kieran, Fredrik J. Swartling, William A. Weiss, Robert Wechsler-Reya, Kun-Wei Liu, Jun Qi, Samuel H. Cheshier, Siddhartha S. Mitra, Brenton R. Paolella, William J. Gibson, Nujsaubnusi Vue, Furong Yu, Sabran Masoud, Rhamy Zeid, Steven E. Schumacher, Sara Bolin, Yujie Tang, Sharareh Gholamin, Simone Schubert, Brian Nguyen, Guillaume Bergthold, Pratiti Bandopadhayay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27dd852222fc49c646a3b9e916833daa
https://doi.org/10.1158/1078-0432.c.6521883.v1

المؤلفون: Yoon-Jae Cho, Rameen Beroukhim, James E. Bradner, Mark W. Kieran, Fredrik J. Swartling, William A. Weiss, Robert Wechsler-Reya, Kun-Wei Liu, Jun Qi, Samuel H. Cheshier, Siddhartha S. Mitra, Brenton R. Paolella, William J. Gibson, Nujsaubnusi Vue, Furong Yu, Sabran Masoud, Rhamy Zeid, Steven E. Schumacher, Sara Bolin, Yujie Tang, Sharareh Gholamin, Simone Schubert, Brian Nguyen, Guillaume Bergthold, Pratiti Bandopadhayay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c28be7bf2edac35abba7faa9dddb9fe
https://doi.org/10.1158/1078-0432.22450230

المؤلفون: Yoon-Jae Cho, Rameen Beroukhim, James E. Bradner, Mark W. Kieran, Fredrik J. Swartling, William A. Weiss, Robert Wechsler-Reya, Kun-Wei Liu, Jun Qi, Samuel H. Cheshier, Siddhartha S. Mitra, Brenton R. Paolella, William J. Gibson, Nujsaubnusi Vue, Furong Yu, Sabran Masoud, Rhamy Zeid, Steven E. Schumacher, Sara Bolin, Yujie Tang, Sharareh Gholamin, Simone Schubert, Brian Nguyen, Guillaume Bergthold, Pratiti Bandopadhayay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69daa5f6bfce62d893f5fe33f240c6a5
https://doi.org/10.1158/1078-0432.22450233.v1

المؤلفون: Yoon-Jae Cho, Rameen Beroukhim, James E. Bradner, Mark W. Kieran, Fredrik J. Swartling, William A. Weiss, Robert Wechsler-Reya, Kun-Wei Liu, Jun Qi, Samuel H. Cheshier, Siddhartha S. Mitra, Brenton R. Paolella, William J. Gibson, Nujsaubnusi Vue, Furong Yu, Sabran Masoud, Rhamy Zeid, Steven E. Schumacher, Sara Bolin, Yujie Tang, Sharareh Gholamin, Simone Schubert, Brian Nguyen, Guillaume Bergthold, Pratiti Bandopadhayay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7cb1104e35b9e0c96d3a8414793743
https://doi.org/10.1158/1078-0432.22450224

المؤلفون: Yoon-Jae Cho, Rameen Beroukhim, James E. Bradner, Mark W. Kieran, Fredrik J. Swartling, William A. Weiss, Robert Wechsler-Reya, Kun-Wei Liu, Jun Qi, Samuel H. Cheshier, Siddhartha S. Mitra, Brenton R. Paolella, William J. Gibson, Nujsaubnusi Vue, Furong Yu, Sabran Masoud, Rhamy Zeid, Steven E. Schumacher, Sara Bolin, Yujie Tang, Sharareh Gholamin, Simone Schubert, Brian Nguyen, Guillaume Bergthold, Pratiti Bandopadhayay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d48a62ae4462bdbb031412e3f3e0f6
https://doi.org/10.1158/1078-0432.22450218.v1

المؤلفون: Yoon-Jae Cho, Rameen Beroukhim, James E. Bradner, Mark W. Kieran, Fredrik J. Swartling, William A. Weiss, Robert Wechsler-Reya, Kun-Wei Liu, Jun Qi, Samuel H. Cheshier, Siddhartha S. Mitra, Brenton R. Paolella, William J. Gibson, Nujsaubnusi Vue, Furong Yu, Sabran Masoud, Rhamy Zeid, Steven E. Schumacher, Sara Bolin, Yujie Tang, Sharareh Gholamin, Simone Schubert, Brian Nguyen, Guillaume Bergthold, Pratiti Bandopadhayay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bd97313673de5179c3ad7cd6434f6b
https://doi.org/10.1158/1078-0432.22450215.v1

المؤلفون: Yoon-Jae Cho, Rameen Beroukhim, James E. Bradner, Mark W. Kieran, Fredrik J. Swartling, William A. Weiss, Robert Wechsler-Reya, Kun-Wei Liu, Jun Qi, Samuel H. Cheshier, Siddhartha S. Mitra, Brenton R. Paolella, William J. Gibson, Nujsaubnusi Vue, Furong Yu, Sabran Masoud, Rhamy Zeid, Steven E. Schumacher, Sara Bolin, Yujie Tang, Sharareh Gholamin, Simone Schubert, Brian Nguyen, Guillaume Bergthold, Pratiti Bandopadhayay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663397e135c917156f1a075999f18438
https://doi.org/10.1158/1078-0432.22450221

المؤلفون: Yoon-Jae Cho, Rameen Beroukhim, James E. Bradner, Mark W. Kieran, Fredrik J. Swartling, William A. Weiss, Robert Wechsler-Reya, Kun-Wei Liu, Jun Qi, Samuel H. Cheshier, Siddhartha S. Mitra, Brenton R. Paolella, William J. Gibson, Nujsaubnusi Vue, Furong Yu, Sabran Masoud, Rhamy Zeid, Steven E. Schumacher, Sara Bolin, Yujie Tang, Sharareh Gholamin, Simone Schubert, Brian Nguyen, Guillaume Bergthold, Pratiti Bandopadhayay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab6de86130fd98eb2b68bc484ccb3e4
https://doi.org/10.1158/1078-0432.22450212.v1

المؤلفون: Yoon-Jae Cho, Rameen Beroukhim, James E. Bradner, Mark W. Kieran, Fredrik J. Swartling, William A. Weiss, Robert Wechsler-Reya, Kun-Wei Liu, Jun Qi, Samuel H. Cheshier, Siddhartha S. Mitra, Brenton R. Paolella, William J. Gibson, Nujsaubnusi Vue, Furong Yu, Sabran Masoud, Rhamy Zeid, Steven E. Schumacher, Sara Bolin, Yujie Tang, Sharareh Gholamin, Simone Schubert, Brian Nguyen, Guillaume Bergthold, Pratiti Bandopadhayay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cff4b894c6a3a67a5a9afa6c2db09ea
https://doi.org/10.1158/1078-0432.22450227

المؤلفون: Katrina L. Jackson, Roman V. Agafonov, Mark W. Carlson, Prasoon Chaturvedi, David Cocozziello, Kyle Cole, Richard Deibler, Scott J. Eron, Andrew Good, Ashley A. Hart, Minsheng He, Christina S. Henderson, Hongwei Huang, Marta Isasa, R. Jason Kirby, Linda Lee, Michelle Mahler, Moses Moustakim, Christopher G. Nasveschuk, Michael Palmer, Laura L. Poling, Roy M. Pollock, Matthew Schnaderbeck, Stan Spence, Gesine K. Veits, Jeremy L. Yap, Ning Yin, Rhamy Zeid, Adam S. Crystal, Andrew J. Phillips, Stewart L. Fisher

المصدر: Cancer Research. 82:ND09-ND09

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::96b44ef5d9fa5dc56a4a294008bf6985
https://doi.org/10.1158/1538-7445.am2022-nd09

المؤلفون: Joe Sahil Patel, Eunice S. Park, Chi-Li Chen, Andrew J. K. Phillips, Linda Lee, Thomas G. Scott, Christina S. Henderson, Ashley A. Hart, David A. Proia, James A. Henderson, W. Austin Elam, Catherine S. Oakes, Trang N. Tieu, Joelle Baddour, Mark C. Norley, Mathew E. Sowa, Jessica Freda, Marius S. Pop, Brendon Ladd, Minsheng He, Christopher G. Nasveschuk, Harit U. Vora, Gunther Kern, Gesine Kerstin Veits, Abigail Vogelaar, Stewart L. Fisher, Richard W. Deibler, Rhamy Zeid, Mark W. Carlson, Roman V. Agafonov, Arushi Jain, Graham P. Marsh, Prasoon Chaturvedi, Hannah J. Maple, Scott J. Eron, Emily S. Kibbler

المصدر: Current Research in Chemical Biology, Vol 1, Iss, Pp 100010-(2021)

مصطلحات موضوعية: Chemistry, Drug discovery, Chemical biology, Medicinal chemistry, Computational biology, QD415-436, Protein degradation, Biochemistry, Target validation, CAR PROTEIN, Pharmacology (medical), Target protein, Car t cells, Targeted protein degradation, aTAG

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fae8825e77dd3f8f25ec2a5b2702cc
http://www.sciencedirect.com/science/article/pii/S2666246921000100

المؤلفون: Mariateresa Fulciniti, Zoe Jacobson, Georg E. Winter, Michael A. Erb, Michael A. Lopez, Evon Poon, Donald R. Polaski, Thomas F. Westbrook, Jaime M. Reyes, James E. Bradner, Matthew A. Lawlor, Charles Y. Lin, Rachel A. Hirsch, Rhamy Zeid, Nikhil P. Munshi, Louis Chesler, Behnam Nabet, Kristen L. Karlin, Thomas G. Scott

المصدر: Nature Genetics. 50:515-523

مصطلحات موضوعية: 0301 basic medicine, Genes, myc, Biology, N-Myc Proto-Oncogene Protein, Article, Neuroblastoma, 03 medical and health sciences, Twist transcription factor, Transcription (biology), Cell Line, Tumor, Genetics, medicine, Humans, Promoter Regions, Genetic, Enhancer, neoplasms, Transcription factor, Binding Sites, Twist-Related Protein 1, Gene Amplification, Nuclear Proteins, Promoter, Oncogenes, medicine.disease, Chromatin, Cell biology, Kinetics, Enhancer Elements, Genetic, 030104 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fa9dc6c212cc89df74f448dcc03322
https://doi.org/10.1038/s41588-018-0044-9

المؤلفون: Dennis L. Buckley, Rhamy Zeid, Behnam Nabet, Neville E. Sanjana, Nana K. Offei-Addo, Huafeng Xie, Georg E. Winter, Feng Zhang, Justin M. Roberts, Bin E. Li, Amanda Souza, James E. Bradner, Michael A. Erb, Stuart H. Orkin, Joshiawa Paulk, Sirano Dhe-Paganon, Shiva Dastjerdi, Ophir Shalem, Thomas G. Scott, Hyuk-Soo Seo

المصدر: Nature

مصطلحات موضوعية: 0301 basic medicine, Transcription Elongation, Genetic, Transcription, Genetic, RNA polymerase II, Protein degradation, Article, Epigenesis, Genetic, Mice, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Transcription (biology), Cell Line, Tumor, hemic and lymphatic diseases, medicine, Animals, Humans, Cancer epigenetics, Gene, Cell Proliferation, Gene Editing, Regulation of gene expression, Genome, Leukemia, Multidisciplinary, biology, Histone-Lysine N-Methyltransferase, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, 3. Good health, Chromatin, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Leukemia, Myeloid, Acute, 030104 developmental biology, 030220 oncology & carcinogenesis, Proteolysis, Immunology, biology.protein, Cancer research, RNA Polymerase II, CRISPR-Cas Systems, Transcriptional Elongation Factors, Myeloid-Lymphoid Leukemia Protein, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ece45e147973aed662dc45fa329e35b
http://europepmc.org/articles/PMC5497220

المؤلفون: Paloma Cejas, Jayati Anand, Jason S. Carroll, James E. Bradner, Tom O. McDonald, Sudeepa Syamala, Xintao Qiu, Evangelia K. Papachristou, Katherine Murphy, Hua-Jun Wu, Isaac S. Harris, Alba Font-Tello, Joan S. Brugge, Kornelia Polyak, X. Shirley Liu, Klothilda Lim, Cigall Kadoch, Jaime M. Reyes, Tengfei Xiao, Quang-Dé Nguyen, Kai W. Wucherpfennig, Rhamy Zeid, Brittany C. Michel, Clive D'Santos, Myles Brown, Wei Li, Adrienne M. Luoma, Binbin Wang, Jennifer Y Ge, Kunihiko Hinohara, Jennifer E. Endress, Jacob D. Jaffe, Chandra Sekhar Reddy Chilamakuri, Shaokun Shu, Jun Qi, Rebecca Modiste, Bojana Jovanovic, Franziska Michor, Henry W. Long

المصدر: Molecular Cell. 78:1096-1113.e8

مصطلحات موضوعية: BRD4, Chromosomal Proteins, Non-Histone, Antineoplastic Agents, Cell Cycle Proteins, Triple Negative Breast Neoplasms, Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Mice, Inbred NOD, Cell Line, Tumor, medicine, Animals, Humans, CRISPR, Molecular Biology, Gene, Triple-negative breast cancer, 030304 developmental biology, 0303 health sciences, Chromatin binding, Nuclear Proteins, Proteins, Azepines, Cell Biology, Triazoles, medicine.disease, Bromodomain, Gene Expression Regulation, Neoplastic, Drug Resistance, Neoplasm, Cancer research, Female, 030217 neurology & neurosurgery, Signal Transduction, Transcription Factors, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9800436fa2ce41551e6a7dcef91bbee
https://doi.org/10.1016/j.molcel.2020.04.027

المؤلفون: Chandrajit P. Raut, Matthew A. Lawlor, Jonathan A. Fletcher, Rhamy Zeid, Matthew L. Hemming, George D. Demetri, Ewa Sicinska, James E. Bradner, Frédéric Chibon, Scott A. Armstrong, Tom Lesluyes

مصطلحات موضوعية: 0301 basic medicine, Receptor, Platelet-Derived Growth Factor alpha, Gastrointestinal Stromal Tumors, PDGFRA, Receptor tyrosine kinase, Disease-Free Survival, 03 medical and health sciences, Cell Line, Tumor, Basic Helix-Loop-Helix Transcription Factors, Humans, Epigenetics, Stromal tumor, Enhancer, Transcription factor, neoplasms, Cell Proliferation, Multidisciplinary, biology, GiST, Receptor Protein-Tyrosine Kinases, digestive system diseases, Proto-Oncogene Proteins c-kit, 030104 developmental biology, HEK293 Cells, PNAS Plus, Mutation, Cancer research, biology.protein, Disease Progression, Chromatin immunoprecipitation, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfc2c229ea811c14a2d07da68ef8e38
https://europepmc.org/articles/PMC6016782/

المؤلفون: Volker Hovestadt, Peter Lichter, Linlin Yin, Sebastian M. Waszak, Victor V. Chizhikov, Maia Segura-Wang, Donald R. Polaski, Marc Zapatka, Parthiv Haldipur, Marcel Kool, Andrey Korshunov, James E. Bradner, Paul A. Northcott, Roland Eils, David T.W. Jones, Laura Sieber, Lukas Chavez, Bensheng Ju, Wenbiao Chen, Barbara C. Worst, Yiai Tong, Pascal Johann, Hans Lehrach, Rhamy Zeid, Vyacheslav Amstislavskiy, Serap Erkek, Thomas Risch, Ivo Buchhalter, Stefan M. Pfister, Marie-Laure Yaspo, Stefan Gröschel, Brent A. Orr, Daisuke Kawauchi, Jan O. Korbel, Hans-Jörg Warnatz, Kathleen J. Millen, Marina Ryzhova, Charles Y. Lin, Alexander J. Federation

المصدر: Nature

مصطلحات موضوعية: Male, 0301 basic medicine, Gene regulatory network, Biology, Article, Transcriptome, Mice, 03 medical and health sciences, Genes, Reporter, medicine, Animals, Humans, Gene Regulatory Networks, Cerebellar Neoplasms, Enhancer, Transcription factor, Zebrafish, Regulation of gene expression, Medulloblastoma, Genetics, Multidisciplinary, Reproducibility of Results, medicine.disease, Gene Expression Regulation, Neoplastic, Enhancer Elements, Genetic, 030104 developmental biology, DNA methylation, Female, Chromatin immunoprecipitation, Genes, Neoplasm, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88de35f0b25c0c3ecc0f6f80faa329b
https://doi.org/10.1038/nature16546