المؤلفون: Jerónimo L. Ulloa, Renata Spina, Agustina Casasco, Patricia B. Petray, Virginia Martino, Miguel A. Sosa, Fernanda M. Frank, Liliana V. Muschietti

المصدر: Parasites & Vectors, Vol 10, Iss 1, Pp 1-10 (2017)

مصطلحات موضوعية: Sesquiterpene lactones, Smallanthus sonchifolius, Leishmanicidal activity, Trypanocidal activity, In vitro assays, In vivo assays, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13071-017-2509-6; https://doaj.org/toc/1756-3305

URL الوصول: https://doaj.org/article/b36c688b82e14ca695cdc17f48c53ef2

المؤلفون: Elisa Lombardo, Laura C. Laurella, Valeria P. Sülsen, Esteban Lozano, Vanesa Rocío Puente, Renata Spina, Virginia Martino, Miguel A. Sosa

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: DICHLOROFLUORESCEIN [DCF], ULTRAESTRUCTURAL DAMAGE, Pharmaceutical Science, Apoptosis, Sesquiterpene lactone, Antioxidants, RHODAMINE 123 [RH123], purl.org/becyt/ford/1 [https], Lactones, Sesquiterpenes, Germacrane, 0302 clinical medicine, 2′,7′-DICHLORODIHYDROFLUORESCEIN DIACETATE [H2DCFDA], Drug Discovery, DEOXYMIKANOLIDE, NADH, NADPH Oxidoreductases, OXIDATIVE STRESS, 2,6-DICHLOROPHENOLINDOPHENOL [DCIP], Membrane Potential, Mitochondrial, chemistry.chemical_classification, 0303 health sciences, Glutathione, Trypanocidal Agents, Deoxymikanolide, 5,5′-DITHIOBIS-2-NITROBENZOATE [DTNB], Sterols, 030220 oncology & carcinogenesis, DIMETHYL SULFOXIDE [DMSO], Hemin, Molecular Medicine, SESQUITERPENE LACTONE, CIENCIAS NATURALES Y EXACTAS, MITOCHONDRIAL DYSFUNCTION, TRYPANOTHIONE REDUCTASE [TRYR], Trypanosoma cruzi, REACTIVE OXYGEN SPECIES [ROS], Biology, Ciencias Biológicas, 03 medical and health sciences, Biología Celular, Microbiología, Autophagy, PROPIDIUM IODIDE [PI], SUCCINATE CYTOCHROME C REDUCTASE [SCR], Mikania, purl.org/becyt/ford/1.6 [https], 030304 developmental biology, Pharmacology, Superoxide Dismutase, SUPEROXIDE DISMUTASE [SOD], TRYPANOSOMA CRUZI, biology.organism_classification, Molecular biology, Oxidative Stress, GLUTATHIONE [GSH], Complementary and alternative medicine, chemistry, PHOSPHATE BUFFERED SALINE [PBS]

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa4781a5191e41b7451bed8fb36f6b5
https://doi.org/10.1016/j.phymed.2018.10.015

المؤلفون: Miguel A. Sosa, María Belén Agüero, Esteban Lozano, Renata Spina, Alejandro Tapia, Patricia Barrera, Gabriela Egly Feresin

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

مصطلحات موضوعية: 0301 basic medicine, Chagas disease, Trypanosoma cruzi, 030106 microbiology, Pharmaceutical Science, Mitochondrion, EMBELIN (EMB), purl.org/becyt/ford/1 [https], 03 medical and health sciences, parasitic diseases, Drug Discovery, Chlorocebus aethiops, purl.org/becyt/ford/1.4 [https], medicine, Benzoquinones, Animals, Chagas Disease, Amastigote, Vero Cells, Pharmacology, biology, Chemistry, 2,5-DI-O-METHYLEMBELIN (DME), 5-O-METHYLEMBELIN (ME), Ciencias Químicas, Plasmodium falciparum, TRYPANOSOMA CRUZI, Plants, medicine.disease, Leishmania, biology.organism_classification, Molecular biology, Mitochondria, Química Orgánica, 030104 developmental biology, Complementary and alternative medicine, Mechanism of action, Molecular Medicine, CHAGAS' DISEASE, medicine.symptom, Reactive Oxygen Species, CIENCIAS NATURALES Y EXACTAS, Intracellular

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013238369fc9cce9771b710ded127444
https://pubmed.ncbi.nlm.nih.gov/30097111

المؤلفون: Miguel Angel Sosa, Renata Spina, Patricia Barrera, Carlos E. Tonn, Esteban Lozano

المساهمون: Sülsen, Valeria Patricia, Martino, Virginia Susana

المصدر: Sesquiterpene lactones: Advances in their chemistry and biological aspects
Sesquiterpene Lactones ISBN: 9783319782737

مصطلحات موضوعية: 0301 basic medicine, CIENCIAS MÉDICAS Y DE LA SALUD, 030106 microbiology, 030231 tropical medicine, Sesquiterpene lactone, 03 medical and health sciences, 0302 clinical medicine, parasitic diseases, Organelle, medicine, Cytoskeleton, chemistry.chemical_classification, Membrane budding, Medicina Química, Trypanosomatids ultrastructure, Nuclear DNA, Cell biology, Treatment, Medicina Básica, Neglected diseases, chemistry, Mechanism of action, Kinetoplast, Ultrastructure, medicine.symptom, Sesquiterpene lactones

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7db9c1de8c8f68bd313164bb3f1a212
https://link.springer.com/chapter/10.1007/978-3-319-78274-4_11