المؤلفون: Frederick Arce Vargas (8985050), Andrew JS Furness (8985053), Isabelle Solomon (7783973), Kroopa Joshi (7783976), Leila Mekkaoui (7783979), Marta H Lesko (8985059), Enrique Miranda Rota (11284629), Rony Dahan (7783988), Andrew Georgiou (4355617), Anna Sledzinska (7783991), Assma Ben Aissa (8985071), Dafne Franz (7783997), Mariana Werner Sunderland (9573455), Yien Ning Sophia Wong (7784003), Jake Y Henry (8985065), Tim O'Brien (7784009), David Nicol (4458523), Ben Challacombe (4265254), Stephen A Beers (11284632), Melanoma TRACERx Consortium (7784012), Renal TRACERx Consortium (7784015), Lung TRACERx Consortium (7784018), Samra Turajlic (7784021), Martin Gore (3570650), James Larkin (715545), Charles Swanton (236153), Kerry A Chester (11284635), Martin Pule (821995), Jeffrey V Ravetch (11284638), Teresa Marafioti (7741250), Karl S Peggs (8985086), Sergio A Quezada (8985089)

مصطلحات موضوعية: Ecology,Evolution & Ethology, Computational & Systems Biology, Model organisms, Tumour Biology, Signalling & Oncogenes, Gene Expression, Genetics & Genomics, Developmental Biology, Genome Integrity & Repair, Human Biology & Physiology, Chemical Biology & High Throughput, CD25, Fc gamma receptors, Treg depletion, anti-CD25, anti-PD-1, inhibitory Fc receptor, regulatory T cells, tumor immunotherapy, tumor microenvironment, Animals, Antibodies, Monoclonal, Cell Line, Tumor, Flow Cytometry, Humans, Immunoglobulin Fc Fragments, Immunotherapy, Interleukin-2 Receptor alpha Subunit

Relation: https://figshare.com/articles/journal_contribution/Fc-optimized_anti-CD25_depletes_tumor-infiltrating_regulatory_T_cells_and_synergizes_with_PD-1_blockade_to_eradicate_established_tumors/15180285

الاتاحة: https://doi.org/10.25418/crick.15180285.v1