المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/journal_contribution/S1_Checklist_-/14341259

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.s001

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/journal_contribution/MEDLINE_search_strategy_/14341262

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.s002

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/journal_contribution/Forest_plots_/14341265

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.s003

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/figure/All-cause_mortality_assessed_with_risk_of_death_all_from_observational_studies_/14341277

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.g004

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/figure/Eligibility_assessment_PRISMA_flow_diagram_/14341268

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.g001

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/figure/Risk_of_bias_in_observational_studies_/14341271

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.g002

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/figure/Risk_of_bias_in_RCTs_/14341274

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.g003

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/dataset/GRADE_summary_of_findings_Intensive_versus_less-intensive_antileukemic_therapy_among_older_patients_with_acute_myeloid_leukemia_evidence_from_RCTs_/14341289

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.t003

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/figure/Funnel_plot_to_detect_publication_bias_/14341280

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.g005

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/dataset/Characteristics_of_included_studies_/14341283

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.t001

المؤلفون: Yaping Chang (4683223), Gordon H. Guyatt (9501499), Trevor Teich (539021), Jamie L. Dawdy (10499387), Shaneela Shahid (10499390), Jessica K. Altman (10499393), Richard M. Stone (2555110), Mikkael A. Sekeres (9122702), Sudipto Mukherjee (1458646), Thomas W. LeBlanc (10499396), Gregory A. Abel (4433521), Christopher S. Hourigan (6205955), Mark R. Litzow (4624528), Laura C. Michaelis (10499399), Shabbir M. H. Alibhai (9545898), Pinkal Desai (10499402), Rena Buckstein (10499405), Janet MacEachern (10499408), Romina Brignardello-Petersen (814592)

مصطلحات موضوعية: Medicine, Pharmacology, Biotechnology, Ecology, Cancer, Science Policy, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, less-intensive antileukemic therapy, RR, studies enrolling 7296 patients, HR, AML, antileukemic therapy, Low certainty evidence, MD, CI, CENTRAL, hypomethylating agent-based chemoth., cytarabine, myeloid leukemia, care unit hospitalization, randomized trials enrolling 529 pat., less-intensive therapy

Relation: https://figshare.com/articles/dataset/GRADE_summary_of_findings_Intensive_versus_less-intensive_antileukemic_therapy_among_older_patients_with_acute_myeloid_leukemia_evidence_from_observational_studies_/14341286

الاتاحة: https://doi.org/10.1371/journal.pone.0249087.t002