المؤلفون: Chen Jiang (200126), Hao Liu (12832), Jun Wang (5906), Xiaomin Ren (2140453), Qi Wang (22418), Zhuoliang Liu (2315371), Bojie Ma (14414979), Kai Liu (159026), Ren Ren (59774), Yidong Zhang (4528342)

مصطلحات موضوعية: Physics (arXiv), physics.optics (arXiv), physics.app-ph (arXiv)

Relation: https://figshare.com/articles/preprint/Demonstration_of_room-temperature_continuous-wave_operation_of_InGaAs_AlGaAs_quantum_well_lasers_directly_grown_on_on-axis_silicon_001_/21887085

الاتاحة: https://doi.org/10.48550/arxiv.2204.01462

المؤلفون: Jujun Zhou (11435640), John R. Horton (8943), Dan Yu (214174), Ren Ren (59774), Robert M. Blumenthal (11435643), Xing Zhang (11943), Xiaodong Cheng (8947)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Pharmacology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, S-adenosyl-l-methionine analogues, dot1L inhibitors, PRMT inhibitors, pseudomembranous colitis

Relation: https://figshare.com/articles/journal_contribution/Repurposing_epigenetic_inhibitors_to_target_the_i_Clostridioides_difficile-_i_specific_DNA_adenine_methyltransferase_and_sporulation_regulator_CamA/16622106

الاتاحة: https://doi.org/10.6084/m9.figshare.16622106.v1

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843308

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s010

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843281

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s001

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843284

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s002

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843287

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s003

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843290

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s004

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843293

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s005

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843296

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s006

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843299

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s007

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843305

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s009

المؤلفون: Lufeng Zheng (4668964), Ren Ren (59774), Xiaolian Sun (1306611), Yunting Zou (11590656), Yiru Shi (11407281), Bin Di (2070112), Miao-Miao Niu (11590659)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vivo assessment indicates, notable side effects, cellular assays reveal, cell cycle arrest, based pharmacophore modeling, 231 xenograft tumors, toxic antitumor agent, human cancer cells, based virtual screening, poly ­( adp, virtual screening, cancer therapy, antitumor role, tube formation, studies indicate, strand breaks, nude mouse, multiple mechanisms

Relation: https://figshare.com/articles/dataset/Discovery_of_a_Dual_Tubulin_and_Poly_ADP-Ribose_Polymerase_1_Inhibitor_by_Structure-Based_Pharmacophore_Modeling_Virtual_Screening_Molecular_Docking_and_Biological_Evaluation/16843302

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00932.s008

المؤلفون: Jujun Zhou (11435640), John R. Horton (8943), Martina Menna (11500879), Francesco Fiorentino (8736915), Ren Ren (59774), Dan Yu (214174), Taraneh Hajian (1294986), Masoud Vedadi (210076), Giulia Mazzoccanti (5363576), Alessia Ciogli (828628), Elmar Weinhold (2453569), Michael Hüben (14309950), Robert M. Blumenthal (11435643), Xing Zhang (11943), Antonello Mai (205768), Dante Rotili (462382), Xiaodong Cheng (8947)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Evolutionary Biology, Infectious Diseases, Chemical Sciences not elsewhere classified, rna adenine methyltransferases, 2 μm ), sam adenosine moiety, human adenosine receptors, adenosine carrying substituents, clostridioides difficile -<, clostridioides difficile <, closely related bacterial, 50 , 39 , difficile -<, closely resembles, arginine methyltransferases, 4 μm, adenosine analogs, k <, , ∼ 0, urgently needed, substrate dna, protein lysine

Relation: https://figshare.com/articles/journal_contribution/Systematic_Design_of_Adenosine_Analogs_as_Inhibitors_of_a_i_Clostridioides_difficile-_i_Specific_DNA_Adenine_Methyltransferase_Required_for_Normal_Sporulation_and_Persistence/21791812

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01789.s002

المؤلفون: Jujun Zhou (11435640), John R. Horton (8943), Martina Menna (11500879), Francesco Fiorentino (8736915), Ren Ren (59774), Dan Yu (214174), Taraneh Hajian (1294986), Masoud Vedadi (210076), Giulia Mazzoccanti (5363576), Alessia Ciogli (828628), Elmar Weinhold (2453569), Michael Hüben (14309950), Robert M. Blumenthal (11435643), Xing Zhang (11943), Antonello Mai (205768), Dante Rotili (462382), Xiaodong Cheng (8947)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Evolutionary Biology, Infectious Diseases, Chemical Sciences not elsewhere classified, rna adenine methyltransferases, 2 μm ), sam adenosine moiety, human adenosine receptors, adenosine carrying substituents, clostridioides difficile -<, clostridioides difficile <, closely related bacterial, 50 , 39 , difficile -<, closely resembles, arginine methyltransferases, 4 μm, adenosine analogs, k <, , ∼ 0, urgently needed, substrate dna, protein lysine

Relation: https://figshare.com/articles/dataset/Systematic_Design_of_Adenosine_Analogs_as_Inhibitors_of_a_i_Clostridioides_difficile-_i_Specific_DNA_Adenine_Methyltransferase_Required_for_Normal_Sporulation_and_Persistence/21791809

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01789.s001