نتائج البحث - "Recombinant Proteins* / therapeutic use"

1

Academic Journal

Taldefgrobep Alfa and the Phase 3 RESILIENT Trial in Spinal Muscular Atrophy.

المؤلفون: Servais, Laurent, Lair, Lindsey Lee, Connolly, Anne M, Byrne, Barry J, Chen, Karen S, Coric, Vlad, Qureshi, Irfan, Durham, Susan, Campbell, Daniel J, Maclaine, Grant, Marin, Jackie, Bechtold, Clifford

المصدر: International Journal of Molecular Sciences, 25 (19), 10273 (2024-09-24)

مصطلحات موضوعية: RESILIENT, SMA, SMN upregulation, SMN upregulator, antimyostatin, myostatin, myostatin inhibitor, phase 3 clinical trial, spinal muscular atrophy, taldefgrobep, Myostatin, Activin Receptors, Type II, MSTN protein, human, Recombinant Proteins, Humans, Clinical Trials, Phase III as Topic, Activin Receptors, Type II/metabolism, Activin Receptors, Type II/therapeutic use, Animals, Recombinant Proteins/therapeutic use, Myostatin/metabolism, Myostatin/antagonists & inhibitors, Muscular Atrophy, Spinal/metabolism, Muscular Atrophy, Spinal/drug therapy, Muscular Atrophy, Spinal/genetics, Muscular Atrophy, Spinal, Catalysis, Molecular Biology, Spectroscopy, Computer Science Applications, Physical and Theoretical Chemistry, Organic Chemistry, Inorganic Chemistry, Human health sciences, Pediatrics, Sciences de la santé humaine, Pédiatrie

Relation: https://www.mdpi.com/1422-0067/25/19/10273/pdf; urn:issn:1661-6596; urn:issn:1422-0067

URL الوصول: https://orbi.uliege.be/handle/2268/324878

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2

Academic Journal

Long-acting recombinant human follicle-stimulating hormone (SAFA-FSH) enhances spermatogenesis

المساهمون: Daham Kim, Soohyun Lee, Yoon Hee Cho, Min Jeong Kang, Cheol Ryong Ku, Hyunjin Chi, Jungsuk Ahn, Kyungsun Lee, Jaekyu Han, Susan Chi, Moo Young Song, Sang-Hoon Cha, Eun Jig Lee, Ku, Cheol Ryong

Relation: FRONTIERS IN ENDOCRINOLOGY; J03412; OAK-2023-00803; OAK-2023-00804; OAK-2023-00805; OAK-2023-00806; https://ir.ymlib.yonsei.ac.kr/handle/22282913/194126; T202302283; FRONTIERS IN ENDOCRINOLOGY, Vol.14 : 1132172, 2023-02

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/194126
https://doi.org/10.3389/fendo.2023.1132172

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3

Academic Journal

Concentration-Dependent Efficacy of Recombinant Human Bone Morphogenetic Protein-2 Using a HA/β-TCP Hydrogel Carrier in a Mini-Pig Vertebral Oblique Lateral Interbody Fusion Model

المساهمون: Hye-Yeong Lee, Ji-In Kang, Hye-Lan Lee, Gwang-Yong Hwang, Keung-Nyun Kim, Yoon Ha, Kang, Jiin

مصطلحات موضوعية: Animals, Bone Morphogenetic Protein 2* / therapeutic use, Humans, Hydrogels, Recombinant Proteins* / therapeutic use, Spinal Fusion* / methods, Swine, Miniature, Transforming Growth Factor beta / pharmacology, HA/β-TCP hydrogel putty, oblique lateral interbody fusion model, recombinant human bone morphogenetic protein-2

وصف الملف: application/pdf

Relation: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; J01133; OAK-2022-10943; OAK-2022-10944; OAK-2022-10945; https://ir.ymlib.yonsei.ac.kr/handle/22282913/193578; T202300928; INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.24(1) : 892, 2023-01

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/193578
https://doi.org/10.3390/ijms24010892

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4

Academic Journal

Adherence to protocols for the use of reversal agents in patients treated with direct oral anticoagulants

المؤلفون: Mitrovic, Darko, van Elp, Margriet, Visser, Loes, van Rein, Nienke, van den Bemt, Patricia, van Hulst, Marinus, Dreijer, Albert, Lameijer, Heleen, Veeger, Nic, Meijer, Karina, van Roon, Eric

المصدر: Mitrovic , D , van Elp , M , Visser , L , van Rein , N , van den Bemt , P , van Hulst , M , Dreijer , A , Lameijer , H , Veeger , N , Meijer , K & van Roon , E 2023 , ' Adherence to protocols for the use of reversal agents in patients treated with direct oral anticoagulants ' , Current Medical Research and Opinion , vol. 39 , no. 6 , pp. 865-871 . https://doi.org/10.1080/03007995.2023.2204767

مصطلحات موضوعية: Humans, Anticoagulants/adverse effects, Retrospective Studies, Hemorrhage/drug therapy, Dabigatran/therapeutic use, Clinical Protocols, Administration, Oral, Recombinant Proteins/therapeutic use

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/edbc8ce4-0f2d-429b-90f4-e3bd09b3cc27
https://research.rug.nl/en/publications/edbc8ce4-0f2d-429b-90f4-e3bd09b3cc27
https://doi.org/10.1080/03007995.2023.2204767
https://pure.rug.nl/ws/files/731181824/Adherence_to_protocols_for_the_use_of_reversal_agents_in_patients_treated_with_direct_oral_anticoagulants.pdf

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5

Academic Journal

Mechanisms of Neutralizing Anti-drug Antibody Formation and Clinical Relevance on Therapeutic Efficacy of Enzyme Replacement Therapies in Fabry Disease

المؤلفون: Lenders, Malte, Brand, Eva

المصدر: http://lobid.org/resources/99370676914906441#!, 81(17):1969-1981.

مصطلحات موضوعية: Pharmacology/Toxicology, Fabry Disease/physiopathology [MeSH], alpha-Galactosidase/adverse effects [MeSH], Enzyme Replacement Therapy/adverse effects [MeSH], Humans [MeSH], alpha-Galactosidase/therapeutic use [MeSH], Enzyme Replacement Therapy/methods [MeSH], Review Article, Trihexosylceramides/metabolism [MeSH], Isoenzymes/adverse effects [MeSH], Risk Factors [MeSH], Lysosomal Storage Diseases/pathology [MeSH], Injection Site Reaction [MeSH], Recombinant Proteins/adverse effects [MeSH], Recombinant Proteins/therapeutic use [MeSH], Antibodies, Neutralizing/immunology [MeSH], Antibody Formation [MeSH], Male [MeSH], Fabry Disease/drug therapy [MeSH], Isoenzymes/therapeutic use [MeSH], Internal Medicine, Pharmacotherapy

Relation: https://repository.publisso.de/resource/frl:6465085; https://doi.org/10.1007/s40265-021-01621-y; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602155/

الاتاحة: https://repository.publisso.de/resource/frl:6465085
https://doi.org/10.1007/s40265-021-01621-y
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602155/

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6

Academic Journal

Growth hormone treatment in the pre-transplant period is associated with superior outcome after pediatric kidney transplantation

المؤلفون: Jagodzinski, Celina, Mueller, Sophia, Kluck, Rika, Froede, Kerstin, Pavičić, Leo, Gellermann, Jutta, Mueller, Dominik, Querfeld, Uwe, Haffner, Dieter, zivicnjak, miroslav

المصدر: http://lobid.org/resources/99370671682606441#!, 37(4):859-869.

Relation: https://repository.publisso.de/resource/frl:6449734; https://doi.org/10.1007/s00467-021-05222-5; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960657/

الاتاحة: https://repository.publisso.de/resource/frl:6449734
https://doi.org/10.1007/s00467-021-05222-5
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960657/

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7

Academic Journal

Addressing the ‘hypoxia paradox’ in severe COVID-19: literature review and report of four cases treated with erythropoietin analogues

المؤلفون: Begemann, Martin, Gross, Oliver, Wincewicz, Dominik, Hardeland, Ruediger, Daguano Gastaldi, Vinicius, Vieta, Eduard, Weissenborn, Karin, Miskowiak, Kamilla, Moerer, Onnen, Ehrenreich, Hannelore

المصدر: http://lobid.org/resources/99370697365106441#!, 27(1):120.

Relation: https://repository.publisso.de/resource/frl:6442398; https://doi.org/10.1186/s10020-021-00381-5; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474703/

الاتاحة: https://repository.publisso.de/resource/frl:6442398
https://doi.org/10.1186/s10020-021-00381-5
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8474703/

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8

Academic Journal

Efficacy and safety of the recombinant human growth hormone in short children born small for gestational age: A randomized, multicentre, comparative phase III trial

المساهمون: Su Jin Kim, Min-Sun Kim, Sung Yoon Cho, Byung-Kyu Suh, Cheol Woo Ko, Kee-Hyoung Lee, Han-Wook Yoo, Choong Ho Shin, Jin Soon Hwang, Ho-Seong Kim, Woo Yeong Chung, Chan Jong Kim, Heon-Seok Han, Dong-Kyu Jin, Kim, Ho Seong

مصطلحات موضوعية: Child, Preschool, Female, Human Growth Hormone / therapeutic use, Humans, Infant, Newborn, Small for Gestational Age, Male, Recombinant Proteins / therapeutic use

Relation: MEDICINE; J02214; OAK-2021-08162; https://ir.ymlib.yonsei.ac.kr/handle/22282913/187034; T202104953; MEDICINE, Vol.100(30) : e26711, 2021-07

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/187034
https://doi.org/10.1097/MD.0000000000026711

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9

Academic Journal

Rate of progression of hepatic fibrosis in patients with chronic hepatitis C: results from the HALT-C Trial.

المؤلفون: Hoefs, John C, Shiffman, Mitchell L, Goodman, Zachary D, Kleiner, David E, Dienstag, Jules L, Stoddard, Anne M

المصدر: Gastroenterology. 141(3)

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0f72w504

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10

Academic Journal

The effect of enzyme replacement therapy on clinical outcomes in female patients with Fabry disease - A systematic literature review by a European panel of experts

المؤلفون: Germain, Dominique P, Arad, Michael, Burlina, Alessandro, Elliott, Perry M, Falissard, Bruno, Feldt-Rasmussen, Ulla, Hilz, Max J, Hughes, Derralynn A, Ortiz, Alberto, Wanner, Christoph, Weidemann, Frank, Spada, Marco

المصدر: Germain , D P , Arad , M , Burlina , A , Elliott , P M , Falissard , B , Feldt-Rasmussen , U , Hilz , M J , Hughes , D A , Ortiz , A , Wanner , C , Weidemann , F & Spada , M 2019 , ' The effect of enzyme replacement therapy on clinical outcomes in female patients with Fabry disease - A systematic literature review by a European panel of experts ' , Molecular Genetics and Metabolism , vol. 126 , no. 3 , pp. 224-235 . https://doi.org/10.1016/j.ymgme.2018.09.007

مصطلحات موضوعية: Clinical Trials as Topic, Enzyme Replacement Therapy, Fabry Disease/therapy, Female, Gastrointestinal Tract, Humans, Isoenzymes/therapeutic use, Nervous System, Observational Studies as Topic, Pain, Quality of Life, Recombinant Proteins/therapeutic use, Treatment Outcome, Trihexosylceramides/blood, alpha-Galactosidase/therapeutic use

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/the-effect-of-enzyme-replacement-therapy-on-clinical-outcomes-in-female-patients-with-fabry-disease--a-systematic-literature-review-by-a-european-panel-of-experts(d3d04c32-1725-498b-8da1-54bfd0fa0cf9).html
https://doi.org/10.1016/j.ymgme.2018.09.007
https://curis.ku.dk/ws/files/234450079/1_s2.0_S1096719218301926_main.pdf

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11

Academic Journal

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

المؤلفون: Tian, Weihua, Ye, Zilu, Wang, Shengjun, Schulz, Morten Alder, Van Coillie, Julie, Sun, Lingbo, Chen, Yen-Hsi, Narimatsu, Yoshiki, Hansen, Lars, Kristensen, Claus, Mandel, Ulla, Bennett, Eric Paul, Jabbarzadeh-Tabrizi, Siamak, Schiffmann, Raphael, Shen, Jin-Song, Vakhrushev, Sergey Y., Clausen, Henrik, Yang, Zhang

المصدر: Tian , W , Ye , Z , Wang , S , Schulz , M A , Van Coillie , J , Sun , L , Chen , Y-H , Narimatsu , Y , Hansen , L , Kristensen , C , Mandel , U , Bennett , E P , Jabbarzadeh-Tabrizi , S , Schiffmann , R , Shen , J-S , Vakhrushev , S Y , Clausen , H & Yang , Z 2019 , ' The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells ' , Nature Communications , vol. 10 , ....

مصطلحات موضوعية: Animals, CHO Cells, Cricetinae, Cricetulus, Disease Models, Animal, Fabry Disease/drug therapy, Glycosylation, Lysosomes/enzymology, Male, Mice, Knockout, Recombinant Proteins/therapeutic use, alpha-Galactosidase/therapeutic use

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/the-glycosylation-design-space-for-recombinant-lysosomal-replacement-enzymes-produced-in-cho-cells(3e2a06f8-14f4-4325-8421-d29ab3624404).html
https://doi.org/10.1038/s41467-019-09809-3
https://curis.ku.dk/ws/files/226257323/The_glycosylation_design_space_for_recombinant_lysosomal_replacement_enzymes_produced_in_CHO_cells.pdf

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12

Academic Journal

Prenatal Correction of X-Linked Hypohidrotic Ectodermal Dysplasia.

المؤلفون: Schneider, H., Faschingbauer, F., Schuepbach-Mallepell, S., Körber, I., Wohlfart, S., Dick, A., Wahlbuhl, M., Kowalczyk-Quintas, C., Vigolo, M., Kirby, N., Tannert, C., Rompel, O., Rascher, W., Beckmann, M.W., Schneider, P.

المصدر: The New England Journal of Medicine, vol. 378, no. 17, pp. 1604-1610

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/29694819; info:eu-repo/semantics/altIdentifier/eissn/1533-4406; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_7D5E9C7A775B4; https://serval.unil.ch/notice/serval:BIB_7D5E9C7A775B; https://serval.unil.ch/resource/serval:BIB_7D5E9C7A775B.P001/REF.pdf

الاتاحة: https://serval.unil.ch/notice/serval:BIB_7D5E9C7A775B
https://doi.org/10.1056/NEJMoa1714322
https://serval.unil.ch/resource/serval:BIB_7D5E9C7A775B.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_7D5E9C7A775B4

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13

Academic Journal

An Observational, Multicenter, Cohort Study Evaluating the Antiviral Efficacy and Safety in Korean Patients with Chronic Hepatitis B Receiving Pegylated Interferon-Alpha 2a (Pegasys)

المساهمون: College of Medicine, Dept. of Internal Medicine, Young Eun Chon, Dong Joon Kim, Sang Gyune Kim, In Hee Kim, Si Hyun Bae, Seong Gyu Hwang, Jeong Heo, Jeong Won Jang, Byung Seok Lee, Hyung Joon Kim, Dae Won Jun, Kang Mo Kim, Woo Jin Chung, Moon Seok Choi, Jae Young Jang, Hyung Joon Yim, Won Young Tak, Ki Tae Yoon, Jun Yong Park, Kwang-Hyub Han, Ki Tae Suk, Hyun Woong Lee, Byoung Kuk Jang, Sang Hoon Ahn, Park, Jun Yong, Ahn, Sang Hoon, Han, Kwang Hyup

مصطلحات موضوعية: Adult, Antiviral Agents/therapeutic use, Cohort Studies, Female, Hepatitis B e Antigens/blood, Hepatitis B, Chronic/blood, Chronic/drug therapy, Humans, Interferon-alpha/therapeutic use, Male, Polyethylene Glycols/therapeutic use, Recombinant Proteins/therapeutic use, Republic of Korea, Treatment Outcome

Relation: MEDICINE; J02214; OAK-2016-08731; https://ir.ymlib.yonsei.ac.kr/handle/22282913/153132; T201606283; MEDICINE, Vol.95(14) : 3026, 2016

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/153132
https://doi.org/10.1097/MD.0000000000003026

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14

Academic Journal

Clinical Utility of a New Automated Hepatitis C Virus Core Antigen Assay for Prediction of Treatment Response in Patients with Chronic Hepatitis C

المساهمون: College of Medicine, Dept. of Internal Medicine, Mi Na Kim, Hyon-Suk Kim, Ja Kyung Kim, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Kim, Do Young, Kim, Beom Kyung, Kim, Seung Up, Kim, Ja Kyung, Kim, Hyon Suk, Park, Jun Yong, Ahn, Sang Hoon, Han, Kwang Hyup

Relation: JOURNAL OF KOREAN MEDICAL SCIENCE; J01517; OAK-2016-06768; https://ir.ymlib.yonsei.ac.kr/handle/22282913/152482; T201604458; JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.31(9) : 1431-1437, 2016

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/152482
https://doi.org/10.3346/jkms.2016.31.9.1431

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15

Academic Journal

Estimation of direct medical cost related to the management of chronic hepatitis C and its complications in South Korea

المساهمون: College of Medicine, Dept. of Internal Medicine, Do Young Kim, Ki Tae Yoon, Won Kim, Jung Il Lee, Sung Hwi Hong, Danbi Lee, Jeong Won Jang, Jong Won Choi, Ilsu Kim, Yong Han Paik, Kim, Do Young, Lee, Jung Il

Relation: MEDICINE; J02214; OAK-2016-04516; https://ir.ymlib.yonsei.ac.kr/handle/22282913/151802; T201602917; MEDICINE, Vol.95(30) : 3896, 2016

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/151802
https://doi.org/10.1097/MD.0000000000003896

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16

Academic Journal

Programmed cell death ligand 1 alleviates psoriatic inflammation by suppressing IL-17A production from programmed cell death 1-high T cells.

المساهمون: College of Medicine, Yonsei Biomedical Research Center, Jong Hoon Kim, Young Joon Choi, Byung Ha Lee, Mi-Young Song, Chae Yeon Ban, Jihye Kim, Junsik Park, Song-Ee Kim, Tae-Gyun Kim, Su-Hyung Park, Hyoung-Pyo Kim, Young-Chul Sung, Soo-Chan Kim, Eui-Cheol Shin, Kim, Song Ee, Kim, Soo Chan, Kim, Hyoung Pyo, Kim, Jong Hoon

وصف الملف: 1466~1476

Relation: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY; J01228; OAK-2016-02946; https://ir.ymlib.yonsei.ac.kr/handle/22282913/147037; http://www.sciencedirect.com/science/article/pii/S0091674916000221; T201601970; JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Vol.137(5) : 1466-1476, 2016

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/147037
https://doi.org/10.1016/j.jaci.2015.11.021
http://www.sciencedirect.com/science/article/pii/S0091674916000221

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17

Academic Journal

Predicting Liver-Related Events Using Transient Elastography in Chronic Hepatitis C Patients with Sustained Virological Response.

المساهمون: College of Medicine, Dept. of Internal Medicine, Hye Won Lee, Young Eun Chon, Seung Up Kim, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kyu Sik Jung, Young Nyun Park, Kwang-Hyub Han, Kim, Do Young, Kim, Seung Up, Park, Young Nyun, Park, Jun Yong, Ahn, Sang Hoon, Chon, Young Eun, Jung, Kyu Sik, Han, Kwang Hyup, Kim, Beom Kyung, Lee, Hye Won

وصف الملف: 429~436

Relation: GUT AND LIVER; J00954; OAK-2016-02044; https://ir.ymlib.yonsei.ac.kr/handle/22282913/146781; T201601289; GUT AND LIVER, Vol.10(3) : 429-436, 2016

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/146781
https://doi.org/10.5009/gnl15021

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18

Academic Journal

Bone Regenerative Efficacy of Limited-Dose Escherichia Coli-Derived rhBMP-2 With Biphasic Calcium Phosphate Carrier in Rabbit Calvarial Defect Model.

المساهمون: College of Dentistry, Dept. of Periodontology, Hoon You, So-Ra Yoon, Hyun-Chang Lim, Jung-Seok Lee, Ui-Won Jung, Seong-Ho Choi, You, Hoon, Lee, Jung Seok, Jung, Ui Won, Choi, Seong Ho

مصطلحات موضوعية: Animals, Bone Morphogenetic Protein 2/therapeutic use, Bone Regeneration/drug effects, Escherichia coli/metabolism, Hydroxyapatites/therapeutic use, Male, Rabbits, Recombinant Proteins/therapeutic use, Skull/growth & development, X-Ray Microtomography, biphasic calcium phosphate, bone morphogenetic protein 2, bone regeneration, bone substitutes, rabbit calvaria