المؤلفون: Aleksandra Beylina, Rebekah G. Langston, Dorien Rosen, Xylena Reed, Mark R. Cookson

المصدر: Stem Cell Research, Vol 53, Iss , Pp 102354- (2021)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506121002002; https://doaj.org/toc/1873-5061

URL الوصول: https://doaj.org/article/42d02b2bdece4ed4a79b1abbcd8a022a

المؤلفون: David N. Hauser, Adamantios Mamais, Melissa M. Conti, Christopher T. Primiani, Ravindran Kumaran, Allissa A. Dillman, Rebekah G. Langston, Alexandra Beilina, Joseph H. Garcia, Alberto Diaz-Ruiz, Michel Bernier, Fabienne C. Fiesel, Xu Hou, Wolfdieter Springer, Yan Li, Rafael de Cabo, Mark R. Cookson

المصدر: Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-17 (2017)

مصطلحات موضوعية: Proteomics, RNA-Seq, Metabolomics, Systems biology, Parkinson’s disease, Mitophagy, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13024-017-0212-x; https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/dfb1e3bfdb1b4d30a14773c86e3340df

المؤلفون: Rebekah G. Langston, Tuhin Virmani

المصدر: Frontiers in Neurology, Vol 9 (2018)

مصطلحات موضوعية: Parkinson's disease, visual loss, diagnostic test assessment, early marker of disease, color vision dysfunction, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fneur.2018.00765/full; https://doaj.org/toc/1664-2295

URL الوصول: https://doaj.org/article/6bdcdf17fc7d4151b4e55d88f0d33109

المؤلفون: Marc Emmenegger, Elena De Cecco, Marian Hruska‐Plochan, Timo Eninger, Matthias M Schneider, Melanie Barth, Elena Tantardini, Pierre de Rossi, Mehtap Bacioglu, Rebekah G Langston, Alice Kaganovich, Nora Bengoa‐Vergniory, Andrès Gonzalez‐Guerra, Merve Avar, Daniel Heinzer, Regina Reimann, Lisa M Häsler, Therese W Herling, Naunehal S Matharu, Natalie Landeck, Kelvin Luk, Ronald Melki, Philipp J Kahle, Simone Hornemann, Tuomas P J Knowles, Mark R Cookson, Magdalini Polymenidou, Mathias Jucker, Adriano Aguzzi

المصدر: EMBO Molecular Medicine, Vol 13, Iss 9, Pp 1-20 (2021)

مصطلحات موضوعية: LAG3, neurodegeneration, prionoids, α‐synuclein, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

URL الوصول: https://doaj.org/article/7994f076bf964ea9bf26f7f4ba6a434a

المؤلفون: Adamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, Natalie Landeck, Rebekah G Langston, Nathan Smith, Alexandra Beilina, Alice Kaganovich, Manik C Ghosh, Laura Pellegrini, Ravindran Kumaran, Ioannis Papazoglou, George R Heaton, Kirsten Harvey, Rina Bandopadhyay, Nunziata Maio, Changyoun Kim, Matthew J LaVoie, David C Gershlick, Mark R Cookson

المصدر: PLoS Biology, Vol 20, Iss 5, p e3001621 (2022)

مصطلحات موضوعية: Biology (General), QH301-705.5

Relation: https://doi.org/10.1371/journal.pbio.3001621; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885; https://doaj.org/article/0cfb6188812b44e8a7612e5d6a062027

الاتاحة: https://doi.org/10.1371/journal.pbio.3001621
https://doaj.org/article/0cfb6188812b44e8a7612e5d6a062027

المؤلفون: Adamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, Natalie Landeck, Rebekah G Langston, Nathan Smith, Alexandra Beilina, Alice Kaganovich, Manik C Ghosh, Laura Pellegrini, Ravindran Kumaran, Ioannis Papazoglou, George R Heaton, Rina Bandopadhyay, Nunziata Maio, Changyoun Kim, Matthew J LaVoie, David C Gershlick, Mark R Cookson

المصدر: PLoS Biology, Vol 19, Iss 12, p e3001480 (2021)

مصطلحات موضوعية: Biology (General), QH301-705.5

Relation: https://doi.org/10.1371/journal.pbio.3001480; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885; https://doaj.org/article/71c689db45394c029f869d5ffc9ae238

الاتاحة: https://doi.org/10.1371/journal.pbio.3001480
https://doaj.org/article/71c689db45394c029f869d5ffc9ae238

المؤلفون: Rebekah G. Langston, Alexandra Beilina, Xylena Reed, Alice Kaganovich, Andrew B. Singleton, Cornelis Blauwendraat, J. Raphael Gibbs, Mark R. Cookson

المصدر: Sci Transl Med

مصطلحات موضوعية: Substantia Nigra, Humans, Parkinson Disease, Microglia, General Medicine, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Article, Genome-Wide Association Study

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864508c783f52984465bc6e8cc1f11f4
https://doi.org/10.1126/scitranslmed.abp8869

المؤلفون: Hayden Scott, Analiz Rodriguez, Christopher P. Wardell, Rebekah G. Langston, Murat Gokden, Angela Palmer, T. Glenn Pait

المصدر: Neuro-oncology Advances

مصطلحات موضوعية: Primary Glioblastoma, Pathology, medicine.medical_specialty, Nerve root, business.industry, glioblastoma, Cauda equina, medicine.disease, medicine.anatomical_structure, cauda equina, medicine, AcademicSubjects/MED00300, AcademicSubjects/MED00310, Molecular Tumor Board Case Report, nerve root entry zone, business, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00f9d153963b4d5968ccb2976d141e7
https://pubmed.ncbi.nlm.nih.gov/34765976

المؤلفون: Adriano Aguzzi, Mathias Jucker, Magdalini Polymenidou, Mark R. Cookson, Tuomas P. J. Knowles, Simone Hornemann, Philipp J. Kahle, Ronald Melki, Kelvin Luk, Natalie Landeck, Naunehal S. Matharu, Therese W. Herling, Lisa M. Häsler, Regina Reimann, Daniel Heinzer, Merve Avar, Andrès Gonzalez-Guerra, Nora Bengoa-Vergniory, Alice Kaganovich, Rebekah G. Langston, Mehtap Bacioglu, Pierre de Rossi, Elena Tantardini, Melanie Barth, Matthias M. Schneider, Timo Eninger, Marian Hruska-Plochan, Elena De Cecco, Marc Emmenegger

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7fcdc8bbb95533537cf9843e591965a2
https://doi.org/10.15252/rc.2022275692

المؤلفون: Pierre De Rossi, Therese W. Herling, Marian Hruska-Plochan, Nora Bengoa-Vergniory, Ronald Melki, Natalie Landeck, Mathias Jucker, Simone Hornemann, Philipp J. Kahle, Rebekah G. Langston, Andrés González-Guerra, Merve Avar, Melanie Barth, Timo Eninger, Lisa M. Häsler, Kelvin C. Luk, Mehtap Bacioglu, Daniel Heinzer, Elena Tantardini, Marc Emmenegger, Tuomas P. J. Knowles, Magdalini Polymenidou, Elena De Cecco, Alice Kaganovich, Matthias Schneider, Naunehal S. Matharu, Mark R. Cookson, Adriano Aguzzi, Regina Reimann

مصطلحات موضوعية: Genetically modified mouse, Synucleinopathies, 0303 health sciences, LAG3, Hippocampal slice, Biology, Fibril, Immune checkpoint, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Receptor, 030217 neurology & neurosurgery, Ex vivo, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd694eabd8cc6283df3874908afc5fa9
https://doi.org/10.1101/2021.04.25.441302

المؤلفون: Rebekah G. Langston, Mike A. Nalls, AB Singleton, Leonard H, Julie Lake, Mark R. Cookson, Ziv Gan-Or, Cornelis Blauwendraat, Xylena Reed

مصطلحات موضوعية: Genetics, Linkage disequilibrium, Parkinson's disease, Haplotype, Genotype, medicine, Missense mutation, Genome-wide association study, Disease, Biology, medicine.disease, LRRK2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::68762ca8b846ec687401d425f51d1abf
https://doi.org/10.1101/2021.04.22.21255928

المؤلفون: Rebekah G. Langston, Mark R. Cookson, Aleksandra Beylina, Xylena Reed, Dorien Rosen

المصدر: Stem cell research
Stem Cell Research, Vol 53, Iss, Pp 102354-(2021)

مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, GTP', QH301-705.5, Leucine-rich repeat, Biology, Protein Serine-Threonine Kinases, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Article, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Leucine, medicine, Humans, Biology (General), Gene knockout, Genetics, Kinase, Parkinson Disease, Cell Biology, General Medicine, medicine.disease, LRRK2, Isogenic human disease models, nervous system diseases, 030104 developmental biology, Mutation, 030217 neurology & neurosurgery, Function (biology), Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a8cd4cb566dba17d50c29ccbfe8213
https://pubmed.ncbi.nlm.nih.gov/34087985

المؤلفون: A Beilina, Xylena Reed, Cornelis Blauwendraat, J. R. Gibbs, Rebekah G. Langston, Mark R. Cookson, AB Singleton

مصطلحات موضوعية: Genetics, Cell type, Parkinson's disease, Regulatory sequence, Genotype, medicine, Locus (genetics), Biology, Induced pluripotent stem cell, medicine.disease, Gene, LRRK2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d7d61777df4e81b0b2ed1c4e09eb3042
https://doi.org/10.1101/2021.01.15.426824

المؤلفون: Ramita Dewan, Mike A. Nalls, Sarah Ahmed, Sara Bandres-Ciga, Bryan J. Traynor, Ruth Chia, Yevgeniya Abramzon, Italsgen, Mina Ryten, Sara Saez-Atienzar, Mark R. Cookson, Regina H. Reynolds, John Landers, Shing Wan Choi, Jonggeol J. Kim, Rebekah G. Langston, Adriano Chiò

المصدر: Science Advances

مصطلحات موضوعية: Cell type, Disease, Biology, Polymorphism, Single Nucleotide, Genetic analysis, Biological pathway, 03 medical and health sciences, 0302 clinical medicine, Neuron projection morphogenesis, Mendelian randomization, Genetics, medicine, Humans, Genetic Testing, Amyotrophic lateral sclerosis, Research Articles, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Amyotrophic Lateral Sclerosis, SciAdv r-articles, medicine.disease, Signal transduction, Neuroscience, 030217 neurology & neurosurgery, Research Article, Genome-Wide Association Study

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f7e4411c414c94474cc22e54c75e82
https://doi.org/10.1126/sciadv.abd9036

المؤلفون: Analiz Rodriguez, Rebekah G. Langston, Ka Hin Wong, Edward H. Zhao

المصدر: American journal of surgery. 222(2)

مصطلحات موضوعية: Financing, Government, Biomedical Research, National Institutes of Health (U.S.), business.industry, General Surgery, Nih funding, Library science, Medicine, Humans, Surgery, General Medicine, business, United States

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4693059d3eb851b8cae094e36439447
https://pubmed.ncbi.nlm.nih.gov/33309253

المؤلفون: Manik C. Ghosh, Alexandra Beilina, Luis Bonet-Ponce, Rebekah G. Langston, Natalie Landeck, Adamantios Mamais, Alice Kaganovich, Ioannis Papazoglou, Jillian H. Kluss, Nunziata Maio, Changyoun Kim, Laura Pellegrini, Ravindran Kumaran, Mark R. Cookson, David C. Gershlick, Nathan Smith

مصطلحات موضوعية: chemistry.chemical_classification, Mutation, Microglia, biology, Endocytic cycle, medicine.disease_cause, LRRK2, nervous system diseases, Cell biology, Proinflammatory cytokine, Ferritin, medicine.anatomical_structure, chemistry, Transferrin, medicine, biology.protein, Kinase activity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::47cd9a49347fa5aacc111578b2b085fa
https://doi.org/10.1101/2020.07.27.219501

المؤلفون: Mina Ryten, Italsgen, Yevgeniya Abramzon, Sara Saez-Atienzar, Mark R. Cookson, Ramita Dewan, Mike A. Nalls, Sarah Ahmed, Rebekah G. Langston, Regina H. Reynolds, Adriano Chiò, Jonggeol J. Kim, Shing Wan Choi, Sara Bandres-Ciga, John Landers, Bryan J. Traynor, Ruth Chia

مصطلحات موضوعية: Biological pathway, Cell type, Neuron projection morphogenesis, Mendelian randomization, medicine, Disease, Signal transduction, Biology, Amyotrophic lateral sclerosis, medicine.disease, Neuroscience, Genetic analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e3c16030a87f567a6936184e2d3f1697
https://doi.org/10.1101/2020.07.20.211276

المؤلفون: Rebekah G, Langston, Mark R, Cookson

المصدر: Progress in brain research. 252

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Transcription, Genetic, Protein Biosynthesis, Proteolysis, Autophagy, alpha-Synuclein, Animals, Humans, Parkinson Disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::05b097dc855ac4cdb5c974c8d21705a9
https://pubmed.ncbi.nlm.nih.gov/32247365

المؤلفون: Adamantios Mamais (302600), Jillian H. Kluss (10333635), Luis Bonet-Ponce (336049), Natalie Landeck (414147), Rebekah G. Langston (5740400), Nathan Smith (341990), Alexandra Beilina (139251), Alice Kaganovich (347608), Manik C. Ghosh (11846063), Laura Pellegrini (694179), Ravindran Kumaran (4480765), Ioannis Papazoglou (11846066), George R. Heaton (11846069), Rina Bandopadhyay (302603), Nunziata Maio (11846072), Changyoun Kim (3479372), Matthew J. LaVoie (2287201), David C. Gershlick (11846075), Mark R. Cookson (139260)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Cancer, Biological Sciences not elsewhere classified, overexpression cell models, cellular responses downstream, modulating iron uptake, polymorphic lrrk2 variants, lrrk2 kinase substrate, common lrrk2 mutation, +mutations%22">xlink "> mutations, mediated iron uptake, lrrk2 induce sequestration, small gtpase rab8a, postmortem pd tissue, linked lrrk2 mutations, microglia , lrrk2 linked, iron deposition, mediated recycling, induce neurotoxicity, type mice, striatal accumulation, sporadic pd, significant increase, proinflammatory stimuli

Relation: https://figshare.com/articles/figure/Endogenous_MICAL-L1_is_recruited_by_mutant_LRRK2_to_lysosomes_/17221967

الاتاحة: https://doi.org/10.1371/journal.pbio.3001480.s004

المؤلفون: Adamantios Mamais (302600), Jillian H. Kluss (10333635), Luis Bonet-Ponce (336049), Natalie Landeck (414147), Rebekah G. Langston (5740400), Nathan Smith (341990), Alexandra Beilina (139251), Alice Kaganovich (347608), Manik C. Ghosh (11846063), Laura Pellegrini (694179), Ravindran Kumaran (4480765), Ioannis Papazoglou (11846066), George R. Heaton (11846069), Rina Bandopadhyay (302603), Nunziata Maio (11846072), Changyoun Kim (3479372), Matthew J. LaVoie (2287201), David C. Gershlick (11846075), Mark R. Cookson (139260)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Cancer, Biological Sciences not elsewhere classified, overexpression cell models, cellular responses downstream, modulating iron uptake, polymorphic lrrk2 variants, lrrk2 kinase substrate, common lrrk2 mutation, +mutations%22">xlink "> mutations, mediated iron uptake, lrrk2 induce sequestration, small gtpase rab8a, postmortem pd tissue, linked lrrk2 mutations, microglia , lrrk2 linked, iron deposition, mediated recycling, induce neurotoxicity, type mice, striatal accumulation, sporadic pd, significant increase, proinflammatory stimuli

Relation: https://figshare.com/articles/figure/Tf_recycling_in_iPSC-derived_microglia_/17221985

الاتاحة: https://doi.org/10.1371/journal.pbio.3001480.s007