المؤلفون: Paul A. Wilson (8867756), Sara Santos Franco (11592400), Liu He (246513), Nicholas W. Galwey (11592403), Jackie Meakin (11592406), Rebecca McIntyre (688872), Simon M. McHugh (11592409), Michael A. Nolan (11592412), Sarah L. Spain (11592415), Thaddeus Carlson (11592418), Mercedes Lobera (2232325), Justin P. Rubio (11592421), Bill Davis (525333), Linda C. McCarthy (4559770)

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, type 3 immunity, sup >+, several autoimmune diseases, profiles reported perturbation, inflammatory bowel disease, differential detoxification response, concept study indicated, cellular detoxification response, attractive therapeutic target, cell maintenance medium, cell differentiation events, wide association studies, metabolic signalling networks, may perturb immune, significant contributory role, div >< p, rorc inverse agonist, four culture conditions, driven transcriptional effects, associated rorc variant, ibd risk associated, cells , transcriptional effects

Relation: https://figshare.com/articles/journal_contribution/Supplementary_experimental_methods_/16848580

الاتاحة: https://doi.org/10.1371/journal.pone.0258316.s001

المؤلفون: Paul A. Wilson (8867756), Sara Santos Franco (11592400), Liu He (246513), Nicholas W. Galwey (11592403), Jackie Meakin (11592406), Rebecca McIntyre (688872), Simon M. McHugh (11592409), Michael A. Nolan (11592412), Sarah L. Spain (11592415), Thaddeus Carlson (11592418), Mercedes Lobera (2232325), Justin P. Rubio (11592421), Bill Davis (525333), Linda C. McCarthy (4559770)

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, type 3 immunity, sup >+, several autoimmune diseases, profiles reported perturbation, inflammatory bowel disease, differential detoxification response, concept study indicated, cellular detoxification response, attractive therapeutic target, cell maintenance medium, cell differentiation events, wide association studies, metabolic signalling networks, may perturb immune, significant contributory role, div >< p, rorc inverse agonist, four culture conditions, driven transcriptional effects, associated rorc variant, ibd risk associated, cells , transcriptional effects

Relation: https://figshare.com/articles/figure/Characterization_of_the_Th_cell_populations_by_flow_cytometry_at_day_6_of_cell_culture_under_each_of_the_four_growth_medium_formulations_T_cell_maintenance_medium_or_Th17_driving_medium_in_the_presence_of_either_GSK776_GSK2794776A_an_inacti/16848589

الاتاحة: https://doi.org/10.1371/journal.pone.0258316.g002

المؤلفون: Paul A. Wilson (8867756), Sara Santos Franco (11592400), Liu He (246513), Nicholas W. Galwey (11592403), Jackie Meakin (11592406), Rebecca McIntyre (688872), Simon M. McHugh (11592409), Michael A. Nolan (11592412), Sarah L. Spain (11592415), Thaddeus Carlson (11592418), Mercedes Lobera (2232325), Justin P. Rubio (11592421), Bill Davis (525333), Linda C. McCarthy (4559770)

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, type 3 immunity, sup >+, several autoimmune diseases, profiles reported perturbation, inflammatory bowel disease, differential detoxification response, concept study indicated, cellular detoxification response, attractive therapeutic target, cell maintenance medium, cell differentiation events, wide association studies, metabolic signalling networks, may perturb immune, significant contributory role, div >< p, rorc inverse agonist, four culture conditions, driven transcriptional effects, associated rorc variant, ibd risk associated, cells , transcriptional effects

Relation: https://figshare.com/articles/dataset/The_complete_statistical_summary_statistics_of_the_differential_expression_analysis_/16848583

الاتاحة: https://doi.org/10.1371/journal.pone.0258316.s002

المؤلفون: Paul A. Wilson (8867756), Sara Santos Franco (11592400), Liu He (246513), Nicholas W. Galwey (11592403), Jackie Meakin (11592406), Rebecca McIntyre (688872), Simon M. McHugh (11592409), Michael A. Nolan (11592412), Sarah L. Spain (11592415), Thaddeus Carlson (11592418), Mercedes Lobera (2232325), Justin P. Rubio (11592421), Bill Davis (525333), Linda C. McCarthy (4559770)

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, type 3 immunity, sup >+, several autoimmune diseases, profiles reported perturbation, inflammatory bowel disease, differential detoxification response, concept study indicated, cellular detoxification response, attractive therapeutic target, cell maintenance medium, cell differentiation events, wide association studies, metabolic signalling networks, may perturb immune, significant contributory role, div >< p, rorc inverse agonist, four culture conditions, driven transcriptional effects, associated rorc variant, ibd risk associated, cells , transcriptional effects

Relation: https://figshare.com/articles/figure/Flow_cytometric_analysis_of_CXCR3_versus_CCR6_of_live_CD4_sup_sup_cells_at_day_6_of_culture_was_used_to_characterize_the_Th1-like_and_Th17-like_cell_populations_/16848586

الاتاحة: https://doi.org/10.1371/journal.pone.0258316.g001

المؤلفون: Paul A. Wilson (8867756), Sara Santos Franco (11592400), Liu He (246513), Nicholas W. Galwey (11592403), Jackie Meakin (11592406), Rebecca McIntyre (688872), Simon M. McHugh (11592409), Michael A. Nolan (11592412), Sarah L. Spain (11592415), Thaddeus Carlson (11592418), Mercedes Lobera (2232325), Justin P. Rubio (11592421), Bill Davis (525333), Linda C. McCarthy (4559770)

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, type 3 immunity, sup >+, several autoimmune diseases, profiles reported perturbation, inflammatory bowel disease, differential detoxification response, concept study indicated, cellular detoxification response, attractive therapeutic target, cell maintenance medium, cell differentiation events, wide association studies, metabolic signalling networks, may perturb immune, significant contributory role, div >< p, rorc inverse agonist, four culture conditions, driven transcriptional effects, associated rorc variant, ibd risk associated, cells , transcriptional effects

Relation: https://figshare.com/articles/figure/Genotype_has_no_significant_effect_on_CD4_T_cell_proliferation_/16848592

الاتاحة: https://doi.org/10.1371/journal.pone.0258316.g003

المؤلفون: Paul A. Wilson (8867756), Sara Santos Franco (11592400), Liu He (246513), Nicholas W. Galwey (11592403), Jackie Meakin (11592406), Rebecca McIntyre (688872), Simon M. McHugh (11592409), Michael A. Nolan (11592412), Sarah L. Spain (11592415), Thaddeus Carlson (11592418), Mercedes Lobera (2232325), Justin P. Rubio (11592421), Bill Davis (525333), Linda C. McCarthy (4559770)

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, type 3 immunity, sup >+, several autoimmune diseases, profiles reported perturbation, inflammatory bowel disease, differential detoxification response, concept study indicated, cellular detoxification response, attractive therapeutic target, cell maintenance medium, cell differentiation events, wide association studies, metabolic signalling networks, may perturb immune, significant contributory role, div >< p, rorc inverse agonist, four culture conditions, driven transcriptional effects, associated rorc variant, ibd risk associated, cells , transcriptional effects

Relation: https://figshare.com/articles/figure/Transcriptional_profiles_cluster_according_to_choice_of_differentiation_medium_/16848595

الاتاحة: https://doi.org/10.1371/journal.pone.0258316.g004

المؤلفون: Paul A. Wilson (8867756), Sara Santos Franco (11592400), Liu He (246513), Nicholas W. Galwey (11592403), Jackie Meakin (11592406), Rebecca McIntyre (688872), Simon M. McHugh (11592409), Michael A. Nolan (11592412), Sarah L. Spain (11592415), Thaddeus Carlson (11592418), Mercedes Lobera (2232325), Justin P. Rubio (11592421), Bill Davis (525333), Linda C. McCarthy (4559770)

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, type 3 immunity, sup >+, several autoimmune diseases, profiles reported perturbation, inflammatory bowel disease, differential detoxification response, concept study indicated, cellular detoxification response, attractive therapeutic target, cell maintenance medium, cell differentiation events, wide association studies, metabolic signalling networks, may perturb immune, significant contributory role, div >< p, rorc inverse agonist, four culture conditions, driven transcriptional effects, associated rorc variant, ibd risk associated, cells , transcriptional effects

Relation: https://figshare.com/articles/figure/RORC_transcripts_are_differentially_expressed_in_presence_of_differentiating_medium_/16848598

الاتاحة: https://doi.org/10.1371/journal.pone.0258316.g005

المؤلفون: Paul A. Wilson (8867756), Sara Santos Franco (11592400), Liu He (246513), Nicholas W. Galwey (11592403), Jackie Meakin (11592406), Rebecca McIntyre (688872), Simon M. McHugh (11592409), Michael A. Nolan (11592412), Sarah L. Spain (11592415), Thaddeus Carlson (11592418), Mercedes Lobera (2232325), Justin P. Rubio (11592421), Bill Davis (525333), Linda C. McCarthy (4559770)

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, type 3 immunity, sup >+, several autoimmune diseases, profiles reported perturbation, inflammatory bowel disease, differential detoxification response, concept study indicated, cellular detoxification response, attractive therapeutic target, cell maintenance medium, cell differentiation events, wide association studies, metabolic signalling networks, may perturb immune, significant contributory role, div >< p, rorc inverse agonist, four culture conditions, driven transcriptional effects, associated rorc variant, ibd risk associated, cells , transcriptional effects

Relation: https://figshare.com/articles/figure/Genotype_is_associated_with_differential_transcriptional_effects_on_effects_on_canonical_immune_and_metabolic_signalling_networks_/16848601

الاتاحة: https://doi.org/10.1371/journal.pone.0258316.g006

المؤلفون: Paul A. Wilson (8867756), Sara Santos Franco (11592400), Liu He (246513), Nicholas W. Galwey (11592403), Jackie Meakin (11592406), Rebecca McIntyre (688872), Simon M. McHugh (11592409), Michael A. Nolan (11592412), Sarah L. Spain (11592415), Thaddeus Carlson (11592418), Mercedes Lobera (2232325), Justin P. Rubio (11592421), Bill Davis (525333), Linda C. McCarthy (4559770)

مصطلحات موضوعية: Cell Biology, Genetics, Molecular Biology, Neuroscience, Immunology, Developmental Biology, Biological Sciences not elsewhere classified, type 3 immunity, sup >+, several autoimmune diseases, profiles reported perturbation, inflammatory bowel disease, differential detoxification response, concept study indicated, cellular detoxification response, attractive therapeutic target, cell maintenance medium, cell differentiation events, wide association studies, metabolic signalling networks, may perturb immune, significant contributory role, div >< p, rorc inverse agonist, four culture conditions, driven transcriptional effects, associated rorc variant, ibd risk associated, cells , transcriptional effects

Relation: https://figshare.com/articles/figure/The_homozygous_genotype_differentially_effects_transcriptional_response_in_the_presence_of_an_RORC_inverse_agonist_/16848604

الاتاحة: https://doi.org/10.1371/journal.pone.0258316.g007