المؤلفون: Walsh, Samuel McEwen, Mathiasen, Signe, Christensen, Sune M., Fay, Jonathan F., King, Christopher, Provasi, Davide, Borrero, Ernesto, Rasmussen, Søren Gøgsig Faarup, Fung, Juan Jose, Filizola, Marta, Hristova, Kalina, Kobilka, Brian, Farrens, David L., Stamou, Dimitrios

المصدر: Walsh , S M , Mathiasen , S , Christensen , S M , Fay , J F , King , C , Provasi , D , Borrero , E , Rasmussen , S G F , Fung , J J , Filizola , M , Hristova , K , Kobilka , B , Farrens , D L & Stamou , D 2018 , ' Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs ' , Biophysical Journal , vol. 115 , no. 2 , pp. 300-312 . https://doi.org/10.1016/j.bpj.2018.05.036

الاتاحة: https://researchprofiles.ku.dk/da/publications/single-proteoliposome-highcontent-analysis-reveals-differences-in-the-homooligomerization-of-gpcrs(c0ebe0c3-6cad-4f18-b668-ddcdf4664063).html
https://doi.org/10.1016/j.bpj.2018.05.036
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050755/pdf/main.pdf

المؤلفون: Kuszak, A. J., Yao, Xiao Jie, Rasmussen, Søren Gøgsig Faarup, Kobilka, Brian, Sunahara, Roger K

المصدر: Kuszak , A J , Yao , X J , Rasmussen , S G F , Kobilka , B & Sunahara , R K 2010 , Functional studies of isolated GPCR-G protein complexes in the membrane bilayer of lipoprotein particles . in G Protein-Coupled Receptors . Cambridge University Press , pp. 32-52 .

الاتاحة: https://researchprofiles.ku.dk/da/publications/functional-studies-of-isolated-gpcrg-protein-complexes-in-the-membrane-bilayer-of-lipoprotein-particles(21e26c55-f234-4546-b8ea-1fd33efde1e1).html

المؤلفون: Rosenbaum, Daniel, Rasmussen, Søren Gøgsig Faarup, Kobilka, Brian

المصدر: Rosenbaum , D , Rasmussen , S G F & Kobilka , B 2009 , The beta2 Adrenergic Receptor as a Model for G Protein-Coupled Receptor Structure and Activation by Diffusible Hormones . in Handbook of Cell Signaling . Elsevier Editora .

الاتاحة: https://curis.ku.dk/portal/da/publications/the-beta2-adrenergic-receptor-as-a-model-for-g-proteincoupled-receptor-structure-and-activation-by-diffusible-hormones(43493e7f-e1df-43d7-9e84-e76aa69a4b24).html

المؤلفون: Weis, William I., Rosenbaum, Daniel, Rasmussen, Søren Gøgsig Faarup

المصدر: Weis , W I , Rosenbaum , D , Rasmussen , S G F & et. al , E A 2009 , Crystal Structures of the ß2-Adrenergic Receptor . in From Molecules to Medicines, Structure of Biological Macromolecules and Its Relevance in Combating New Diseases and Bioterrorism . Springer , pp. 217-230 .

الاتاحة: https://curis.ku.dk/portal/da/publications/crystal-structures-of-the-ss2adrenergic-receptor(03d2f326-d090-4ce9-a143-eced00b64522).html

المؤلفون: Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik

المصدر: Rasmussen , S G F & Gether , U 2006 , Molecular mechanisms of GPCR activation . in G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive ActivityG Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity . vol. 24 , Wiley , 2006 , pp. 27-42 .

الاتاحة: https://curis.ku.dk/portal/da/publications/molecular-mechanisms-of-gpcr-activation(dda8067b-7e37-4ccd-a899-94213dd57e9c).html

المؤلفون: Pardon, Els, Laeremans, Toon, Triest, Sarah, Rasmussen, Søren Gøgsig Faarup, Wohlkönig, Alexandre, Ruf, Armin, Muyldermans, Serge, Hol, Wim G J, Kobilka, Brian K, Steyaert, Jan

المصدر: Pardon , E , Laeremans , T , Triest , S , Rasmussen , S G F , Wohlkönig , A , Ruf , A , Muyldermans , S , Hol , W G J , Kobilka , B K & Steyaert , J 2014 , ' A general protocol for the generation of Nanobodies for structural biology ' , Nature Protocols (Print) , vol. 9 , no. 3 , pp. 674-93 . https://doi.org/10.1038/nprot.2014.039

الاتاحة: https://researchprofiles.ku.dk/da/publications/a-general-protocol-for-the-generation-of-nanobodies-for-structural-biology(cf2c082c-bdea-47bc-a774-89dc0b49e16e).html
https://doi.org/10.1038/nprot.2014.039

المؤلفون: Staus, Dean P, Wingler, Laura M, Strachan, Ryan T, Rasmussen, Søren Gøgsig Faarup, Pardon, Els, Ahn, Seungkirl, Steyaert, Jan, Kobilka, Brian K, Lefkowitz, Robert J

المصدر: Staus , D P , Wingler , L M , Strachan , R T , Rasmussen , S G F , Pardon , E , Ahn , S , Steyaert , J , Kobilka , B K & Lefkowitz , R J 2014 , ' Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies ' , Molecular Pharmacology , vol. 85 , no. 3 , pp. 472-81 . https://doi.org/10.1124/mol.113.089516

مصطلحات موضوعية: Amino Acid Sequence, Cell Line, Cyclic AMP, G-Protein-Coupled Receptor Kinases, HEK293 Cells, Humans, Molecular Sequence Data, Phosphorylation, Protein Binding, Receptors, Adrenergic, beta-2, G-Protein-Coupled, Sequence Alignment, Single-Domain Antibodies

الاتاحة: https://curis.ku.dk/portal/da/publications/regulation-of-2adrenergic-receptor-function-by-conformationally-selective-singledomain-intrabodies(4b7a2643-6e5b-4c17-974f-f10ea684bc96).html
https://doi.org/10.1124/mol.113.089516

المؤلفون: Mathiasen, Signe, Christensen, Sune M., Fung, Juan José, Rasmussen, Søren Gøgsig Faarup, Fay, Jonathan F., Jørgensen, Sune Klamer, Veshaguri, Salome, Farrens, David L., Kiskowski, Maria, Kobilka, Brian, Stamou, Dimitrios

المصدر: Mathiasen , S , Christensen , S M , Fung , J J , Rasmussen , S G F , Fay , J F , Jørgensen , S K , Veshaguri , S , Farrens , D L , Kiskowski , M , Kobilka , B & Stamou , D 2014 , ' Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes ' , Nature Methods , vol. 11 , pp. 931-934 . https://doi.org/10.1038/nmeth.3062

الاتاحة: https://researchprofiles.ku.dk/da/publications/nanoscale-highcontent-analysis-using-compositional-heterogeneities-of-single-proteoliposomes(86dfae16-bb3b-44f5-a260-c0b2ec8c4855).html
https://doi.org/10.1038/nmeth.3062

المؤلفون: Irannejad, R, Tomshine, Jin C, Tomshine, Jon R, Chevalier, Michael, Mahoney, Jacob P, Steyaert, Jan, Rasmussen, Søren Gøgsig Faarup, Sunahara, Roger K, El-Samad, Hana, Huang, Bo, von Zastrow, Mark

المصدر: Irannejad , R , Tomshine , J C , Tomshine , J R , Chevalier , M , Mahoney , J P , Steyaert , J , Rasmussen , S G F , Sunahara , R K , El-Samad , H , Huang , B & von Zastrow , M 2013 , ' Conformational biosensors reveal GPCR signalling from endosomes ' , Nature , vol. 495 , no. 7442 , pp. 534-8 . https://doi.org/10.1038/nature12000

الاتاحة: https://researchprofiles.ku.dk/da/publications/conformational-biosensors-reveal-gpcr-signalling-from-endosomes(e7e25b39-9c27-4c4d-83c7-62fe7998e083).html
https://doi.org/10.1038/nature12000

المؤلفون: Rasmussen, Søren Gøgsig Faarup, DeVree, Brian T, Zou, Yaozhong, Kruse, Andrew C, Chung, Ka Young, Kobilka, Tong Sun, Thian, Foon Sun, Chae, Pil Seok, Pardon, Els, Calinski, Diane, Mathiesen, Jesper M, Shah, Syed T A, Lyons, Joseph A, Caffrey, Martin, Gellman, Samuel H, Steyaert, Jan, Skiniotis, Georgios, Weis, William I, Sunahara, Roger K, Kobilka, Brian K

المصدر: Rasmussen , S G F , DeVree , B T , Zou , Y , Kruse , A C , Chung , K Y , Kobilka , T S , Thian , F S , Chae , P S , Pardon , E , Calinski , D , Mathiesen , J M , Shah , S T A , Lyons , J A , Caffrey , M , Gellman , S H , Steyaert , J , Skiniotis , G , Weis , W I , Sunahara , R K & Kobilka , B K 2011 , ' Crystal ....

مصطلحات موضوعية: Adrenergic beta-2 Receptor Agonists, Animals, Catalytic Domain, Cattle, Crystallization, Crystallography, X-Ray, Enzyme Activation, GTP-Binding Protein alpha Subunits, Gs, Models, Molecular, Multiprotein Complexes, Protein Binding, Rats, Receptors, Adrenergic, beta-2

الاتاحة: https://researchprofiles.ku.dk/da/publications/crystal-structure-of-the-2-adrenergic-receptorgs-protein-complex(a9268340-3d2b-416d-833c-98333a4014e1).html
https://doi.org/10.1038/nature10361

المؤلفون: Rosenbaum, Daniel M, Zhang, Cheng, Lyons, Joseph A, Holl, Ralph, Aragao, David, Arlow, Daniel H, Rasmussen, Søren Gøgsig Faarup, Choi, Hee-Jung, Devree, Brian T, Sunahara, Roger K, Chae, Pil Seok, Gellman, Samuel H, Dror, Ron O, Shaw, David E, Weis, William I, Caffrey, Martin, Gmeiner, Peter, Kobilka, Brian K

المصدر: Rosenbaum , D M , Zhang , C , Lyons , J A , Holl , R , Aragao , D , Arlow , D H , Rasmussen , S G F , Choi , H-J , Devree , B T , Sunahara , R K , Chae , P S , Gellman , S H , Dror , R O , Shaw , D E , Weis , W I , Caffrey , M , Gmeiner , P & Kobilka , B K 2011 , ' Structure and function of an irreversible agonist-β(2) adrenoceptor complex ' , Nature ....

مصطلحات موضوعية: Adrenergic beta-2 Receptor Agonists, Crystallization, Crystallography, X-Ray, Disulfides, Drug Inverse Agonism, Heterotrimeric GTP-Binding Proteins, Humans, Lipid Bilayers, Models, Molecular, Molecular Dynamics Simulation, Procaterol, Propanolamines, Protein Conformation, Receptors, Adrenergic, beta-2, Recombinant Fusion Proteins, Viral Proteins

الاتاحة: https://researchprofiles.ku.dk/da/publications/structure-and-function-of-an-irreversible-agonist2-adrenoceptor-complex(53d5e6a9-6bd9-4aca-89b3-e06420487fc2).html
https://doi.org/10.1038/nature09665

المؤلفون: Rasmussen, Søren Gøgsig Faarup, Choi, Hee-Jung, Fung, Juan Jose, Pardon, Els, Casarosa, Paola, Chae, Pil Seok, Devree, Brian T, Rosenbaum, Daniel M, Thian, Foon Sun, Kobilka, Tong Sun, Schnapp, Andreas, Konetzki, Ingo, Sunahara, Roger K, Gellman, Samuel H, Pautsch, Alexander, Steyaert, Jan, Weis, William I, Kobilka, Brian K

المصدر: Rasmussen , S G F , Choi , H-J , Fung , J J , Pardon , E , Casarosa , P , Chae , P S , Devree , B T , Rosenbaum , D M , Thian , F S , Kobilka , T S , Schnapp , A , Konetzki , I , Sunahara , R K , Gellman , S H , Pautsch , A , Steyaert , J , Weis , W I & Kobilka , B K 2011 , ' Structure of a nanobody-stabilized active state of the β(2) adrenoceptor ' , Nature ....

مصطلحات موضوعية: Adrenergic beta-2 Receptor Agonists, Animals, Binding Sites, Camelids, New World, Crystallography, X-Ray, Drug Inverse Agonism, Humans, Immunoglobulin Fragments, Ligands, Models, Molecular, Movement, Nanostructures, Opsins, Propanolamines, Protein Conformation, Protein Stability, Receptors, Adrenergic, beta-2, Viral Proteins

الاتاحة: https://researchprofiles.ku.dk/da/publications/structure-of-a-nanobodystabilized-active-state-of-the-2-adrenoceptor(19f666fd-86b4-4b2d-a53a-957e2f136c5e).html
https://doi.org/10.1038/nature09648

المؤلفون: Selao, Tiago Toscano, Branca, Rui, Chae, Pil Seok, Lehtiö, Janne, Gellman, Samuel H, Rasmussen, Søren Gøgsig Faarup, Nordlund, Stefan, Norén, Agneta

المصدر: Selao , T T , Branca , R , Chae , P S , Lehtiö , J , Gellman , S H , Rasmussen , S G F , Nordlund , S & Norén , A 2011 , ' Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum ' , Journal of Proteome Research , vol. 10 , no. 6 , pp. 2703-14 . https://doi.org/10.1021/pr100838x

مصطلحات موضوعية: ATP Synthetase Complexes, Ammonium Chloride, Bacterial Chromatophores, Citric Acid Cycle, Electron Transport Complex I, Electrophoresis, Gel, Two-Dimensional, Flavoproteins, Light-Harvesting Protein Complexes, Membrane Proteins, Membrane Transport Proteins, Nitrogen, Nitrogen Fixation, Rhodospirillum rubrum, Subcellular Fractions

الاتاحة: https://curis.ku.dk/portal/da/publications/identification-of-chromatophore-membrane-protein-complexes-formed-under-different-nitrogen-availability-conditions-in-rhodospirillum-rubrum(2d97df5d-2c4d-42ff-9eda-d167c9ad89de).html
https://doi.org/10.1021/pr100838x

المؤلفون: Chung, Ka Young, Rasmussen, Søren Gøgsig Faarup, Liu, Tong, Li, Sheng, DeVree, Brian T, Chae, Pil Seok, Calinski, Diane, Kobilka, Brian K, Woods, Virgil L, Sunahara, Roger K

المصدر: Chung , K Y , Rasmussen , S G F , Liu , T , Li , S , DeVree , B T , Chae , P S , Calinski , D , Kobilka , B K , Woods , V L & Sunahara , R K 2011 , ' Conformational changes in the G protein Gs induced by the β2 adrenergic receptor ' , Nature , vol. 477 , no. 7366 , pp. 611-5 . https://doi.org/10.1038/nature10488

مصطلحات موضوعية: Adrenergic beta-2 Receptor Agonists, Animals, Biocatalysis, Catalytic Domain, Cattle, Crystallography, X-Ray, Deuterium Exchange Measurement, GTP-Binding Protein alpha Subunits, Gs, Guanosine Diphosphate, Guanosine Triphosphate, Humans, Models, Molecular, Protein Binding, Protein Conformation, Receptors, Adrenergic, beta-2

الاتاحة: https://researchprofiles.ku.dk/da/publications/conformational-changes-in-the-g-protein-gs-induced-by-the-2-adrenergic-receptor(63122bad-2071-4549-9f48-8ef6686bb22a).html
https://doi.org/10.1038/nature10488

المؤلفون: Westfield, Gerwin H, Rasmussen, Søren Gøgsig Faarup, Su, Min, Dutta, Somnath, DeVree, Brian T, Chung, Ka Young, Calinski, Diane, Velez-Ruiz, Gisselle, Oleskie, Austin N, Pardon, Els, Chae, Pil Seok, Liu, Tong, Li, Sheng, Woods, Virgil L, Steyaert, Jan, Kobilka, Brian K, Sunahara, Roger K, Skiniotis, Georgios

المصدر: Westfield , G H , Rasmussen , S G F , Su , M , Dutta , S , DeVree , B T , Chung , K Y , Calinski , D , Velez-Ruiz , G , Oleskie , A N , Pardon , E , Chae , P S , Liu , T , Li , S , Woods , V L , Steyaert , J , Kobilka , B K , Sunahara , R K & Skiniotis , G 2011 , ' Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex ' ....

مصطلحات موضوعية: Animals, Crystallization, Crystallography, X-Ray, GTP-Binding Protein alpha Subunits, Gs, Guanosine 5'-O-(3-Thiotriphosphate), Guanosine Diphosphate, Guanosine Triphosphate, Microscopy, Electron, Models, Molecular, Protein Binding, Protein Conformation, Protein Structure, Secondary, Tertiary, Receptors, Adrenergic, beta-2

الاتاحة: https://researchprofiles.ku.dk/da/publications/structural-flexibility-of-the-g-alpha-s-alphahelical-domain-in-the-beta2adrenoceptor-gs-complex(7dcb96c9-09cb-4183-ada7-c376663d790a).html
https://doi.org/10.1073/pnas.1113645108

المؤلفون: Bokoch, Michael P, Zou, Yaozhong, Rasmussen, Søren Gøgsig Faarup, Liu, Corey W, Nygaard, Rie, Rosenbaum, Daniel M, Fung, Juan José, Choi, Hee-Jung, Thian, Foon Sun, Kobilka, Tong Sun, Puglisi, Joseph D, Weis, William I, Pardo, Leonardo, Prosser, R Scott, Mueller, Luciano, Kobilka, Brian K

المصدر: Bokoch , M P , Zou , Y , Rasmussen , S G F , Liu , C W , Nygaard , R , Rosenbaum , D M , Fung , J J , Choi , H-J , Thian , F S , Kobilka , T S , Puglisi , J D , Weis , W I , Pardo , L , Prosser , R S , Mueller , L & Kobilka , B K 2010 , ' Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor ' , Nature , vol. 463 , no. 7277 , pp. ....

مصطلحات موضوعية: Adrenergic beta-2 Receptor Agonists, Adrenergic beta-2 Receptor Antagonists, Allosteric Regulation, Binding Sites, Crystallography, X-Ray, Drug Inverse Agonism, Ethanolamines, Humans, Ligands, Lysine, Methylation, Models, Molecular, Mutant Proteins, Nuclear Magnetic Resonance, Biomolecular, Propanolamines, Protein Structure, Tertiary, Receptors, Adrenergic, beta-2, Static Electricity, Substrate Specificity

الاتاحة: https://researchprofiles.ku.dk/da/publications/ligandspecific-regulation-of-the-extracellular-surface-of-a-gproteincoupled-receptor(27fe5b89-ec39-478f-aa6f-a4b357ee8a50).html
https://doi.org/10.1038/nature08650

المؤلفون: Yao, Xiao Jie, Vélez Ruiz, Gisselle, Whorton, Matthew R, Rasmussen, Søren Gøgsig Faarup, DeVree, Brian T, Deupi, Xavier, Sunahara, Roger K, Kobilka, Brian

المصدر: Yao , X J , Vélez Ruiz , G , Whorton , M R , Rasmussen , S G F , DeVree , B T , Deupi , X , Sunahara , R K & Kobilka , B 2009 , ' The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 106 , no. 23 , pp. 9501-6 . https://doi.org/10.1073/pnas.0811437106

مصطلحات موضوعية: Adrenergic beta-2 Receptor Antagonists, Bicyclo Compounds, GTP-Binding Proteins, Humans, Ligands, Protein Stability, Receptors, Adrenergic, beta-2, Signal Transduction

الاتاحة: https://curis.ku.dk/portal/da/publications/the-effect-of-ligand-efficacy-on-the-formation-and-stability-of-a-gpcrg-protein-complex(602288c0-9564-4fc8-a28f-9f1981943efb).html
https://doi.org/10.1073/pnas.0811437106

المؤلفون: Rosenbaum, Daniel M, Rasmussen, Søren Gøgsig Faarup, Kobilka, Brian K

المصدر: Rosenbaum , D M , Rasmussen , S G F & Kobilka , B K 2009 , ' The structure and function of G-protein-coupled receptors ' , Nature , vol. 459 , no. 7245 , pp. 356-63 . https://doi.org/10.1038/nature08144

مصطلحات موضوعية: Animals, Conserved Sequence, Cytoplasm, Humans, Opsins, Protein Conformation, Receptors, G-Protein-Coupled, Signal Transduction

الاتاحة: https://researchprofiles.ku.dk/da/publications/the-structure-and-function-of-gproteincoupled-receptors(5e207d42-324b-464f-85f4-e28891bdce0d).html
https://doi.org/10.1038/nature08144

المؤلفون: Richter, Wito, Day, Peter, Agrawal, Rani, Bruss, Matthew D, Granier, Sébastien, Wang, Yvonne L, Rasmussen, Søren Gøgsig Faarup, Horner, Kathleen, Wang, Ping, Lei, Tao, Patterson, Andrew J, Kobilka, Brian, Conti, Marco

المصدر: Richter , W , Day , P , Agrawal , R , Bruss , M D , Granier , S , Wang , Y L , Rasmussen , S G F , Horner , K , Wang , P , Lei , T , Patterson , A J , Kobilka , B & Conti , M 2008 , ' Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4 ' , E M B O Journal , vol. 27 , no. 2 , pp. 384-93 . https://doi.org/10.1038/sj.emboj.7601968

مصطلحات موضوعية: Animals, Newborn, Cell Line, Cells, Cultured, Cyclic AMP, Cyclic Nucleotide Phosphodiesterases, Type 4, Humans, Immunoprecipitation, Mice, Models, Biological, Muscle Cells, Promoter Regions, Genetic, Protein Binding, Protein Isoforms, Receptors, Adrenergic, beta-1, beta-2, Signal Transduction

الاتاحة: https://researchprofiles.ku.dk/da/publications/signaling-from-beta1-and-beta2adrenergic-receptors-is-defined-by-differential-interactions-with-pde4(2adee0aa-c6f7-45cf-a2e2-66007491ba8c).html
https://doi.org/10.1038/sj.emboj.7601968

المؤلفون: Day, Peter W, Rasmussen, Søren Gøgsig Faarup, Parnot, Charles, Fung, Juan José, Masood, Asna, Kobilka, Tong Sun, Yao, Xiao-Jie, Choi, Hee-Jung, Weis, William I, Rohrer, Daniel K, Kobilka, Brian K

المصدر: Day , P W , Rasmussen , S G F , Parnot , C , Fung , J J , Masood , A , Kobilka , T S , Yao , X-J , Choi , H-J , Weis , W I , Rohrer , D K & Kobilka , B K 2007 , ' A monoclonal antibody for G protein-coupled receptor crystallography ' , Nature Methods , vol. 4 , no. 11 , pp. 927-9 . https://doi.org/10.1038/nmeth1112

مصطلحات موضوعية: Amino Acid Sequence, Animals, Antibodies, Monoclonal, Antigen-Antibody Reactions, Blotting, Western, Crystallization, Crystallography, Epitopes, Fluorescent Dyes, Humans, Immunoglobulin Fab Fragments, Mice, Molecular Sequence Data, Protein Structure, Tertiary, Receptors, Adrenergic, beta-2, G-Protein-Coupled, Recombinant Proteins, Rhodamines, Vaccination

الاتاحة: https://researchprofiles.ku.dk/da/publications/a-monoclonal-antibody-for-g-proteincoupled-receptor-crystallography(3046f264-75f4-463a-b0b8-1a2d394cefcc).html
https://doi.org/10.1038/nmeth1112