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1
المؤلفون: Charu Chaudhry, Ping Zhang, Kyoung S. Kim, William J. Pitts, Cornelius Lyndon A M, Lynn M. Abell, Hart Amy C, Kevin O’Malley, Junqing Guo, Brian Carpenter, Hao Lu, Ramesh Padmanabha, Patrick J. Shaw, Mertzman Michael E, Kevin Kish, Andrew E Douglas, Matthew Pokross, John E. Macor, Deepa Calambur, Carolyn A. Weigelt
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: 010405 organic chemistry, Kinase, Chemistry, Necroptosis, Organic Chemistry, Computational biology, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Drug Discovery, Transferase, Identification (biology), Signal transduction
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2Academic Journal
المؤلفون: Jeremy H. Toyn, Lorin A. Thompson, Kimberley A. Lentz, Jere E. Meredith, Catherine R. Burton, Sethu Sankaranararyanan, Valerie Guss, Tracey Hall, Lawrence G. Iben, Carol M. Krause, Rudy Krause, Xu-Alan Lin, Maria Pierdomenico, Craig Polson, Alan S. Robertson, R. Rex Denton, James E. Grace, John Morrison, Joseph Raybon, Xiaoliang Zhuo, Kimberly Snow, Ramesh Padmanabha, Michele Agler, Kim Esposito, David Harden, Margaret Prack, Sam Varma, Victoria Wong, Yingjie Zhu, Tatyana Zvyaga, Samuel Gerritz, Lawrence R. Marcin, Mendi A. Higgins, Jianliang Shi, Cong Wei, Joseph L. Cantone, Dieter M. Drexler, John E. Macor, Richard E. Olson, Michael K. Ahlijanian, Charles F. Albright
المصدر: International Journal of Alzheimer's Disease, Vol 2014 (2014)
مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Geriatrics, RC952-954.6
Relation: http://dx.doi.org/10.1155/2014/431858; https://doaj.org/toc/2090-8024; https://doaj.org/toc/2090-0252; https://doaj.org/article/1dce320132d4411583a19dcbfe2b54ae
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3
المؤلفون: John Morrison, Kenneth M. Boy, Alan S. Robertson, Malaz AbuTarif, Jeremy H. Toyn, Valerie Guss, Xiaoliang Zhuo, Maciej Gasior, James E. Grace, Cong Wei, Jun-Sheng Wang, Quan Hong, Joseph Raybon, Lynda S. Cook, Nina Hoque, Richard E. Olson, Wendy Clarke, Rex Denton, Lorin A. Thompson, Francis Sweeney, Flora Berisha, Jere E. Meredith, Dieter M. Drexler, Holly Soares, Kimberly A. Lentz, Charlie F. Albright, Ramesh Padmanabha, Michael J. Furlong, John E. Macor, Michael K. Ahlijanian, Dmitry Zuev, Kimberly Snow
المصدر: The Journal of Pharmacology and Experimental Therapeutics
مصطلحات موضوعية: Bridged-Ring Compounds, 0301 basic medicine, Drug Evaluation, Preclinical, Peptide, Pharmacology, Cell Line, Rats, Sprague-Dawley, Drug Discovery and Translational Medicine, 03 medical and health sciences, Dogs, 0302 clinical medicine, Species Specificity, Pharmacokinetics, In vivo, Animals, Humans, Tissue Distribution, chemistry.chemical_classification, Amyloid beta-Peptides, Aniline Compounds, Dose-Response Relationship, Drug, Receptors, Notch, biology, Brain, Translation (biology), Biological activity, Small molecule, In vitro, Macaca fascicularis, Pyrimidines, 030104 developmental biology, chemistry, biology.protein, Molecular Medicine, Female, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase, 030217 neurology & neurosurgery
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4
المؤلفون: John E. Macor, Ramesh Padmanabha, Jere E. Meredith, Jeremy H. Toyn, William J. Metzler, Andrew J. Tebben, Jodi K. Muckelbauer, Charles F. Albright, Lynda S. Cook, Lorin A. Thompson, Samuel Gerritz, Michael J. Sofia, Michael A. Poss, Shirong Zhu, Lawrence G. Iben, Daniel M. Camac, Kimberley A. Lentz, Shuhao Shi, Andrew C. Good, Weixu Zhai, Catherine R. Burton
المصدر: Journal of Medicinal Chemistry. 55:9208-9223
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Substituent, Plasma protein binding, Crystallography, X-Ray, Guanidines, Cell Line, Small Molecule Libraries, Amyloid beta-Protein Precursor, Radioligand Assay, Structure-Activity Relationship, chemistry.chemical_compound, Amide, Drug Discovery, Animals, Aspartic Acid Endopeptidases, Humans, Structure–activity relationship, Guanidine, Solid-Phase Synthesis Techniques, Isothiazole, Amyloid beta-Peptides, Molecular Structure, Brain, Isoxazoles, Ligand (biochemistry), Peptide Fragments, Rats, Solutions, chemistry, Mutation, Molecular Medicine, Amyloid Precursor Protein Secretases, Protein Binding
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5
المؤلفون: Bang-Chi Chen, Neil Flynn, R. Michael Lawrence, Rulin Zhao, Ching-Hsuen Chu, James J. Li, Vito G. Sasseville, Scott A. Biller, Luping Chen, Randy Ponticiello, Haixia Wang, Dora M. Schnur, Dong Cheng, Jamil Haris, Jeffrey A. Robl, Kristen Pike, Joseph A. Tino, Mary T. Obermeier, Thomas Harrity, Timothy F. Herpin, Ramesh Padmanabha
المصدر: Bioorganic & Medicinal Chemistry Letters. 17:3208-3211
مصطلحات موضوعية: Blood Glucose, ATP citrate lyase, Clinical Biochemistry, Pharmaceutical Science, ATP Citrate (pro-S)-Lyase, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Structure–activity relationship, Enzyme Inhibitors, Molecular Biology, Cells, Cultured, Triglycerides, chemistry.chemical_classification, Sulfonamides, biology, Triglyceride, Cholesterol, Body Weight, Organic Chemistry, Benzene, Lyase, Rats, Enzyme, Adipose Tissue, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Anti-Obesity Agents
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6
المؤلفون: James Gill, Ramesh Padmanabha, Lynda S. Cook
المصدر: Combinatorial Chemistry & High Throughput Screening. 8:521-527
مصطلحات موضوعية: Quality Control, Process (engineering), Computer science, business.industry, media_common.quotation_subject, Organic Chemistry, Control (management), Emphasis (telecommunications), Information Storage and Retrieval, Compound management, General Medicine, Automation, Computer Science Applications, Reliability engineering, Pharmaceutical Preparations, Informatics, Drug Discovery, Quality (business), business, Throughput (business), media_common
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7
المؤلفون: Henry Wong, John J. Herbst, Kin Sing Lam, Kim Esposito, Shuhao Shi, Samuel Gerritz, Yue Zhong Shu, Michael J. Sofia, Wenying Li, Ramesh Padmanabha, Shirong Zhu
المصدر: Bioorganic & Medicinal Chemistry Letters. 15:4151-4154
مصطلحات موضوعية: Staphylococcus aureus, Clinical Biochemistry, Pharmaceutical Science, medicine.disease_cause, Biochemistry, Chemical synthesis, Cell Line, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, Solid-phase synthesis, Anti-Infective Agents, Drug Discovery, medicine, Combinatorial Chemistry Techniques, Humans, Candida albicans, Molecular Biology, Anisomycin, Antibacterial agent, Biological Products, Natural product, Molecular Structure, biology, Organic Chemistry, Fungi, Biological activity, biology.organism_classification, chemistry, Molecular Medicine
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8
المؤلفون: Lynda S. Cook, Laura Zawadzke, Ramesh Padmanabha, Ping Wu, Margaret Casperson, Li Fan, Mona Kishnani, Deepa Calambur, Hofstead Sandra J
المصدر: Analytical Biochemistry. 314:243-252
مصطلحات موضوعية: Time Factors, Biophysics, Transferases (Other Substituted Phosphate Groups), Bacterial enzymes, Biology, N-Acetylglucosaminyltransferases, medicine.disease_cause, Biochemistry, Inhibitory Concentration 50, Bacterial Proteins, Cell Wall, Transferases, Escherichia coli, medicine, Inhibitory concentration 50, Plate assay, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Escherichia coli Proteins, Nucleosides, Cell Biology, Antimicrobial, Molecular biology, Anti-Bacterial Agents, Molecular Weight, Enzyme, chemistry, Electrophoresis, Polyacrylamide Gel, Membrane fraction, MurG enzyme, Bacterial Outer Membrane Proteins
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9
المؤلفون: Lynda S. Cook, Susan P. Manly, Marcella Donovan, Susan E. Lowe, Yue-Zhong Shu, Ramesh Padmanabha, Judith A. Veitch, Dolores M. Pirnik, Stella Huang
المصدر: Bioorganic & Medicinal Chemistry Letters. 8:569-574
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, chemistry.chemical_compound, Drug Discovery, Agroclavine, Enzyme Inhibitors, Ergolines, Molecular Biology, chemistry.chemical_classification, biology, Organic Chemistry, Penicillium, Stereoisomerism, Biological activity, biology.organism_classification, In vitro, Enzyme, Models, Chemical, chemistry, Lymphocyte Specific Protein Tyrosine Kinase p56(lck), Enzyme inhibitor, biology.protein, Molecular Medicine, Signal transduction, Tyrosine kinase
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10
المؤلفون: Michael Snyder, Brendan D. Manning, Ramesh Padmanabha
المصدر: Molecular Biology of the Cell. 8:1829-1844
مصطلحات موضوعية: rho GTP-Binding Proteins, Binding Sites, Saccharomyces cerevisiae Proteins, Cell division, Saccharomyces cerevisiae, Cell Polarity, Cell Biology, GTPase, Biology, biology.organism_classification, Microtubules, Article, Pheromones, Cell biology, GTP-binding protein regulators, GTP-Binding Proteins, Microtubule, Cell polarity, Cytoskeleton, Molecular Biology, Cell Division, Actin
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11
المؤلفون: Ramesh Padmanabha, Yue-Zhong Shu, Judith A. Veitch, Marcella Donovan, Susan E. Lowe, Lynda S. Cook, Susan P. Manly, Stella Huang, Dolores M. Pirnik
المصدر: ChemInform. 29
مصطلحات موضوعية: chemistry.chemical_classification, biology, General Medicine, biology.organism_classification, chemistry.chemical_compound, Enzyme, chemistry, Biochemistry, Active compound, Ergot alkaloid, Penicillium, Agroclavine, Fermentation, Tyrosine kinase
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12
المؤلفون: Michael Snyder, Ramesh Padmanabha, Sonja Gehrung
المصدر: Molecular and General Genetics MGG. 229:1-9
مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Recombinant Fusion Proteins, Molecular Sequence Data, Restriction Mapping, Saccharomyces cerevisiae, Protein Serine-Threonine Kinases, Biology, SYT1, Fungal Proteins, Gene product, Open Reading Frames, CDC2 Protein Kinase, HSPA2, Gene cluster, Genetics, Gene family, Amino Acid Sequence, Molecular Biology, TAF15, Base Sequence, beta-Galactosidase, Kinetics, CDC37, Multigene Family, Mutation, Chromosome Deletion, Cyclin-dependent kinase 7, Protein Kinases, Sequence Alignment
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13
المؤلفون: Ramesh Padmanabha, C. V. C. Glover, D. E. Hanna, J. L.-P. Chen-Wu
المصدر: Molecular and Cellular Biology. 10:4089-4099
مصطلحات موضوعية: SCN3A, Casein kinase 2, alpha 1, Cell Biology, Casein kinase 1, Casein kinase 2, Biology, Casein kinases, MAP3K7, Molecular Biology, Molecular biology, Interleukin 10 receptor, alpha subunit, G alpha subunit
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14
المؤلفون: Donna M. Barten, Valerie Guss, Alice Loo, Sam Varma, Darcy G. Izzarelli, Larry R. Marcin, Jeremy H. Toyn, Craig Polson, Joanne J. Bronson, Kevin M. Felsenstein, Mcelhone Katharine E, Susan B. Roberts, Victoria Wong, Michael F. Parker, Jian Wang, Jason A. Corsa, Wengsheng Du, Ming Zheng, Ramesh Padmanabha, Roger Pak
المصدر: Bioorganicmedicinal chemistry letters. 17(21)
مصطلحات موضوعية: chemistry.chemical_classification, biology, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Caprolactam, Pharmaceutical Science, Aromatic amine, Biochemistry, Chemical synthesis, chemistry.chemical_compound, chemistry, In vivo, Enzyme inhibitor, Drug Discovery, Amyloid precursor protein, biology.protein, Lactam, Molecular Medicine, Amyloid Precursor Protein Secretases, Enzyme Inhibitors, Molecular Biology, Amyloid precursor protein secretase
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15
المؤلفون: Andrew J. Tebben, Joyce Dickey, Ramesh Padmanabha, Kim Esposito, Stephen R. Johnson, Wayne Vaccaro, Mark A. Hermsmeier, Michael R. Lawrence, Deborah A. Loughney, Angela Cacace, Victoria Wong, Michael A. Poss, Kristen Pike
المصدر: Journal of biomolecular screening. 12(2)
مصطلحات موضوعية: Process (engineering), Computer science, Wheat Germ Agglutinins, Monte Carlo method, Drug Evaluation, Preclinical, Sample (statistics), Biocompatible Materials, Bioinformatics, computer.software_genre, Disease cluster, Biochemistry, Sampling Studies, Analytical Chemistry, Receptors, G-Protein-Coupled, Inhibitory Concentration 50, Adenosine Triphosphate, Coumarins, Software Design, Fluorescence Resonance Energy Transfer, Cluster Analysis, Biotinylation, Computer Simulation, Fluorescent Dyes, Sampling (statistics), Receptor Protein-Tyrosine Kinases, Workload, Identification (information), Spectrophotometry, Molecular Medicine, Software design, Polystyrenes, Scintillation Counting, Fluorescein, Data mining, computer, Monte Carlo Method, Protein Kinases, Biotechnology
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16
المؤلفون: Henry F. De Fex, Derek J. Norris, Kamelia Behnia, Gary L. Schieven, Lynda S. Cook, Kathleen M. Gillooly, Qiong Fang, Arthur M. Doweyko, Robert V. Moquin, Suhong Pang, Kim W. McIntyre, Sidney Pitt, James Lin, Ding Ren Shen, Ramesh Padmanabha, John Wityak, Jagabandhu Das, Zhongqi Shen, Joel C. Barrish, Ping Chen, David J. Shuster
المصدر: Journal of medicinal chemistry. 49(23)
مصطلحات موضوعية: Lipopolysaccharides, Male, Models, Molecular, medicine.drug_class, Stereochemistry, T-Lymphocytes, Dasatinib, Administration, Oral, Carboxamide, In Vitro Techniques, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Src family kinase, Thiazole, Cell Proliferation, Inflammation, Mice, Inbred BALB C, Kinase, Tumor Necrosis Factor-alpha, Anti-Inflammatory Agents, Non-Steroidal, Arthritis, Experimental, Rats, Mice, Inbred C57BL, Thiazoles, Pyrimidines, src-Family Kinases, chemistry, Lymphocyte Specific Protein Tyrosine Kinase p56(lck), Rats, Inbred Lew, Chronic Disease, Molecular Medicine, Interleukin-2, Female, Proto-oncogene tyrosine-protein kinase Src, medicine.drug, Protein Binding
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17
المؤلفون: Susan P. Manly, Lynda S. Cook, Ramesh Padmanabha
المصدر: SLAS Discovery. 1:131-133
مصطلحات موضوعية: chemistry.chemical_compound, Chromatography, Lead (geology), Natural product, Chemistry, Molecular Medicine, Equilibrium dialysis, Biochemistry, Sizing, Analytical Chemistry, Biotechnology
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18
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19
المؤلفون: Susan P, Manly, Ramesh, Padmanabha, Susan E, Lowe
المصدر: Methods in molecular biology (Clifton, N.J.). 190
مصطلحات موضوعية: Microbiological Techniques, Biological Products, Plant Extracts, Drug Design, Drug Evaluation, Preclinical, Plants, Molecular Biology
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20
المؤلفون: Mark R. Witmer, Kenneth M. Tramposch, James R. Burke, Lynda B. Davern, R. Thomas Swann, Radmila Micanovic, Daniel Smith, Kurt R. Gregor, Joseph J. Villafranca, F. Christopher Zusi, Ramesh Padmanabha, Jeffrey Tredup, Susan P. Manly
المصدر: The Journal of biological chemistry. 274(27)
مصطلحات موضوعية: Stereochemistry, Lipid Bilayers, Phospholipid, Inositol 1,4,5-Trisphosphate, Phospholipase, Biochemistry, Phospholipases A, Choline, chemistry.chemical_compound, Phospholipase A2, Non-competitive inhibition, Humans, Scattering, Radiation, Lipid bilayer, Molecular Biology, Arachidonic Acid, biology, Calorimetry, Differential Scanning, Vesicle, Lasers, Substrate (chemistry), Water, Cell Biology, U937 Cells, Lipids, Dissociation constant, N-Formylmethionine Leucyl-Phenylalanine, Quaternary Ammonium Compounds, Kinetics, Phospholipases A2, Cholesterol, chemistry, biology.protein