نتائج البحث - "Ramana M. V. Reddy"

1

Abstract P5-05-04: A novel inhibitor of cancer stem cells overcomes chemotherapy resistance of triple negative breast cancers

المؤلفون: Stephen C. Cosenza, Amol Padgaonkar, Ramana M. V. Reddy, Hanna Y. Irie, E. Premkumar Reddy, Katsutoshi Sato, Stacey J. Baker

المصدر: Cancer Research. 80:P5-05

مصطلحات موضوعية: Cancer Research, Oncology, business.industry, Cancer stem cell, Cancer research, Medicine, business, Triple negative, Chemotherapy resistance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ddaf80635fb5ed5894dbc75b1320fa9e
https://doi.org/10.1158/1538-7445.sabcs19-p5-05-04

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2

Preclinical formulation for the pharmacokinetics and efficacy of GBO-006, a selective polo like kinase 2 (PLK2) inhibitor for the treatment of triple negative breast cancer

المؤلفون: Premkumar E Reddy, Sachin Bansal, Duraiswamy A. Jeyaraj, Srinivas Maddi, Joshodeep Boruwa, Chandra Deb, Pratima Srivastava, Srinivas Lenkalapelly, Ramana M. V. Reddy, Ravi Akkireddy, Manoj Maniar, Arnab Roy Chowdhury, Jang B. Gupta

المصدر: ADMET and DMPK
Volume 4
Issue 4

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f11725446af175e157820c766813bf
https://hrcak.srce.hr/171424

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3

Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias

المؤلفون: Ramana M. V. Reddy, Reddy Ep, Scott K. Shore, TA Newkirk, Leopold Lh

المصدر: Blood. 85:2162-2170

مصطلحات موضوعية: ABL, Immunology, breakpoint cluster region, Ribozyme, Cell Biology, Hematology, Gene rearrangement, Biology, Philadelphia chromosome, medicine.disease, Biochemistry, Molecular biology, Fusion gene, hemic and lymphatic diseases, biology.protein, medicine, VS ribozyme, Chronic myelogenous leukemia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8f5c3605fdf3de6e98cadd0f52adf33b
https://doi.org/10.1182/blood.v85.8.2162.bloodjournal8582162

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4

Abstract LB-A21: Single-agent activity and favorable pharmaceutical properties of orally bioavailable next-generation CDK4/6 inhibitor, ON 123300

المؤلفون: Chen Ren, Daniel Fox, Ramana M. V. Reddy, Muralidhar R. Mallireddigari, Benjamin S. Hoffman, Manoj Maniar

المصدر: Molecular Cancer Therapeutics. 14:LB-A21

مصطلحات موضوعية: Cancer Research, biology, Combination therapy, Chemistry, Pharmacology, Palbociclib, Intestinal absorption, Oncology, Cyclin-dependent kinase, biology.protein, Cyclin-dependent kinase 6, IC50, CDK inhibitor, ADME

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::65215e19244d476dddfa40290d0eef07
https://doi.org/10.1158/1535-7163.targ-15-lb-a21

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5

Folate-Polylysine-Mediated Delivery of a Multiunit Anti-BCRIABL Ribozyme to BCR/ABL-Transformed 32D Cells

المؤلفون: Scott K. Shore, Leopold Lh, Ramana M. V. Reddy, E. Premkumar Reddy

مصطلحات موضوعية: chemistry.chemical_compound, biology, Chemistry, Polylysine, Ribozyme, biology.protein, Cancer research, Molecular biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bdc46d297a1003699f74c43753f06028
https://doi.org/10.1385/0-89603-477-1:279

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6

Rigosertib Blocks RAS Signaling By Acting As a Small Molecule RAS Mimetic That Binds to the RAS-Binding Domains of RAS Effector Proteins

المؤلفون: Rodrigo Vasquez-Del Carpio, E. Premkumar Reddy, Kaushik Dutta, Aneel K. Aggarwal, Sai Krishna Athaluri Divakar, Ramana M. V. Reddy, Stacey J. Baker

المصدر: Blood. 124:5616-5616

مصطلحات موضوعية: MAPK/ERK pathway, Effector, Kinase, Proto-Oncogene Proteins c-akt, Immunology, Rigosertib, Cell Biology, Hematology, Biology, Biochemistry, Cell biology, Ral Guanine Nucleotide Exchange Factor, Kinase activity, Signal transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::15f6551dcf1e47a753789ea0ee9143cc
https://doi.org/10.1182/blood.v124.21.5616.5616

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7

Abstract 4537: Pharmacokinetics of PLK2 inhibitor GBO-006-1, developed as a novel first-in-class molecule to treat triple negative breast cancer

المؤلفون: Chandra Deb, Ramana M. V. Reddy, Shashidhar S. Jatiani, Stephen C. Cosenza, Arnab Roychowdhury, Amol Padgaonkar, Srinivasarao Maddi, Sayan Mitra, Premkumar E Reddy, Athisayamani Jeyaraj Duraiswamy, Manoj Maniar

المصدر: Cancer Research. 74:4537-4537

مصطلحات موضوعية: Volume of distribution, Cancer Research, biology, business.industry, medicine.medical_treatment, Safety pharmacology, hERG, Pharmacology, Targeted therapy, Oncology, Pharmacokinetics, In vivo, biology.protein, medicine, business, Triple-negative breast cancer, ADME

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::14b99c545b3774b87bed4558b212e19c
https://doi.org/10.1158/1538-7445.am2014-4537

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8

Abstract 4524: ON015640, a novel anti-cancer agent with tubulin depolymerizing activity

المؤلفون: Ramana M. V. Reddy, Benjamin S. Hoffman, Stephen C. Cosenza, Venkat Palella, EP Reddy

المصدر: Cancer Research. 71:4524-4524

مصطلحات موضوعية: Cancer Research, Drug discovery, Drug design, Biology, Bioinformatics, Cell biology, Nocodazole, chemistry.chemical_compound, Tubulin, Oncology, chemistry, Cancer cell, biology.protein, Mitosis, Mitotic catastrophe, Multipolar spindles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c90513b852b5f1e9c750b290358ac2ce
https://doi.org/10.1158/1538-7445.am2011-4524

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9

Synergistic Effects of a Novel Water-Soluble Small Molecule, ON 013105, and Rituximab on Mantle Cell Lymphoma In Vitro and In Vivo

المؤلفون: Amanda M. Gillum, Jerome E. Groopman, E. Premkumar Reddy, Ramana M. V. Reddy, Anil Prasad, Ashutosh Shrivastava

المصدر: Blood. 116:771-771

مصطلحات موضوعية: Vincristine, Programmed cell death, Chemistry, Immunology, Cell Biology, Hematology, Pharmacology, medicine.disease, Biochemistry, Cyclin D1, Apoptosis, In vivo, medicine, Cytotoxic T cell, Mantle cell lymphoma, Doxorubicin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fe61016cc79e1ed0545c23eed6c9cd2a
https://doi.org/10.1182/blood.v116.21.771.771

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10

Suppression of Cyclin D1 by on 01910.Na Is Associated with Decreased Survival of Trisomy 8 Myelodyplastic Bone Marrow Progenitors: A Potential Targetted Therapy

المؤلفون: Jerome S. Groopman, Premkumar E Reddy, Elaine M. Sloand, Ramana M. V. Reddy, Neal S. Young, Loretta Pfannes

المصدر: Blood. 110:822-822

مصطلحات موضوعية: Chromosome 7 (human), Pathology, medicine.medical_specialty, Immunology, Bone marrow failure, CD34, Cell Biology, Hematology, Biology, medicine.disease, Trisomy 8, Biochemistry, Molecular biology, Haematopoiesis, medicine.anatomical_structure, Survivin, Cancer cell, medicine, Bone marrow

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::93c2d51bff725453afc2d1f2139ddfc8
https://doi.org/10.1182/blood.v110.11.822.822

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