المؤلفون: Lara M. Marten, Ralph Krätzner, Gajja S. Salomons, Matilde Fernandez Ojeda, Peter Dechent, Jutta Gärtner, Peter Huppke, Steffi Dreha-Kulaczewski

المصدر: Molecular Genetics and Metabolism Reports, Vol 38, Iss , Pp 101053- (2024)

مصطلحات موضوعية: GAMT-deficiency, Neurometabolism, Neurodevelopmental disorder, MR-spectroscopy, Creatine-supplementation, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214426924000065; https://doaj.org/toc/2214-4269

URL الوصول: https://doaj.org/article/0af92ba593214a88806fa31c86bb9813

المؤلفون: Philipp Bengel, Manar Elkenani, Bo E. Beuthner, Maik Pietzner, Belal A. Mohamed, Beatrix Pollok-Kopp, Ralph Krätzner, Karl Toischer, Miriam Puls, Andreas Fischer, Lutz Binder, Gerd Hasenfuß, Moritz Schnelle

المصدر: Biomolecules, Vol 13, Iss 1, p 95 (2023)

مصطلحات موضوعية: severe aortic valve stenosis, hemodynamic subgroups, heart failure, metabolomics, metabolic remodeling, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-273X/13/1/95; https://doaj.org/toc/2218-273X

URL الوصول: https://doaj.org/article/a4f86f85d7124ef2af6260cd4b28a390

المؤلفون: Henry Gerd Klemp, Matthias Kettwig, Frank Streit, Jutta Gärtner, Hendrik Rosewich, Ralph Krätzner

المصدر: Metabolites, Vol 11, Iss 6, p 347 (2021)

مصطلحات موضوعية: peroxisome biogenesis disorder, Zellweger syndrome spectrum, metabolomics, membrane lipids, biomarker, biocrates, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-1989/11/6/347; https://doaj.org/toc/2218-1989

URL الوصول: https://doaj.org/article/ffc1ac75f56b44c78d27a8c9f57ee3d5

المؤلفون: Judith Buentzel, Henry Gerd Klemp, Ralph Kraetzner, Matthias Schulz, Gry Helene Dihazi, Frank Streit, Annalen Bleckmann, Kerstin Menck, Darius Wlochowitz, Claudia Binder

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13540

مصطلحات موضوعية: metabolic profiling, breast cancer, extracellular vesicles, biomarker, molecular breast cancer subtypes

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Oncology; https://dx.doi.org/10.3390/ijms222413540

الاتاحة: https://doi.org/10.3390/ijms222413540

المؤلفون: Frank Streit, Matthias Kettwig, Henry Gerd Klemp, Jutta Gärtner, Hendrik Rosewich, Stefan Nessler, Ralph Krätzner

المصدر: Journal of Inherited Metabolic Disease. 44:1174-1185

مصطلحات موضوعية: Autoimmune encephalitis, 0303 health sciences, Newborn screening, business.industry, Genetic enhancement, medicine.medical_treatment, 030305 genetics & heredity, Leukodystrophy, Hematopoietic stem cell transplantation, medicine.disease, Bioinformatics, Asymptomatic, 3. Good health, 03 medical and health sciences, Genetics, medicine, Biomarker (medicine), Adrenoleukodystrophy, medicine.symptom, business, Genetics (clinical), 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3060a9595941be34e98378915155d4f6
https://doi.org/10.1002/jimd.12389

المؤلفون: Anna V, Luebben, Daniel, Bender, Stefan, Becker, Lisa M, Crowther, Ilka, Erven, Kay, Hofmann, Johannes, Söding, Henry, Klemp, Cristina, Bellotti, Andreas, Stäuble, Tian, Qiu, Rahul S, Kathayat, Bryan C, Dickinson, Jutta, Gärtner, George M, Sheldrick, Ralph, Krätzner, Robert, Steinfeld

المصدر: Science advances. 8(15)

مصطلحات موضوعية: Neuronal Ceroid-Lipofuscinoses, Humans, Lysosome-Associated Membrane Glycoproteins, Membrane Proteins, Cysteine, Child

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::e3ef7c7a7e2eeb9375abdefcbc5c19ab
https://pubmed.ncbi.nlm.nih.gov/35427157

المؤلفون: Matthias, Kettwig, Henry, Klemp, Stefan, Nessler, Frank, Streit, Ralph, Krätzner, Hendrik, Rosewich, Jutta, Gärtner

المصدر: Journal of inherited metabolic diseaseREFERENCES. 44(5)

مصطلحات موضوعية: Male, Encephalomyelitis, Autoimmune, Experimental, Infant, Newborn, Lysophosphatidylcholines, ATP Binding Cassette Transporter, Subfamily D, Member 1, Mice, Inbred C57BL, Mice, Neonatal Screening, Neuroinflammatory Diseases, Animals, Humans, Metabolomics, Female, Dried Blood Spot Testing, Adrenoleukodystrophy, Biomarkers, Phospholipids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::a6a4c37109296647c95f28691696a1f5
https://pubmed.ncbi.nlm.nih.gov/33855724

المؤلفون: Marie-Christine Reinert, Holger Thiele, Susann Weissbach, Peter Nürnberg, Thorsten Rosenbaum, Ralph Krätzner, Jutta Gärtner, Janine Altmüller

المصدر: American Journal of Medical Genetics Part A. 173:2803-2807

مصطلحات موضوعية: Male, 0301 basic medicine, Mild phenotype, Mutation, Missense, Context (language use), Biology, Short stature, Leukoencephalopathy, 03 medical and health sciences, Leukoencephalopathies, Intellectual disability, Genetics, medicine, Humans, Missense mutation, Child, Genetics (clinical), Cullin Proteins, Prognosis, medicine.disease, Phenotype, 030104 developmental biology, CUL4B, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea028f0133284d67ec2ce38db283cc7
https://doi.org/10.1002/ajmg.a.38390

المؤلفون: Ronald J.A. Wanders, Sacha Ferdinandusse, Juliane Spiegler, Jutta Gärtner, Ralph Krätzner, Sabine Grønborg, Hans R. Waterham

المساهمون: Amsterdam Gastroenterology Endocrinology Metabolism, Laboratory Genetic Metabolic Diseases

المصدر: American journal of medical genetics. Part A, 152A(11), 2845-2849. Wiley-Liss Inc.

مصطلحات موضوعية: Male, medicine.medical_specialty, 17-Hydroxysteroid Dehydrogenases, DNA Mutational Analysis, Fluorescent Antibody Technique, Biology, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Peroxisomal Multifunctional Protein-2, Pregnancy, Internal medicine, Blood plasma, Genetics, Polymicrogyria, medicine, Peroxisomes, Missense mutation, Humans, Lymphocytes, Child, Genetics (clinical), Hydro-Lyases, 030304 developmental biology, 0303 health sciences, D-bifunctional protein deficiency, Pachygyria, Infant, Newborn, Peroxisome, medicine.disease, Magnetic Resonance Imaging, 3. Good health, Endocrinology, Neonatal hypotonia, Child, Preschool, Female, Nervous System Diseases, 030217 neurology & neurosurgery, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1654c35edbb7d2378d0cdea16fff9ff8
https://doi.org/10.1002/ajmg.a.33677

المؤلفون: Sabine Teichler, Corinna Dickel, Willhart Knepel, Payam Dibaj, Marcel Grapp, Julia Kitz, Ralph Krätzner

المصدر: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1789:403-412

مصطلحات موضوعية: Transcriptional Activation, endocrine system, PAX6 Transcription Factor, Protein Conformation, Molecular Sequence Data, Biophysics, Biology, Response Elements, Biochemistry, Glucagon, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Genetics, Transcriptional regulation, Animals, Paired Box Transcription Factors, Trypsin, Binding site, Eye Proteins, Promoter Regions, Genetic, Molecular Biology, Transcription factor, 030304 developmental biology, Homeodomain Proteins, 0303 health sciences, Base Sequence, DNA-binding domain, Transfection, Molecular biology, Peptide Fragments, eye diseases, Rats, Repressor Proteins, Glucagon-Secreting Cells, Data Interpretation, Statistical, Mutation, Homeobox, sense organs, PAX6, Sequence Alignment, 030217 neurology & neurosurgery, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40c2b83cb514bef53c757662dbf374b
https://doi.org/10.1016/j.bbagrm.2009.02.001

المؤلفون: Ralph Krätzner, Marcel Grapp, Willhart Knepel, Marian Pitulescu, Ulf Diederichsen

المصدر: European Journal of Organic Chemistry. 2008:2100-2106

مصطلحات موضوعية: 0303 health sciences, Phosphoramidite, Circular dichroism, 010405 organic chemistry, Chemistry, Stereochemistry, Organic Chemistry, 01 natural sciences, Oligomer, 0104 chemical sciences, 03 medical and health sciences, chemistry.chemical_compound, Biochemistry, Transcription (biology), Duplex (building), Phosphodiester bond, Physical and Theoretical Chemistry, Linker, DNA, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b044fad070a0d352f1e60dafbdb92269
https://doi.org/10.1002/ejoc.200701178

المؤلفون: Mohammad R. Toliat, Akinori Kimura, Nicholas J. Schork, Takeharu Hayashi, Peter Nürnberg, Jeroen Bakkers, Katrin Schäfer, Cornelia Schubert, Heinz-Peter Schultheiss, Jutta Schaper, Jeroen den Hertog, Gerd Hasenfuss, Ruben Postel, Dieter Kube, Ralph Knöll, Padmanabhan Vakeel, Kenton K. Murthy, Torbjorn Holm, Gudrun Knöll, Wolfgang Schaper, Brinda K. Rana, Gerrit Hennecke, Kenneth R. Chien, Erik Bos, Fredericus J.M. van Eeden, Andrei M. Vacaru, Peter J. Peters, Jianming Wang, Ralph Krätzner

المصدر: Circulation. 116:515-525

مصطلحات موضوعية: Male, Models, Molecular, Integrins, Embryo, Nonmammalian, Protein Conformation, DNA Mutational Analysis, Mutant, medicine.disease_cause, Epigenesis, Genetic, Laminin, Chlorocebus aethiops, Protein Interaction Mapping, Myocytes, Cardiac, Zebrafish, Genetics, Mutation, biology, Chromosome Mapping, Heart, Middle Aged, Extracellular Matrix, Pedigree, Cell biology, Codon, Nonsense, COS Cells, Female, Signal transduction, Cardiology and Cardiovascular Medicine, Protein Binding, Adult, Cardiomyopathy, Dilated, Integrin, Nonsense mutation, Mutation, Missense, Protein Serine-Threonine Kinases, Transfection, Physiology (medical), Cell Adhesion, medicine, Animals, Humans, Point Mutation, Integrin-linked kinase, Heart Failure, Myocardium, Endothelial Cells, Oligonucleotides, Antisense, Zebrafish Proteins, Protein Structure, Tertiary, Amino Acid Substitution, biology.protein, Genetic screen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3518994eea3bee12021c734b37ccaad9
https://doi.org/10.1161/circulationaha.107.689984

المؤلفون: C. Schlag, R. Blume, Anna Kutschenko, Elke Oetjen, Willhart Knepel, Roland Stein, Irmgard Cierny, Ralph Krätzner

المصدر: Diabetologia. 50:1678-1687

مصطلحات موضوعية: medicine.medical_specialty, Transcription, Genetic, Recombinant Fusion Proteins, Endocrinology, Diabetes and Metabolism, Blotting, Western, Interleukin-1beta, Mice, Transgenic, Biology, Mitogen-activated protein kinase kinase, Response Elements, Transfection, Cell Line, MAP2K7, Interferon-gamma, Mice, Cell Line, Tumor, Insulin-Secreting Cells, Internal medicine, Internal Medicine, medicine, Animals, Humans, Insulin, ASK1, Luciferases, MAPK14, Tumor Necrosis Factor-alpha, Akt/PKB signaling pathway, Cyclin-dependent kinase 4, Cyclin-dependent kinase 2, MAP Kinase Kinase Kinases, IRS2, Endocrinology, biology.protein, Cancer research, Maf Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d141696248415084676cfaae032476a8
https://doi.org/10.1007/s00125-007-0712-2

المؤلفون: Thomas Pape, George M. Sheldrick, Judit É. Debreczeni, Isabel Usón, Thomas R. Schneider, Alexander Wentzel, Ralph Krätzner, Harald Kolmar

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: molecular scaffolds, Scaffold, Stereochemistry, Trypsin inhibitor, 030303 biophysics, Plasma protein binding, Crystallography, X-Ray, Protein Engineering, EETI-II, 03 medical and health sciences, Structural Biology, inhibitors, medicine, Molecule, Plant Proteins, 030304 developmental biology, Hydrolase inhibitor, 0303 health sciences, Molecular Structure, biology, General Medicine, biology.organism_classification, Trypsin, Ecballium elaterium, Protease inhibitor (biology), 3. Good health, knottins, Cystine knots, Mutation, Trypsin Inhibitors, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0228729486894d360295c3e1716a60
https://doi.org/10.1107/s0907444905021207

المؤلفون: Sabine Horchler, Hans-Georg Schmidt, Herbert W. Roesky, Jiri Pinkas, Mathias Noltemeyer, Debashis Chakraborty, Ralph Krätzner, Isabel Usón, Saji P. Varkey

المصدر: Inorganic Chemistry. 40:2620-2624

مصطلحات موضوعية: Inorganic Chemistry, chemistry.chemical_compound, Crystallography, Monomer, 010405 organic chemistry, Chemistry, Yield (chemistry), Physical and Theoretical Chemistry, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, Ion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9233720f58486653e84868ea0f8bd27
https://doi.org/10.1021/ic000797v

المؤلفون: Peter Müller, Bodo Räke, Isabel Usón, Carsten Ackerhans, Ralph Krätzner, Herbert W. Roesky

المصدر: European Journal of Inorganic Chemistry. 2000:827-830

مصطلحات موضوعية: Inorganic Chemistry, Silicon, Chemistry, Inorganic chemistry, Chlorine, chemistry.chemical_element, Organic chemistry, Nitrogen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d2544580d2ffba809ba993ed89c3bf84
https://doi.org/10.1002/(sici)1099-0682(200005)2000:5<827::aid-ejic827>3.0.co;2-j

المؤلفون: Christopher Lehmann, Thomas R. Schneider, Isabel Usón, Ralph Krätzner, Nadia C. Mösch-Zanetti

المصدر: European Journal of Inorganic Chemistry. 2000:13-16

مصطلحات موضوعية: Inorganic Chemistry, chemistry.chemical_compound, chemistry, chemistry.chemical_element, Organic chemistry, Pyrazole, Redox, Titanium, Mercury (element)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c6d61acb276b5c435b0a36d130b5a4ad
https://doi.org/10.1002/(sici)1099-0682(200001)2000:1<13::aid-ejic13>3.0.co;2-n

المؤلفون: Kerstin Walter, Harald Kolmar, Ralph Krätzner, Andreas Christmann, Alexander Wentzel

المصدر: Protein Engineering, Design and Selection. 12:797-806

مصطلحات موضوعية: Protein Conformation, Recombinant Fusion Proteins, Molecular Sequence Data, Bioengineering, Biochemistry, Epitope, 03 medical and health sciences, Maltose-binding protein, Protein structure, Vegetables, Escherichia coli, Humans, Protease Inhibitors, Amino Acid Sequence, Molecular Biology, Peptide sequence, 030304 developmental biology, 0303 health sciences, Base Sequence, biology, Kunitz STI protease inhibitor, Cell Membrane, 030302 biochemistry & molecular biology, Cystine knot, Cell sorting, Flow Cytometry, Fusion protein, biology.protein, Cystine, Peptides, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e77e18f5bda2d761794aa6afc0b451c
https://doi.org/10.1093/protein/12.9.797

المؤلفون: Alexander Wentzel, Harald Kolmar, Ralph Krätzner, Andreas Christmann

المصدر: Journal of Biological Chemistry. 274:21037-21043

مصطلحات موضوعية: Protein Folding, Recombinant Fusion Proteins, Trypsin inhibitor, Biochemistry, Turn (biochemistry), 03 medical and health sciences, Escherichia coli, Molecular Biology, Gene Library, Plant Proteins, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Tetrapeptide, 030302 biochemistry & molecular biology, Cystine knot, Wild type, Sequence Analysis, DNA, Cell Biology, Plants, biology.organism_classification, Ecballium elaterium, Amino acid, chemistry, Trypsin Inhibitors, Bacterial outer membrane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d0aa1575e8d148b7eae1661d7a6683
https://doi.org/10.1074/jbc.274.30.21037

المؤلفون: Andrea, Thorn, Robert, Steinfeld, Marc, Ziegenbein, Marcel, Grapp, He-Hsuan, Hsiao, Henning, Urlaub, George M, Sheldrick, Jutta, Gärtner, Ralph, Krätzner

المصدر: Nucleic Acids Research

مصطلحات موضوعية: Models, Molecular, Protein Folding, Binding Sites, Glycosylation, Molecular Sequence Data, Crystallography, X-Ray, Zinc, Structural Homology, Protein, Structural Biology, Endoribonucleases, Mutation, Humans, Amino Acid Sequence, Copper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::d863a376a99d6c5b2f925b2589afabb4
https://pubmed.ncbi.nlm.nih.gov/22735700