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1Academic Journal
المؤلفون: Alexander Quaas, Lipika Goyal, Andrew X Zhu, Mark Cobbold, Dan G Duda, Rakesh K Jain, Kohei Shigeta, Aya Matsui, Hiroto Kikuchi, Sebastian Klein, Emilie Mamessier, Ivy X Chen, Shuichi Aoki, Shuji Kitahara, Koetsu Inoue, Ayako Shigeta, Tai Hato, Rakesh R Ramjiawan, Daniel Staiculescu, Dieter Zopf, Lukas Fiebig, Gabriela S Hobbs, Simona Dima, Irinel Popescu, Peigen Huang, Lance L Munn
المصدر: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Nisha Gupta, Hiroki Ochiai, Yoshinori Hoshino, Sebastian Klein, Jozef Zustin, Rakesh R. Ramjiawan, Shuji Kitahara, Nir Maimon, Despina Bazou, Sarah Chiang, Sen Li, Daniel H. Schanne, Rakesh. K. Jain, Lance L. Munn, Peigen Huang, Sergey V. Kozin, Dan G. Duda
المصدر: Cancers; Volume 15; Issue 4; Pages: 1021
مصطلحات موضوعية: prostate cancer, radiotherapy, SDF1α/CXCR4 signaling, primary lesions, bone metastases, orthotopic mouse models, vascular normalization
وصف الملف: application/pdf
Relation: Cancer Therapy; https://dx.doi.org/10.3390/cancers15041021
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3Academic Journal
المؤلفون: Wende Li, Sen Li, Ivy X. Chen, Yujiao Liu, Rakesh R. Ramjiawan, Chi-Ho Leung, Leo E. Gerweck, Dai Fukumura, Jay S. Loeffler, Rakesh K. Jain, Dan G. Duda, Peigen Huang
المصدر: Radiation Oncology, Vol 16, Iss 1, Pp 1-12 (2021)
مصطلحات موضوعية: Radiotherapy, Losartan, Angiotensin receptor blocker, Metastatic breast cancer, Mouse model, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1748-717X
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4Academic Journal
المؤلفون: Wende Li (4709158), Sen Li (155994), Ivy X. Chen (10258639), Yujiao Liu (646278), Rakesh R. Ramjiawan (10258642), Chi-Ho Leung (10258645), Leo E. Gerweck (10258648), Dai Fukumura (255871), Jay S. Loeffler (6029183), Rakesh K. Jain (158618), Dan G. Duda (158622), Peigen Huang (10258651)
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المؤلفون: Tai Hato, Shuichi Aoki, Mohammad Reza Nikmaneshi, Thomas Yau, Ivy X. Chen, Aya Matsui, Stefan Halvorsen, Mitesh J. Borad, Koetsu Inoue, Shuji Kitahara, Dan G. Duda, Rakesh K. Jain, Rakesh R. Ramjiawan, Daniel H. Schanne, Kazumichi Kawakubo, Patrick Sven Plum, Slim Sassi, Andrew X. Zhu, Hadi Tavakoli Nia, Masaaki Iwasaki, Lance L. Munn, Alexander Quaas, Hiroto Kikuchi, Jiang Chen, Xianfeng Chen, Kohei Shigeta, Irinel Popescu, Tyge C.E. Schmidt, Sebastian Klein, Simona Dima, Emilie Mamessier, Theodore S. Hong, Nabeel Bardeesy
المساهمون: Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Gut
Aoki, Shuichi; Inoue, Koetsu; Klein, Sebastian; Halvorsen, Stefan; Chen, Jiang; Matsui, Aya; Nikmaneshi, Mohammad R; Kitahara, Shuji; Hato, Tai; Chen, Xianfeng; Kawakubo, Kazumichi; Nia, Hadi T; Chen, Ivy; Schanne, Daniel H; Mamessier, Emilie; Shigeta, Kohei; Kikuchi, Hiroto; Ramjiawan, Rakesh R; Schmidt, Tyge Ce; Iwasaki, Masaaki; ... (2022). Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma. Gut, 71(1), pp. 185-193. BMJ Publishing Group 10.1136/gutjnl-2020-322493 <http://dx.doi.org/10.1136/gutjnl-2020-322493>
Gut, BMJ Publishing Group, 2021, pp.gutjnl-2020-322493. ⟨10.1136/gutjnl-2020-322493⟩
Gut, 2021, pp.gutjnl-2020-322493. ⟨10.1136/gutjnl-2020-322493⟩مصطلحات موضوعية: Placental growth factor, Stromal cell, medicine.medical_treatment, [SDV.CAN]Life Sciences [q-bio]/Cancer, 610 Medicine & health, Cholangiocarcinoma, 03 medical and health sciences, Mice, 0302 clinical medicine, Cancer-Associated Fibroblasts, Cell Line, Tumor, medicine, Animals, Humans, hepatic fibrosis, Hypoxia, PI3K/AKT/mTOR pathway, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, Placenta Growth Factor, 0303 health sciences, Chemotherapy, Hepatology, business.industry, Gastroenterology, Antibodies, Monoclonal, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, Hypoxia (medical), 3. Good health, Desmoplasia, Blockade, Bile Duct Neoplasms, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, Disease Progression, medicine.symptom, business, Myofibroblast
وصف الملف: application/pdf
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المؤلفون: Rakesh R. Ramjiawan, Shuichi Aoki, Hiroto Kikuchi, Rakesh K. Jain, Aya Matsui, Kohei Shigeta, Emilie Mamessier, Nabeel Bardeesy, Ivy X. Chen, Tai Hato, Shuji Kitahara, Dan G. Duda, Mark Cobbold, Peigen Huang, Hiroki Ochiai, Meenal Datta, Andrew X. Zhu
المساهمون: Massachusetts General Hospital [Boston], Keio University School of Medicine [Tokyo, Japan], Saitama Medical Center [Saitama, Japan], Tokyo Women's Medical University (TWMU), Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), Tohoku University Graduate School of Medicine, VU University Medical Center [Amsterdam], National Cancer Institute Central Hospital [Tokyo, Japan], Medical oncology laboratory, mamessier, emilie, Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Hepatobiliary Surg Nutr
Hepatology
Hepatology, Wiley-Blackwell, 2020, 71 (4), pp.1247-1261. ⟨10.1002/hep.30889⟩
Hepatology, 71(4), 1247-1261. John Wiley and Sons Ltd
Shigeta, K, Datta, M, Hato, T, Kitahara, S, Chen, I X, Matsui, A, Kikuchi, H, Mamessier, E, Aoki, S, Ramjiawan, R R, Ochiai, H, Bardeesy, N, Huang, P, Cobbold, M, Zhu, A X, Jain, R K & Duda, D G 2020, ' Dual Programmed Death Receptor-1 and Vascular Endothelial Growth Factor Receptor-2 Blockade Promotes Vascular Normalization and Enhances Antitumor Immune Responses in Hepatocellular Carcinoma ', Hepatology, vol. 71, no. 4, pp. 1247-1261 . https://doi.org/10.1002/hep.30889
Hepatology, 2020, 71 (4), pp.1247-1261. ⟨10.1002/hep.30889⟩مصطلحات موضوعية: 0301 basic medicine, Chemokine, Carcinoma, Hepatocellular, Programmed Cell Death 1 Receptor, [SDV.CAN]Life Sciences [q-bio]/Cancer, Angiogenesis Inhibitors, Antibodies, Mice, 03 medical and health sciences, Paracrine signalling, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Immune system, [SDV.CAN] Life Sciences [q-bio]/Cancer, Cell Line, Tumor, Spheroids, Cellular, Antineoplastic Combined Chemotherapy Protocols, Tumor-Associated Macrophages, medicine, Animals, Cytotoxic T cell, ComputingMilieux_MISCELLANEOUS, Neovascularization, Pathologic, Hepatology, biology, business.industry, Monocyte, Liver Neoplasms, Kinase insert domain receptor, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, Neoplasms, Experimental, Vascular Endothelial Growth Factor Receptor-2, 3. Good health, Blockade, Editorial, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Cancer research, 030211 gastroenterology & hepatology, [SDV.IMM.IMM] Life Sciences [q-bio]/Immunology/Immunotherapy, business, CD8, T-Lymphocytes, Cytotoxic
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المؤلفون: Dan G. Duda, Arjan W. Griffioen, Rakesh R. Ramjiawan
المصدر: Ramjiawan, R R, Griffioen, A W & Duda, D G 2017, ' Anti-angiogenesis for cancer revisited : Is there a role for combinations with immunotherapy? ', Angiogenesis, vol. 20, no. 2, pp. 185-204 . https://doi.org/10.1007/s10456-017-9552-y
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, 0301 basic medicine, Cancer Research, Physiology, Angiogenesis, medicine.medical_treatment, Clinical Biochemistry, Angiogenesis Inhibitors, Vascular permeability, Biology, Article, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, Chemotherapy, Neovascularization, Pathologic, Cancer, Immunotherapy, Hypoxia (medical), medicine.disease, Immune checkpoint, Neoplasm Proteins, Blockade, Survival Rate, Receptors, Vascular Endothelial Growth Factor, 030104 developmental biology, 030220 oncology & carcinogenesis, Immunology, Cancer research, medicine.symptom
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المؤلفون: Eleanor Minogue, James M. Heather, Rakesh R. Ramjiawan, Dai Fukumura, Songfa Zhang, Takashi Nojiri, Keehoon Jung, Leif W. Ellisen, Aditya Bardia, Laura T. Morton, Aaron N. Hata, Li Wan, Sean Sepulveda, Nisha Gupta, Ashok Khatri, Ryan B. Corcoran, Kohei Shigeta, Ricky Joseph, Feng Shi, Sara I. Pai, David Millar, Kosuke Kawaguchi, Jiang Chen, William Ho, Dan G. Duda, Mark Cobbold, Shuichi Aoki, Ivy X. Chen, Rakesh K. Jain
المصدر: Nature biotechnology. 38(4)
مصطلحات موضوعية: animal structures, Immunoconjugates, medicine.medical_treatment, Biomedical Engineering, Cytomegalovirus, Epitopes, T-Lymphocyte, Bioengineering, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Applied Microbiology and Biotechnology, Immunotherapy, Adoptive, Epitope, Antibodies, Immunomodulation, 03 medical and health sciences, Mice, 0302 clinical medicine, Antigen, Cancer immunotherapy, Cell Line, Tumor, Neoplasms, medicine, Animals, Humans, 030304 developmental biology, 0303 health sciences, biology, business.industry, Histocompatibility Antigens Class I, Cancer, Immunotherapy, medicine.disease, Immune checkpoint, Matrix Metalloproteinases, biology.protein, Cancer research, Molecular Medicine, Antibody, business, 030217 neurology & neurosurgery, CD8, Biotechnology
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المؤلفون: Peigen Huang, Ivy X. Chen, Meenal Datta, Rakesh K. Jain, Hiroto Kikuchi, Hiroki Ochiai, Tai Hato, Kohei Shigeta, Shuichi Aoki, Aya Matsui, Nabeel Bardeesy, Shuji Kitihara, Andrew X. Zhu, Rakesh R. Ramjiawan, Dan G. Duda, Mark Cobbold, Emilie Mamessier
المصدر: Cancer Immunology Research. 8:B89-B89
مصطلحات موضوعية: Cancer Research, biology, business.industry, VEGF receptors, Immunology, Vascular normalization, medicine.disease, Blockade, Immune system, Hepatocellular carcinoma, Cancer research, medicine, biology.protein, business
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المؤلفون: Peigen Huang, Sylvie Roberge, Yunching Chen, Rakesh K. Jain, Andrew X. Zhu, Gregory Y. Lauwers, Dan G. Duda, Christopher Fan, Thomas Reiberger, Nabeel Bardeesy, Rekha Samuel, Tai Hato, Rakesh R. Ramjiawan
المساهمون: Medical oncology laboratory, CCA - Innovative therapy
المصدر: Reiberger, T, Chen, Y C, Ramjiawan, R R, Hato, T, Fan, C, Samuel, R, Roberge, S, Huang, P G, Lauwers, G Y, Zhu, A X, Bardeesy, N, Jain, R K & Duda, D G 2015, ' An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis ', Nature Protocols, vol. 10, no. 8, pp. 1264-1274 . https://doi.org/10.1038/nprot.2015.080
Nature Protocols, 10(8), 1264-1274. Nature Publishing Groupمصطلحات موضوعية: Liver Cirrhosis, Mice, Inbred C3H, Cirrhosis, Carcinoma, Hepatocellular, business.industry, Liver Neoplasms, Transplantation, Heterologous, Tumor initiation, medicine.disease, General Biochemistry, Genetics and Molecular Biology, digestive system diseases, Article, Transplantation, Liver Neoplasms, Experimental, Fibrosis, Hepatocellular carcinoma, Immunology, Carcinoma, medicine, Cancer research, Animals, Liver cancer, Hepatic fibrosis, business, Carbon Tetrachloride
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المؤلفون: Z. Alexander Cao, Dan G. Duda, Qing Sheng, Melinda E. Sanders, Ram C. Shankaraiah, David P. Kodack, Dai Fukumura, Jonas Kloepper, C. Ryan Miller, Alan Huang, Angela Tam, Gino B. Ferraro, Kamila Naxerova, Carey K. Anders, Carlotta Costa, Jantima Tanboon, Xiaolong Qi, Carlos L. Arteaga, Rakesh K. Jain, Yongchul Song, Elena F. Brachtel, Rita Das, Jeffrey A. Engelman, Divya Bezwada, Robert Schlegel, Mark Badeaux, Monica V. Estrada, Christina S. F. Wong, Marni B. Siegel, Shom Goel, Vasileios Askoxylakis, Rakesh R. Ramjiawan, Bhushankumar Patel
مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, Receptor, ErbB-3, Antineoplastic Agents, Breast Neoplasms, Disease, Article, Mice, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, medicine, Animals, Tumor growth, Receptor, skin and connective tissue diseases, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Brain Neoplasms, business.industry, General Medicine, Therapeutic resistance, medicine.disease, Blockade, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Phosphorylation, Female, business
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المؤلفون: Chun Hung Liu, Annique M M J Duyverman, Shuji Kitahara, Dan G. Duda, Kuo Shyang Jeng, Chiung Fang Chang, Yun Chieh Sung, Rakesh R. Ramjiawan, Chih-Chun Chang, Ya Chi Liu, Simona Dima, Rakesh K. Jain, Peigen Huang, Andrew X. Zhu, Dong Yu Gao, Keith T. Flaherty, Irinel Popescu, Fu Fei Hsu, Yunching Chen, Cyril H. Benes, Nabeel Bardeesy, Ts Ting Lin
المساهمون: Medical oncology laboratory, CCA - Cancer Treatment and quality of life
المصدر: Scientific Reports
Chen, Y, Liu, Y C, Sung, Y C, Ramjiawan, R R, Lin, T T, Chang, C C, Jeng, K S, Chang, C F, Liu, C H, Gao, D Y, Hsu, F F, Duyverman, A M, Kitahara, S, Huang, P, Dima, S, Popescu, I, Flaherty, K T, Zhu, A X, Bardeesy, N, Jain, R K, Benes, C H & Duda, D G 2017, ' Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors ', Scientific Reports, vol. 7, 44123 . https://doi.org/10.1038/srep44123
Scientific Reports, 7:44123. Nature Publishing Groupمصطلحات موضوعية: 0301 basic medicine, Oncology, Sorafenib, MAPK/ERK pathway, Niacinamide, medicine.medical_specialty, Receptors, CXCR4, Carcinoma, Hepatocellular, Article, Cell Line, 03 medical and health sciences, Transactivation, Mice, 0302 clinical medicine, Drug Delivery Systems, Downregulation and upregulation, Internal medicine, medicine, Animals, Humans, Protein kinase A, neoplasms, Protein Kinase Inhibitors, Multidisciplinary, Chemistry, Phenylurea Compounds, Liver Neoplasms, HCCS, digestive system diseases, 3. Good health, Neoplasm Proteins, 030104 developmental biology, Apoptosis, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Nanoparticles, Benzimidazoles, medicine.drug
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المؤلفون: Peigen Huang, Rakesh R. Ramjiawan, Tai Hato, Rakesh K. Jain, Hiroki Ochiai, Elizabeth C. Unan, Andrew X. Zhu, Shuji Kitahara, Dan G. Duda, Yuhui Huang, Christopher Fan, Mei Rosa Ng, Yunching Chen, Tejaswini P. Reddy, Thomas Reiberger, Nabeel Bardeesy
المساهمون: Medical oncology laboratory, CCA - Innovative therapy
المصدر: Hepatology, 61(5), 1591-1602. John Wiley and Sons Ltd
Chen, Y C, Ramjiawan, R R, Reiberger, T, Ng, M R, Hato, T, Huang, Y H, Ochiai, H, Kitahara, S, Unan, E C, Reddy, T P, Fan, C, Huang, P G, Bardeesy, N, Zhu, A X, Jain, R K & Duda, D G 2015, ' CXCR4 Inhibition in Tumor Microenvironment Facilitates Anti-Programmed Death Receptor-1 Immunotherapy in Sorafenib-Treated Hepatocellular Carcinoma in Mice ', Hepatology, vol. 61, no. 5, pp. 1591-1602 . https://doi.org/10.1002/hep.27665مصطلحات موضوعية: Niacinamide, Sorafenib, Receptors, CXCR4, Carcinoma, Hepatocellular, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Antineoplastic Agents, Biology, Article, Mice, Immune system, Tumor Microenvironment, medicine, Animals, Humans, Protein Kinase Inhibitors, neoplasms, Tumor microenvironment, Hepatology, Phenylurea Compounds, Liver Neoplasms, Immunosuppression, Immunotherapy, medicine.disease, digestive system diseases, Hepatocellular carcinoma, Immunology, Cancer research, Tyrosine kinase, CD8, medicine.drug
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المؤلفون: Christina Wong, Dai Fukumura, Jantima Tanboon, Valeria M. Estrada, Alexander Cao, Rita Das, Carlos L. Arteaga, Alan Huang, Jeffrey A. Engelman, Robert Schlegel, Dan G. Duda, Divya Bezwada, Mark Badeaux, David P. Kodack, Gino B. Ferraro, Elena F. Brachtel, Ram C. Shankaraiah, Carlotta Costa, Marni B. Siegel, Angela Tam, Vasileios Askoxylakis, Youngchul Song, Bhushankumar Patel, Shom Goel, Rakesh R. Ramjiawan, Melinda E. Sanders, Qing Sheng, Carey K. Anders, Ryan Miller, Xiaolong Qi, Jonas Kloepper, Rakesh K. Jain, Kamila Naxerova
المصدر: Cancer Research. 77:5008-5008
مصطلحات موضوعية: Cancer Research, business.industry, Cancer, Therapeutic resistance, medicine.disease, Blockade, Breast cancer, Oncology, Immunology, medicine, Cancer research, Brain lesions, Tumor growth, business, PI3K/AKT/mTOR pathway
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المؤلفون: Ts-Ting Lin, Rakesh R. Ramjiawan, Ya-Chi Liu, Yunching Chen, Dan G. Duda
المصدر: Cancer Research. 76:1315-1315
مصطلحات موضوعية: Oncology, MAPK/ERK pathway, Sorafenib, Cancer Research, medicine.medical_specialty, business.industry, Angiogenesis, Cell, Cancer, medicine.disease, digestive system diseases, medicine.anatomical_structure, Downregulation and upregulation, Hepatocellular carcinoma, Internal medicine, Cancer research, Medicine, Viability assay, business, neoplasms, medicine.drug
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المؤلفون: Rakesh K. Jain, Mei Rosa Ng, Tai Hato, Peigen Huang, Andrew X. Zhu, Tejaswini P. Reddy, Dan G. Duda, Hiroki Ochiai, Rakesh R. Ramjiawan, Yunching Chen, Elizabeth C. Unan, Thomas Reiberger
المصدر: Cancer Immunology Research. 3:B79-B79
مصطلحات موضوعية: Sorafenib, Cancer Research, Tumor microenvironment, business.industry, medicine.drug_class, medicine.medical_treatment, Immunology, Immunotherapy, medicine.disease, digestive system diseases, Immune checkpoint, Tyrosine-kinase inhibitor, Metastasis, Desmoplasia, Hepatocellular carcinoma, medicine, Cancer research, medicine.symptom, business, medicine.drug
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المؤلفون: Yuhui Huang, C. Fan, Tai Hato, Rakesh R. Ramjiawan, Thomas Reiberger, Dan G. Duda, Nabeel Bardeesy, Andrew X. Zhu, Rakesh K. Jain, P. Huang, Elizabeth C. Unan, C. Yunching, R.R. Ng, Tejaswini P. Reddy
المصدر: Journal of Hepatology. 62:S416
مصطلحات موضوعية: Sorafenib, Tumor microenvironment, Hepatology, business.industry, medicine.medical_treatment, Anti pd 1, Immunotherapy, medicine.disease, CXCR4, Hepatocellular carcinoma, Immunology, medicine, Cancer research, business, medicine.drug