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1Academic Journal
المؤلفون: Caroline Gubser Keller, Youngah Shin, Alex Mas Monteys, Nicole Renaud, Martin Beibel, Natalia Teider, Thomas Peters, Thomas Faller, Sophie St-Cyr, Judith Knehr, Guglielmo Roma, Alejandro Reyes, Marc Hild, Dmitriy Lukashev, Diethilde Theil, Natalie Dales, Jang-Ho Cha, Beth Borowsky, Ricardo Dolmetsch, Beverly L. Davidson, Rajeev Sivasankaran
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2Academic Journal
المؤلفون: Diethilde Theil, Reginald Valdez, Katy Darribat, Arno Doelemeyer, Rajeev Sivasankaran, Andreas Hartmann
المصدر: Biology Open, Vol 10, Iss 10 (2021)
مصطلحات موضوعية: imaging, immunohistochemistry, mouse, rat, dog, neurogenesis, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Sandipan Chatterjee, Joseph D Szustakowski, Nirmala R Nanguneri, Craig Mickanin, Mark A Labow, Axel Nohturfft, Kumlesh K Dev, Rajeev Sivasankaran
المصدر: PLoS ONE, Vol 4, Iss 4, p e5197 (2009)
وصف الملف: electronic resource
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4Academic Journal
المؤلفون: Jake Axford (6081920), Moo Je Sung (2085337), John Manchester (2303572), Donovan Chin (1612576), Monish Jain (1948042), Youngah Shin (6059), Ina Dix (1639147), Lawrence G. Hamann (1436563), Atwood K. Cheung (1920859), Rajeev Sivasankaran (264843), Karin Briner (2725954), Natalie A. Dales (2990565), Brian Hurley (6081917)
مصطلحات موضوعية: Biochemistry, Genetics, Neuroscience, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, 2- fluorophenyl thiadiazole motif, exon -7 inclusion, survival motor neuron protein, gene SMN 2, SMA, 2- hydroxyphenyl pyridazine core, SMN protein, intramolecular hydrogen bond, survival motor neuron 1
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5
المؤلفون: Lawren VandeVrede, Amy Wolf, Elisabeth H. Thijssen, Joel H. Kramer, Howard J. Rosen, Renaud La Joie, Corrina Fonseca, Kaj Blennow, Yann Cobigo, Andreas Jeromin, Marie-Anne Valentin, Adam L. Boxer, Oskar Hansson, Lili Yu, Salvatore Spina, Niklas Mattsson-Carlgren, Amelia Strom, Bradley F. Boeve, Bruce L. Miller, Charlotte E. Teunissen, Jeffrey L. Dage, William W. Seeley, Lea T. Grinberg, Arvind Kinhikar, Gil D. Rabinovici, Argentina Lario Lago, Agnieszka Kieloch, Leonardo Iaccarino, Nicholas K. Proctor, Treatment for Frontotemporal Lobar Degeneration investigators, Rajeev Sivasankaran, Hilary W. Heuer, Julio C. Rojas, Danielle Graham, Suzanne L. Baker, Isabel E. Allen, Henrik Zetterberg
المساهمون: Laboratory Medicine, Obstetrics and gynaecology, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Neuroinfection & -inflammation
المصدر: The Lancet Neurology, 20(9), 739-752. Lancet Publishing Group
Advancing Research and Treatment for Frontotemporal Lobar Degeneration investigators 2021, ' Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study ', The Lancet Neurology, vol. 20, no. 9, pp. 739-752 . https://doi.org/10.1016/S1474-4422(21)00214-3
The Lancet. Neurology, vol 20, iss 9مصطلحات موضوعية: Male, Oncology, Aging, Disease, Neurodegenerative, Alzheimer's Disease, Primary progressive aphasia, Diagnosis, 80 and over, 2.1 Biological and endogenous factors, Medicine, Aetiology, Phosphorylation, Aged, 80 and over, screening and diagnosis, Frontotemporal lobar degeneration, Middle Aged, Advancing Research and Treatment for Frontotemporal Lobar Degeneration investigators, Frontotemporal Dementia (FTD), Detection, Neurological, Biomedical Imaging, Female, 4.2 Evaluation of markers and technologies, Frontotemporal dementia, Adult, medicine.medical_specialty, Clinical Trials and Supportive Activities, Clinical Sciences, tau Proteins, Progressive supranuclear palsy, Diagnosis, Differential, Rare Diseases, Clinical Research, Alzheimer Disease, Predictive Value of Tests, Internal medicine, mental disorders, Acquired Cognitive Impairment, Humans, Dementia, Cognitive Dysfunction, Aged, Retrospective Studies, Neurology & Neurosurgery, Amyloid beta-Peptides, business.industry, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Posterior cortical atrophy, medicine.disease, Brain Disorders, Positron-Emission Tomography, Differential, Neurology (clinical), Frontotemporal Lobar Degeneration, Differential diagnosis, business, Biomarkers
وصف الملف: application/pdf
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6
المؤلفون: Youngah Shin, Moo Je Sung, Monish Jain, Jake Axford, Natalie Dales, Ina Dix, Brian Hurley, Lawrence G. Hamann, Karin Briner, Atwood K. Cheung, John I. Manchester, Donovan N. Chin, Rajeev Sivasankaran
المصدر: Journal of Medicinal Chemistry. 64:4744-4761
مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, Hydrogen bond, Stereochemistry, Aryl, SMN1, 01 natural sciences, nervous system diseases, 0104 chemical sciences, Pyridazine, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, chemistry, Intramolecular force, Drug Discovery, RNA splicing, Molecular Medicine, Non-covalent interactions, Amine gas treating, 030304 developmental biology
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7
المؤلفون: Caroline Gubser Keller, Youngah Shin, Alex Mas Monteys, Nicole Renaud, Martin Beibel, Natalia Teider, Thomas Peters, Thomas Faller, Sophie St-Cyr, Judith Knehr, Guglielmo Roma, Alejandro Reyes, Marc Hild, Dmitriy Lukashev, Diethilde Theil, Natalie Dales, Jang-Ho Cha, Beth Borowsky, Ricardo Dolmetsch, Beverly L. Davidson, Rajeev Sivasankaran
المصدر: Nature communications. 13(1)
مصطلحات موضوعية: Disease Models, Animal, Huntingtin Protein, Mice, Multidisciplinary, Huntington Disease, General Physics and Astronomy, Animals, Brain, Humans, General Chemistry, Oligonucleotides, Antisense, Trinucleotide Repeat Expansion, General Biochemistry, Genetics and Molecular Biology
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8
المؤلفون: Luis Tecedor, Rajeev Sivasankaran, Beverly L. Davidson, Amy Muehlmatt, Euyn Lim, Alex Mas Monteys, Amiel A Hundley, Paul T. Ranum, Dmitriy Lukashev
المصدر: Nature
مصطلحات موضوعية: Male, Computational biology, Biology, Article, Muscular Atrophy, Spinal, Mice, Drug Delivery Systems, Progranulins, Genome editing, Neuronal Ceroid-Lipofuscinoses, CRISPR-Associated Protein 9, Animals, Humans, Inducer, Gene, Erythropoietin, Gene Editing, Multidisciplinary, HEK 293 cells, Robustness (evolution), Brain, Translation (biology), Exons, Genetic Therapy, Small molecule, Survival of Motor Neuron 1 Protein, Mice, Inbred C57BL, Survival of Motor Neuron 2 Protein, Alternative Splicing, HEK293 Cells, Liver, Frontotemporal Dementia, Protein Biosynthesis, RNA splicing, Female
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9
المؤلفون: Jake, Axford, Moo Je, Sung, John, Manchester, Donovan, Chin, Monish, Jain, Youngah, Shin, Ina, Dix, Lawrence G, Hamann, Atwood K, Cheung, Rajeev, Sivasankaran, Karin, Briner, Natalie A, Dales, Brian, Hurley
المصدر: Journal of medicinal chemistry. 64(8)
مصطلحات موضوعية: Male, Motor Neurons, RNA Splicing, Molecular Conformation, Survival of Motor Neuron 1 Protein, Rats, Muscular Atrophy, Spinal, Oxygen, Pyridazines, Rats, Sprague-Dawley, Survival of Motor Neuron 2 Protein, Mice, Structure-Activity Relationship, Halogens, Drug Design, Thiadiazoles, Animals, Humans, Sulfur, Half-Life
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10
المؤلفون: David C. Perry, Adam M. Staffaroni, Renaud La Joie, Joel H. Kramer, Henrik Zetterberg, Anna Karydas, Adam L. Boxer, Alberto Lleó, Lea T. Grinberg, Gil D. Rabinovici, Giovanni Coppola, Maria Luisa Gorno-Tempini, Salvatore Spina, Howard J. Rosen, Bruce L. Miller, Eliana Marisa Ramos, Julio C. Rojas, Ignacio Illán-Gala, Kaj Blennow, Rajeev Sivasankaran, William W. Seeley
المصدر: NEUROLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Neurology
Neurology, vol 96, iss 5مصطلحات موضوعية: Male, Aging, Pathology, Amyloid pet, Neurodegenerative, Neuropsychological Tests, Alzheimer's Disease, 0302 clinical medicine, Neurofilament Proteins, 2.1 Biological and endogenous factors, Medicine, 030212 general & internal medicine, Aetiology, medicine.diagnostic_test, Brain, Frontotemporal lobar degeneration, Middle Aged, Magnetic Resonance Imaging, DNA-Binding Proteins, Survival Rate, Frontotemporal Dementia (FTD), Neurological, Disease Progression, Cognitive Sciences, Female, Alzheimer's disease, Adult, medicine.medical_specialty, Neurofilament light, Clinical Trials and Supportive Activities, Clinical Sciences, tau Proteins, Sensitivity and Specificity, Article, 03 medical and health sciences, Disease severity, Clinical Research, Alzheimer Disease, mental disorders, Acquired Cognitive Impairment, Humans, Survival rate, Aged, Neurology & Neurosurgery, Amyloid beta-Peptides, business.industry, Neurosciences, Case-control study, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), nutritional and metabolic diseases, Magnetic resonance imaging, medicine.disease, Brain Disorders, nervous system diseases, Case-Control Studies, Positron-Emission Tomography, RNA-Binding Protein FUS, Dementia, Neurology (clinical), Frontotemporal Lobar Degeneration, business, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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11
المؤلفون: Salvatore Spina, Renaud La Joie, Adam M. Staffaroni, Rajeev Sivasankaran, William W. Seeley, Ignacio Illán-Gala, Adam L. Boxer, Henrik Zetterberg, Howard J. Rosen, Maria Luisa Gorno Tempini, Anna Karydas, Eliana Marisa Ramos, Joel H. Kramer, Alberto Lleó, Gil D. Rabinovici, Lea T. Grinberg, Julio C. Rojas, David C. Perry, Giovanni Coppolla
المصدر: Alzheimer's & Dementia. 16
مصطلحات موضوعية: Epidemiology, Blood based biomarkers, business.industry, Health Policy, Neurofilament light, Neurodegeneration, Disease, medicine.disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Neuroimaging, medicine, Neurology (clinical), Geriatrics and Gerontology, business, Neuroscience, Frontotemporal dementia
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12
المؤلفون: Natalie Dales, Monish Jain, Sanchez Carina Cristina, Ryan Kerrigan, Atwood K. Cheung, Cary Fridrich, Donovan N. Chin, Brian Hurley, Keith Hoffmaster, Lin Deng, Ronald Tomlinson, Marc Hild, Rajeev Sivasankaran, Jake Axford, Aleem Fazal, Gary O’Brien, Christopher Towler, Mailin Van Hoosear, Youngah Shin, Dione Kobayashi, Shen Yiping, Lei Shu, William F. Dietrich, Karen S. Chen, Lawrence G. Hamann, Karin Briner, Rebecca Servais, Cheng Song, Emma Cody, Robert Sun, Daniel Curtis, Moo Je Sung, Ying Hou
المصدر: Journal of Medicinal Chemistry. 61:11021-11036
مصطلحات موضوعية: 0301 basic medicine, ERG1 Potassium Channel, Spliceosome, RNA Splicing, Phenotypic screening, Drug Evaluation, Preclinical, Administration, Oral, Quantitative Structure-Activity Relationship, SMN1, Crystallography, X-Ray, Cell Line, Muscular Atrophy, Spinal, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Animals, Humans, Gene, Motor Neurons, Dose-Response Relationship, Drug, Chemistry, Brain, Spinal muscular atrophy, Motor neuron, medicine.disease, SMA, Survival of Motor Neuron 1 Protein, nervous system diseases, Mice, Inbred C57BL, Pyridazines, Survival of Motor Neuron 2 Protein, 030104 developmental biology, medicine.anatomical_structure, RNA splicing, Molecular Medicine, Neuroscience, 030217 neurology & neurosurgery
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13
المؤلفون: Alex Mas Monteys, Amiel A. Hundley, Paul T. Ranum, Luis Tecedor, Amy Muehlmatt, Euyn Lim, Dmitriy Lukashev, Rajeev Sivasankaran, Beverly L. Davidson
المصدر: Nature. 602:E25-E25
مصطلحات موضوعية: Multidisciplinary
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14
المؤلفون: Deeba N. Syed, Asfa Ali, Jun Qi, Rajeev Sivasankaran, Graham S. Erwin, Mousheng Xu, Istaq Ahmad, Md. Ashraf, Asuka Eguchi, Matthew A. Lawlor, Deepak Kumar, Justin J. Jeffery, James E. Bradner, Katie A. Worringer, Aseem Z. Ansari, Anna McNally, Natalia Teider, Achal Kumar Srivastava, Paul M.C. Park, Matthew P. Grieshop, Hasan Mukhtar, Mohammed Faruq
المصدر: Science. 358:1617-1622
مصطلحات موضوعية: Transcriptional Activation, 0301 basic medicine, Multidisciplinary, Transcription, Genetic, biology, Transcription elongation, RNA polymerase II, Small molecule, Chromatin, Article, Cell biology, 03 medical and health sciences, 030104 developmental biology, Friedreich Ataxia, Transcription (biology), Iron-Binding Proteins, biology.protein, Frataxin, Humans, Gene Silencing, RNA Polymerase II, Transcriptional Elongation Factors, Elongation, Gene
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15
المؤلفون: Xiaolu Zhang, Jeffery A. Porter, Atwood K. Cheung, Vic E. Myer, Mark C. Fishman, Caroline Gubser Keller, Rajeev Sivasankaran, John A. Tallarico, Marc Hild, Sven Schuierer, Michael McLellan, Frada Berenshteyn, William F. Dietrich, Cecile Blaustein, Youngah Shin, Lei Shu, Michael Salcius, Monish Jain, Mailin Van Hoosear, Donovan N. Chin, Arnaud Lacoste, Martin Beibel, James Palacino, Nicole A. Renaud, Leo Murphy, Marcel J. J. Blommers, Lawrence G. Hamann, Caroline Bullock, Xiaoying Shi, Lin Deng, Jason R. Thomas, Daniel Curtis, Thomas M. Smith, Susanne E. Swalley, Gregory A. Michaud, Cheng Song, Brian Tseng, Guglielmo Roma, Natalie Dales, Rebecca Servais
المصدر: Nature Chemical Biology. 11:511-517
مصطلحات موضوعية: Models, Molecular, Gene Expression, Mice, Transgenic, SMN1, Biology, Ribonucleoprotein, U1 Small Nuclear, Muscular Atrophy, Spinal, Small Molecule Libraries, Mice, RNA Precursors, Animals, Humans, splice, snRNP, Enhancer, Molecular Biology, Gene, RNA, Double-Stranded, Binding Sites, Protein Stability, Cell Biology, SMA, Survival Analysis, Molecular biology, nervous system diseases, Survival of Motor Neuron 2 Protein, Alternative Splicing, Disease Models, Animal, Proteolysis, RNA splicing, Female, Precursor mRNA, Protein Binding
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16
المؤلفون: Yong Guo, Rajeev Sivasankaran, Zhigang He, Kevin C. Wang, Rachel L. Neve, Jieun Kim, Vuk Koprivica
المصدر: Nature. 417:941-944
مصطلحات موضوعية: Central Nervous System, Nogo Proteins, Receptor complex, Neurite, Glycosylphosphatidylinositols, Growth Cones, Receptors, Cell Surface, Chick Embryo, Biology, GPI-Linked Proteins, Ligands, Retina, Mice, Myelin, Ganglia, Spinal, Nogo Receptor 1, Neurites, medicine, Animals, Humans, Cells, Cultured, Myelin Sheath, Cell Size, Multidisciplinary, Phosphatidylinositol Diacylglycerol-Lyase, Anatomy, Precipitin Tests, Oligodendrocyte, Nerve Regeneration, Cell biology, Myelin-Associated Glycoprotein, Oligodendrocyte-Myelin Glycoprotein, medicine.anatomical_structure, nervous system, Type C Phospholipases, COS Cells, Neuroglia, Cattle, Myelin-Oligodendrocyte Glycoprotein, Cell Division, Myelin Proteins, Protein Binding
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17
المؤلفون: Guglielmo Roma, Natalie Dales, Atwood K. Cheung, Thomas M. Smith, Susanne E. Swalley, Jason R. Thomas, Jeffery A. Porter, Rajeev Sivasankaran, Xiaolu Zhang, Monish Jain, Lei Shu, Leo Murphy, Gregory A. Michaud, Michael Salcius, Mailin Van Hoosear, Caroline Gubser Keller, Mark C. Fishman, Frada Berenshteyn, Cheng Song, William F. Dietrich, Youngah Shin, Caroline Bullock, Brian Tseng, John A. Tallarico, Nicole A. Renaud, Michael McLellan, Sven Schuierer, Vic E. Myer, Donovan N. Chin, Marcel J. J. Blommers, Marc Hild, James Palacino, Martin Beibel, Lin Deng, Arnaud Lacoste, Lawrence G. Hamann, Rebecca Servais, Cecile Blaustein, Daniel Curtis, Xiaoying Shi
المصدر: Nature Chemical Biology. 12:304-304
مصطلحات موضوعية: business.industry, Medicine, Physiology, splice, Cell Biology, Computational biology, business, SMA, Precursor mRNA, Molecular Biology
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18
المؤلفون: Marta Cortes-Cros, Danilo Guerini, Luis M. Craveiro, Maribel Osinde, William Leonard Wishart, Klaus Seuwen, Rajeev Sivasankaran, Martin E. Schwab, Youngah Shin, Florian Mullershausen, Michaela Thallmair, Kumlesh K. Dev, Frederic Bassilana
المصدر: Journal of neurochemistry. 102(4)
مصطلحات موضوعية: Sphingosine-1-phosphate receptor, Inositol Phosphates, Glutamic Acid, Immune receptor, Thiophenes, Biology, Biochemistry, Hippocampus, Cellular and Molecular Neuroscience, Organ Culture Techniques, Cell Movement, Sphingosine, Fingolimod Hydrochloride, Glial Fibrillary Acidic Protein, medicine, Cyclic AMP, Animals, Calcium Signaling, Receptor, Cells, Cultured, G protein-coupled receptor, Cell Proliferation, Cerebral Cortex, Oxadiazoles, Dose-Response Relationship, Drug, Embryo, Mammalian, Cell biology, Rats, Receptors, Lysosphingolipid, medicine.anatomical_structure, Propylene Glycols, Astrocytes, beta-Alanine, Neuroglia, Signal transduction, 2',3'-Cyclic-Nucleotide Phosphodiesterases, Neuroscience, Immunosuppressive Agents, Astrocyte
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19
المؤلفون: Jiong Pei, Yi Ping Zhang, Christopher B. Shields, Xiao Ming Xu, Zhigang He, Rajeev Sivasankaran, Kevin C. Wang
المصدر: Nature neuroscience. 7(3)
مصطلحات موضوعية: Central Nervous System, Nogo Proteins, Neurite, Recombinant Fusion Proteins, Central nervous system, Growth Cones, Biology, Glial scar, Rats, Sprague-Dawley, Myelin, Neural Pathways, medicine, Animals, Protein Isoforms, Axon, Enzyme Inhibitors, Protein kinase C, Cells, Cultured, Protein Kinase C, General Neuroscience, Regeneration (biology), Recovery of Function, Nerve Regeneration, Rats, Repressor Proteins, Myelin-Associated Glycoprotein, medicine.anatomical_structure, Treatment Outcome, nervous system, Chondroitin Sulfate Proteoglycans, Spinal Cord, Female, Neuroscience, Myelin Proteins, Signal Transduction
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20
المؤلفون: Rosalind A. Segal, Jieun Kim, Kevin C. Wang, Zhigang He, Rajeev Sivasankaran
المصدر: Nature. 420(6911)
مصطلحات موضوعية: musculoskeletal diseases, Receptor complex, Nogo Proteins, Co-receptor, Neurite, Receptors, Cell Surface, Chick Embryo, Receptors, Nerve Growth Factor, Biology, GPI-Linked Proteins, Receptor, Nerve Growth Factor, Cell Line, Myelin, Mice, Cricetinae, Ganglia, Spinal, Nogo Receptor 1, Nerve Growth Factor, medicine, Neurites, Animals, Humans, Cells, Cultured, Mice, Knockout, Neurons, Multidisciplinary, Brain-Derived Neurotrophic Factor, Precipitin Tests, biological factors, Transmembrane protein, Cell biology, Protein Structure, Tertiary, Rats, Oligodendrocyte-Myelin Glycoprotein, Myelin-Associated Glycoprotein, medicine.anatomical_structure, nervous system, Biochemistry, Myelin-Oligodendrocyte Glycoprotein, Myelin Proteins, Protein Binding, Signal Transduction