المؤلفون: Javier Poyatos-García, Patricia Soblechero-Martín, Alessandro Liquori, Andrea López-Martínez, Pilar Maestre, Elisa González-Romero, Rafael P. Vázquez-Manrique, Nuria Muelas, Gema García-García, Jessica Ohana, Virginia Arechavala-Gomeza, Juan J. Vílchez

المصدر: Skeletal Muscle, Vol 14, Iss 1, Pp 1-14 (2024)

مصطلحات موضوعية: Duchenne muscular dystrophy, Becker muscular dystrophy, CRISPR-Cas9, Gene therapy, Cell model, Dystrophin, Diseases of the musculoskeletal system, RC925-935

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2044-5040

URL الوصول: https://doaj.org/article/04805daa00ca464381398824273732b2

المؤلفون: David Hervás, Victoria Fornés-Ferrer, Ana Pilar Gómez-Escribano, María Dolores Sequedo, Carmen Peiró, José María Millán, Rafael P Vázquez-Manrique

المصدر: PLoS ONE, Vol 12, Iss 6, p e0179283 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5478119?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/90fd00af281947b99272d6ae6b2f5139

المؤلفون: Denise S Walker, Rafael P Vázquez-Manrique, Nicholas J D Gower, Elizabeth Gregory, William R Schafer, Howard A Baylis

المصدر: PLoS Genetics, Vol 5, Iss 9, p e1000636 (2009)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2729924?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/3ccd8f65aed445bfacfc0e7b03238369

المؤلفون: Rafael P Vázquez-Manrique, Anikó I Nagy, James C Legg, Olivia A M Bales, Sung Ly, Howard A Baylis

المصدر: PLoS Genetics, Vol 4, Iss 3, p e1000043 (2008)

مصطلحات موضوعية: Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC2274882?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

URL الوصول: https://doaj.org/article/2089f5aba5ba4f61bf341fa66eaaca15

المؤلفون: Martina Balducci, Julia Tortajada Pérez, Cristina Trujillo del Río, Mar Collado Pérez, Andrea del Valle Carranza, Ana Pilar Gomez Escribano, Rafael P. Vázquez-Manrique, Andrea Tarozzi

المصدر: International Journal of Molecular Sciences ; Volume 25 ; Issue 22 ; Pages: 12220

مصطلحات موضوعية: erucin, Caenorhabditis elegans, neuroprotection, polyQ toxicity, AMPK, daf-16 /FOXO

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/ijms252212220

الاتاحة: https://doi.org/10.3390/ijms252212220

المؤلفون: Elisa González-Romero, Cristina Martínez-Valiente, Gema García-García, Antonio Rosal-Vela, José María Millán, Miguel Ángel Sanz, Guillermo Sanz, Alessandro Liquori, José Vicente Cervera, Rafael P. Vázquez-Manrique

المصدر: Cancers; Volume 15; Issue 17; Pages: 4263

مصطلحات موضوعية: leukemia, hard-to-transfect cell lines, sgRNA constructs, fusion PCR

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers15174263

الاتاحة: https://doi.org/10.3390/cancers15174263

المؤلفون: Ignasi Mora, Alejandra Pérez-Santamaria, Julia Tortajada-Pérez, Rafael P. Vázquez-Manrique, Lluís Arola, Francesc Puiggròs

المصدر: Cells; Volume 12; Issue 15; Pages: 1932

مصطلحات موضوعية: aging, C. elegans, healthspan, omega-3, PUFA, docosahexaenoic acid, physical decline, structured lipids, DAF-16/FOXO, oxidative stress, antioxidant, nematode, cognitive decline

وصف الملف: application/pdf

Relation: Cellular Aging; https://dx.doi.org/10.3390/cells12151932

الاتاحة: https://doi.org/10.3390/cells12151932

المؤلفون: Javier Poyatos-García, Águeda Blázquez-Bernal, Marta Selva-Giménez, Ariadna Bargiela, Jorge Espinosa-Espinosa, Rafael P. Vázquez-Manrique, Anne Bigot, Ruben Artero, Juan Jesús Vilchez

المصدر: Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 324-338 (2023)

مصطلحات موضوعية: MT: RNA/DNA Editing, LGMDD2, myopathy, cellular model, autophagy, CRISPR, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S2162253123000070; https://doaj.org/toc/2162-2531; https://doaj.org/article/9a5a3e8ee08b4db28d543fbdc27b55f7

الاتاحة: https://doi.org/10.1016/j.omtn.2023.01.004
https://doaj.org/article/9a5a3e8ee08b4db28d543fbdc27b55f7

المؤلفون: Marián Merino, María Dolores Sequedo, Ana Virginia Sánchez-Sánchez, Mª Paz Clares, Enrique García-España, Rafael P. Vázquez-Manrique, José L. Mullor

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 8936

مصطلحات موضوعية: Mn(II) complexes, Huntington’s disease, polyQ toxicity, autophagy, proteasome, Caenorhabditis elegans

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms23168936

الاتاحة: https://doi.org/10.3390/ijms23168936

المؤلفون: Joan Carles Puchalt, Jose F. Gonzalez-Rojo, Ana Pilar Gómez-Escribano, Rafael P. Vázquez-Manrique, Antonio-José Sánchez-Salmerón

المصدر: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1038/s41598-022-05823-6; https://doaj.org/toc/2045-2322; https://doaj.org/article/a3444856d0d346b8a411a2f74aef0cbd

الاتاحة: https://doi.org/10.1038/s41598-022-05823-6
https://doaj.org/article/a3444856d0d346b8a411a2f74aef0cbd

المؤلفون: Marta Vela (11882838), María Adelaida García-Gimeno (11882841), Ana Sanchis (189654), José Bono-Yagüe (11882844), José Cumella (11882847), Laura Lagartera (2867903), Concepción Pérez (1597861), Eva-María Priego (1801138), Angela Campos (7008626), Pascual Sanz (208343), Rafael P. Vázquez-Manrique (11882850), Ana Castro (2060452)

مصطلحات موضوعية: Biochemistry, Genetics, Neuroscience, Biotechnology, Immunology, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, specific structural changes, several neurodegenerative diseases, expanded polyglutamine track, activated protein kinase, using animal models, derived compounds able, cellular level lead, based ampk activator, ind1316 ), confirming, huntington disease aggregation, cellular level, animal models, mice ), huntington disease, vivo results, vivo efficacy, taken together, silico studies, remains unclear, present work, neuroprotective effect, neuropathological symptoms

Relation: https://figshare.com/articles/journal_contribution/Neuroprotective_Effect_of_IND1316_an_Indole-Based_AMPK_Activator_in_Animal_Models_of_Huntington_Disease/17698227

الاتاحة: https://doi.org/10.1021/acschemneuro.1c00758.s001

المؤلفون: Emma Koehorst, Judit Núñez-Manchón, Alfonsina Ballester-López, Miriam Almendrote, Giuseppe Lucente, Andrea Arbex, Jakub Chojnacki, Rafael P. Vázquez-Manrique, Ana Pilar Gómez-Escribano, Guillem Pintos-Morell, Jaume Coll-Cantí, Alba Ramos-Fransi, Alicia Martínez-Piñeiro, Mònica Suelves, Gisela Nogales-Gadea

المصدر: Journal of Clinical Medicine, Vol 10, Iss 5520, p 5520 (2021)

مصطلحات موضوعية: RAN translation, antisense transcription, myotonic dystrophies, primary cell cultures, phenotypic modulators, Medicine

Relation: https://www.mdpi.com/2077-0383/10/23/5520; https://doaj.org/toc/2077-0383; https://doaj.org/article/b68277af270c4aeaafa08277017bb75c

الاتاحة: https://doi.org/10.3390/jcm10235520
https://doaj.org/article/b68277af270c4aeaafa08277017bb75c

المؤلفون: Elisa González-Romero, Cristina Martínez-Valiente, Cristian García-Ruiz, Rafael P. Vázquez-Manrique, José Cervera, Alejandra Sanjuan-Pla

المصدر: Haematologica, Vol 104, Iss 5 (2019)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

Relation: https://haematologica.org/article/view/8891; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

URL الوصول: https://doaj.org/article/02a4545fe77d417db95296ef2230dddd

المؤلفون: Ana P Gómez‐Escribano, Carlos Mora‐Martínez, Marta Roca, Denise S Walker, Joaquín Panadero, Maria D Sequedo, Ratni Saini, Hans‐Joachim Knölker, Jose Blanca, Juan Burguera, Agustin Lahoz, Joaquin Cañizares, José M Millán, Nick O Burton, William R Schafer, Rafael P Vázquez‐Manrique

المصدر: EMBO reports.

مصطلحات موضوعية: Genetics, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d634a17f3724cb506f9d54ec5d881f58
https://doi.org/10.15252/embr.202255556

المؤلفون: Ana Sanchis, María Adelaida García-Gimeno, Antonio José Cañada-Martínez, María Dolores Sequedo, José María Millán, Pascual Sanz, Rafael P. Vázquez-Manrique

المصدر: Experimental and Molecular Medicine, Vol 51, Iss 6, Pp 1-16 (2019)

مصطلحات موضوعية: Medicine, Biochemistry, QD415-436

Relation: https://doi.org/10.1038/s12276-019-0264-9; https://doaj.org/toc/1226-3613; https://doaj.org/toc/2092-6413; https://doaj.org/article/9e189c31709a4e88a36088ef6c27365b

الاتاحة: https://doi.org/10.1038/s12276-019-0264-9
https://doaj.org/article/9e189c31709a4e88a36088ef6c27365b

المؤلفون: Carla Fuster-García, Gema García-García, Elisa González-Romero, Teresa Jaijo, María D. Sequedo, Carmen Ayuso, Rafael P. Vázquez-Manrique, José M. Millán, Elena Aller

المصدر: Molecular Therapy: Nucleic Acids, Vol 8, Iss , Pp 529-541 (2017)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S2162253117302299; https://doaj.org/toc/2162-2531; https://doaj.org/article/f43fca243fef4f4a9973a953b7c526c3

الاتاحة: https://doi.org/10.1016/j.omtn.2017.08.003
https://doaj.org/article/f43fca243fef4f4a9973a953b7c526c3

المؤلفون: Marta Vela, María Adelaida García-Gimeno, Ana Sanchis, José Bono-Yagüe, José Cumella, Laura Lagartera, Concepción Pérez, Eva-María Priego, Angela Campos, Pascual Sanz, Rafael P. Vázquez-Manrique, Ana Castro

المساهمون: National Institutes of Health (US), Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades (España), Fundació La Marató de TV3, European Commission, Fundación Ramón Areces, Generalitat Valenciana, Real e Ilustre Colegio de Farmacéuticos de Sevilla, Fundación Cajasol, Asociación Valenciana de Enfermedad de Huntington, Sanz, Pascual, Sanz, Pascual [0000-0002-2399-4103]

المصدر: ACS Chem Neurosci
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: AMPK, Huntingtin Protein, Huntington disease mouse models, Indoles, Physiology, Cognitive Neuroscience, C. elegans models, Cell Biology, General Medicine, AMP-Activated Protein Kinases, Biochemistry, polyQ toxicity, Neuroprotection, Article, Disease Models, Animal, Mice, Huntington Disease, Neuroprotective Agents, Animals, Indole derivatives, ADME in silico

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5944d12417567ba5b490dcf8a56de4f
https://pubmed.ncbi.nlm.nih.gov/34962383

المؤلفون: José Cervera, Rafael P. Vázquez-Manrique, C Martínez-Valiente, A Rosal-Vela, E González-Romero, G García-García, A Liquori, MA Sanz, José M. Millán

مصطلحات موضوعية: Mutation, Haematopoiesis, Myeloid, medicine.anatomical_structure, Cas9, HEK 293 cells, medicine, CRISPR, Computational biology, Transfection, Biology, medicine.disease_cause, Viral vector

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b4ff8dd4b4945f287e690fbefc15cf4b
https://doi.org/10.1101/2021.10.25.465699

المؤلفون: David, Brinvillier, Melissa, Barrast, Petra, Couderc-Murillo, José, Bono-Yagüe, Alain, Rousteau, Ana Pilar, Gómez Escribano, Marcos V, Palmeira-Mello, Antonio, Doménech-Carbó, Nady, Passe-Coutrin, Muriel, Sylvestre, Rafael P, Vázquez-Manrique, Gerardo, Cebrián-Torrejón

المصدر: ACS omega. 7(19)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::01bbff8fa41ba95731a37e6106225057
https://pubmed.ncbi.nlm.nih.gov/35601340

المؤلفون: Cendrine Tourette, Francesca Farina, Rafael P Vazquez-Manrique, Anne-Marie Orfila, Jessica Voisin, Sonia Hernandez, Nicolas Offner, J Alex Parker, Sophie Menet, Jinho Kim, Jungmok Lyu, Si Ho Choi, Kerry Cormier, Christina K Edgerly, Olivia L Bordiuk, Karen Smith, Anne Louise, Michael Halford, Steven Stacker, Jean-Philippe Vert, Robert J Ferrante, Wange Lu, Christian Neri

المصدر: PLoS Biology, Vol 12, Iss 6, p e1001895 (2014)

مصطلحات موضوعية: Biology (General), QH301-705.5

Relation: http://europepmc.org/articles/PMC4068980?pdf=render; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885; https://doaj.org/article/30fe5f15c42b4abcbb453493275b5e19

الاتاحة: https://doi.org/10.1371/journal.pbio.1001895
https://doaj.org/article/30fe5f15c42b4abcbb453493275b5e19