المؤلفون: Weckman, M. J., Karikoski, N. P., Raekallio, M. R., Box, J. R., Kvist, L.

المساهمون: Equine and Small Animal Medicine, Departments of Faculty of Veterinary Medicine, Helsinki One Health (HOH), Teachers' Academy, DAPHNE - Developing Assessment Practices in Higher Education, Marja Raekallio / Principal Investigator

مصطلحات موضوعية: Equine genome, Genome-wide association study, Insulin dysregulation, Single-nucleotide polymorphism, Veterinary science

وصف الملف: application/pdf

Relation: The authors thank the Finnish Foundation of Veterinary Research (Finland) for funding the genome-wide association analysis in this study. In addition, the Erkki Rajakoski Foundation (Suomen Hippos, Finland) is thanked for a grant. The authors thank the Finnish Foundation of Veterinary Research (Finland) for funding the genome-wide association analysis in this study. In addition, the Erkki Rajakoski Foundation (Suomen Hippos, Finland) is thanked for a grant.; Weckman , M J , Karikoski , N P , Raekallio , M R , Box , J R & Kvist , L 2024 , ' Genome-wide association study suggests genetic candidate loci of insulin dysregulation in Finnhorses ' , Veterinary Journal , vol. 303 , 106063 . https://doi.org/10.1016/j.tvjl.2024.106063; ORCID: /0000-0002-6163-925X/work/153474028; http://hdl.handle.net/10138/571229; 416780aa-c9f4-490b-bcde-79f547bbbf06; 85183518625

الاتاحة: http://hdl.handle.net/10138/571229

المؤلفون: Immonen, H., Raekallio, M. R., Holmström, A-R.

المساهمون: Faculty of Pharmacy, Helsinki One Health (HOH), DAPHNE - Developing Assessment Practices in Higher Education, Teachers' Academy, Marja Raekallio / Principal Investigator, Equine and Small Animal Medicine, Departments of Faculty of Veterinary Medicine, Drug Research Program, Division of Pharmacology and Pharmacotherapy

مصطلحات موضوعية: Competence, Inter-professional, Medication safety, Pharmacy, Survey, Veterinary pharmacotherapy, Veterinary science

وصف الملف: application/pdf

Relation: Open access funded by Helsinki University Library. This research did not receive any other specific grant from funding agencies in the public, commercial, or not-for-profit sectors.; Immonen , H , Raekallio , M R & Holmström , A-R 2023 , ' Promoting veterinary medication safety - Exploring the competencies of community pharmacy professionals in veterinary pharmacotherapy ' , Veterinary and Animal Science , vol. 21 . https://doi.org/10.1016/j.vas.2023.100310; ORCID: /0000-0002-3908-5430/work/152924629; http://hdl.handle.net/10138/570858; 77d42b1c-1a93-4a7f-aafc-948921f8d898; 001067913400001

الاتاحة: http://hdl.handle.net/10138/570858

المؤلفون: Hallman, I. A. M., Raekallio, M. R., Koho, N., Weckman, M. J., Karikoski, N. P.

المساهمون: Equine and Small Animal Medicine, Faculty of Veterinary Medicine, Departments of Faculty of Veterinary Medicine, Helsinki One Health (HOH), Teachers' Academy, DAPHNE - Developing Assessment Practices in Higher Education, Marja Raekallio / Principal Investigator, Veterinary Teaching Hospital, Equine Hospital

مصطلحات موضوعية: Alpha-2-adrenoceptor, Detomidine, Glucose, Insulin, Vatinoxan, Veterinary science

وصف الملف: application/pdf

Relation: This study was supported by Vetcare Finland Oy (by providing the medication: detomidine HCl and vatinoxan HCl), the Finnish Veterinary Foundation (grant funding), the Finnish Foundation of Veterinary Research (grant funding), and the Erkki Rajakoski Foundation (grant funding). Preliminary results were presented as a poster at the Nordic Equine Veterinary Conference, Tampere, Finland, 4–6 March 2022 and as an oral presentation at the Finnish Veterinary Congress, Helsinki, Finland, 2–4 November 2022.; Hallman , I A M , Raekallio , M R , Koho , N , Weckman , M J & Karikoski , N P 2024 , ' Effects of alpha-2-adrenoceptor agonism and antagonism on equine blood insulin and glucose concentrations after oral carbohydrate load ' , Veterinary Journal , vol. 304 , 106080 . https://doi.org/10.1016/j.tvjl.2024.106080; ORCID: /0000-0002-6163-925X/work/156152458; http://hdl.handle.net/10138/573436; a883a369-ae91-416e-bcdb-aeab7b9a9db0; 85185836856

الاتاحة: http://hdl.handle.net/10138/573436

المؤلفون: Box, J. R., Karikoski, N. P., Tanskanen, H. E., Raekallio, M. R.

المساهمون: Equine and Small Animal Medicine, Faculty of Veterinary Medicine, Equine Hospital, University Management, DAPHNE - Developing Assessment Practices in Higher Education, Helsinki One Health (HOH), Marja Raekallio / Principal Investigator, Teachers' Academy

مصطلحات موضوعية: Equine, Detomidine, Insulin dysregulation, Sedation, Vatinoxan, Veterinary science

وصف الملف: application/pdf

Relation: Preliminary results were presented as an oral presentation at the 4th Global Equine Endocrinology Symposium, Chieming, Germany, 6-10 January 2020. The authors would like to thank Vetcare for providing funding for this study. We also wish to thank Ninna Koho for her analysis of glucagon samples.; Box , J R , Karikoski , N P , Tanskanen , H E & Raekallio , M R 2021 , ' The effects of an alpha-2-adrenoceptor agonist, antagonist, and their combination on the blood insulin, glucose, and glucagon concentrations in insulin sensitive and dysregulated horses ' , Veterinary Journal , vol. 269 , 105610 . https://doi.org/10.1016/j.tvjl.2021.105610; http://hdl.handle.net/10138/328940; 338b8610-2435-4382-b22e-d1687530820e; 000626149100007

الاتاحة: http://hdl.handle.net/10138/328940

المؤلفون: Tapio, H., Raekallio, M. R., Mykkänen, A., Männikkö, S., Scheinin, M., Bennett, R. C., Vainio, O.

المساهمون: Equine and Small Animal Medicine, Faculty of Veterinary Medicine, Helsinki One Health (HOH), DAPHNE - Developing Assessment Practices in Higher Education, Marja Raekallio / Principal Investigator, Outi Vainio / Principal Investigator, Research Centre for Animal Welfare, Teachers' Academy

مصطلحات موضوعية: horse, sedation, medetomidine, vatinoxan, MK-467, alpha(2)-antagonist, ALPHA(2)-ADRENOCEPTOR ANTAGONIST, INTRAVENOUS DEXMEDETOMIDINE, DETOMIDINE, PHARMACOKINETICS, ROMIFIDINE, XYLAZINE, AGONISTS, DRUGS, Veterinary science

وصف الملف: application/pdf

Relation: Financial support was provided by Vetcare Ltd. (Mantsala, Finland) for the study expenses; materials and drugs.; Tapio , H , Raekallio , M R , Mykkänen , A , Männikkö , S , Scheinin , M , Bennett , R C & Vainio , O 2019 , ' Effects of vatinoxan on cardiorespiratory function and gastrointestinal motility during constant-rate medetomidine infusion in standing horses ' , Equine Veterinary Journal , vol. 51 , no. 5 , pp. 646-652 . https://doi.org/10.1111/evj.13085; ORCID: /0000-0003-4248-8983/work/60609271; ORCID: /0000-0003-3467-2246/work/60611410; http://hdl.handle.net/10138/304658; 04425adc-6999-4121-866e-dd71e2fd73e0; 000478608500015

الاتاحة: http://hdl.handle.net/10138/304658

المؤلفون: Kallio-Kujala, I. J., Turunen, H. A., Raekallio, M. R., Honkavaara, J. M., Salla, K. M., Casoni, D., Hautajarvi, H. J., Vainio, O. M.

المساهمون: Equine and Small Animal Medicine, Financial and Macroeconometrics, Marja Raekallio / Principal Investigator, Outi Vainio / Principal Investigator, Research Centre for Animal Welfare, DAPHNE - Developing Assessment Practices in Higher Education, Teachers' Academy

مصطلحات موضوعية: Anaesthesia, Butorphanol, Canine, Medetomidine, MK-467, ALPHA(2)-ADRENERGIC RECEPTOR ANTAGONIST, CONSCIOUS DOGS, ALPHA-2-ADRENOCEPTOR ANTAGONIST, INTRAVENOUS DEXMEDETOMIDINE, L-659,066, VARIABLES, SEDATION, INDEX, Veterinary science

وصف الملف: application/pdf

Relation: Vetcare, which produces MK-467, provided funding for the materials and medications used in this study. Results of this study were presented as an abstract at the Association of Veterinary Anesthetists Autumn Meeting, Berlin, Germany, 9-11 November 2017, and the Annual Veterinary Congress, Helsinki, Finland, 13-15 December 2017.; Kallio-Kujala , I J , Turunen , H A , Raekallio , M R , Honkavaara , J M , Salla , K M , Casoni , D , Hautajarvi , H J & Vainio , O M 2018 , ' Peripherally acting alpha-adrenoceptor antagonist MK-467 with intramuscular medetomidine and butorphanol in dogs : A prospective, randomised, clinical trial ' , Veterinary Journal , vol. 240 , pp. 22-26 . https://doi.org/10.1016/j.tvjl.2018.08.007; ORCID: /0000-0003-3467-2246/work/54789609; ORCID: /0000-0003-2203-6699/work/54791793; ORCID: /0000-0002-8045-3549/work/141598260; http://hdl.handle.net/10138/299961; 16650146-d5ae-4f00-b2b6-80891d536c46; 85052944557; 000447478000005

الاتاحة: http://hdl.handle.net/10138/299961

المؤلفون: Tapio, H. A., Raekallio, M. R., Mykkänen, A. K., Al-Ramahi, D., Scheinin, M., Hautajarvi, H. J., Männikkö, S., Vainio, O.

المساهمون: Equine and Small Animal Medicine, Faculty of Veterinary Medicine, Helsinki One Health (HOH), DAPHNE - Developing Assessment Practices in Higher Education, Marja Raekallio / Principal Investigator, University Management, Staff Services, Outi Vainio / Principal Investigator, Research Centre for Animal Welfare, Teachers' Academy

مصطلحات موضوعية: Anesthesia, Cardiovascular function, Horse, Medetomidine, Vatinoxan, CONSTANT RATE INFUSION, PERIPHERAL ALPHA-2-ADRENOCEPTOR ANTAGONIST, INTRAVENOUS DEXMEDETOMIDINE, ALPHA(2)-ADRENOCEPTOR ANTAGONIST, MK-467, DETOMIDINE, ROMIFIDINE, HALOTHANE, XYLAZINE, Veterinary science

وصف الملف: application/pdf

Relation: Financial support was provided by Vetcare Ltd. (Mantsala, Finland) for the study expenses; materials and drugs. Vetcare Ltd. did not have any involvement in the study design, data analysis and interpretation, or writing and publication of the manuscript. None of the authors has any other financial or personal relationships that could inappropriately influence or bias the content of the paper.; Tapio , H A , Raekallio , M R , Mykkänen , A K , Al-Ramahi , D , Scheinin , M , Hautajarvi , H J , Männikkö , S & Vainio , O 2019 , ' Effects of vatinoxan on cardiorespiratory function, fecal output and plasma drug concentrations in horses anesthetized with isoflurane and infusion of medetomidine ' , Veterinary Journal , vol. 251 , 105345 . https://doi.org/10.1016/j.tvjl.2019.105345; ORCID: /0000-0003-4248-8983/work/63999393; ORCID: /0000-0003-3467-2246/work/64000006; http://hdl.handle.net/10138/306500; d82e88c2-3232-42a9-bf0d-5411dd41a0a1; 000488137200007

الاتاحة: http://hdl.handle.net/10138/306500

المؤلفون: Kallio-Kujala, I. J., Bennett, R. C., Raekallio, M. R., Yatkin, E., Meierjohann, A., Savontaus, E., Scheinin, M., Spillmann, T., Vainio, O. M.

المساهمون: Small Animal Hospital, Equine and Small Animal Medicine, Faculty of Veterinary Medicine, Marja Raekallio / Principal Investigator, Thomas Spillmann / Principal Investigator, Outi Vainio / Principal Investigator, Research Centre for Animal Welfare, DAPHNE - Developing Assessment Practices in Higher Education, Teachers' Academy

مصطلحات موضوعية: Canine, Dexmedetomidine, Glibenclamide, Hypoglycaemia, MK-467, ALPHA(2)-ADRENERGIC RECEPTOR ANTAGONIST, INTRAVENOUS DEXMEDETOMIDINE, MEDETOMIDINE, PHARMACOKINETICS, CARDIOPULMONARY, SECRETION, LACTATE, DOG, Veterinary science

وصف الملف: application/pdf

Relation: Vetcare funded this study. Preliminary results were presented as an abstract at the 12th World Congress of Veterinary Anesthesiology, Kyoto, Japan, 4th-9th September 2015.; Kallio-Kujala , I J , Bennett , R C , Raekallio , M R , Yatkin , E , Meierjohann , A , Savontaus , E , Scheinin , M , Spillmann , T & Vainio , O M 2018 , ' Effects of dexmedetomidine and MK-467 on plasma glucose, insulin and glucagon in a glibenclamide-induced canine hypoglycaemia model ' , Veterinary Journal , vol. 242 , pp. 33-38 . https://doi.org/10.1016/j.tvjl.2018.09.012; ORCID: /0000-0003-3467-2246/work/52862307; ORCID: /0000-0003-2203-6699/work/52866077; ORCID: /0000-0002-0176-7428/work/160333943; http://hdl.handle.net/10138/294741; 766dfe29-668d-403b-befa-3f44ad47cb71; 85055273811; 000452814500005

الاتاحة: http://hdl.handle.net/10138/294741

المؤلفون: Adam, M., Raekallio, M. R., Keskitalo, T., Honkavaara, J. M., Scheinin, M., Kajula, M., Mölsä, S., Vainio, O. M.

المساهمون: Departments of Faculty of Veterinary Medicine, Equine and Small Animal Medicine, Faculty of Veterinary Medicine, Marja Raekallio / Principal Investigator, Outi Vainio / Principal Investigator, Research Centre for Animal Welfare, DAPHNE - Developing Assessment Practices in Higher Education, Teachers' Academy, Softis - pehmytkudossairaudet, Petbone – ortopedia, fysioterapia, kivunlievitys

مصطلحات موضوعية: atipamezole, medetomidine, MK-467, sheep, PERIPHERAL ALPHA(2)-ADRENOCEPTOR ANTAGONIST, CONSCIOUS DOGS, INTRAVENOUS DEXMEDETOMIDINE, RECEPTOR ANTAGONIST, PHARMACOKINETICS, AGONIST, DETOMIDINE, YOHIMBINE, XYLAZINE, BLOOD, Veterinary science

وصف الملف: application/pdf

Relation: Vetcare Ltd., Finland; Adam , M , Raekallio , M R , Keskitalo , T , Honkavaara , J M , Scheinin , M , Kajula , M , Mölsä , S & Vainio , O M 2018 , ' The impact of MK-467 on plasma drug concentrations, sedation and cardiopulmonary changes in sheep treated with intramuscular medetomidine and atipamezole for reversal ' , Journal of Veterinary Pharmacology and Therapeutics , vol. 41 , no. 3 , pp. 447-456 . https://doi.org/10.1111/jvp.12486; ORCID: /0000-0003-3467-2246/work/45241144; ORCID: /0000-0002-2473-5912/work/45241690; ORCID: /0000-0003-2484-1157/work/121696861; ORCID: /0000-0002-8045-3549/work/141598294; http://hdl.handle.net/10138/235377; af2a9d65-41ac-4872-b8d4-6f108b47859e; 85040712197; 000431503200013

الاتاحة: http://hdl.handle.net/10138/235377

المؤلفون: Niinistö, K. E., Ruohoniemi, M. O., Freccero, F., Raekallio, M. R.

المساهمون: Niinistö, K.E., Ruohoniemi, M.O., Freccero, F., Raekallio, M.R.

مصطلحات موضوعية: Equine, Geosediment, Nasogastric tubing, Plantago ovata, Sand

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000444359700004; volume:238; firstpage:22; lastpage:26; numberofpages:5; journal:THE VETERINARY JOURNAL; http://hdl.handle.net/11585/636256; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85048855351; https://www.sciencedirect.com/science/article/pii/S1090023318302648?via=ihub

الاتاحة: http://hdl.handle.net/11585/636256
https://doi.org/10.1016/j.tvjl.2018.06.005
https://www.sciencedirect.com/science/article/pii/S1090023318302648?via=ihub

المؤلفون: Adam, M, Huuskonen, V, Raekallio, M R, Casoni, Daniela, Mykkänen, A K, Lappalainen, A K, Kajula, M, Kallio-Kujala, I J, Vainio, O M

المصدر: Adam, M; Huuskonen, V; Raekallio, M R; Casoni, Daniela; Mykkänen, A K; Lappalainen, A K; Kajula, M; Kallio-Kujala, I J; Vainio, O M (2018). Cardiopulmonary effects of vatinoxan in sevoflurane-anaesthetised sheep receiving dexmedetomidine. Veterinary journal, 238, pp. 63-69. Elsevier 10.1016/j.tvjl.2018.07.007

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/124472/

الاتاحة: https://boris.unibe.ch/124472/2/1-s2.0-S1090023318303873-main.pdf
https://boris.unibe.ch/124472/

المؤلفون: Kallio-Kujala, I J, Turunen, H A, Raekallio, M R, Honkavaara, J M, Salla, K M, Casoni, Daniela, Hautajärvi, H J, Vainio, O M

المصدر: Kallio-Kujala, I J; Turunen, H A; Raekallio, M R; Honkavaara, J M; Salla, K M; Casoni, Daniela; Hautajärvi, H J; Vainio, O M (2018). Peripherally acting α-adrenoceptor antagonist MK-467 with intramuscular medetomidine and butorphanol in dogs: A prospective, randomised, clinical trial. Veterinary journal, 240, pp. 22-26. Elsevier 10.1016/j.tvjl.2018.08.007

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/124480/

الاتاحة: https://boris.unibe.ch/124480/2/1-s2.0-S1090023318304805-main.pdf
https://boris.unibe.ch/124480/

المؤلفون: Bennett, R. C., Salla, K. M., Raekallio, M. R., Hänninen, L., Rinne, V. M., Scheinin, M., Vainio, O. M.

المساهمون: Eläinlääketieteen Tutkimuksen Tukisäätiö

المصدر: Journal of Veterinary Pharmacology and Therapeutics ; volume 39, issue 4, page 336-343 ; ISSN 0140-7783 1365-2885

الاتاحة: http://dx.doi.org/10.1111/jvp.12292
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjvp.12292
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jvp.12292

المؤلفون: Bennett, R. C., Hokkanen, J., Raekallio, M. R., Vainio, O. M.

المساهمون: Vetcare Ltd, ANIWEL graduate school, University of Helsinki, Finland

المصدر: Journal of Veterinary Pharmacology and Therapeutics ; volume 39, issue 4, page 405-407 ; ISSN 0140-7783 1365-2885

الاتاحة: http://dx.doi.org/10.1111/jvp.12291
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjvp.12291
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jvp.12291

المؤلفون: HONKAVAARA, J. M., RESTITUTTI, F., RAEKALLIO, M. R., KUUSELA, E. K., VAINIO, O. M.

المصدر: Journal of Veterinary Pharmacology and Therapeutics ; volume 34, issue 4, page 332-337 ; ISSN 0140-7783 1365-2885

الاتاحة: http://dx.doi.org/10.1111/j.1365-2885.2010.01242.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2885.2010.01242.x
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2885.2010.01242.x

المؤلفون: RAEKALLIO, M. R., HONKAVAARA, J. M., VAINIO, O. M.

المصدر: Journal of Veterinary Pharmacology and Therapeutics ; volume 33, issue 5, page 434-438 ; ISSN 0140-7783 1365-2885

الاتاحة: http://dx.doi.org/10.1111/j.1365-2885.2009.01156.x
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2885.2009.01156.x
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2885.2009.01156.x

المؤلفون: Honkavaara, J. M., Restitutti, F., Raekallio, M. R., Kuusela, E. K., Vainio, O. M.

المصدر: Journal of Veterinary Pharmacology & Therapeutics; Aug2011, Vol. 34 Issue 4, p332-337, 6p, 1 Chart, 6 Graphs

مصطلحات موضوعية: HEMODYNAMICS, BLOOD gases analysis, HEART beat, PHYSIOLOGICAL transport of oxygen, VASCULAR resistance, ADRENERGIC receptors, LABORATORY dogs

المؤلفون: Raekallio, M. R., Honkavaara, J. M., Vainio, O. M.

المصدر: Journal of Veterinary Pharmacology & Therapeutics; Oct2010, Vol. 33 Issue 5, p434-438, 5p, 5 Graphs

مصطلحات موضوعية: SHEEP, ADRENERGIC receptors, VERAPAMIL, HEMODYNAMICS, CENTRAL venous pressure, VASCULAR resistance, CARDIAC output

المؤلفون: Hokkanen, A.-H., Raekallio, M. R., Salla, K., Hänninen, L., Viitasaari, E., Norring, M., Raussi, Satu, Rinne, V. M., Scheinin, M., Vainio, O. M.

المساهمون: University of Helsinki, University of Turku, Turku University Hospital

مصطلحات موضوعية: calves, detomidine, disbudding, welfare, neurotropic drugs, oromucosal

وصف الملف: Sekä painettu, että verkkojulkaisu; 372-377; true

Relation: Veterinary Anaesthesia and Analgesia; 41; http://jukuri.luke.fi/handle/10024/538688; URN:NBN:fi-fe201706207400

الاتاحة: http://jukuri.luke.fi/handle/10024/538688

المؤلفون: Salla, K. M., Restitutti, F., Vainionpää, M. H., Raekallio, M. R., Honkavaara, J., Kuusela, E. K., Outi Maritta Vainio

المصدر: University of Helsinki

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::440fdfc5f80cffc60b328324ed10dd34
https://tuhat.helsinki.fi/portal/en/publications/the-cardiopulmonary-effects-of-a-peripheral-alpha2adrenoceptor-antagonist-mk467-in-dogs-sedated-with-medetomidine-and-butorhanol(0f3e3048-ef18-4e68-9d57-a8be260476e0).html