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1Academic Journal
المؤلفون: Vincent Sauzeau, Julien Beignet, Christian Bailly
المصدر: Biomedicines; Volume 10; Issue 6; Pages: 1357
مصطلحات موضوعية: bladder cancer, Rho GTPase, bladder dysfunction, Rac inhibitors, metastasis, overactive bladder, Rac1 protein
وصف الملف: application/pdf
Relation: Cancer Biology and Therapeutics; https://dx.doi.org/10.3390/biomedicines10061357
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2Academic Journal
المؤلفون: Acosta, M.I, Urbach, S, Doye, A, Ng, Y.-W, Boudeau, J, Mettouchi, A, Debant, A, Manser, E, Visvikis, O, Lemichez, E
المساهمون: DEPT OF PHARMACOLOGY
المصدر: Unpaywall 20201031
مصطلحات موضوعية: bacterial toxin, cytotoxic necrotizing factor 1, Escherichia coli protein, HACE1 protein, human, p21 activated kinase, Rac1 protein, serine, ubiquitin protein ligase, vasculotropin A, cell line, chemistry, metabolism, phosphorylation, protein multimerization, proteomics, ubiquitination, umbilical vein endothelial cell, Bacterial Toxins, Escherichia coli Proteins, Human Umbilical Vein Endothelial Cells, Humans, p21-Activated Kinases, rac1 GTP-Binding Protein, Ubiquitin-Protein Ligases, Vascular Endothelial Growth Factor A
Relation: Acosta, M.I, Urbach, S, Doye, A, Ng, Y.-W, Boudeau, J, Mettouchi, A, Debant, A, Manser, E, Visvikis, O, Lemichez, E (2018). Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination. Scientific Reports 8 (1) : 1410. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-018-19471-2; https://scholarbank.nus.edu.sg/handle/10635/178469
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3Academic Journal
المؤلفون: Nie, T, Hui, X, Mao, L, Nie, B, Li, K, Sun, W, Gao, X, Tang, X, Xu, Y, Jiang, B, Tu, Z, Li, P, Ding, K, Han, W, Zhang, S, Xu, A, Ding, S, Liu, P, Patterson, A, Cooper, G, Wu, D
المساهمون: DUKE-NUS MEDICAL SCHOOL
المصدر: Unpaywall 20201031
مصطلحات موضوعية: DNA helicase, harmine, Mi-2beta protein, mouse, neuropeptide, Rac1 protein, adipocyte, animal, brown adipocyte, cell culture, cytology, drug effect, energy metabolism, genetics, lipid diet, MAPK signaling, metabolism, thermogenesis, white adipocyte, Adipocytes, Brown, White, Animals, Cells, Cultured, Diet, High-Fat, DNA Helicases, MAP Kinase Signaling System, Mice
Relation: Nie, T, Hui, X, Mao, L, Nie, B, Li, K, Sun, W, Gao, X, Tang, X, Xu, Y, Jiang, B, Tu, Z, Li, P, Ding, K, Han, W, Zhang, S, Xu, A, Ding, S, Liu, P, Patterson, A, Cooper, G, Wu, D (2016). Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis. Scientific Reports 6 : 36382. ScholarBank@NUS Repository. https://doi.org/10.1038/srep36382; https://scholarbank.nus.edu.sg/handle/10635/179790
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4Academic Journal
المؤلفون: Wang, J, Liu, M, Chen, L, Chan, T.H.M, Jiang, L, Yuan, Y.-F, Guan, X.-Y
المساهمون: ANATOMY, CANCER SCIENCE INSTITUTE OF SINGAPORE
المصدر: Unpaywall 20201031
مصطلحات موضوعية: agar, cyclin D1, dynamin II, F actin, guanosine triphosphatase, n terminal kinase like protein, protein, protein Cdc42, protein p53, Rac1 protein, unclassified drug, CHD1L protein, human, DNA binding protein, DNA helicase, DNM2 protein, dynamin, SCYL1 protein, transcription factor, adult, amino terminal kinase like gene, animal cell, animal experiment, animal model, animal tissue, apoptosis, Article, cancer prognosis, carcinogenesis, carcinogenicity
Relation: Wang, J, Liu, M, Chen, L, Chan, T.H.M, Jiang, L, Yuan, Y.-F, Guan, X.-Y (2015). Overexpression of N-terminal kinase like gene promotes tumorigenicity of hepatocellular carcinoma by regulating cell cycle progression and cell motility. Oncotarget 6 (3) : 1618-1630. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.2730; https://scholarbank.nus.edu.sg/handle/10635/180963
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5Academic Journal
المصدر: Frontiers in Systems Neuroscience, Vol 8 (2014)
مصطلحات موضوعية: excitation-inhibition balance, layer II cortex, field recordings, Golgi-Cox staining, Rac1 protein, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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6Academic Journal
المؤلفون: Liu, J, Pasini, S, Shelanski, M.L, Greene, L.A
المساهمون: PATHOLOGY
المصدر: Unpaywall 20201031
مصطلحات موضوعية: activating transcription factor 4, guanosine triphosphate, postsynaptic density protein 95, protein Cdc42, Rac1 protein, short hairpin RNA, adult, animal cell, animal tissue, article, cell density, cell structure, confocal microscopy, controlled study, dendritic spine, down regulation, embryo, hippocampus, human, human cell, immunocytochemistry, immunohistochemistry, Lentivirinae, male, mouse, mushroom, nonhuman, postsynaptic membrane, protein expression, protein metabolism
Relation: Liu, J, Pasini, S, Shelanski, M.L, Greene, L.A (2014). Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology. Frontiers in Cellular Neuroscience 8 (JUN) : 177. ScholarBank@NUS Repository. https://doi.org/10.3389/fncel.2014.00177; https://scholarbank.nus.edu.sg/handle/10635/181495
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7Academic Journal
المؤلفون: Tong, L, Tergaonkar, V
المساهمون: PATHOLOGY, DUKE-NUS MEDICAL SCHOOL
المصدر: Unpaywall 20201031
مصطلحات موضوعية: cytokine, guanosine nucleotide dissociation inhibitor, I kappa B alpha, immunoglobulin enhancer binding protein, integrin, protein Cdc42, protein p120, Rac protein, Rac1 protein, Rho factor, Rho guanine nucleotide binding protein, Rho guanine nucleotide exchange factor, RhoA guanine nucleotide binding protein, transcription factor RelA, tumor necrosis factor alpha, unclassified drug, human, RHOA protein, article, binding affinity, cell adhesion, extracellular matrix, immunoregulation, inflammation, molecular pathology, nonhuman, protein binding, protein degradation, protein domain, protein expression
Relation: Tong, L, Tergaonkar, V (2014). Rho protein GTPases and their interactions with NF?B: Crossroads of inflammation and matrix biology. Bioscience Reports 34 (3) : 283-295. ScholarBank@NUS Repository. https://doi.org/10.1042/BSR20140021; https://scholarbank.nus.edu.sg/handle/10635/180179
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8Academic Journal
المؤلفون: Jacobs, Valerie L, Liu, Yingna, De Leo, Joyce A
المصدر: Dartmouth Scholarship
مصطلحات موضوعية: animals, blotting, western, cell movement, flow cytometry, focal adhesion kinase 2, glioblastoma, immunohistochemistry, microglia, neuropeptides, rna interference, rna, small interfering, rats, tumor necrosis factor, signal transduction, xanthines, rac gtp-binding proteins, rac1 gtp-binding protein, rac1 protein, receptors, tnfrsf19 protein, mouse, propentofylline, ptk2b protein, rac gtp-binding prot, Medicine and Health Sciences
وصف الملف: application/pdf
Relation: https://digitalcommons.dartmouth.edu/facoa/3128; https://digitalcommons.dartmouth.edu/context/facoa/article/4117/viewcontent/ptpmcrender.fcgi
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9Academic Journal
المساهمون: DEPT OF PHARMACOLOGY
المصدر: Unpaywall 20201031
مصطلحات موضوعية: phosphatase, phosphatase POPX2, protein Cdc42, protein mDia1, Rac1 protein, Rho guanine nucleotide binding protein, RhoA guanine nucleotide binding protein, serum response factor, transcription factor, unclassified drug, actin polymerization, article, cell adhesion, cell motility, controlled study, cytoskeleton, human, human cell, priority journal, protein analysis, protein binding, protein function, protein protein interaction, serum responsive element, stress fiber, transcription regulation, Animals, Biological Transport, Carrier Proteins, Immunoprecipitation
Relation: Xie, Y, Tan, E.-J, Wee, S, Manser, E, Lim, L, Koh, C.-G (2008). Functional interactions between phosphatase POPX2 and mDia modulate RhoA pathways. Journal of Cell Science 121 (4) : 514-521. ScholarBank@NUS Repository. https://doi.org/10.1242/jcs.013557; https://scholarbank.nus.edu.sg/handle/10635/181025
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10Academic Journal
المؤلفون: Matteucci A., Ricceri L., Fabbri A., Fortuna A., Travaglione S., Guidotti M., Martinelli A., Villa M., Pricci F., Maroccia Z., Campana G., Malchiodi-Albedi F., Fiorentini C., Loizzo S.
المساهمون: Matteucci A., Ricceri L., Fabbri A., Fortuna A., Travaglione S., Guidotti M., Martinelli A., Villa M., Pricci F., Maroccia Z., Campana G., Malchiodi-Albedi F., Fiorentini C., Loizzo S.
مصطلحات موضوعية: cytotoxic necrotizing factor 1, gliosi, hypertensive retinopathy, ophthalmic solution, Rac1 protein, spontaneously hypertensive rats
وصف الملف: ELETTRONICO
Relation: info:eu-repo/semantics/altIdentifier/pmid/31128161; info:eu-repo/semantics/altIdentifier/wos/WOS:000473586500010; volume:411; firstpage:119; lastpage:129; numberofpages:11; journal:NEUROSCIENCE; http://hdl.handle.net/11585/713299; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85066925575; www.elsevier.com/locate/neuroscience
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11
المؤلفون: Gabriele Campana, Alessia Fabbri, Sara Travaglione, Stefano Loizzo, Marika Villa, Zaira Maroccia, Andrea Martinelli, Flavia Pricci, Fiorella Malchiodi-Albedi, Laura Ricceri, Carla Fiorentini, Andrea Fortuna, Marco Guidotti, Andrea Matteucci
المساهمون: Matteucci A., Ricceri L., Fabbri A., Fortuna A., Travaglione S., Guidotti M., Martinelli A., Villa M., Pricci F., Maroccia Z., Campana G., Malchiodi-Albedi F., Fiorentini C., Loizzo S.
المصدر: Neuroscience. 411
مصطلحات موضوعية: 0301 basic medicine, Male, Central nervous system, Bacterial Toxins, Inflammation, Hypertensive Retinopathy, Pharmacology, Retina, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Hypertensive retinopathy, Rats, Inbred SHR, medicine, gliosi, Animals, Gliosis, Vision, Ocular, Glial fibrillary acidic protein, biology, business.industry, General Neuroscience, Escherichia coli Proteins, cytotoxic necrotizing factor 1, Retinal, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Rac1 protein, chemistry, biology.protein, medicine.symptom, Ophthalmic Solutions, business, ophthalmic solution, spontaneously hypertensive rats, Muller glia, 030217 neurology & neurosurgery, Retinopathy
وصف الملف: ELETTRONICO
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12
المؤلفون: Qiao-bing, Huang, Min, Dong, Shuang-ming, Song
المصدر: Chinese Journal of Traumatology
مصطلحات موضوعية: Capillary Permeability, vascular, Receptors, Fluid Therapy, Humans, cyclic AMP, Endothelium, Mediator complex, human, Burns, RAC1 protein, Article, Permeability
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13
المؤلفون: Halil Ibrahim Canter, Simone Laupheimer, Bayram Yuksel, Mireia Perez Camps, Ibrahim Vargel, Lorenzo D. Botto, Sevket Ruacan, Nicola Longo, Elif Uz, Mahmut Şamil Sağıroğlu, Ahmad Alzahrani, Bruno Reversade, Omer F. Gerdan, Tokiharu Takahashi, Eeswari Paramalingam, Jingwei Rachel Xiong, Kemal Kosemehmetoglu, Arda Cetinkaya, Zeliha Gormez, Ekim Z. Taskiran, Nurten A. Akarsu
المساهمون: Tıbbi Genetik, Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Moleküler Biyoloji ve Genetik Bölümü., Uz, Elif, Acibadem University Dspace, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction & Development (AR&D), Center for Reproductive Medicine
المصدر: Arda Cetinkaya, Jingwei Rachel Xiong, İbrahim Vargel, Kemal Kösemehmetoğlu, Halil İbrahim Canter, Ömer Faruk Gerdan, Nicola Longo, Ahmad Alzahrani, Mireia Perez Camps, Ekim Zihni Taşkıran, Simone Laupheimer, Lorenzo D Botto, Eeswari Paramalingam, Zeliha Gormez, Elif Uz, Bayram Yuksel, Şevket Ruacan, Mahmut Şamil Sağıroğlu,, Takahashi, T, Bruno Reversade & Nurten Ayse Akarsu 2016, ' Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 Signaling ', American Journal of Human Genetics, vol. 99, no. 2, pp. 299-317 . https://doi.org/10.1016/j.ajhg.2016.06.008
American journal of human genetics, 99(2), 299-317. Cell Pressمصطلحات موضوعية: Male, Pathology, Vascular smooth muscle, Tooth extraction, DOCK1 protein, human, Signal transduction, Gene, Craniofacial region, Intracranial hypertension, Gene inactivation, Skull malformation, Facial bone, 0302 clinical medicine, Genetics(clinical), Gingiva bleeding, Species difference, Phylogeny, Genetics & Heredity, Adaptor proteins, signal transducing, Cell migration, Cell motion, Anatomy, Rac1 protein, 030220 oncology & carcinogenesis, Hemorrhagic shock, Deficiency, Mechanism, Human, medicine.medical_specialty, Vascular malformations, Clinical article, Bone malformation, Spinal cord compression, Article, 03 medical and health sciences, Signal transducing adaptor protein, Complex, Alkaline phosphatase, Skin biopsy, Genetics, Humans, Animal model, Animal experiment, Alleles, Actin, Autosomal recessive disorder, Zebra fish, Animal, Magnetic resonance angiography, medicine.disease, Cytoskeletal proteins, ELMO2 gene, 030104 developmental biology, Jaw, Mutation, Loss of function mutation, Lesions, Protein expression, Angiogenesis, Familial disease, Artificial embolization, 0301 basic medicine, Physiology, Brain hernia, Caldesmon, Growth, Bone deformation, Face asymmetry, Intravascular hemolysis, Animal tissue, Homozygosity, Desmin, Brain ventricle peritoneum shunt, Primary Intraosseous Vascular Malformation, Skull, Parietal Bone, Bone and bones, Exophthalmos, Integrin-linked kinase, Sequencing data, Zebrafish, Genetics (clinical), Priority journal, Allele, Vascular malformation, Homozygote, Lactate dehydrogenase, ELMO2 protein, human, Rac GTP-Binding Proteins, Lymphatic system, Phenotype, Intramembranous ossification, Fibroblast, Female, Rac GTP-binding proteins, North American, Adult, Evolution, molecular, Umbilical hernia, Myosin, Biology, RAC1 protein, human, Saudi, Cell movement, Rac protein, Sclerotherapy, medicine, Cell-migration, Animals, Human tissue, Bone, Species specificity, Tooth disease, Paraplegia, Bone biopsy, Rac1 GTP-binding protein, Vertebrate, Vascularization, Smooth muscle actin, biology.organism_classification, Nonhuman, Metabolism, Congenital blood vessel malformation, Turk (people), Molecular evolution, Controlled study, Cytoskeleton protein
وصف الملف: text/plain; application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document
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14
المؤلفون: Camie Schmitt, Stefan P Berger, Martin Hrabě de Angelis, Julia Calzada-Wack, Thomas Klopstock, Sabine M. Hölter, Oliver von Bohlen und Halbach, Jerzy Adamski, Sergej Kutscherjawy, Volker Endris, Thomas Wieland, Frauke Neff, Karola Wittig, Miriam Schneider, Kai Schönig, Wolfgang Wurst, Jutta Panke, Gudrun A. Rappold, Lillian Garrett, Irene Esposito, Uwe Leimer, Dusan Bartsch, Robert Waltereit, Claire Bacon, Lore Becker, Valerie Gailus-Durner, Helmut Fuchs, Cornelia Prehn
المصدر: The FASEB journal 26(11), 4418-4428 (2012). doi:10.1096/fj.11-202317
مصطلحات موضوعية: Male, rac1 GTP-Binding Protein, genetics [Neuropeptides], Dendritic spine, metabolism [Neuropeptides], RAC1, Biology, mortality [Hydrocephalus], genetics [rac GTP-Binding Proteins], Biochemistry, Srgap3 protein, mouse, White matter, Mice, Rac1 protein, mouse, Neurodevelopmental disorder, pathology [Brain], genetics [Hydrocephalus], ddc:570, Genetics, medicine, Animals, genetics [Schizophrenia], metabolism [rac GTP-Binding Proteins], Social Behavior, Molecular Biology, pathology [Hydrocephalus], Mice, Knockout, Behavior, Animal, cytology [Brain], GTPase-Activating Proteins, Neuropeptides, Brain, medicine.disease, metabolism [GTPase-Activating Proteins], Phenotype, rac GTP-Binding Proteins, medicine.anatomical_structure, metabolism [Brain], Schizophrenia, Knockout mouse, Synaptic plasticity, genetics [GTPase-Activating Proteins], metabolism [Schizophrenia], Female, Neuroscience, Hydrocephalus, Biotechnology
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15Academic Journal
المؤلفون: Choi, Kyuha, Reinhard, Carsten, Serra, Heïdi, Ziolkowski, Piotr A., Underwood, Charles J., Zhao, Xiaohui, Hardcastle, Thomas J., Yelina, Nataliya E., Griffin, Catherine, Jackson, Matthew, Mézard, Christine, McVean, Gil, Copenhaver, Gregory P., Henderson, Ian R.
المصدر: PLoS Genetics, 12(7)
مصطلحات موضوعية: Arabidopsis, Arabidopsis Proteins, Plant Diseases, Heterozygote, Recombination, Genetic, Disease Resistance, Multigene Family, Crosses, Nucleic Acid Hybridization, Genes, Plant, Meiosis, Linkage Disequilibrium, Pollen, Alleles, Genetic Variation, RAC1 protein
Relation: https://doi.org/10.17615/6r18-vv55; https://cdr.lib.unc.edu/downloads/3b591f44g?file=thumbnail; https://cdr.lib.unc.edu/downloads/3b591f44g
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16
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17Academic Journal
المؤلفون: Kang, J, Fei Chong, S.J, Qi Ooi, V.Z, Vali, S, Kumar, A, Kapoor, S, Abbasi, T, Hirpara, J.L, Loh, T, Goh, B.C, Pervaiz, S
المساهمون: PHYSIOLOGY, CANCER SCIENCE INSTITUTE OF SINGAPORE, OTOLARYNGOLOGY, PHARMACOLOGY
المصدر: Unpaywall 20200831
مصطلحات موضوعية: complementary DNA, protein bcl 2, Rac1 protein, reduced nicotinamide adenine dinucleotide phosphate oxidase, small interfering RNA, STAT3 protein, superoxide, venetoclax, human, Article, B cell lymphoma, cancer cell, cancer tissue, cell fractionation, cell survival, centrifugation, computer simulation, controlled study, disease severity, electroporation, follicular lymphoma, genetic transfection, HeLa cell line, Hodgkin disease, human cell, human tissue, large cell lymphoma, mitochondrion, molecular interaction, mutant
Relation: Kang, J, Fei Chong, S.J, Qi Ooi, V.Z, Vali, S, Kumar, A, Kapoor, S, Abbasi, T, Hirpara, J.L, Loh, T, Goh, B.C, Pervaiz, S (2015). Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide. Oncotarget 6 (33) : 34191-34205. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.5763; https://scholarbank.nus.edu.sg/handle/10635/175525
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18Academic Journal
المؤلفون: Shao, X, Kawauchi, K, Shivashankar, G.V, Bershadsky, A.D
المساهمون: BIOLOGICAL SCIENCES, MECHANOBIOLOGY INSTITUTE
المصدر: Unpaywall 20200831
مصطلحات موضوعية: 4 amino 6 [2 [[4 (diethylamino) 1 methylbutyl]amino] 6 methyl 4 pyrimidinyl] 2 methylquinoline, calcimycin, calcium ion, diaphanous related formin 1, diaphanous related formin 3, F actin, guanosine triphosphatase, inverted formin 2, karyopherin beta, lamin b1, methenamine, Nup153 protein, protein, Rac1 protein, unclassified drug, actin polymerization, amino terminal sequence, Article, bioaccumulation, cell function, cell nucleus membrane, cellular distribution, controlled study, cytoplasm, female, gene silencing, human, human cell, immunoprecipitation, nuclear localization signal
Relation: Shao, X, Kawauchi, K, Shivashankar, G.V, Bershadsky, A.D (2015). Novel localization of formin mDia2: importin ?-mediated delivery to and retention at the cytoplasmic side of the nuclear envelope. Biology Open 4 (11) : 1569-1575. ScholarBank@NUS Repository. https://doi.org/10.1242/bio.013649; https://scholarbank.nus.edu.sg/handle/10635/176005
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19Academic Journal
المؤلفون: Hobbs, G. Aaron, Mitchell, Lauren E., Arrington, Megan E., Gunawardena, Harsha P., DeCristo, Molly J., Loeser, Richard F., Chen, Xian, Cox, Adrienne D., Campbell, Sharon L.
المصدر: Free Radical Biology and Medicine, 79
مصطلحات موضوعية: Rac1 GTPases, Free radicals, Humans, HEK293 Cells, RAC1 protein, human, Glutathiolation, Cysteine oxidation, Sulfhydryl Compounds, Reactive nitrogen species, Reactive oxygen species, Protein Stability, Cartilage, Articular, rac1 GTP-Binding Protein, Hydrogen-Ion Concentration, Oxidation-Reduction, Protein Conformation, Amino Acid Sequence, Glutathione, Molecular Sequence Data, Cells, Cultured
Relation: https://doi.org/10.17615/7e6j-fq55; https://cdr.lib.unc.edu/downloads/2r36v515p?file=thumbnail; https://cdr.lib.unc.edu/downloads/2r36v515p
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20
مصطلحات موضوعية: Pancreatic Neoplasms, Carcinoma, Pancreatic Ductal, Environmental Medicine, Extracellular Matrix, Matrix Metalloproteinases, Neoplasm Invasiveness, Neoplastic Stem Cells, NF-kappa B, RAC1 protein, human, Reactive Oxygen Species, Urokinase-Type Plasminogen Activator, Tumor Microenvironment, Humans, Intercellular Signaling Peptides and Proteins, Adenocarcinoma, Models, Biological, Signal Transduction