المؤلفون: Ruth R. Magaye, Feby Savira, Xin Xiong, Kevin Huynh, Peter J. Meikle, Christopher Reid, Bernard L. Flynn, David Kaye, Danny Liew, Bing H. Wang

المصدر: International Journal of Cardiology: Heart & Vasculature, Vol 35, Iss , Pp 100837- (2021)

مصطلحات موضوعية: Cardiac fibroblasts, Collagen synthesis, Dihydrosphingosine, Sphingolipid, TGFβ, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352906721001251; https://doaj.org/toc/2352-9067

URL الوصول: https://doaj.org/article/c45cfbceff2b4806a0ec381c0bc07df0

المؤلفون: R Magaye, Feby Savira, X Xiong, D Donner, H Kiriazis, A Brown, L Huang, N Mellet, K Huynh, P Meikle, C Reid, B Flynn, D Kaye, D Liew, B Wang

مصطلحات موضوعية: Biomedical and clinical sciences, Cardiovascular medicine and haematology, Health sciences, Health services and systems, Public health, Uncategorised value

Relation: http://hdl.handle.net/10779/DRO/DU:26377747.v1

الاتاحة: http://hdl.handle.net/10779/DRO/DU:26377747.v1
https://figshare.com/articles/journal_contribution/Des-1_Inhibition_Attenuated_Cardiac_Remodelling_in_a_Mouse_Model_of_Ischaemia_Reperfusion/26377747

المؤلفون: Feby Savira, AR Kompa, DJ Kelly, R Magaye, X Xiong, L Huang, D Liew, C Reid, D Kaye, CV Scullino, SM Pitson, BL Flynn, BH Wang

مصطلحات موضوعية: Pharmacology and pharmaceutical sciences not elsewhere classified, Science & Technology, Life Sciences & Biomedicine, Pharmacology & Pharmacy, Dihydroceramide desaturase 1, Endothelium, Vasorelaxation, Wound healing, Indoxyl sulfate, TO-MESENCHYMAL TRANSITION, UREMIC TOXIN, CARDIORENAL SYNDROME, CERAMIDE, PROLIFERATION, DYSFUNCTION, MIGRATION, CELLS, ACCUMULATION, SURVIVAL, 3214 Pharmacology and pharmaceutical sciences

Relation: http://hdl.handle.net/10536/DRO/DU:30159100; https://figshare.com/articles/journal_contribution/The_effect_of_dihydroceramide_desaturase_1_inhibition_on_endothelial_impairment_induced_by_indoxyl_sulfate/20634273

الاتاحة: http://hdl.handle.net/10536/DRO/DU:30159100
https://figshare.com/articles/journal_contribution/The_effect_of_dihydroceramide_desaturase_1_inhibition_on_endothelial_impairment_induced_by_indoxyl_sulfate/20634273

المؤلفون: Feby Savira, R Magaye, CV Scullino, BL Flynn, SM Pitson, D Anderson, DJ Creek, Y Hua, X Xiong, L Huang, D Liew, C Reid, D Kaye, AR Kompa, BH Wang

مصطلحات موضوعية: Pharmacology and pharmaceutical sciences not elsewhere classified, Environmental management not elsewhere classified, Science & Technology, Life Sciences & Biomedicine, Toxicology, Uremic toxins, Dihydroceramide desaturase 1, Desl inhibitor, Sphingolipids, NF-KAPPA-B, INDOXYL SULFATE, OXIDATIVE STRESS, NATRIURETIC PEPTIDES, CARDIORENAL SYNDROME, CARDIAC FIBROSIS, HYPERTROPHY, CERAMIDE, INDUCTION, ACCUMULATION, 3214 Pharmacology and pharmaceutical sciences

Relation: http://hdl.handle.net/10536/DRO/DU:30159102; https://figshare.com/articles/journal_contribution/Sphingolipid_imbalance_and_inflammatory_effects_induced_by_uremic_toxins_in_heart_and_kidney_cells_are_reversed_by_dihydroceramide_desaturase_1_inhibition/20634264

الاتاحة: http://hdl.handle.net/10536/DRO/DU:30159102
https://figshare.com/articles/journal_contribution/Sphingolipid_imbalance_and_inflammatory_effects_induced_by_uremic_toxins_in_heart_and_kidney_cells_are_reversed_by_dihydroceramide_desaturase_1_inhibition/20634264

المؤلفون: Feby Savira, AR Kompa, R Magaye, X Xiong, L Huang, BM Jucker, RN Willette, DJ Kelly, BH Wang

مصطلحات موضوعية: Biochemistry and cell biology not elsewhere classified, Pharmacology and pharmaceutical sciences not elsewhere classified, Science & Technology, Life Sciences & Biomedicine, Medicine, Research & Experimental, Pharmacology & Pharmacy, Research & Experimental Medicine, Apoptosis signal-regulating kinase 1, Endothelium, Vasorelaxation Wound healing, Indoxyl sulfate, 3101 Biochemistry and cell biology

Relation: http://hdl.handle.net/10536/DRO/DU:30159105

الاتاحة: http://hdl.handle.net/10536/DRO/DU:30159105
https://figshare.com/articles/journal_contribution/Apoptosis_signal-regulating_kinase_1_inhibition_reverses_deleterious_indoxyl_sulfate-mediated_endothelial_effects/20634249

المؤلفون: Bernard L. Flynn, Ruth R Magaye, Xin Xiong, Peter J Meikle, Danny Liew, Feby Savira, Kevin Huynh, David M. Kaye, Bing Hui Wang, Christopher M. Reid

المصدر: International Journal of Cardiology. Heart & Vasculature
International Journal of Cardiology: Heart & Vasculature, Vol 35, Iss, Pp 100837-(2021)

مصطلحات موضوعية: RPS6, ribosomal protein S6, S1PR1, sphingosine -1-phosphate receptor 1, MMP2, matrix metalloproteinase 2, Sphingolipid, MA3PK, mitogen activated protein kinase kinase kinase, chemistry.chemical_compound, S1P, sphingosine-1 Phosphate, Sph, sphingosine, TIMP1, tissue inhibitor of metalloproteinase 1, TGFβ, transforming growth factor β, Medicine, S1PR1, Cardiac fibroblasts, biology, Dihydrosphingosine, Cell biology, S1PRs, sphingosine 1 phosphate receptor 1-5, Collagen synthesis, Sphingosine kinase 1, Coll1a1, collagen 1a1, mTOR, mammalian target for rapamycin, d7dhSph, deuterated dihydrosphingosine, lipids (amino acids, peptides, and proteins), MAPK, mitogren activated protein kinase, Cardiology and Cardiovascular Medicine, Ceramide, Cer, ceramide, SK1, sphingosine kinase 1, TAK1, transforming growth factor β activating kinase 1, CTGF, connective tissue growth factor, TGFβ, TGF beta signaling pathway, Diseases of the circulatory (Cardiovascular) system, Cer1P, ceramide 1 phosphate, Sphingosine-1-phosphate, NCF, neonatal cardiac fibroblasts, ComputingMethodologies_COMPUTERGRAPHICS, Original Paper, dhCer, dihydroceramide, Sphingosine, business.industry, dhS1P, dihydrosphingosine 1 phosphate, Degs1, dihydroceramide desaturase 1 gene, chemistry, RC666-701, ECM, extracellular matrix inhibitor of nuclear kappa B (NFKβ) kinase alpha and beta (IKKα/β), Akt, protein kinase B, biology.protein, MI, myocardial infarct, business, Des-1, dihydroceramide desaturase 1 enzyme, Transforming growth factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7107d8c58bf953de354bb354b3a6ef20
https://pubmed.ncbi.nlm.nih.gov/34277924

المؤلفون: Dovile Anderson, David M. Kaye, Bernard L. Flynn, Danny Liew, Bing Hui Wang, Carmen V. Scullino, Ruth R Magaye, Darren J. Creek, Christopher M. Reid, Yue Hua, Andrew R Kompa, Li Huang, Xin Xiong, Stuart M. Pitson, Feby Savira

المساهمون: Savira, Feby, Magaye, Ruth, Scullino, Carmen V, Flynn, Bernard L, Pitson, Stuart M, Anderson, Dovile, Creek, Darren J, Hua, Yue, Xiong, Xin, Huang, Li, Liew, Danny, Reid, Christopher, Kaye, David, Kompa, Andrew R, Wang, Bing Hui

مصطلحات موضوعية: Ceramide, Cardiac fibrosis, uremic toxins, Pharmacology, Toxicology, medicine.disease_cause, Rats, Sprague-Dawley, chemistry.chemical_compound, des1 inhibitor, medicine, Animals, Humans, dihydroceramide desaturase 1, Enzyme Inhibitors, Renal Insufficiency, Chronic, Toxins, Biological, Uremia, Kidney, Sphingolipids, sphingolipids, Chemistry, General Medicine, Dihydroceramide desaturase, medicine.disease, Sphingolipid, Rats, medicine.anatomical_structure, Cardiovascular Diseases, Models, Animal, Oxidoreductases, Oxidative stress, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2841aa34de246c4a3de7fdcc183096f
https://hdl.handle.net/11541.2/148203

المؤلفون: Li Huang, David M. Kaye, Bing Hui Wang, Feby Savira, Christopher M. Reid, Bernard L. Flynn, Danny Liew, Ruth R Magaye, Xin Xiong, Yue Hua

المصدر: The international journal of biochemistrycell biology. 134

مصطلحات موضوعية: 0301 basic medicine, Cardiac fibrosis, Cardiomegaly, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Sphingosine, Transforming Growth Factor beta, medicine, Animals, Myocytes, Cardiac, Protein kinase B, PI3K/AKT/mTOR pathway, Cells, Cultured, Phosphoinositide-3 Kinase Inhibitors, biology, Kinase, TOR Serine-Threonine Kinases, Cell Biology, Transforming growth factor beta, Fibroblasts, medicine.disease, Fibrosis, Cell biology, Rats, 030104 developmental biology, chemistry, Sphingosine kinase 1, Animals, Newborn, 030220 oncology & carcinogenesis, biology.protein, Collagen, Signal transduction, Phosphatidylinositol 3-Kinase, Proto-Oncogene Proteins c-akt, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b0140b78ba8fa319bd38bdf5e2b093
https://pubmed.ncbi.nlm.nih.gov/33609744

المؤلفون: Feby Savira, R Magaye, D Liew, C Reid, DJ Kelly, AR Kompa, SJ Sangaralingham, JC Burnett, D Kaye, BH Wang

مصطلحات موضوعية: Pharmacology and pharmaceutical sciences not elsewhere classified, BOUND UREMIC TOXINS, CARDIOVASCULAR-DISEASE, CLINICAL-IMPLICATIONS, GLOMERULAR-FILTRATION-RATE, INDOXYL SULFATE, Life Sciences & Biomedicine, LOW-PROTEIN DIET, NEPRILYSIN INHIBITION, Pharmacology & Pharmacy, RENAL REPLACEMENT THERAPY, Science & Technology, SYNDROME PATHOPHYSIOLOGY, VENTRICULAR ASSIST DEVICES, 3201 Cardiovascular medicine and haematology

Relation: http://hdl.handle.net/10536/DRO/DU:30159109

الاتاحة: http://hdl.handle.net/10536/DRO/DU:30159109
https://figshare.com/articles/journal_contribution/Cardiorenal_syndrome_Multi-organ_dysfunction_involving_the_heart_kidney_and_vasculature/20634237

المؤلفون: Feby Savira, R Magaye, Y Hua, D Liew, D Kaye, T Marwick, BH Wang

مصطلحات موضوعية: Pharmacology and pharmaceutical sciences not elsewhere classified, Environmental management not elsewhere classified, Cardiorenal syndrome, CHRONIC KIDNEY-DISEASE, INDOXYL SULFATE, INDUCED CELLULAR SENESCENCE, Intracellular signaling pathway, Life Sciences & Biomedicine, NF-KAPPA-B, ORGANIC ANION TRANSPORTERS, OSTEOBLAST-SPECIFIC PROTEINS, OXIDATIVE STRESS, P-CRESYL SULFATE, Pharmacological targets, Protein-bound uremic toxin, REGULATING KINASE 1, Science & Technology, Toxicology, VEIN ENDOTHELIAL-CELLS, 3214 Pharmacology and pharmaceutical sciences, 3208 Medical physiology

Relation: http://hdl.handle.net/10536/DRO/DU:30159114

الاتاحة: http://hdl.handle.net/10536/DRO/DU:30159114
https://figshare.com/articles/journal_contribution/Molecular_mechanisms_of_protein-bound_uremic_toxin-mediated_cardiac_renal_and_vascular_effects_underpinning_intracellular_targets_for_cardiorenal_syndrome_therapy/20634222

المؤلفون: Peter J. Meikle, Christopher A. Reid, R. Magaye, Kevin Huynh, Li Huang, Helen Kiriazis, N. Mellet, Bernard L. Flynn, Feby Savira, Danny Liew, X. Xiong, David M. Kaye, Bing Hui Wang, D. Donner, A. Brown

المصدر: Heart, Lung and Circulation. 30:S119

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, Internal medicine, Ischaemia reperfusion, Cardiology, Medicine, Cardiology and Cardiovascular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9358cb3a600246a5efaa8e2af104d506
https://doi.org/10.1016/j.hlc.2021.06.061

المؤلفون: Ruth R Magaye, Yue Hua, Bernard L. Flynn, Danny Liew, David M. Kaye, Xin Xiong, Bing Hui Wang, Christopher M. Reid, Feby Savira, Li Huang

المصدر: Cellular Signalling. 72:109629

مصطلحات موضوعية: 0301 basic medicine, Time Factors, Cardiac fibrosis, Smad2 Protein, Thiophenes, Models, Biological, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Sphingosine, Transforming Growth Factor beta, Fibrosis, medicine, Extracellular, Animals, Myocytes, Cardiac, RNA, Messenger, STAT1, Phosphorylation, STAT3, Janus Kinases, Oxadiazoles, Tissue Inhibitor of Metalloproteinase-1, biology, Chemistry, Myocardium, JAK-STAT signaling pathway, Cell Differentiation, Hypertrophy, Cell Biology, Fibroblasts, medicine.disease, Cell biology, Phosphotransferases (Alcohol Group Acceptor), STAT Transcription Factors, 030104 developmental biology, Animals, Newborn, Gene Expression Regulation, 030220 oncology & carcinogenesis, biology.protein, Matrix Metalloproteinase 2, Collagen, Lysophospholipids, Janus kinase, Biomarkers, Signal Transduction, Transforming growth factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090b177687ccde3ffdae33b612da94b0
https://doi.org/10.1016/j.cellsig.2020.109629

المؤلفون: Y Hua, R Magaye, Feby Savira, L Huang, B Flynn, B Wang

مصطلحات موضوعية: Biomedical and clinical sciences, Cardiovascular medicine and haematology, Health sciences, Health services and systems, Public health, Uncategorised value

Relation: http://hdl.handle.net/10779/DRO/DU:26377450.v1

الاتاحة: http://hdl.handle.net/10779/DRO/DU:26377450.v1
https://figshare.com/articles/journal_contribution/Dihydroceramide_Desaturase-1_Inhibitor_MIPS247_Ameliorates_Cardiac_Cellular_Remodelling/26377450

المؤلفون: R Magaye, Feby Savira, Y Hua, L Huang, B Flynn, B Wang

مصطلحات موضوعية: Biomedical and clinical sciences, Cardiovascular medicine and haematology, Health sciences, Health services and systems, Public health, Uncategorised value

Relation: http://hdl.handle.net/10779/DRO/DU:26377456.v1; https://figshare.com/articles/journal_contribution/Sphingosine_1_Phosphate_Mediates_Cardiac_Fibrosis_Through_JAK_STAT_Signalling_Pathways/26377456

الاتاحة: http://hdl.handle.net/10779/DRO/DU:26377456.v1
https://figshare.com/articles/journal_contribution/Sphingosine_1_Phosphate_Mediates_Cardiac_Fibrosis_Through_JAK_STAT_Signalling_Pathways/26377456

المؤلفون: Bernard L. Flynn, X. Xiong, F. Sevira, R. Magaye, Bing Hui Wang

المصدر: Heart, Lung and Circulation. 29:S86

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Signalling, business.industry, Dihydrosphingosine-1-phosphate, Medicine, Cardiology and Cardiovascular Medicine, business, Protein kinase B, PI3K/AKT/mTOR pathway, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c6e5afcbb42ec94530d28342494dd863
https://doi.org/10.1016/j.hlc.2020.09.119

المؤلفون: Bernard L. Flynn, Li Huang, R. Magaye, Yue Hua, Bing Hui Wang, Feby Savira

المصدر: Heart, Lung and Circulation. 27:S132

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, chemistry.chemical_compound, chemistry, business.industry, Cardiac fibrosis, Cancer research, Medicine, JAK-STAT signaling pathway, Sphingosine-1-phosphate, Cardiology and Cardiovascular Medicine, business, medicine.disease, Signalling pathways

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cd20455b646cda0fa2cec8324cc37663
https://doi.org/10.1016/j.hlc.2018.06.198

المؤلفون: R. Magaye, Bernard L. Flynn, Bing Hui Wang, Yue Hua, Li Huang, Feby Savira

المصدر: Heart, Lung and Circulation. 27:S93

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, business.industry, Medicine, Dihydroceramide desaturase, Cardiology and Cardiovascular Medicine, business, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6c7f230541b5d4ebd7492bddc68dfd1f
https://doi.org/10.1016/j.hlc.2018.06.113