المؤلفون: Li, Ling, Feng, Lijian, Shi, Minlong, Zeng, Jue, Chen, Jason, Zhong, Li, Huang, Li, Guo, Weihui, Huang, Ying, Qi, Vicky, Lu, Chris, Li, En, Zhao, Kehao, Gu, Justin

Relation: Li, Ling, Feng, Lijian, Shi, Minlong, Zeng, Jue, Chen, Jason, Zhong, Li, Huang, Li, Guo, Weihui, Huang, Ying, Qi, Vicky, Lu, Chris, Li, En, Zhao, Kehao and Gu, Justin (2017) Split luciferase-based biosensors for characterizing EED binders. Analytical Biochemistry, 522. pp. 37-45. ISSN 10960309

الاتاحة: https://oak.novartis.com/30384/
https://doi.org/10.1016/j.ab.2017.01.014

المؤلفون: Lingel, Andreas, Bussiere, Dirksen, Cantwell, John, Dillon, Michael, Fu, Xingnian, Fuller, John, Gu, Justin, Huang, Ying, Jiang, Xiangqing, Li, Ling, Liang, Fang, Lindvall, Mika, Mckenna, Maureen, Qi, Vicky, Rao, Weijun, Sendzik, Martin, Sheng, Xijun, Shu, Wei, Shultz, Michael, Taft, Benjamin, Wang, Long, Zeng, Jue, Zhang, Maya, Zhang, Hailong, Zhao, Kehao, Gabriel, Tobias

Relation: Lingel, Andreas, Bussiere, Dirksen, Cantwell, John, Dillon, Michael, Fu, Xingnian, Fuller, John, Gu, Justin, Huang, Ying, Jiang, Xiangqing, Li, Ling, Liang, Fang, Lindvall, Mika, Mckenna, Maureen, Qi, Vicky, Rao, Weijun, Sendzik, Martin, Sheng, Xijun, Shu, Wei, Shultz, Michael, Taft, Benjamin, Wang, Long, Zeng, Jue, Zhang, Maya, Zhang, Hailong, Zhao, Kehao and Gabriel, Tobias (2017) Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Methyltransferase PRC2. Jounal of Medicinal Chemistry.

الاتاحة: https://oak.novartis.com/30383/

المؤلفون: Huang, Ying, Zhang, Jeff, Yu, Zhengtian, Wang, Youzhen, Lingel, Andreas, Qi, Vicky, Gu, Justin, Zhao, Kehao, Wang, Long, Fu, Xingnian, Sun, Yongfeng, Jiang, Xiangqing, Zhang, Jiangwei, Zhang, Chunye, Li, Ling, Liu, Yueqin, Zhang, Maya, Zhang, Lijun, Zhao, Mengxi, Fang, Douglas, Shultz, Michael, Mi, Yuan, Gao, Zhenting, Oyang, Counde, Zhang , Hailong, Liu , Xianghui, Zhang, Qiong, Zhang, Chao, Gou, Haibing, Dillon, Michael, Atadja, Peter, Zeng, Jue

Relation: Huang, Ying, Zhang, Jeff, Yu, Zhengtian, Wang, Youzhen, Lingel, Andreas, Qi, Vicky, Gu, Justin, Zhao, Kehao, Wang, Long, Fu, Xingnian, Sun, Yongfeng, Jiang, Xiangqing, Zhang, Jiangwei, Zhang, Chunye, Li, Ling, Liu, Yueqin, Zhang, Maya, Zhang, Lijun, Zhao, Mengxi, Fang, Douglas, Shultz, Michael, Mi, Yuan, Gao, Zhenting, Oyang, Counde, Zhang , Hailong, Liu , Xianghui, Zhang, Qiong, Zhang, Chao, Gou, Haibing, Dillon, Michael, Atadja, Peter and Zeng, Jue (2017) Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy. Journal of Medicinal Chemistry, 60 (6). pp. 2215-2226. ISSN 1520-4804

الاتاحة: https://oak.novartis.com/30365/
https://doi.org/10.1021/acs.jmedchem.6b01576

المؤلفون: Qi, Vicky, Zhao, Kehao, Gu, Justin, Huang, Ying, Wang, Youzhen, Zhang, Hailong, Zhang, Maya, Zhang, Jeff, Yu, Zhengtian, Li, Ling, Teng, Lin, Chuai, Shannon, Zhang, Chao, Zhao, Mengxi, Chen, Zijun, Fang, Douglas, Fei, Qi, Feng, Leying, Feng, Lijian, Gao, Yuan, Ge, Hui, Ge, Xinjian, Li, Guobin, Lingel, Andreas, Lin, Ying, Liu, Yueqin, Luo, Fangjun, Shi, Minlong, Wang, Long, Wang, Zhaofu, Yu, Yanyan, Zeng, Jue, Zeng, Chenhui, Chen, Ho Man, Zhang, Lijun, Zhang, Qiong, Zhou, Shaolian, Oyang, Counde, Atadja, Peter, Li, En

Relation: Qi, Vicky, Zhao, Kehao, Gu, Justin, Huang, Ying, Wang, Youzhen, Zhang, Hailong, Zhang, Maya, Zhang, Jeff, Yu, Zhengtian, Li, Ling, Teng, Lin, Chuai, Shannon, Zhang, Chao, Zhao, Mengxi, Chen, Zijun, Fang, Douglas, Fei, Qi, Feng, Leying, Feng, Lijian, Gao, Yuan, Ge, Hui, Ge, Xinjian, Li, Guobin, Lingel, Andreas, Lin, Ying, Liu, Yueqin, Luo, Fangjun, Shi, Minlong, Wang, Long, Wang, Zhaofu, Yu, Yanyan, Zeng, Jue, Zeng, Chenhui, Chen, Ho Man, Zhang, Lijun, Zhang, Qiong, Zhou, Shaolian, Oyang, Counde, Atadja, Peter and Li, En (2017) An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED. Nature Chemical Biology.

الاتاحة: https://oak.novartis.com/29971/

المؤلفون: Qi, Vicky, Chan, Ho Man, Atadja, Peter, Li, Ling, Chuai, Shannon, Lin, Ying, Gu, Justin, Zhang, Ji, Mi, Yuan, Zhang, Maya, Zhao, Kehao, Li, En, Teng, Lin, Zeng, Jue, Li, Min, Fan, Hong, Yan, Xiaoxia, Fang, Jialuo, Zhou, Tao, Feng, Grace, Yang, Teddy, Liu, Xianghui, Zhang, Regene, Li, Coben, Chen, Jason

Relation: Qi, Vicky, Chan, Ho Man, Atadja, Peter, Li, Ling, Chuai, Shannon, Lin, Ying, Gu, Justin, Zhang, Ji, Mi, Yuan, Zhang, Maya, Zhao, Kehao, Li, En, Teng, Lin, Zeng, Jue, Li, Min, Fan, Hong, Lin, Ying, Yan, Xiaoxia, Fang, Jialuo, Zhou, Tao, Feng, Grace, Yang, Teddy, Liu, Xianghui, Zhang, Regene, Li, Coben and Chen, Jason (2012) Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation. Proceedings of National Academy of Sciences of the United States of America, 109 (52). pp. 21360-21365. ISSN 1091-6490; PMID: 23236167; doi:10.1073/pnas.1210371110

الاتاحة: https://oak.novartis.com/7940/
http://www.pnas.org/content/109/52/21360.abstract?sid=783db3ec-d262-4d0c-ba3b-443978603de4