المؤلفون: Ali, Ali Mohamed, Solans, Belén P, Hesseling, Anneke C, Winckler, Jana, Schaaf, H Simon, Draper, Heather R, van der Laan, Louvina, Hughes, Jennifer, Fourie, Barend, Nielsen, James, Wiesner, Lubbe, Garcia-Prats, Anthony J, Savic, Radojka M

المصدر: Antimicrobial Agents and Chemotherapy. 68(1)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Emerging Infectious Diseases, HIV/AIDS, Infectious Diseases, Pediatric AIDS, Pediatric, Rare Diseases, Tuberculosis, Sexually Transmitted Infections, 6.1 Pharmaceuticals, Infection, Good Health and Well Being, Adolescent, Child, Child, Preschool, Humans, Clofazimine, HIV Infections, Rifampin, Tuberculosis, Multidrug-Resistant, pharmacokinetics, tuberculosis, clofazimine, pediatrics, QT prolongation, Microbiology, Medical Microbiology, Medical microbiology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/74c1g5jw
https://escholarship.org/content/qt74c1g5jw/qt74c1g5jw.pdf

المؤلفون: Milena Kovačević, Milica Ćulafić, Marija Jovanović, Sandra Vezmar Kovačević, Katarina Vučićević, Branislava Miljković, Predrag Stevanović, Slavica Radovanović

المصدر: Brazilian Journal of Pharmaceutical Sciences, Vol 61 (2025)

مصطلحات موضوعية: QT interval, QT prolongation, Drug-induced, Drug-drug interactions, Cardiac patients, Patient safety, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502025000100313&lng=en&tlng=en; http://www.scielo.br/pdf/bjps/v61/2175-9790-bjps-61-e24026.pdf; https://doaj.org/toc/2175-9790

URL الوصول: https://doaj.org/article/258bf49c9a8d4e3194a210706eb9c1d5

المؤلفون: Hatice Aslan Sirakaya, Kaniye Aydin, Ali Cetinkaya

المصدر: Van Tıp Dergisi, Vol 31, Iss 3, Pp 232-238 (2024)

مصطلحات موضوعية: atrial fibrillation, ecg, qt prolongation, sepsis, Medicine

وصف الملف: electronic resource

Relation: https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vmj&un=VMJ-92486; https://doaj.org/toc/2587-0351

URL الوصول: https://doaj.org/article/dcb4df32b0994874afd9accc56a305a9

المؤلفون: Yuan, Neal, Oesterle, Adam, Botting, Patrick, Chugh, Sumeet, Albert, Christine, Ebinger, Joseph, Ouyang, David

مصطلحات موضوعية: Health Services and Systems, Health Sciences, Heart Disease, Patient Safety, Clinical Trials and Supportive Activities, Cardiovascular, Clinical Research, ECG, EHR, QT prolongation, accessibility, assessment, clinical data, clinical data monitoring, comorbidity interaction, demographic interaction, drug toxicity, electrocardiogram, electronic health records, medication effects, medication monitoring, monitoring, pharmacovigilance, Cardiovascular medicine and haematology, Health services and systems

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6cr1701g

المؤلفون: Mohammad Rezaei Zadeh Rukerd, Fatemeh Rafiei Shahrbabaki, Mitra Movahedi, Amin Honarmand, Pouria Pourzand, Amirhossein Mirafzal

المصدر: International Journal of Emergency Medicine, Vol 17, Iss 1, Pp 1-8 (2024)

مصطلحات موضوعية: Ondansetron, QT prolongation, Prediction, Emergency department, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1865-1380

URL الوصول: https://doaj.org/article/b8b4dd7d50e244a2a40015ef29a60192

المؤلفون: Saki Yokohara, Masayuki Hashiguchi, Tsuyoshi Shiga

المصدر: Journal of Arrhythmia, Vol 39, Iss 6, Pp 928-936 (2023)

مصطلحات موضوعية: Japan, psychotherapeutic drug, QT prolongation, spontaneous reporting system, ventricular arrhythmia, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1880-4276; https://doaj.org/toc/1883-2148

URL الوصول: https://doaj.org/article/6ef3095dd8e746648e1f348d59048d3b

المؤلفون: Yun, Hwi-Yeol, Chang, Vincent, Radtke, Kendra K, Wang, Qianwen, Strydom, Natasha, Chang, Min Jung, Savic, Radojka M

المصدر: Open Forum Infectious Diseases. 9(3)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Tuberculosis, Clinical Research, Emerging Infectious Diseases, Rare Diseases, Infectious Diseases, Antimicrobial Resistance, HIV/AIDS, Sexually Transmitted Infections, Clinical Trials and Supportive Activities, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, Infection, Good Health and Well Being, lung lesion distribution model, moxifloxacin, multidrug resistance tuberculosis, population pharmacokinetics, QT prolongation model, Clinical sciences, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0474p6nf
https://escholarship.org/content/qt0474p6nf/qt0474p6nf.pdf

المؤلفون: Johan Frederik Mebus Meyer Christensen, Jonathan Hugo Jürgens-Lahnstein, Afrim Iljazi, Stig Ejdrup Andersen, Morten Dahl, Gesche Jürgens

المصدر: Pharmaceuticals, Vol 17, Iss 10, p 1373 (2024)

مصطلحات موضوعية: medication review, pharmacotherapy, QT prolongation, adverse-drug reaction, psychotropics, antidepressant agents, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1424-8247/17/10/1373; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/849f0f0d1b1a4faebfd1af0bd0846df8

المؤلفون: Joanna Parkinson, Jesper Sundell, Dinko Rekić, Karin Nelander, Hans Ericsson, Ahmad Ebrahimi, Corina Dota, Mikael Sunnåker

المصدر: Pharmacology Research & Perspectives, Vol 12, Iss 2, Pp n/a-n/a (2024)

مصطلحات موضوعية: biopharmaceutics, drug safety, heart failure, modeling and simulation, QT prolongation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2052-1707

URL الوصول: https://doaj.org/article/dff24b86cd934119a37837e539c8eac6

المؤلفون: Muhammad Umer Riaz Gondal, John Lemoine, Jared Segal, Zainab Kiyani, Muhammad Ibraiz Bilal, Fawwad Ansari, Brian McCauley

المصدر: European Journal of Case Reports in Internal Medicine (2024)

مصطلحات موضوعية: oxaliplatin, capecitabine, qt prolongation, cardiogenic shock, Medicine

وصف الملف: electronic resource

Relation: https://www.ejcrim.com/index.php/EJCRIM/article/view/4417; https://doaj.org/toc/2284-2594

URL الوصول: https://doaj.org/article/4969dbdc802a4f65823ac68584792afc

المؤلفون: Deemah S. Alsuhaibani, Heba H. Edrees, Thamir M Alshammari

المصدر: Saudi Pharmaceutical Journal, Vol 31, Iss 7, Pp 1360-1366 (2023)

مصطلحات موضوعية: COVID-19, Hydroxychloroquine, Remdesivir, QT prolongation, FAERS, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1319016423001494; https://doaj.org/toc/1319-0164

URL الوصول: https://doaj.org/article/de9576e3849d47d289d6e682299596e1

المؤلفون: Kamaldeep Singh, Arpit Jain, Ishita Panchal, Hritik Madan, Anubhav Gupta, Aakanksha Sharma, Surabhi Gupta, Anastas Kostojchin, Anmol Singh, Ishanjit Singh Sandhu, Jayesh Mittal, Loveleen Bhogal, Shiny Teja Kolli, Vishal Reddy Bejugam, Salil Chaturvedi, Akhil Bhalla, Shobhit Piplani

المصدر: The Egyptian Heart Journal, Vol 75, Iss 1, Pp 1-11 (2023)

مصطلحات موضوعية: QT prolongation, Ondansetron, Arrhythmia, Drug safety, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2090-911X

URL الوصول: https://doaj.org/article/1d998aec109548dcb0ffebb1e41e3fc1

المؤلفون: Ana Isabel Pinho, Cátia Oliveira, Luís Daniel Santos, Catarina Marques, André Cabrita, Paula Dias, Gonçalo Pestana, Carla Sousa, Rui André Rodrigues

المصدر: Monaldi Archives for Chest Disease (2024)

مصطلحات موضوعية: Takotsubo syndrome, QT prolongation, QT interval, Medicine

وصف الملف: electronic resource

Relation: https://www.monaldi-archives.org/index.php/macd/article/view/2934; https://doaj.org/toc/1122-0643; https://doaj.org/toc/2532-5264

URL الوصول: https://doaj.org/article/503788163a864ad3a93ceb138a6267db

المؤلفون: Ni Zhang, Lanlan Gan, Guiyuan Xiang, Jing Xu, Tingting Jiang, Yanping Li, Yuanlin Wu, Rui Ni, Yao Liu

المصدر: Frontiers in Pharmacology, Vol 14 (2024)

مصطلحات موضوعية: cholinesterase inhibitors, torsade de pointes/QT prolongation, pharmacovigilance study, drug safety, FAERS, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1343650/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/12f3855670d94599a1c46eccb1d15c80

المؤلفون: Lukito, Antonia Anna, Wirawan, Marco, Yonas, Emir, Pranata, Raymond

المصدر: Bali Medical Journal; Vol. 14 No. 1 (2025): In Press Online : January 2025; 211-213 ; 2302-2914 ; 2089-1180

مصطلحات موضوعية: QT prolongation, jellyfish, sting, envenomation, coagulation

وصف الملف: application/pdf

Relation: https://balimedicaljournal.org/index.php/bmj/article/view/5436/3498; https://balimedicaljournal.org/index.php/bmj/article/view/5436

الاتاحة: https://balimedicaljournal.org/index.php/bmj/article/view/5436
https://doi.org/10.15562/bmj.v14i1.5436

المؤلفون: Camara, Mahamadou D., Zhou, Yitian, Dara, Antoine, Tékété, Mamadou M., de Sousa, Taís Nóbrega, Sissoko, Sékou, Dembélé, Laurent, Ouologuem, Nouhoun, Togo, Amadou Hamidou, Alhousseini, Mohamed L., Fofana, Bakary, Sagara, Issaka, Djimde, Abdoulaye A., Gil, Pedro J., Lauschke, Volker M.

المساهمون: Global Health and Tropical Medicine (GHTM), Instituto de Higiene e Medicina Tropical (IHMT)

مصطلحات موضوعية: cardiotoxicity, hERG, Kv11.1, long QT, malaria, QT prolongation, Pharmacology, Pharmacology (medical), Infectious Diseases, SDG 3 - Good Health and Well-being

Relation: PURE: 100536907; Scopus: 85192114353; WOS: 001193584800001; PubMed: 38546223; PubMedCentral: PMC11064487; http://hdl.handle.net/10362/172875

الاتاحة: http://hdl.handle.net/10362/172875
https://doi.org/10.1128/aac.01390-23

المؤلفون: Rana, Mohamed, Ahmad, Almuhanna, Hawra, Alajwad, Amin, Elshehawey, Abdulmohsen, Almusaad, Muneera, AlTaweel

المصدر: International Journal of Clinical Science and Medical Research, 04(06), 209–218, (2024-06-22)

مصطلحات موضوعية: T-wave alternans, QT prolongation, chronic kidney disease, ventricular arrhythmias, sudden cardiac death, electrolyte imbalance, hemodialysis

Relation: https://doi.org/10.5281/zenodo.12361249; https://doi.org/10.5281/zenodo.12361250; oai:zenodo.org:12361250

الاتاحة: https://doi.org/10.5281/zenodo.12361250

المؤلفون: Garcia Cruz, Jian, Pena, Alberto, Perez Rodriguez, Julio, Othon Martinez, Diana, Kondapavuluru, Roy

المصدر: Research Symposium

مصطلحات موضوعية: Cocaine, QT prolongation, ekg changes, stimulants, Medicine and Health Sciences

وصف الملف: application/pdf

Relation: https://scholarworks.utrgv.edu/somrs/2024/posters/16; https://scholarworks.utrgv.edu/context/somrs/article/1358/viewcontent/Cocaine_Induced_QT_Prolongation.pdf

الاتاحة: https://scholarworks.utrgv.edu/somrs/2024/posters/16
https://scholarworks.utrgv.edu/context/somrs/article/1358/viewcontent/Cocaine_Induced_QT_Prolongation.pdf

المؤلفون: R. F. Nasyrova, A. V. Kidyaeva, M. M. Petrova, N. A. Shnayder, Р. Ф. Насырова, А. В. Кидяева, М. М. Петрова, Н. А. Шнайдер

المساهمون: The study was performed without external funding., Работа выполнена без спонсорской поддержки

المصدر: Safety and Risk of Pharmacotherapy; 2024: Online First ; Безопасность и риск фармакотерапии; 2024: Online First ; 2619-1164 ; 2312-7821 ; undefined

مصطلحات موضوعية: лечение, drug safety, adverse drug reactions, long QT syndrome, antipsychotic-induced QT prolongation, Torsade de Pointes, sudden death syndrome, mental disorder, treatment, безопасность лекарственных средств, нежелательные реакции, синдром удлинения QT, антипсихотик-индуцированное удлинение QT, Тorsade de Рointes, синдром внезапной смерти, психическое расстройство

وصف الملف: application/pdf

Relation: https://www.risksafety.ru/jour/article/view/410/1062; https://www.risksafety.ru/jour/article/view/410/1073; https://www.risksafety.ru/jour/article/view/410/1075; https://www.risksafety.ru/jour/article/view/410/1077; https://www.risksafety.ru/jour/article/view/410/1078; https://www.risksafety.ru/jour/article/view/410/1079; https://www.risksafety.ru/jour/article/view/410/1080; https://www.risksafety.ru/jour/article/view/410/1093; https://www.risksafety.ru/jour/article/view/410/1098; https://www.risksafety.ru/jour/article/view/410/1100; https://www.risksafety.ru/jour/article/view/410/1105; https://www.risksafety.ru/jour/article/view/410/1115; https://www.risksafety.ru/jour/article/downloadSuppFile/410/476; https://www.risksafety.ru/jour/article/downloadSuppFile/410/491; https://www.risksafety.ru/jour/article/downloadSuppFile/410/492; https://www.risksafety.ru/jour/article/downloadSuppFile/410/493; https://www.risksafety.ru/jour/article/downloadSuppFile/410/519; Chohan PS, Mittal R, Javed A. Antipsychotic medication and QT prolongation. Pak J Med Sci. 2015;31(5):1269–71. https://doi.org/10.12669/pjms.315.8998; Khasanova AK. Pharmacogenetic factors of clozapine-induced metabolic syndrome. Personalized Psychiatry and Neurology. 2023;3(2):38–47. https://doi.org/10.52667/2712-9179-2023-3-2-38-47; Giardin F, Gex-Fabry M, Berney P, Shah D, Gaspoz J, Dayer P. Drug-induced long QT in adult psychiatric inpatients: the 5-year cross-sectional ECG screening outcome in psychiatry study. Am J Psychiatry. 2013;170(12):1468–76. https://doi.org/10.1176/appi.ajp.2013.12060860; Акимова ЕС, Зиганшина ЛЕ, Лоранская ИД, Качан ВО, Клепикова МВ, Кочетков АИ и др. Лекарственно-индуцированные заболевания. М.: Прометей; 2022. EDN: SSCIYA; Lambiase PD, de Bono JP, Schilling RJ, Lowe M, Turley A, Slade A, et al. British Heart Rhythm Society Clinical practice guidelines on the management of patients developing QT prolongation on antipsychotic medication. Arrhythm Electrophysiol Rev. 2019;8(3):161–5. https://doi.org/10.15420/aer.2019.8.3.G1; Абриталин ЕЮ, Александровский ЮА, Ананьева НИ, Аничков АД, Ахапкин РВ, Букреева НД и др. Психиатрия: национальное руководство. М.: ГЭОТАР-Медиа; 2018. EDN: YMILDU; Gorobets LN, Semenova ND, Litvinov AV. Application of antipsychotic medication: gender differences in tolerance and medication response. Personalized Psychiatry and Neurology. 2022;2(2):57–66. https://doi.org/10.52667/2712-9179-2022-2-2-57-66; Zhou J, Zhu T, Zhu X, Galling B, Xiao L. Factors associated with antipsychotic use in non-psychotic depressed patients: results from a clinical multicenter survey. BMC Psychiatry. 2022;22(1):80. https://doi.org/10.1186/s12888-021-03411-y; Jha MK, Mathew SJ. Pharmacotherapies for treatment-resistant depression: how antipsychotics fit in the rapidly evolving therapeutic landscape. Am J Psychiatry. 2023;180(3):190–9. https://doi.org/10.1176/appi.ajp.20230025; Roessner V, Eichele H, Stern JS, Skov L, Rizzo R, Debes NM, et al. European clinical guidelines for Tourette syndrome and other tic disorders—version 2.0. Part III: pharmacological treatment. Eur Child Adolesc Psychiatry. 2022;31(3):425–41. https://doi.org/10.1007/s00787-021-01899-z; Leichsenring F, Heim N, Leweke F, Spitzer C, Steinert C, Kernberg OF. Borderline personality disorder: a review. JAMA. 2023;329(8):670–9. https://doi.org/10.1001/jama.2023.0589; Pascual JC, Arias L, Soler J. Pharmacological management of borderline personality disorder and common comorbidities. CNS Drugs. 2023;37:489–97. https://doi.org/10.1007/s40263-023-01015-6; Gomes T, Khuu W, Tadrous M, Vigod S, Cobigo V, Lunsky Y. Antipsychotic initiation among adults with intellectual and developmental disabilities in Ontario: a population-based cohort study. BMJ Open. 2019;9(7):e028125. https://doi.org/10.1136/bmjopen-2018-028125; Pompili M, Ducci G, Galluzzo A, Rosso G, Palumbo C, De Berardis D. The management of psychomotor agitation associated with schizophrenia or bipolar disorder: a brief review. Int J Environ Res Public Health. 2021;18(8):4368. https://doi.org/10.3390/ijerph18084368; Zareifopoulos N, Panayiotakopoulos G. Treatment options for acute agitation in psychiatric patients: theoretical and empirical evidence. Cureus. 2019;11(11):e6152. https://doi.org/10.7759/cureus.6152; Orzelska-Górka J, Mikulska J, Wiszniewska A, Biała G. New atypical antipsychotics in the treatment of schizophrenia and depression. Int J Mol Sci. 2022;23(18):10624. https://doi.org/10.3390/ijms231810624; MacKenzie NE, Kowalchuk C, Agarwal SM, Costa-Dookhan KA, Caravaggio F, Gerretsen P, et al. Antipsychotics, metabolic adverse effects, and cognitive function in schizophrenia. Front Psychiatry. 2018;9:622. https://doi.org/10.3389/fpsyt.2018.00622; Wunderink L. Personalizing antipsychotic treatment: evidence and thoughts on individualized tailoring of antipsychotic dosage in the treatment of psychotic disorders. Ther Adv Psychopharmacol. 2019;9:2045125319836566. https://doi.org/10.1177/2045125319836566; Остроумова ОД, Голобородова ИВ. Лекарственно-индуцированное удлинение интервала QT: распространенность, факторы риска, лечение и профилактика. Consilium Medicum. 2019;21(5):62–7. https://doi.org/10.26442/20751753.2019.5.190415; Волков ВП. Кардиотоксичность антипсихотических препаратов. Тверь: Триада; 2018. EDN: YMHBSX; Волков ВП. Нейролептическая кардиомиопатия. Тверь: Триада; 2020. EDN: TKMHCF; Friedrich ME, Winkler D, Konstantinidis A, Huf W, Engel R, Toto S, et al. Cardiovascular adverse reactions during antipsychotic treatment: results of AMSP, a drug surveillance program between 1993 and 2013. Int J Neuropsychopharmacol. 2020;23(2):67–75. https://doi.org/10.1093/ijnp/pyz046; Shnayder NA, Kidyaeva AV, Vaiman EE, Asadullin AR, Petrova MM, Kaskaeva DS, et al. Role of pharmacokinetics and pharmacogenetics of antidepressant-induced prolongation of the QT interval and Torsade de Pointes in patients with mental disorders. Personalized Psychiatry and Neurology. 2023;3(2):72–119. https://doi.org/10.52667/2712-9179-2023-3-2-72-119; Vandenberk B, Vandael E, Robyns T, Vandenberghe J, Garweg C, Foulon V, et al. Which QT correction formulae to use for QT monitoring? J Am Heart Assoc. 2016;5(6):e003264. https://doi.org/10.1161/JAHA.116.003264; Drew BJ, Ackerman MJ, Funk M, Gibler WB, Kligfield P, Menon V, et al. Prevention of Torsade de Pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. Circulation. 2010;121(8):1047–60. https://doi.org/10.1161/CIRCULATIONAHA.109.192704; Khatib R, Sabir FRN, Omari C, Pepper C, Tayebjee MH. Managing drug-induced QT prolongation in clinical practice. Postgrad Med J. 2021;97(1149):452–8. https://doi.org/10.1136/postgradmedj-2020-138661; Rochester MP, Kane AM, Linnebur SA, Fixen DR. Evaluating the risk of QTc prolongation associated with antidepressant use in older adults: a review of the evidence. Ther Adv Drug Saf. 2018;9(6):297–308. https://doi.org/10.1177/2042098618772979; Salvati B, Miola A, Toffanin T, Pigato G, Pavan C, Favaro A, et al. Prevalence and risk factors for QTc prolongation in acute psychiatric hospitalization. Prim Care Companion CNS Disord. 2022;24(1):21m02915. https://doi.org/10.4088/PCC.21m02915; Christensen L, Turner JR, Peterson GM, Naunton M, Thomas J, Yee KC, Kosari S. Identification of risk of QT prolongation by pharmacists when conducting medication reviews in residential aged care settings: a missed opportunity? J Clin Med. 2019;8(11):1866. https://doi.org/10.3390/jcm8111866; Danielsson B, Collin J, Nyman A, Bergendal A, Borg N, State M, et al. Drug use and torsades de pointes cardiac arrhythmias in Sweden: a nationwide register-based cohort study. BMJ Open. 2020;10(3):e034560. https://doi.org/10.1136/bmjopen-2019-034560; Salem JE, Dureau P, Bachelot A, Germain M, Voiriot P, Lebourgeois B, et al. Association of oral contraceptives with drug-induced QT interval prolongation in healthy nonmenopausal women. JAMA Cardiol. 2018;3(9):877–82. https://doi.org/10.1001/jamacardio.2018.2251; Li M, Ramos LG. Drug-induced QT prolongation and Torsades de Pointes. P T. 2017;42(7):473–7. PMID: 28674475; Iribarren C, Round AD, Peng JA, Lu M, Zaroff JG, Holve TJ, et al. Validation of a population-based method to assess drug-induced alterations in the QT interval: a self-controlled crossover study. Pharmacoepidemiol Drug Saf. 2013;22(11):1222–32. https://doi.org/10.1002/pds.3479; Hanna MP, Adie SK, Ketcham SW, Deshmukh A, Gondi K, Abdul-Aziz AA, et al. Atypical antipsychotic safety in the CICU. Am J Cardiol. 2022;163:117–23. https://doi.org/10.1016/j.amjcard.2021.09.052; Mizuki Y, Takaki M. Blonanserin ameliorated the tendency toward QTc prolongation associated with risperidone in a patient with schizophrenia. J Clin Psychopharmacol. 2015;35(1):101–2. https://doi.org/10.1097/JCP.0000000000000267; Kambayashi R, Hagiwara-Nagasawa M, Goto A, Chiba K, Izumi-Nakaseko H, Naito AT, et al. Experimental analysis of the onset mechanism of TdP reported in an LQT3 patient during pharmacological treatment with serotonin-dopamine antagonists against insomnia and nocturnal delirium. Heart Vessels. 2020;35(4):593–602. https://doi.org/10.1007/s00380-019-01521-y; Xiang YT, Chiu HF, Ungvari GS, Correll CU, Lai KY, Wang CY, et al. QTc prolongation in schizophrenia patients in Asia: clinical correlates and trends between 2004 and 2008/2009. Hum Psychopharmacol. 2015;30(2):94–9. https://doi.org/10.1002/hup.2458; Berling I, Isbister GK. Prolonged QT risk assessment in antipsychotic overdose using the QT nomogram. Ann Emerg Med. 2015;66(2):154–64. https://doi.org/10.1016/j.annemergmed.2014.12.005; Raschi E, Poluzzi E, Salvo F, Koci A, Suling M, Antoniazzi S, et al. The contribution of national spontaneous reporting systems to detect signals of torsadogenicity: issues emerging from the ARITMO project. Drug Saf. 2016;39(1):59–68. https://doi.org/10.1007/s40264-015-0353-1; Tariot PN, Cummings JL, Soto-Martin ME, Ballard C, Erten-Lyons D, Sultzer DL, et al. Trial of pimavanserin in dementia-related psychosis. N Engl J Med. 2021;385(4):309–19. https://doi.org/10.1056/NEJMoa2034634; Nielsen J, Wang F, Graff C, Kanters JK. QT dynamics during treatment with sertindole. Ther Adv Psychopharmacol. 2015;5(1):26–31. https://doi.org/10.1177/2045125314560738; Campleman SL, Brent J, Pizon AF, Shulman J, Wax P, Manini AF; Toxicology Investigators’ Consortium (ToxIC). Drug-specific risk of severe QT prolongation following acute drug overdose. Clin Toxicol (Phila). 2020;58(12):1326–34. https://doi.org/10.1080/15563650.2020.1746330; Pereira L, Budovich A, Claudio-Saez M. Monitoring of metabolic adverse effects associated with atypical antipsychotic use in an outpatient psychiatric clinic. J Pharm Pract. 2018;32:1–6. https://doi.org/10.1177/0897190017752712; Sicouri S, Antzelevitch C. Mechanisms underlying the actions of antidepressant and antipsychotic drugs that cause sudden cardiac arrest. Arrhythm Electrophysiol Rev. 2018;7(3):199–209. https://doi.org/10.15420/aer.2018.29.2; Bordet C, Garcia P, Salvo F, Touafchia A, Galinier M, Sommet A, Montastruc F. Antipsychotics and risk of QT prolongation: a pharmacovigilance study. Psychopharmacology (Berl). 2023;240(1):199–202. https://doi.org/10.1007/s00213-022-06293-4; Yap YG, Camm AJ. Drug induced QT prolongation and Torsades de Pointes. Heart. 2003;89(11):1363–72. https://doi.org/10.1136/heart.89.11.1363; Hasnain M, Vieweg WV, Howland RH, Kogut C, Breden Crouse EL, Koneru JN, et al. Quetiapine and the need for a thorough QT/QTc study. J Clin Psychopharmacol. 2014;34(1):3–6. https://doi.org/10.1097/JCP.0000000000000075; Duncan RS, McPate MJ, Ridley JM, Gao Z, James AF, Leishman DJ, et al. Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin. Biochem Pharmacol. 2007;74(3):425–37. https://doi.org/10.1016/j.bcp.2007.04.024; Naksuk N, Thongprayoon C, Park JY, Sharma S, Gaba P, Rosenbaum AN, et al. Editor’s choice-clinical impact of delirium and antipsychotic therapy: 10-year experience from a referral coronary care unit. Eur Heart J Acute Cardiovasc Care. 2017;6(6):560–8. https://doi.org/10.1177/2048872615592232; Beach SR, Celano CM, Sugrue AM, Adams C, Ackerman MJ, Noseworthy PA, Huffman JC. QT prolongation, Torsades de Pointes, and psychotropic medications: a five year update. Psychosomatics. 2018;59(2):105–22. https://doi.org/10.1016/j.psym.2017.10.009; Schmidt A, Fischer P, Wally B, Scharfetter J. Influence of intravenous administration of the antipsychotic drug benperidol on the QT interval. Neuropsychiatr. 2017;31(4):172–5. https://doi.org/10.1007/s40211-017-0230-5; Zhu MH, Liu ZJ, Hu QY, Yang JY, Jin Y, Zhu N, et al. Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled trial. Mil Med Res. 2022;9(1):59. https://doi.org/10.1186/s40779-022-00420-0; Aronow WS, Shamliyan TA. Effects of atypical antipsychotic drugs on QT interval in patients with mental disorders. Ann Transl Med. 2018;6(8):147. https://doi.org/10.21037/atm.2018.03.17; Zhuravlev NM, Shnayder NA, Vaiman EE, Abdyrakhmanova AK, Petrova MM, Bochanova EN, et al. Interindividual variability of anticonvulsant-induced QT prolongation risk. Personalized Psychiatry and Neurology. 2022;1(2):22–45. https://doi.org/10.52667/2712-9179-2022-2-1-23-45; Iwata N, Ishigooka J, Naoi I, Matsumoto M, Kanamori Y, Nakamura H, Higuchi T. Long-term safety and efficacy of blonanserin transdermal patches in Japanese patients with schizophrenia: a 52-week open-label, multicenter study. CNS Drugs. 2020;34(1):103–16. https://doi.org/10.1007/s40263-019-00692-6; Kane JM, Peters-Strickland T, Baker RA, Hertel P, Eramo A, Jin N, et al. Aripiprazole once-monthly in the acute treatment of schizophrenia: findings from a 12-week, randomized, double-blind, placebo-controlled study. J Clin Psychiatry. 2014;75(11):1254–60. https://doi.org/10.4088/JCP.14m09168; Nasrallah HA, Aquila R, Du Y, Stanford AD, Claxton A, Weiden PJ. Long-term safety and tolerability of aripiprazole lauroxil in patients with schizophrenia. CNS Spectr. 2019;24(4):395–403. https://doi.org/10.1017/S1092852918001104; Pigott TA, Carson WH, Saha AR, Torbeyns AF, Stock EG, Ingenito GG; Aripiprazole Study Group. Aripiprazole for the prevention of relapse in stabilized patients with chronic schizophrenia: a placebo-controlled 26-week study. J Clin Psychiatry. 2003;64(9):1048–56. https://doi.org/10.4088/jcp.v64n0910; Kasper S, Lerman MN, McQuade RD, Saha A, Carson WH, Ali M, et al. Efficacy and safety of aripiprazole vs. haloperidol for long-term maintenance treatment following acute relapse of schizophrenia. Int J Neuropsychopharmacol. 2003;6(4):325–37. https://doi.org/10.1017/S1461145703003651; Bugarski-Kirola D, Bitter I, Liu IY, Abbs B, Stankovic S. ENHANCE: phase 3, randomized, double-blind, placebo-controlled study of adjunctive pimavanserin for schizophrenia in patients with an inadequate response to antipsychotic treatment. Schizophr Bull Open. 2022;3:sgac006. https://doi.org/10.1093/schizbullopen/sgac006; Bugarski-Kirola D, Arango C, Fava M, Nasrallah H, Liu IY, Abbs B, Stankovic S. Pimavanserin for negative symptoms of schizophrenia: results from the ADVANCE phase 2 randomised, placebo-controlled trial in North America and Europe. Lancet Psychiatry. 2022;9(1):46–58. https://doi.org/10.1016/S2215-0366(21)00386-2; Ozeki Y, Fujii K, Kurimoto N, Yamada N, Okawa M, Aoki T, et al. QTc prolongation and antipsy chotic medications in a sample of 1017 patients with schizo phrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2010;34(2):401–5. https://doi.org/10.1016/j.pnpbp.2010.01.008; Beach SR, Gross AF, Hartney KE, Taylor JB, Rundell JR. Intravenous haloperidol: a systematic review of side effects and recommendations for clinical use. Gen Hosp Psychiatry. 2020;67:42–50. https://doi.org/10.1016/j.genhosppsych.2020.08.008; Малин ДИ, Рывкин ПВ, Булатова ДР. Синдром удлиненного интервала QT при применении антипсихотических и антидепрессивных препаратов. Современная терапия психических расстройств. 2023;(2):48–56. https://doi.org/10.21265/PSYPH.2023.69.57.006; Hommers L, Scherf-Clavel M, Stempel R, Roth J, Falter M, Deckert J, et al. Antipsychotics in routine treatment are minor contributors to QT prolongation compared to genetics and age. J Psychopharmacol. 2021;35(9):1127–33. https://doi.org/10.1177/02698811211003477; Preda A, Shapiro BB. A safety evaluation of aripiprazole in the treatment of schizophrenia. Expert Opin Drug Saf. 2020;19(12):1529–38. https://doi.org/10.1080/14740338.2020.1832990; Beach SR, Celano CM, Noseworthy PA, Januzzi JL, Huffman JC. QTc prolongation, torsades de pointes, and psychotropic medications. Psychosomatics. 2013;54(1):1–13. https://doi.org/10.1016/j.psym.2012.11.001; Wu CS, Tsai YT, Tsai HJ. Antipsychotic drugs and the risk of ventricular arrhythmia and/or sudden cardiac death: a nation-wide case-crossover study. J Am Heart Assoc. 2015;4(2):e001568. https://doi.org/10.1161/JAHA.114.001568; Leucht S, Cipriani A, Spineli L, et al. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet. 2015;3:925–927. https://doi.org/10.1016/S0140-6736(13)60733-3; Carrà G, Crocamo C, Bartoli F, Lax A, Tremolada M, Lucii C, et al. First-generation antipsychotics and QTc: any role for mediating variables? Hum Psycho pharmacol. 2016;31(4):313–8. https://doi.org/10.1002/hup.2540; Silvestre JS, Prous JR. Comparative evaluation of hERG potassium channel blockade by antipsychotics. Methods Find Exp Clin Pharmacol. 2007;29(7):457–65. https://doi.org/10.1358/mf.2007.29.7.1119172; Lehmann DF, Eggleston WD, Wang D. Validation and clinical utility of the hERG IC 50 :C max ratio to determine the risk of drug-induced Torsades de Pointes: a meta-analysis. Pharmacotherapy. 2018;38(3):341–8. https://doi.org/10.1002/phar.2087; Tie H, Walker BD, Valenzuela SM, Breit SN, Campbell TJ. The heart of psychotropic drug therapy. Lancet. 2000;355(9217):1825. https://doi.org/10.1016/S0140-6736(05)73083-X; Le Marois M, Sanson C, Maizières MA, Partiseti M, Bohme GA. The atypic antipsychotic clozapine inhibits multiple cardiac ion channels. Naunyn Schmiedebergs Arch Pharmacol. 2023;396(1):161–6. https://doi.org/10.1007/s00210-022-02314-3; Lee HJ, Choi JS, Hahn SJ. Mechanism of inhibition by olanzapine of cloned hERG potassium channels. Neurosci Lett. 2015;609:97–102. https://doi.org/10.1016/j.neulet.2015.10.039; Lee HJ, Choi BH, Choi JS, Hahn SJ. Effects of iloperidone on hERG 1A/3.1 heterotetrameric channels. Neuroreport. 2021;32(16):1299–306. https://doi.org/10.1097/WNR.0000000000001724; Lee HJ, Choi JS, Choi BH, Hahn SJ. Inhibition of cloned hERG potassium channels by risperidone and paliperidone. Naunyn Schmiedebergs Arch Pharmacol. 2017;390(6):633–42. https://doi.org/10.1007/s00210-017-1364-5; Tamargo J. Drug-induced Torsade de Pointes: from molecular biology to bedside. Jpn J Pharmacol. 2000;83:1–19. https://doi.org/10.1254/jjp.83.1; https://www.risksafety.ru/jour/article/view/410

الاتاحة: https://www.risksafety.ru/jour/article/view/410
https://doi.org/10.30895/2312-7821-2024-410

المؤلفون: George M. Bodziock, Giselle C. Meléndez

المصدر: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

مصطلحات موضوعية: antracyclines, QT prolongation, monkeys, repolarization reserve, cardiomyopathy, Torsade de point, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2023.1247273/full; https://doaj.org/toc/2297-055X

URL الوصول: https://doaj.org/article/8f1a1cd00a184d7bb83a9083f4a37695