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1Academic Journal
المؤلفون: van Oosterwijk , Niels, Willies, Simon, Hekelaar, Johan, Terwisscha van Scheltinga, Anke C, Turner, Nicholas J, Dijkstra, Bauke W
المصدر: van Oosterwijk , N , Willies , S , Hekelaar , J , Terwisscha van Scheltinga , A C , Turner , N J & Dijkstra , B W 2016 , ' Structural Basis of the Substrate Range and Enantioselectivity of Two (S)-Selective ω-Transaminases ' , Biochemistry , vol. 55 , no. 31 , pp. 4422-4431 . https://doi.org/10.1021/acs.biochem.6b00370
مصطلحات موضوعية: Structural biology, enantioselectivity, (S)-Selective w-transaminases, enzymes, side-directed mutagenesis, PYRIDOXAL-PHOSPHATE ENZYMES, CHIRAL AMINES, ASYMMETRIC-SYNTHESIS, CRYSTAL-STRUCTURES, DATA QUALITY, COLI-CELLS, SPECIFICITY, AMINOTRANSFERASE, CRYSTALLOGRAPHY, REFINEMENT
وصف الملف: application/pdf
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2Academic Journal
المصدر: Wybenga , G G , Crismaru , C G , Janssen , D B & Dijkstra , B W 2012 , ' Structural Determinants of the beta-Selectivity of a Bacterial Aminotransferase ' , The Journal of Biological Chemistry , vol. 287 , no. 34 , pp. 28495-28502 . https://doi.org/10.1074/jbc.M112.375238
مصطلحات موضوعية: PYRIDOXAL-PHOSPHATE ENZYMES, AMINO-ACID AMINOTRANSFERASE, ASPARTATE-AMINOTRANSFERASE, CRYSTAL-STRUCTURES, DEPENDENT ENZYMES, SPATIAL STRUCTURE, ACTIVE-SITE, TRANSAMINASE, CRYSTALLOGRAPHY, SERVER
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/746cbe86-5305-4ffa-8993-8f36afdc55a9
https://research.rug.nl/en/publications/746cbe86-5305-4ffa-8993-8f36afdc55a9
https://doi.org/10.1074/jbc.M112.375238
https://pure.rug.nl/ws/files/6783538/2012JBiolChemWybengaSupp.pdf
https://pure.rug.nl/ws/files/6783539/2012JBiolChemWybenga.pdf -
3
المؤلفون: Niels van Oosterwijk, Simon C. Willies, Johan Hekelaar, Nicholas J. Turner, Bauke W. Dijkstra, Anke C. Terwisscha van Scheltinga
المساهمون: X-ray Crystallography
المصدر: Biochemistry, 55(31), 4422-4431. AMER CHEMICAL SOC
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, side-directed mutagenesis, Protein Conformation, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Substrate Specificity, chemistry.chemical_compound, Protein structure, Catalytic Domain, (S)-Selective w-transaminases, Side chain, Transferase, CRYSTAL-STRUCTURES, ASYMMETRIC-SYNTHESIS, SPECIFICITY, biology, REFINEMENT, CRYSTALLOGRAPHY, Stereoisomerism, Recombinant Proteins, Structural biology, DATA QUALITY, AMINOTRANSFERASE, Stereochemistry, enzymes, 03 medical and health sciences, Bacterial Proteins, CHIRAL AMINES, enantioselectivity, Carboxylate, Arthrobacter, Protein Structure, Quaternary, PYRIDOXAL-PHOSPHATE ENZYMES, Transaminases, 010405 organic chemistry, Active site, 0104 chemical sciences, Kinetics, 030104 developmental biology, Amino Acid Substitution, chemistry, Biocatalysis, Bacillus megaterium, Mutagenesis, Site-Directed, biology.protein, COLI-CELLS, Cysteine
وصف الملف: application/pdf
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4Dissertation/ Thesis
المؤلفون: Bharath, S R
Thesis Advisors: Murthy, M R N
مصطلحات موضوعية: Enzymes - Structure, D-Amino Acids - Metabolism, Amino Acid Stress Response, Pyridoxal Phosphate Enzymes, D-Serine Dehydratase Enzymes, D-Cysteine Desulfhydrase Enzymes, Arginine Decarboxylase Enzymes, Salmonella Typhimurium D-Serine Dehydratase, Salmonella Typhimurium D-Cysteine Desulfhydrase, Salmonella Typhimurium Arginine Decarboxylase, Pyridoxal Phosphate Enzymes - Structure, Pyridoxal 5′-phosphate, D-Serine Deaminase, Structural Biology
Relation: G25333
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5
المؤلفون: Hult, Karl, Berglund, Per
المصدر: Trends in Biotechnology. 25(5):231-238
مصطلحات موضوعية: catalyzed markovnikov addition, pyridoxal-phosphate enzymes, active-site mutation, enolase superfamily, michael addition, reaction specificity, mutant glycosidases, organic media, oligosaccharide synthesis, thioglycoside synthesis
وصف الملف: print
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6
المؤلفون: Suzanne B. Renwick, Keith Snell, Ulrich Baumann
المصدر: Structure. 6(9):1105-1116
مصطلحات موضوعية: DNA Replication, Models, Molecular, Protein Folding, Multiple isomorphous replacement, Protein Conformation, Stereochemistry, Molecular Sequence Data, Glycine, serine hydroxymethyltransferase, Biology, Crystallography, X-Ray, cancer chemotherapy, Serine, Cytosol, Protein structure, Structural Biology, Catalytic Domain, Neoplasms, Humans, Transferase, pyridoxal phosphate enzymes, Enzyme Inhibitors, Binding site, Molecular Biology, Tetrahydrofolates, X-ray crystallography, Glycine Hydroxymethyltransferase, chemistry.chemical_classification, Binding Sites, Active site, Recombinant Proteins, Enzyme, Models, Chemical, Biochemistry, chemistry, Drug Design, Serine hydroxymethyltransferase, biology.protein, Dimerization
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7Academic Journal
المؤلفون: Wadsworth, John M., Clarke, David J., McMahon, Stephen A., Lowther, Jonathan P., Beattie, Ashley E., Langridge-Smith, Pat R. R., Broughton, Howard B., Dunn, Teresa M., Naismith, James H., Campopiano, Dominic J.
المصدر: Wadsworth , J M , Clarke , D J , McMahon , S A , Lowther , J P , Beattie , A E , Langridge-Smith , P R R , Broughton , H B , Dunn , T M , Naismith , J H & Campopiano , D J 2013 , ' The chemical basis of serine palmitoyltransferase inhibition by myriocin ' , Journal of the American Chemical Society , vol. 135 , no. 38 , pp. 14276-14285 . https://doi.org/10.1021/ja4059876
مصطلحات موضوعية: PYRIDOXAL-PHOSPHATE ENZYMES, SPHINGOLIPID BIOSYNTHESIS, REACTION-MECHANISM, CRYSTAL-STRUCTURE, DRUG DISCOVERY, KEY ENZYME, AMINO-ACID, PROTEINS, CRYSTALLOGRAPHY, INACTIVATION
الاتاحة: https://risweb.st-andrews.ac.uk/portal/en/researchoutput/the-chemical-basis-of-serine-palmitoyltransferase-inhibition-by-myriocin(b1e3f082-2632-4f61-8e98-dbfd52b9f06d).html
https://doi.org/10.1021/ja4059876 -
8
المساهمون: X-ray Crystallography, Biotechnology
المصدر: The Journal of Biological Chemistry, 287(34), 28495-28502. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
مصطلحات موضوعية: TRANSAMINASE, Stereochemistry, Phenylalanine, Crystallography, X-Ray, Biochemistry, Transaminase, Substrate Specificity, chemistry.chemical_compound, DEPENDENT ENZYMES, Biosynthesis, AMINO-ACID AMINOTRANSFERASE, Transferase, CRYSTAL-STRUCTURES, Pyridoxal phosphate, Enzyme Inhibitors, PYRIDOXAL-PHOSPHATE ENZYMES, Molecular Biology, Pyridoxal, Transaminases, chemistry.chemical_classification, SERVER, Binding Sites, biology, ACTIVE-SITE, CRYSTALLOGRAPHY, Mesorhizobium, Active site, Cell Biology, equipment and supplies, ASPARTATE-AMINOTRANSFERASE, Amino acid, Protein Structure, Tertiary, Enantiopure drug, chemistry, Protein Structure and Folding, biology.protein, Ketoglutaric Acids, SPATIAL STRUCTURE
وصف الملف: application/pdf
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9Academic Journal
المؤلفون: Raman, Marine C. C., Johnson, Kenneth A., Yard, Beverley A., Lowther, Jonathan, Carter, Lester G., Naismith, James H., Campopiano, Dominic J.
المصدر: Raman , M C C , Johnson , K A , Yard , B A , Lowther , J , Carter , L G , Naismith , J H & Campopiano , D J 2009 , ' The External Aldimine Form of Serine Palmitoyltransferase STRUCTURAL, KINETIC, AND SPECTROSCOPIC ANALYSIS OF THE WILD-TYPE ENZYME AND HSAN1 MUTANT MIMICS ' , Journal of Biological Chemistry , vol. 284 , no. 25 , pp. 17328-17339 . https://doi.org/10.1074/jbc.M109.008680
مصطلحات موضوعية: HEREDITARY SENSORY NEUROPATHY, PYRIDOXAL-PHOSPHATE ENZYMES, 8-AMINO-7-OXONONANOATE SYNTHASE, SPHINGOLIPID SYNTHESIS, 5-AMINOLEVULINATE SYNTHASE, REACTION-MECHANISM, HEME-BIOSYNTHESIS, CRYSTAL-STRUCTURE, BASE SYNTHESIS, YEAST LCB1
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10Academic Journal
المؤلفون: Yard, Beverley A., Carter, Lester G., Johnson, Kenneth A., Overton, Ian M., Dorward, Mark, Liu, Huanting, McMahon, Stephen A., Oke, Muse, Puech, Daphne, Barton, Geoffrey J., Naismith, James H., Campopiano, Dominic J.
المصدر: Yard , B A , Carter , L G , Johnson , K A , Overton , I M , Dorward , M , Liu , H , McMahon , S A , Oke , M , Puech , D , Barton , G J , Naismith , J H & Campopiano , D J 2007 , ' The structure of serine palmitoyltransferase; Gateway to sphingolipid biosynthesis ' , Journal of Molecular Biology , vol. 370 , pp. 870-886 . https://doi.org/10.1016/j.jmb.2007.04.086
مصطلحات موضوعية: serine palmitoyltransferase, sphingolipids, X-ray crystallography, bioinformatics, hereditary sensory and autonomic neuropathy type I, HEREDITARY SENSORY NEUROPATHY, PYRIDOXAL-PHOSPHATE ENZYMES, 8-AMINO-7-OXONONANOATE SYNTHASE, SEQUENCE ALIGNMENT, CRYSTAL-STRUCTURE, 5-AMINOLEVULINATE SYNTHASE, SPHINGOMONAS-PAUCIMOBILIS, REACTION SPECIFICITY, HEME-BIOSYNTHESIS, BASE SYNTHESIS
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11Dissertation/ Thesis
المؤلفون: Bharath, S R
المساهمون: Murthy, M R N
مصطلحات موضوعية: Enzymes - Structure, D-Amino Acids - Metabolism, Amino Acid Stress Response, Pyridoxal Phosphate Enzymes, D-Serine Dehydratase Enzymes, D-Cysteine Desulfhydrase Enzymes, Arginine Decarboxylase Enzymes, Salmonella Typhimurium D-Serine Dehydratase, Salmonella Typhimurium D-Cysteine Desulfhydrase, Salmonella Typhimurium Arginine Decarboxylase, Pyridoxal Phosphate Enzymes - Structure, Pyridoxal 5′-phosphate, D-Serine Deaminase, Structural Biology
وصف الملف: application/pdf
Relation: G25333; http://etd.iisc.ac.in/handle/2005/2476; http://etd.iisc.ac.in/static/etd/abstracts/3195/G25333-Abs.pdf