نتائج البحث - "Pybus, Leon P"

1

Academic Journal

Dissecting cell death pathways in fed-batch bioreactors

المؤلفون: Mentlak, David A, Raven, John, Moses, Tessa, Massie, Fraser, Barber, Nicholas, Hoare, Robyn, Burton, Graeme, Young, Alison, Pybus, Leon P, Rosser, Susan, White, Robert J, Ungar, Daniel, Bryant, Nia J

وصف الملف: text

Relation: https://eprints.whiterose.ac.uk/207818/1/Biotechnology_Journal_-_2023_-_Mentlak_-_Dissecting_cell_death_pathways_in_fed_batch_bioreactors.pdf; Mentlak, David A, Raven, John, Moses, Tessa et al. (10 more authors) (2024) Dissecting cell death pathways in fed-batch bioreactors. Biotechnology journal. 2300257. ISSN 1860-7314

الاتاحة: https://eprints.whiterose.ac.uk/207818/
https://doi.org/10.1002/biot.202300257

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2

Academic Journal

Use of tRNA gene barriers improves stability of transgene expression in CHO cells

المؤلفون: Sizer, Rebecca E., Ingram, Richard M., Swan, Caroline, Biggs, Emma K., Pybus, Leon P., White, Robert J.

المصدر: Biotechnology Journal ; volume 19, issue 8 ; ISSN 1860-6768 1860-7314

الاتاحة: http://dx.doi.org/10.1002/biot.202400196

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3

Academic Journal

A modular and multi‐functional purification strategy that enables a common framework for manufacturing scale integrated and continuous biomanufacturing

المؤلفون: Pybus, Leon P., Heise, Charles, Nagy, Tibor, Heeran, Carmen, Dover, Terri, Raven, John, Kori, Junichi, Burton, Graeme, Sakuyama, Hiroshi, Hastings, Benjamin, Lyons, Michelle, Nakai, Shinichi, Haigh, Jonathan

المصدر: Biotechnology Progress ; volume 40, issue 4 ; ISSN 8756-7938 1520-6033

الاتاحة: http://dx.doi.org/10.1002/btpr.3456

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4

Academic Journal

Deciphering molecular drivers of lactate metabolic shift in mammalian cell cultures

المؤلفون: Torres, Mauro, Hawke, Ellie, Hoare, Robyn, Scholey, Rachel, Pybus, Leon P., Young, Alison, Hayes, Andrew, Dickson, Alan J.

المصدر: Metabolic Engineering ; ISSN 1096-7176

الاتاحة: https://doi.org/10.1016/j.ymben.2024.12.001
https://api.elsevier.com/content/article/PII:S1096717624001642?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1096717624001642?httpAccept=text/plain

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5

Dissertation/ Thesis

Engineering the expression of 'difficult-to-express' recombinant monoclonal antibodies in Chinese hamster ovary cells

المؤلفون: Pybus, Leon P.

Thesis Advisors: James, David C.

مصطلحات موضوعية: 660

الاتاحة: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617212

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6

Academic Journal

Dissecting cell death pathways in fed‐batch bioreactors.

المؤلفون: Mentlak, David A., Raven, John, Moses, Tessa, Massie, Fraser, Barber, Nicholas, Hoare, Robyn, Burton, Graeme, Young, Alison, Pybus, Leon P., Rosser, Susan, White, Robert J., Ungar, Daniel, Bryant, Nia J.

المصدر: Biotechnology Journal; Jan2024, Vol. 19 Issue 1, p1-12, 12p

7

Academic Journal

Coupling picodroplet microfluidics with plate imaging for the rapid creation of biomanufacturing suitable cell lines with high probability and improved multi‐step assurance of monoclonality

المؤلفون: Pybus, Leon P., Kalsi, Devika, Matthews, Joe T., Hawke, Ellie, Barber, Nicholas, Richer, Rachel, Young, Alison, Saunders, Fay L.

المصدر: Biotechnology Journal ; volume 17, issue 1 ; ISSN 1860-6768 1860-7314

الاتاحة: http://dx.doi.org/10.1002/biot.202100357
https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.202100357
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/biot.202100357

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8

Academic Journal

Coupling picodroplet microfluidics with plate imaging for the rapid creation of biomanufacturing suitable cell lines with high probability and improved multi‐step assurance of monoclonality.

المؤلفون: Pybus, Leon P., Kalsi, Devika, Matthews, Joe T., Hawke, Ellie, Barber, Nicholas, Richer, Rachel, Young, Alison, Saunders, Fay L.

المصدر: Biotechnology Journal; Jan2022, Vol. 17 Issue 1, p1-7, 7p

9

Academic Journal

Scale‐Down Model Development in ambr systems: An Industrial Perspective

المؤلفون: Sandner, Viktor, Pybus, Leon P., McCreath, Graham, Glassey, Jarka

المساهمون: H2020 Marie Skłodowska-Curie Actions

المصدر: Biotechnology Journal ; volume 14, issue 4 ; ISSN 1860-6768 1860-7314

الاتاحة: http://dx.doi.org/10.1002/biot.201700766
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbiot.201700766
https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.201700766
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/biot.201700766

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10

Academic Journal

Model‐directed engineering of “difficult‐to‐express” monoclonal antibody production by Chinese hamster ovary cells

المؤلفون: Pybus, Leon P., Dean, Greg, West, Nathan R., Smith, Andrew, Daramola, Olalekan, Field, Ray, Wilkinson, Stephen J., James, David C.

المساهمون: Biotechnology and Biological Sciences Research Council

المصدر: Biotechnology and Bioengineering ; volume 111, issue 2, page 372-385 ; ISSN 0006-3592 1097-0290

الاتاحة: http://dx.doi.org/10.1002/bit.25116
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbit.25116
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.25116

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11

Academic Journal

An empirical modeling platform to evaluate the relative control discrete CHO cell synthetic processes exert over recombinant monoclonal antibody production process titer

المؤلفون: McLeod, Jane, O'Callaghan, Peter M., Pybus, Leon P., Wilkinson, Stephen J., Root, Tracy, Racher, Andrew J., James, David C.

المصدر: Biotechnology and Bioengineering ; volume 108, issue 9, page 2193-2204 ; ISSN 0006-3592 1097-0290

الاتاحة: http://dx.doi.org/10.1002/bit.23146
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbit.23146
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.23146

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12

Academic Journal

Impact of gene vector design on the control of recombinant monoclonal antibody production by chinese hamster ovary cells

المؤلفون: Davies, Sarah L., O'Callaghan, Peter M., McLeod, Jane, Pybus, Leon P., Sung, Yun Hee, Rance, James, Wilkinson, Stephen J., Racher, Andrew J., Young, Robert J., James, David C.

المصدر: Biotechnology Progress ; volume 27, issue 6, page 1689-1699 ; ISSN 8756-7938 1520-6033

الاتاحة: http://dx.doi.org/10.1002/btpr.692
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbtpr.692
http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.692/fullpdf

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13

Academic Journal

Cell line‐specific control of recombinant monoclonal antibody production by CHO cells

المؤلفون: O'Callaghan, Peter M., McLeod, Jane, Pybus, Leon P., Lovelady, Clare S., Wilkinson, Stephen J., Racher, Andrew J., Porter, Alison, James, David C.

المصدر: Biotechnology and Bioengineering ; volume 106, issue 6, page 938-951 ; ISSN 0006-3592 1097-0290

الاتاحة: http://dx.doi.org/10.1002/bit.22769
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbit.22769
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.22769

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14

Academic Journal

Model- directed engineering of 'difficult-to- express' monoclonal antibody production by Chinese hamster ovary cells.

المؤلفون: Pybus, Leon P., Dean, Greg, West, Nathan R., Smith, Andrew, Daramola, Olalekan, Field, Ray, Wilkinson, Stephen J., James, David C.

المصدر: Biotechnology & Bioengineering; Feb2014, Vol. 111 Issue 2, p372-385, 14p

15

Academic Journal

Predicting the expression of recombinant monoclonal antibodies in Chinese hamster ovary cells based on sequence features of the CDR3 domain.

المؤلفون: Pybus, Leon P., James, David C., Dean, Greg, Slidel, Tim, Hardman, Colin, Smith, Andrew, Daramola, Olalekan, Field, Ray

المصدر: Biotechnology Progress; Jan2014, Vol. 30 Issue 1, p188-197, 10p

مصطلحات موضوعية: GENE expression, MONOCLONAL antibodies, RECOMBINANT proteins, AMINO acid sequence, CELL culture, HAMSTERS as laboratory animals, BIOINFORMATICS

16

Academic Journal

Scale‐Down Model Development in ambr systems: An Industrial Perspective.

المؤلفون: Sandner, Viktor, Pybus, Leon P., McCreath, Graham, Glassey, Jarka

المصدر: Biotechnology Journal; Apr2019, Vol. 14 Issue 4, pN.PAG-N.PAG, 1p

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