المؤلفون: Chunhui Huang, Christian Fischer, Michelle R. Machacek, Stephane Bogen, Tesfaye Biftu, Xianhai Huang, Michael H. Reutershan, Ryan Otte, Qingmei Hong, Zhicai Wu, Yang Yu, Min Park, Lei Chen, Purakkattle Biju, Ian Knemeyer, Ping Lu, Christopher J. Kochansky, Michael Brendan Hicks, Yong Liu, Roy Helmy, Xavier Fradera, Anthony Donofrio, Josh Close, Matthew L. Maddess, Catherine White, David L. Sloman, Nunzio Sciammetta, Jun Lu, Craig Gibeau, Vladimir Simov, Hongjun Zhang, Peter Fuller, David Witter

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ecfd534a4182e5c705a82b16c3ffcc
https://europepmc.org/articles/PMC9014435/

المؤلفون: Craig C. Correll, Robert G. Aslanian, Li Xiao, Rema Bitar, Wei Zhou, John W. Butcher, Charles G. Garlisi, Joshua Close, Rachel N. Maccoss, Joon Jung, Scott Crawford, Kevin M. Maloney, Purakkattle Biju, Anandan Palani, Xianhai Huang, Xiaoxin Yang, Kevin D. McCormick, Scott Peterson, Hongjun Zhang, Diane Rindgen, Ying Huang, Alexei V. Buevich, Ning Shao, Li Dong, Phieng Siliphaivanh, Jason D. Brubaker, Michelle Martinez, Hongchen Qiu, François G. Gervais, Ravi P. Nargund, Zhidan Liu

المصدر: ACS Medicinal Chemistry Letters. 9:679-684

مصطلحات موضوعية: 0301 basic medicine, Drug, chemistry.chemical_classification, 010405 organic chemistry, Chemistry, medicine.drug_class, media_common.quotation_subject, Organic Chemistry, Pharmacology, medicine.disease, Receptor antagonist, 01 natural sciences, Biochemistry, 0104 chemical sciences, 03 medical and health sciences, 030104 developmental biology, Pharmacokinetics, Drug Discovery, medicine, Antagonism, Crth2 antagonist, Receptor, media_common, Asthma, Tricyclic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efda955acd4eb892808b6d65e2545f5
https://doi.org/10.1021/acsmedchemlett.8b00145

المؤلفون: Chao, Jianhua, Taveras, Arthur G., Chao, Jianping, Aki, Cynthia, Dwyer, Michael, Yu, Younong, Purakkattle, Biju, Rindgen, Diane, Jakway, James, Hipkin, William, Fosetta, James, Fan, Xuedong, Lundell, Daniel, Fine, Jay, Minnicozzi, Michael, Phillips, Jonathan, Merritt, J. Robert

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 17, issue 13, page 3778-3783 ; ISSN 0960-894X

الاتاحة: https://doi.org/10.1016/j.bmcl.2007.04.016
https://api.elsevier.com/content/article/PII:S0960894X07004428?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X07004428?httpAccept=text/plain

المؤلفون: Purakkattle Biju, Yeon-Hee Lim, Kevin D. McCormick, Michael Berlin, Ying Wang, Rema Bitar, Robert G. Aslanian

المصدر: Tetrahedron Letters. 56:636-638

مصطلحات موضوعية: Ring-closing metathesis, Stereochemistry, medicine.drug_class, Chemistry, Organic Chemistry, Drug Discovery, medicine, Prednisolone, Biochemistry, Anti-inflammatory, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::24281fd709bbb42be8f1e0ea2125cce6
https://doi.org/10.1016/j.tetlet.2014.12.048

المؤلفون: Rema Bitar, John C. Anthes, Jonathan E. Phillips, Purakkattle Biju, Robert G. Aslanian, Aileen House, Michael Berlin, Stephen Eckel, Daniel M. Solomon, George Kelly, Robbie L. McLeod, Richard Chapman, Xiomara Fernandez, Michelle Natiello, Daniel Prelusky, Kevin D. McCormick

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:6343-6347

مصطلحات موضوعية: medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Cell Line, Steroid, Structure-Activity Relationship, Transactivation, chemistry.chemical_compound, Therapeutic index, Administration, Inhalation, Drug Discovery, medicine, Animals, Structure–activity relationship, Sulfhydryl Compounds, Lung, Molecular Biology, Transrepression, Chemistry, Organic Chemistry, Asthma, In vitro, Rats, Benzothiazole, Cell culture, Molecular Medicine, Steroids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea94f04fce9e8206ef5e2b21f1f0210
https://doi.org/10.1016/j.bmcl.2011.08.108

المؤلفون: Zhou, Gang, Aslanian, Robert, Gallo, Gioconda, Khan, Tanweer, Kuang, Rongze, Purakkattle, Biju, Ruiz, Manuel De, Stamford, Andrew, Ting, Pauline, Wu, Heping, Wang, Hongwu, Xiao, Dong, Yu, Tao, Zhang, Yonglian, Mullins, Deborra, Hodgson, Robert

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 26, issue 4, page 1348-1354 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2015.11.048
https://api.elsevier.com/content/article/PII:S0960894X15302560?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0960894X15302560?httpAccept=text/xml

المؤلفون: X. Fernandez, Kevin D. McCormick, Johanna Jimenez, Hongwu Wang, Daniel Prelusky, Rema Bitar, Robert G. Aslanian, Yoon Joo Lee, Robbie L. McLeod, Gissela Lieber, Yanlin Jia, Richard Chapman, Steve Eckel, Michael Berlin, Purakkattle Biju, Yeon-Hee Lim, John C. Anthes, Jonathan E. Phillips, Aileen House

المصدر: Bioorganicmedicinal chemistry letters. 22(9)

مصطلحات موضوعية: Transcriptional Activation, Hydrocortisone, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Pyrazole, Sulfides, Ring (chemistry), Biochemistry, Transactivation, chemistry.chemical_compound, Structure-Activity Relationship, Quinoxaline, Glucocorticoid receptor, Receptors, Glucocorticoid, Thioether, Drug Discovery, Structure–activity relationship, Humans, Molecular Biology, Transrepression, Organic Chemistry, chemistry, Molecular Medicine, Pyrazoles, Steroids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734896b8e888c45b76a20dc076b65584
https://pubmed.ncbi.nlm.nih.gov/22465636

المؤلفون: Jonathan E. Phillips, Yanlin Jia, Gissela Lieber, Daniel Prelusky, Rema Bitar, Stephen Eckel, George Kelly, Purakkattle Biju, Michael Berlin, Johanna Jimenez, Richard Chapman, John C. Anthes, Hongwu Wang, Robbie L. McLeod, Daniel M. Solomon, Aileen House, Yoon Joo Lee, X. Fernandez, Robert G. Aslanian, Kevin D. McCormick

المصدر: Bioorganicmedicinal chemistry letters. 22(2)

مصطلحات موضوعية: Functional assay, Benzimidazole, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Administration, Oral, Biological Availability, Pharmacology, Sulfides, Biochemistry, Cell Line, chemistry.chemical_compound, Transactivation, Structure-Activity Relationship, Glucocorticoid receptor, Receptors, Glucocorticoid, Thioether, Rats, Inbred BN, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Transrepression, Tyrosine Transaminase, Dose-Response Relationship, Drug, Organic Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Stereoisomerism, Hep G2 Cells, Bioavailability, Rats, chemistry, Prednisolone, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51624800d0c54378487d97bd0d9250d
https://pubmed.ncbi.nlm.nih.gov/22197391

المؤلفون: Yu, Younong, Dwyer, Michael P., Chao, Jianping, Aki, Cynthia, Chao, Jianhua, Purakkattle, Biju, Rindgen, Diane, Bond, Richard, Mayer-Ezel, Rosemary, Jakway, James, Qiu, Hongchen, Hipkin, R. William, Fossetta, James, Gonsiorek, Waldemar, Bian, Hong, Fan, Xuedong, Terminelli, Carol, Fine, Jay, Lundell, Daniel, Merritt, J. Robert, He, Zhenmin, Lai, Gaifa, Wu, Minglang, Taveras, Arthur

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 18, issue 4, page 1318-1322 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2008.01.024
https://api.elsevier.com/content/article/PII:S0960894X08000383?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X08000383?httpAccept=text/plain