المؤلفون: Ninyio, Nathaniel, 1985, Schmitt, Katherina, Sergon, Gladys, 1984, Nilsson, Charlotta, Andersson, Sören, 1957, Scherbak, Nikolai, 1967

المصدر: Microbial Cell Factories. 23(1)

مصطلحات موضوعية: CRISPR/Cas9, HIV-1, Membrane-proximal external region (MPER), Outer membrane protein F (OmpF), Probiotic

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-111380
https://doi.org/10.1186/s12934-023-02290-0
https://oru.diva-portal.org/smash/get/diva2:1834578/FULLTEXT01.pdf

المؤلفون: Scheepers, Cathrine, Kgagudi, Prudence, Mzindle, Nonkululeko, Gray, Elin S., Moyo-Gwete, Thandeka, Lambson, Bronwen E., Oosthuysen, Brent, Mabvakure, Batsirai, Garrett, Nigel J., Karim, Salim S.Abdool, Morris, Lynn, Moore, Penny L.

المصدر: Research outputs 2022 to 2026

مصطلحات موضوعية: antibodies (bNAbs), membrane-proximal external region (MPER), HIV, virus, Germline-targeting immunogens, Diseases, Medicine and Health Sciences, Virus Diseases

وصف الملف: application/pdf

Relation: https://ro.ecu.edu.au/ecuworks2022-2026/1258; https://ro.ecu.edu.au/cgi/viewcontent.cgi?article=2258&context=ecuworks2022-2026

الاتاحة: https://ro.ecu.edu.au/ecuworks2022-2026/1258
https://ro.ecu.edu.au/cgi/viewcontent.cgi?article=2258&context=ecuworks2022-2026

المؤلفون: Gach, Johannes S, Achenbach, Chad J, Chromikova, Veronika, Berzins, Baiba, Lambert, Nina, Landucci, Gary, Forthal, Donald N, Katlama, Christine, Jung, Barbara H, Murphy, Robert L, Paxton, William A

المصدر: PLoS ONE. 9(1)

مصطلحات موضوعية: immunodeficiency-virus type-1, proximal external region, b-cell responses, potent neutralization, envelope glycoprotein, disease progression, elite suppressors, immune-responses, vaccine target, c infection

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8338q5nn

المؤلفون: Gach, Johannes S, Quendler, Heribert, Tong, Tommy, Narayan, Kristin M, Du, Sean X, Whalen, Robert G, Binley, James M, Forthal, Donald N, Poignard, Pascal, Zwick, Michael B, Pöhlmann, Stefan

المصدر: PLoS ONE. 8(8)

مصطلحات موضوعية: Immunodeficiency-Virus Type-1, Human Monoclonal-Antibodies, Proximal External Region, Immunoglobulin G1 B12, Envelope Glycoprotein, Vaccine Design, Particles Bearing, Structural Basis, Cell Responses, Recognition

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7v53r5np

المؤلفون: A. Andrianov M., A. Yushkevich M., I. Bosko P., A. Karpenko D., Yu. Kornoushenko V., K. Furs V., A. Tuzikov V., А. Андрианов М., А. Юшкевич М., И. Босько П., А. Карпенко Д., Ю. Корноушенко В., К. Фурс В., А. Тузиков В.

المصدر: Doklady of the National Academy of Sciences of Belarus; Том 65, № 6 (2021); 680-691 ; Доклады Национальной академии наук Беларуси; Том 65, № 6 (2021); 680-691 ; 2524-2431 ; 1561-8323 ; 10.29235/1561-8323-2021-65-6

مصطلحات موضوعية: HIV-1, gp41 protein, Membrane-Proximal External Region, HIV fusion inhibitors, molecular modeling, antiviral drugs, ВИЧ-1, белок gp41, мембрано-проксимальная внешняя область, ингибиторы слияния ВИЧ, клик-химия, молекулярное моделирование, противовирусные препараты

وصف الملف: application/pdf

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الاتاحة: https://doklady.belnauka.by/jour/article/view/1020
https://doi.org/10.29235/1561-8323-2021-65-6-680-691

المؤلفون: Young D. Kwon, Gwo-Yu Chuang, Baoshan Zhang, Robert T. Bailer, Nicole A. Doria-Rose, Tatyana S. Gindin, Bob Lin, Mark K. Louder, Krisha McKee, Sijy O’Dell, Amarendra Pegu, Stephen D. Schmidt, Mangaiarkarasi Asokan, Xuejun Chen, Misook Choe, Ivelin S. Georgiev, Vivian Jin, Marie Pancera, Reda Rawi, Keyun Wang, Rajoshi Chaudhuri, Lisa A. Kueltzo, Slobodanka D. Manceva, John-Paul Todd, Diana G. Scorpio, Mikyung Kim, Ellis L. Reinherz, Kshitij Wagh, Bette M. Korber, Mark Connors, Lawrence Shapiro, John R. Mascola, Peter D. Kwong

المصدر: Cell Reports, Vol 22, Iss 7, Pp 1798-1809 (2018)

مصطلحات موضوعية: antibody improvement, surface-matrix screening, HIV-1, broadly neutralizing antibody, membrane-proximal external region, MPER, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124718300408; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/20803a2ba97341ed985e9c54c91c448e

المؤلفون: Stefania Castelletto, Alberto Boretti

مصطلحات موضوعية: Biomedical imaging, Biomedical instrumentation, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), broadly neutralizing antibodies (bnABs), fluorescence, fluorescence super-resolution (FSR), green fluorescent protein (GFP), imaging, infection, membrane-proximal external region (MPER), microscopy, photo-activation localization microscopy (PALM), photo-bleaching, photo-toxicity, quantum dots, single-molecule switching microscopy (SMSM), spatial resolution, stimulated emission depletion microscopy (STEC), stochastic optical reconstruction microscopy (STORM), temporal resolution, total internal reflection fluorescence (TIRF), viral dynamics

Relation: 10779/rmit.27420903.v1

الاتاحة: https://figshare.com/articles/chapter/Progress_in_Viral_Imaging_by_Super-Resolution_Fluorescence_Microscopy/27420903

المؤلفون: Rana L. Singleton, Carrie A. Sanders, Kevin Jones, Bobby Thorington, Timothy Egbo, Mamie T. Coats, Alain Bopda Waffo

المصدر: Methods and Protocols; Volume 1; Issue 2; Pages: 18

مصطلحات موضوعية: Qβ, read-through protein A 1, foot-and-mouth disease virus (FMDV), membrane proximal external region (MPER), human immunodeficiency virus (HIV), in vitro evolution, proofreading

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/mps1020018

الاتاحة: https://doi.org/10.3390/mps1020018

المؤلفون: Lara Ajamian, Luca Melnychuk, Patrick Jean-Pierre, Gerasimos Zaharatos

المصدر: Viruses; Volume 10; Issue 3; Pages: 100

مصطلحات موضوعية: HIV-1, gp41, membrane proximal external region, MPER, flagellin, adjuvant, DNA vaccine

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Animal Viruses; https://dx.doi.org/10.3390/v10030100

الاتاحة: https://doi.org/10.3390/v10030100

المؤلفون: Luis M. Molinos-Albert, Bonaventura Clotet, Julià Blanco, Jorge Carrillo

المصدر: Frontiers in Immunology, Vol 8 (2017)

مصطلحات موضوعية: human immunodeficiency virus type-1, broadly neutralizing antibodies, membrane proximal external region, B-cells, polyreactivity, membrane interaction, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2017.01154/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/9f69ef82b3c84eff9e51caa961a373b5

المؤلفون: Corti, D, Langedijk, JPM, Hinz, A, Seaman, MS, Vanzetta, F, Fernandez-Rodriguez, BM, Silacci, C, Pinna, D, Jarrossay, D, Balla-Jhagjhoorsingh, S, Willems, B, Zekveld, MJ, Dreja, H, O'Sullivan, E, Pade, C, Orkin, C, Jeffs, SA, Montefiori, DC, Davis, D, Weissenhorn, W, McKnight, A, Heeney, JL, Sallusto, F, Sattentau, QJ, Weiss, RA, Lanzavecchia, A

مصطلحات موضوعية: HUMAN-IMMUNODEFICIENCY-VIRUS, PROXIMAL EXTERNAL REGION, TYPE-1 INFECTION, SUBTYPE-B, ENVELOPE GLYCOPROTEIN, HIV-1 NEUTRALIZATION, PASSIVE TRANSFER, BINDING-SITE, ENV CLONES, IN-VITRO

وصف الملف: ? - ?

Relation: PLOS ONE; e8805; http://qmro.qmul.ac.uk/xmlui/handle/123456789/34429

الاتاحة: http://qmro.qmul.ac.uk/xmlui/handle/123456789/34429
https://doi.org/10.1371/journal.pone.0008805

المؤلفون: Serrano, Soraya, Araujo, Aitziber, Apellaniz, Beatriz, Bryson, Steve, Carravilla, Pablo, de la Arada, Igor, Huarte, Nerea, Rujas, Edurne, Pai, Emil F., Arrondo, Jose L. R., Domene, Carmen, Angeles Jimenez, Maria, Nieva, Jose L.

المصدر: Serrano , S , Araujo , A , Apellaniz , B , Bryson , S , Carravilla , P , de la Arada , I , Huarte , N , Rujas , E , Pai , E F , Arrondo , J L R , Domene , C , Angeles Jimenez , M & Nieva , J L 2014 , ' Structure and Immunogenicity of a Peptide Vaccine, Including the Complete HIV-1 gp41 2F5 Epitope : IMPLICATIONS FOR ANTIBODY RECOGNITION MECHANISM AND IMMUNOGEN DESIGN ' , Journal of Biological Chemistry , vol. 289 , no. 10 , pp. 6565-6580 ....

مصطلحات موضوعية: Fourier Transform IR (FTIR), HIV-1, Liposomes, Nuclear Magnetic Resonance, Peptide Conformation, Vaccine Development, IMMUNODEFICIENCY-VIRUS TYPE-1, PROXIMAL EXTERNAL REGION, HUMAN MONOCLONAL-ANTIBODY, BROADLY NEUTRALIZING ANTIBODIES, ENVELOPE GLYCOPROTEIN, MOLECULAR-DYNAMICS, MEDIATED FUSION, NMR STRUCTURE, FORCE-FIELD, MEMBRANE

وصف الملف: application/pdf

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/structure-and-immunogenicity-of-a-peptide-vaccine-including-the-complete-hiv1-gp41-2f5-epitope(5e798670-ff20-4823-921c-96823313940c).html
https://doi.org/10.1074/jbc.M113.527747
https://kclpure.kcl.ac.uk/ws/files/52931544/J._Biol._Chem._2014_Serrano_6565_80.pdf

المؤلفون: Reardon, Patrick Neal

Thesis Advisors: Spicer, Leonard D

مصطلحات موضوعية: Biophysics, Virology, Biochemistry, gp41, HIV-1, In-Cell NMR, Membrane Proximal External Region

الاتاحة: http://hdl.handle.net/10161/4966

المؤلفون: Huarte Arrayago, Nerea, Araujo Pasarín, Aitziber, Arranz, Rocio, Lorizate Nogales, Maier, Quendler, Heribert, Kunert, Renate, Valpuesta, José M., Nieva Escandón, José Luis

مصطلحات موضوعية: immunodeficiency-virus type-1, proximal external region, large unilamellar vesicles, human monoclonal-antibody, complementarity-determining region, vaccine design, envelope glycoprotein, GP41 ectodomain, conformational constraints, anti-HIV-1 antibodies, AGRICULTURAL AND BIOLOGICAL SCIENCES, MEDICINE, BIOCHEMISTRY AND MOLECULAR BIOLOGY

وصف الملف: application/pdf

Relation: info:eu-repo/grantAgreement/MINECO/BIO2011-29792; info:eu-repo/grantAgreement/MICINN/BFU2010-15703-BMC; http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052740; PLoS ONE 7(12) : (2012) // e52740.; http://hdl.handle.net/10810/9465

الاتاحة: http://hdl.handle.net/10810/9465
https://doi.org/10.1371/journal.pone.0052740

المؤلفون: Franquelim, Henri G., Chiantia, Salvatore, Veiga, Ana Salomé, Santos, Nuno C., Schwille, Petra, Castanho, Miguel A. R. B.

مصطلحات موضوعية: 2F5, 4E10, gp41, HIV-1, Membrane proximal external region, Microscopy

Relation: AIDS 2011, 25:419–428; http://dx.doi.org/10.1097/QAD.0b013e328342ff11; http://hdl.handle.net/10451/6748

الاتاحة: https://doi.org/10.1097/QAD.0b013e328342ff11
http://hdl.handle.net/10451/6748

المؤلفون: Si Min Zhang, Yanning Lu, Ying Liao, Anders Vahlne, Tuan Ling Neo, Ding Xiang Liu, James P. Tam

المساهمون: School of Biological Sciences

المصدر: The International Journal of Biochemistry & Cell Biology

مصطلحات موضوعية: 0301 basic medicine, Gene Expression, Peptide, medicine.disease_cause, Biochemistry, Protein Structure, Secondary, HIV-1, Human immunodeficiency virus type I, Sf9 Cells, self-binding peptides, Coronavirus, SPINE (molecular biology), 6-HB, Six-helix bundle, Coiled coil, chemistry.chemical_classification, ThT, Thioflavin T, Chemistry, Biological sciences [Science], CD, Circular dichroism, Hemagglutinins, Severe acute respiratory syndrome-related coronavirus, Spike Glycoprotein, Coronavirus, Class I viral fusion glycoprotein, MPER, Membrane proximal external region, Protein Binding, viral detection, Zipper, Recombinant Fusion Proteins, PAGE, Polyacrylamide gel electrophoresis, RBD, Receptor binding domain, Amyloidogenic Proteins, HR, Heptad repeat, Spodoptera, IFP, Internal fusion peptide, Article, 03 medical and health sciences, Peptide Library, S, Spike protein, SARS-CoV Spike Protein, Consensus sequence, medicine, Animals, Humans, Avidity, Amino Acid Sequence, Steric β-zipper, Solid-Phase Synthesis Techniques, SARS-CoV, Severe acute respiratory syndrome associated coronavirus, 030102 biochemistry & molecular biology, Cell Biology, SARS-CoV spike protein, Heptad repeat, HEK293 Cells, FP, Fusion peptide, 030104 developmental biology, Peptides, HA, Hemagglutinin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf48e218e01961ac484e4d28f47b8aa
https://doi.org/10.1016/j.biocel.2018.05.012

المؤلفون: Apellaniz Unzalu, Beatriz, García Sáez, Ana J., Huarte Arrayago, Nerea, Kunert, Renate, Vorauer-Uhl, Karola, Katinger, Hermann, Schwille, Petra, Nieva Escandón, José Luis

مصطلحات موضوعية: cholesterol, 19-dioctadecyl-3,3,39,39-tetramethylindodicarbocyanine perchlorate, 1'-dioctadecyl-3,3'-oxacarbocyanine perchlorate, dioleoyl-phosphatidylcholine, giant unilamellar vesicle, multilamellar vesicle, membrane-proximal external region, 1-palmitoyl-2-oleoylphosphatidylcholine, supported-lipid bilayers, sphingomyelin

وصف الملف: application/pdf

Relation: info:eu-repo/grantAgreement/MICINN/BIO2008-00772; https://doi.org/10.1016/j.febslet.2010.03.021; Febs Letters 584(8) : 1591-1596 (2010); http://hdl.handle.net/10810/68862

الاتاحة: http://hdl.handle.net/10810/68862
https://doi.org/10.1016/j.febslet.2010.03.021

المؤلفون: Corti, D, Langedijk, JPM, Hinz, A, Seaman, MS, Vanzetta, F, Fernandez-Rodriguez, BM, Silacci, C, Pinna, D, Jarrossay, D, Balla-Jhagjhoorsingh, S, Willems, B, Zekveld, MJ, Dreja, H, O'Sullivan, E, Pade, C, Orkin, C, Jeffs, SA, Montefiori, DC, Davis, D, Weissenhorn, W, McKnight, A, Heeney, JL, Sallusto, F, Sattentau, QJ, Weiss, RA, Lanzavecchia, A

المصدر: PLOS ONE , 5 (1) , Article e8805. (2010)

مصطلحات موضوعية: HUMAN-IMMUNODEFICIENCY-VIRUS, PROXIMAL EXTERNAL REGION, TYPE-1 INFECTION, SUBTYPE-B, ENVELOPE GLYCOPROTEIN, HIV-1 NEUTRALIZATION, PASSIVE TRANSFER, BINDING-SITE, ENV CLONES, IN-VITRO

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/141355/1/141355.pdf; https://discovery.ucl.ac.uk/id/eprint/141355/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/141355/1/141355.pdf
https://discovery.ucl.ac.uk/id/eprint/141355/

المؤلفون: Hinz, A, Hulsik, DL, Forsman, A, Koh, WWL, Belrhali, H, Gorlani, A, de Haard, H, Weiss, RA, Verrips, T, Weissenhorn, W

المصدر: PLOS ONE , 5 (5) , Article e10482. (2010)

مصطلحات موضوعية: IMMUNODEFICIENCY-VIRUS TYPE-1, HUMAN MONOCLONAL-ANTIBODY, CD4 BINDING-SITE, PROXIMAL EXTERNAL REGION, FUSION INHIBITOR T-20, ENVELOPE GLYCOPROTEIN, SACCHAROMYCES-CEREVISIAE, MEMBRANE-FUSION, HEAVY-CHAIN, GP41

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/92971/1/92971.pdf; https://discovery.ucl.ac.uk/id/eprint/92971/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/92971/1/92971.pdf
https://discovery.ucl.ac.uk/id/eprint/92971/

المؤلفون: Julian Buchrieser, Marie-Christine Vaney, Marija Backovic, Eduard Baquero, Bruno Baron, Katinka Ruigrok, Patrick England, Jan Hellert, Félix A. Rey, Olivier Schwartz

المساهمون: Virologie Structurale - Structural Virology, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5), Virus et Immunité - Virus and immunity, Vaccine Research Institute (VRI), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), This work was funded by the European Research council (ERC ‘CelCelFus’ grant #340371) awarded to F.A.R, and recurrent funding from the Institut Pasteur (IP) and CNRS, We thank Ahmed Haouz and staff at the IP core facility for protein crystallization, and staff at the Proxima-2 beamline at the SOLEIL synchrotron for assistance with data collection and processing. We also thank Ignacio Fernandez for helpful discussions and critical reading of the manuscript, Delphine Brun for technical assistance, and Etienne Simon-Loriere for discussions and help with phylogenetic analyses., Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Virus et Immunité - Virus and immunity (CNRS-UMR3569), Vaccine Research Institute [Créteil, France] (VRI), Virologie Structurale, Virus et Immunité

المصدر: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2019, pp.S0022-2836(19)30616-3. ⟨10.1016/j.jmb.2019.10.020⟩
Journal of Molecular Biology, 2019, pp.S0022-2836(19)30616-3. ⟨10.1016/j.jmb.2019.10.020⟩

مصطلحات موضوعية: TM, transmembrane subunit, WT, wild type, Models, Molecular, Protein Conformation, HR, heptad repeat, Pregnancy Proteins, Crystallography, X-Ray, 0302 clinical medicine, Viral Envelope Proteins, MPER, membrane-proximal external region, Aa, amino acid, PDB, protein data bank, TMA, transmembrane anchor, GFP, green fluorescent protein, chemistry.chemical_classification, Helix bundle, 0303 health sciences, Syncytin, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Transmembrane protein, 3. Good health, Cell biology, HIV, human immunodeficiency virus, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], Env, envelope protein, TME, ectodomain of the transmembrane subunit, Syn1, human syncytin-1, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, HTLV, human T-lymphotropic virus, EBOV, Ebola virus, Structural biology, Fusion protein, SU, surface subunit, BLV, bovine leukemia virus, MPMV, Mason–Pfizer monkey virus, MARV, Marburg virus, Protein subunit, Membrane fusion, SEM, standard error of the mean value, Article, Syn2, human syncytin-2, TEV, tobacco etch virus, ER, endoplasmic reticulum, 03 medical and health sciences, Humans, HERV, human endogenous retrovirus, Protein Interaction Domains and Motifs, Amino Acid Sequence, Molecular Biology, 030304 developmental biology, X-ray crystallography, Lipid bilayer fusion, Gene Products, env, Membrane protein, chemistry, SP, signal peptide, SEC, size exclusion chromatography, Gammaretrovirus, Glycoprotein, 030217 neurology & neurosurgery, 6HB, six-helix bundle

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813f60ae76087870391779aea60f82cd
https://hal.archives-ouvertes.fr/hal-02375766