يعرض 1 - 20 نتائج من 27,785 نتيجة بحث عن '"Protein-Tyrosine-Phosphatase"', وقت الاستعلام: 0.58s تنقيح النتائج
  1. 1
    Academic Journal
    Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors.

    المؤلفون: Sait, Sameer Farouk1,2, Kwan Ho Tang3,4, Angus, Steven P.5, Brown, Rebecca6, Daochun Sun1,7,8, Xuanhua Xie1, Iltis, Charlene1, Lien, Michelle9, Socci, Nicholas D.10, Bale, A.9,11, Davis, Christopher5, Dixon, Shelley A. H.5, Chi Zhang5, Clapp, D. Wade5, Neel, Benjamin G.3 Benjamin.neel@nyulangone.org, Parada, Luis F.1,10,12,13 paradal@mskcc.org

    المصدر: Proceedings of the National Academy of Sciences of the United States of America. 1/7/2025, Vol. 122 Issue 1, p1-12. 26p.

    مصطلحات موضوعية: *SCHWANNOMAS, *PROTEIN-tyrosine phosphatase, *PROTEIN kinases, *NEUROFIBROMATOSIS 1, *HYDROXYCHLOROQUINE


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  2. 2
    Academic Journal
    Identification of natural curcumins as potential dual inhibitors of PTP1B and α-glucosidase through experimental and computational study.

    المؤلفون: Anh-Tuan Nguyen1, Minh Quan Pham2, Phi-Hung Nguyen2,3 nguyenphihung@ich.vast.vn, Dao Cuong To4, Ngoc Quang Dang1, The-Hung Nguyen5, Huu-Tho Nguyen5, Tien-Dung Nguyen5,6, Khanh-Huyen Thi Pham7, Manh-Hung Tran7

    المصدر: Kuwait Journal of Science. Jan2025, Vol. 52 Issue 1, p1-8. 8p.

    مصطلحات موضوعية: *CURCUMIN, *PROTEIN-tyrosine phosphatase, *TURMERIC, *PHOSPHOPROTEIN phosphatases, *DENSITY functional theory

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  3. 3
    Academic Journal
    PTPRJ is a negative regulator of insulin signaling in neuronal cells, impacting protein biosynthesis, and neurite outgrowth.

    المؤلفون: Ulke, Jannis1,2 (AUTHOR), Chopra, Simran3 (AUTHOR), Kadiri, Otsuware Linda‐Josephine3 (AUTHOR), Geserick, Peter1,2 (AUTHOR), Stein, Vanessa1,2 (AUTHOR), Cheshmeh, Sahar3 (AUTHOR), Kleinridders, André3 (AUTHOR), Kappert, Kai1,2 (AUTHOR) kai.kappert@charite.de

    المصدر: Journal of Neuroendocrinology. Dec2024, Vol. 36 Issue 12, p1-16. 16p.

    مصطلحات موضوعية: *PROTEIN-tyrosine phosphatase, *PHOSPHOPROTEIN phosphatases, *INSULIN receptors, *PROTEIN synthesis, *INSULIN resistance, *KINASES, *MITOGEN-activated protein kinase phosphatases


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  4. 4
    Academic Journal
    Does Metabolic Manager Show Encouraging Outcomes in Alzheimer's?: Challenges and Opportunity for Protein Tyrosine Phosphatase 1b Inhibitors.

    المؤلفون: Singh, Ritu1 (AUTHOR), Jain, Smita1 (AUTHOR), Paliwal, Vartika1 (AUTHOR), Verma, Kanika2 (AUTHOR), Paliwal, Sarvesh1 (AUTHOR) psarvesh@banasthali.ac.in, Sharma, Swapnil1 (AUTHOR) skspharmacology@gmail.com

    المصدر: Drug Development Research. Dec2024, Vol. 85 Issue 8, p1-25. 25p.

    مصطلحات موضوعية: *PROTEIN-tyrosine phosphatase, *PHOSPHOPROTEIN phosphatases, *HEAT shock proteins, *ALZHEIMER'S disease, *METABOLIC disorders


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  5. 5
    Academic Journal
    Exploring the Antimycobacterial Potential of Podocarpusflavone A from Kielmeyera membranacea : In Vitro and In Vivo Insights.

    المؤلفون: Araujo, Marlon Heggdorne de1,2 (AUTHOR) marlon.heggdorne@gmail.com, Muñoz Sánchez, Salomé2 (AUTHOR) h.p.spaink@biology.leidenuniv.nl, Simão, Thatiana Lopes Biá Ventura3 (AUTHOR) thativentura@yahoo.com.br, Nowik, Natalia2 (AUTHOR), Antunes, Stella Schuenck1,4 (AUTHOR) nelilmaromeiro@gmail.com, Pinto, Shaft Corrêa1 (AUTHOR) shaftcp@yahoo.com.br, Sorze, Davide5 (AUTHOR) davide.sorze@studenti.unipd.it, Boldrin, Francesca5 (AUTHOR) francesca.boldrin@unipd.it, Manganelli, Riccardo5 (AUTHOR) riccardo.manganelli@unipd.it, Correia Romeiro, Nelilma4 (AUTHOR), Lasunskaia, Elena B.3 (AUTHOR) elena@uenf.br, Verbeek, Fons J.6 (AUTHOR) f.j.verbeek@liacs.leidenuniv.nl, Spaink, Herman P.2 (AUTHOR), Muzitano, Michelle Frazão1 (AUTHOR) mfmuzitano@macae.ufrj.br

    المصدر: Pharmaceuticals (14248247). Dec2024, Vol. 17 Issue 12, p1560. 20p.

    مصطلحات موضوعية: *MYCOBACTERIUM tuberculosis, *PROTEIN-tyrosine phosphatase, *PHOSPHOPROTEIN phosphatases, *DIRECT action, *TUBERCULOSIS

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  6. 6
    Academic Journal
    Regulation of STAT5 phosphorylation and interaction with SHP1 by lnc-AC004893, a long non-coding RNA overexpressed in myeloproliferative neoplasms.

    المؤلفون: Yang, Junjun1 (AUTHOR), Ruan, Jichen2 (AUTHOR), Zhou, Bin3 (AUTHOR), Ye, Sisi3 (AUTHOR), Gao, Shenmeng3 (AUTHOR) gaoshenmeng77@wzhospital.cn, Zheng, Xiaoqun1,4 (AUTHOR) jszhengxq@163.com

    المصدر: Hematology. Dec2024, Vol. 29 Issue 1, p1-10. 10p.

    مصطلحات موضوعية: *LINCRNA, *PROTEIN-tyrosine phosphatase, *MYELOPROLIFERATIVE neoplasms, *PHOSPHOPROTEIN phosphatases, *STAT proteins


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  7. 7
    Academic Journal
    Overexpression of PTPN21 promotes proliferation of EGF-stimulated acute lymphoblastic leukemia cells via the MAPK signaling pathways.

    المؤلفون: Zhu, Ni1 (AUTHOR), Wei, Jieping2 (AUTHOR), Wang, Li-Mengmeng2,3,4 (AUTHOR), Huang, He2,3,4 (AUTHOR), Xiao, Haowen5 (AUTHOR) haowenxiaoxiao@zju.edu.cn

    المصدر: Hematology. Dec2024, Vol. 29 Issue 1, p1-12. 12p.

    مصطلحات موضوعية: *PROTEIN-tyrosine phosphatase, *LYMPHOBLASTIC leukemia, *PROTEIN-tyrosine kinases, *PHOSPHOPROTEIN phosphatases, *CELL cycle


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  8. 8
    Academic Journal
    In Silico Molecular Dynamics and 3D‐QSAR Study on Thiazolidinedione Derivatives as Dual Inhibitors of DPP IV and PTP1B (DDPI's) for the Management of T2DM.

    المؤلفون: Singh, Yogesh1 (AUTHOR), Thareja, Suresh1 (AUTHOR) sureshthareja@gmail.com

    المصدر: ChemistrySelect. Dec2024, Vol. 9 Issue 45, p1-26. 26p.

    مصطلحات موضوعية: *PROTEIN-tyrosine phosphatase, *MOLECULAR docking, *PHOSPHOPROTEIN phosphatases, *MOLECULAR dynamics, *CONTOURS (Cartography)


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  9. 9
    Academic Journal
    The Toxoplasma secreted effector TgWIP modulates dendritic cell motility by activating host tyrosine phosphatases Shp1 and Shp2

    المؤلفون: Morales, Pavel, Brown, Abbigale J, Sangaré, Lamba Omar, Yang, Sheng, Kuihon, Simon VNP, Chen, Baoyu, Saeij, Jeroen PJ

    المصدر: Cellular and Molecular Life Sciences. 81(1)

    مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Infectious Diseases, Biodefense, Foodborne Illness, Emerging Infectious Diseases, 2.1 Biological and endogenous factors, Toxoplasma, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Dendritic Cells, Cell Movement, Animals, Protein Tyrosine Phosphatase, Non-Receptor Type 6, Protozoan Proteins, Humans, Mice, rho-Associated Kinases, Toxoplasmosis, Mice, Inbred C57BL, TgWIP, Dendritic cells, Shp1, Shp2, Dissemination, Physiology, Clinical Sciences, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medical biochemistry and metabolomics, Oncology and carcinogenesis

    وصف الملف: application/pdf

    URL الوصول: https://escholarship.org/uc/item/3tw9x3bc
    https://escholarship.org/content/qt3tw9x3bc/qt3tw9x3bc.pdf

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  10. 10
    Academic Journal
    Emerging Functions of Protein Tyrosine Phosphatases in Plants.

    المؤلفون: Xin, Jing1 (AUTHOR) xinjing_0223@163.com, Li, Chuanling2 (AUTHOR) chuanlingzz@163.com, Liu, Xiaoqian1 (AUTHOR) xiaoqianliu95@163.com, Shi, Xueke1 (AUTHOR) 15175130775@163.com, Sun, Yu1 (AUTHOR) yusun05@mail.hebtu.edu.cn, Shang, Jian-Xiu1 (AUTHOR) shangjianxiu@mail.hebtu.edu.cn

    المصدر: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12050. 22p.

    مصطلحات موضوعية: *PHOSPHOPROTEIN phosphatases, *PROTEIN-tyrosine phosphatase, *PLANT proteins, *PROTEIN kinases, *PLANT physiology

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  11. 11
    Academic Journal
    PTP1B Modulates Carotid Plaque Vulnerability in Atherosclerosis Through Rab5‐PDGFRβ‐Mediated Endocytosis Disruption and Apoptosis.

    المؤلفون: Zhang, Xiao1,2 (AUTHOR), Xu, Ran1,2 (AUTHOR), Wang, Tao1,2 (AUTHOR), Li, Jiayao1,2 (AUTHOR), Sun, Yixin3,4 (AUTHOR), Cui, Shengyan1,2 (AUTHOR), Xing, Zixuan5 (AUTHOR), Lyu, Xintao6 (AUTHOR), Yang, Ge7,8 (AUTHOR), Jiao, Liqun1,2,9 (AUTHOR) liqunjiao@sina.cn, Li, Wenjing7,8 (AUTHOR) wenjing.li@ia.ac.cn

    المصدر: CNS Neuroscience & Therapeutics. Nov2024, Vol. 30 Issue 11, p1-14. 14p.

    مصطلحات موضوعية: *ATHEROSCLEROTIC plaque, *PROTEIN-tyrosine phosphatase, *VASCULAR smooth muscle, *PHOSPHOPROTEIN phosphatases, *MUSCLE cells

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  12. 12
    Academic Journal
    A New Benzofuran from the Roots of Eupatorium chinense L. and Its a-Glucosidase and PTP1B Inhibitory Activities.

    المؤلفون: Qiangsu Qin1, Huishu Yang1, Yifa Qin1, Yifan Bai1, Renqin Tang1, Ting Yan1, Zhaoxia Liu1, Chengxiong Liu1 liuchengxiong666@126.com, Xiaoqin Yu1 262480010@qq.com

    المصدر: Records of Natural Products. Nov/Dec2024, Vol. 18 Issue 6, p693-698. 6p.

    مصطلحات موضوعية: *PROTEIN-tyrosine phosphatase, *PHOSPHOPROTEIN phosphatases, *EUPATORIUM, *MOLECULAR docking, *BENZOFURAN

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  13. 13
    Academic Journal
    Meis1 Targets Protein Tyrosine Phosphatase Receptor J in Fibroblast to Retard Chronic Kidney Disease Progression.

    المؤلفون: Bai, Mi1,2,3 (AUTHOR), Xu, Shuang1,2 (AUTHOR), Jiang, Mingzhu1,2 (AUTHOR), Guo, Yuxian1,2 (AUTHOR), Hu, Dandan1,2 (AUTHOR), He, Jia1,2 (AUTHOR), Wang, Ting1,2 (AUTHOR), Zhang, Yu1,2,4 (AUTHOR), Guo, Yan1,2 (AUTHOR), Zhang, Yue1,2,3 (AUTHOR), Huang, Songming1,2,3 (AUTHOR), Jia, Zhanjun1,2,3 (AUTHOR) jiazhanjun72@njmu.edu.cn, Zhang, Aihua1,2,3 (AUTHOR) zhaihua@njmu.edu.cn

    المصدر: Advanced Science. 10/23/2024, Vol. 11 Issue 39, p1-18. 18p.

    مصطلحات موضوعية: *RENAL fibrosis, *PROTEIN-tyrosine phosphatase, *CHRONIC kidney failure, *PHOSPHOPROTEIN phosphatases, *KIDNEY diseases

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  14. 14
    Academic Journal
    Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition.

    المؤلفون: Paramasivam, Prabu1 (AUTHOR), Choi, Seong Won1 (AUTHOR), Poddar, Ranjana1 (AUTHOR), Paul, Surojit1 (AUTHOR) spaul@salud.unm.edu

    المصدر: Journal of Neuroinflammation. 10/22/2024, Vol. 21 Issue 1, p1-20. 20p.

    مصطلحات موضوعية: *PROTEIN-tyrosine phosphatase, *STROKE patients, *BRAIN injuries, *INFLAMMATION, *BRAIN damage, *KINASES

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  15. 15
    Academic Journal
    Proteomics analysis reveals the differential protein expression of female and male adult Toxocara canis using Orbitrap Astral analyzer.

    المؤلفون: Qiu, Hui-Jie1 (AUTHOR), Zhou, Ya-Jia1 (AUTHOR), Li, Zhi-Yu1 (AUTHOR), Lv, Yi-Han1 (AUTHOR), Zhu, Xing-Quan1 (AUTHOR) xingquanzhu1@hotmail.com, Zheng, Wen-Bin1 (AUTHOR) wenbinzheng1@126.com

    المصدر: Infectious Diseases of Poverty. 10/9/2024, p1-13. 13p.

    مصطلحات موضوعية: *TRANSCRIPTION factors, *PROTEIN-tyrosine phosphatase, *PHOSPHOPROTEIN phosphatases, *PROTEIN expression, *CANIS

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  16. 16
    Academic Journal
    Design and Synthesis of Pyridyl and 2-Hydroxyphenyl Chalcones with Antitubercular Activity.

    المؤلفون: Aziafor, Kelphina1 (AUTHOR) p2621865@alumni365.dmu.ac.uk, Ruparelia, Ketan1 (AUTHOR) kruparel@dmu.ac.uk, Moulds, Brandon1 (AUTHOR) brandon.moulds@dmu.ac.uk, Zloh, Mire2,3 (AUTHOR) mire.zloh@faculty-pharmacy.com, Parish, Tanya4 (AUTHOR) tanya.parish@seattlechildrens.org, Brucoli, Federico1 (AUTHOR) federico.brucoli@dmu.ac.uk

    المصدر: Molecules. Oct2024, Vol. 29 Issue 19, p4539. 17p.

    مصطلحات موضوعية: *PROTEIN-tyrosine phosphatase, *CLAISEN condensation, *PHOSPHOPROTEIN phosphatases, *MYCOBACTERIUM tuberculosis, *CHALCONES, *CHALCONE

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  17. 17
    Academic Journal
    Pleiotrophin Activates cMet- and mTORC1-Dependent Protein Synthesis through PTPRZ1—The Role of α ν β 3 Integrin.

    المؤلفون: Mourkogianni, Eleni1 (AUTHOR) eleni9119@yahoo.gr, Karavasili, Katerina1 (AUTHOR), Xanthopoulos, Athanasios1 (AUTHOR), Enake, Michaela-Karina1 (AUTHOR), Menounou, Lydia1 (AUTHOR), Papadimitriou, Evangelia1 (AUTHOR) epapad@upatras.gr

    المصدر: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10839. 16p.

    مصطلحات موضوعية: *CELL migration, *PROTEIN-tyrosine phosphatase, *PEPTIDES, *CELL physiology, *ENDOTHELIAL cells

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  18. 18
    Academic Journal
    Preliminary Investigation of Potential Early Biomarkers for Gestational Diabetes Mellitus: Insights from PTRPG and IGKV2D-28 Expression Analysis.

    المؤلفون: Payot, Mariejim Diane1,2 (AUTHOR) aevillavieja@ust.edu.ph, Villavieja, Adrian2 (AUTHOR), Pineda-Cortel, Maria Ruth1,2,3 (AUTHOR)

    المصدر: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10527. 11p.

    مصطلحات موضوعية: *GENE expression, *PROTEIN-tyrosine phosphatase, *RECEIVER operating characteristic curves, *GLUCOSE tolerance tests, *PHOSPHOPROTEIN phosphatases

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  19. 19
    Academic Journal
    VEPTP inhibition with an extracellular domain targeting antibody did not restore albuminuria in a mouse model of diabetic kidney disease.

    المؤلفون: Rana, Rajashree1,2 (AUTHOR) rrana5@its.jnj.com, Natoli, Thomas A.1,2 (AUTHOR), Khandelwal, Puneet3 (AUTHOR), Pissios, Pavlos1,2 (AUTHOR), Muhammad, Abdul Bari1,2 (AUTHOR), Chipashvili, Vaja1,2 (AUTHOR), Farrington, Krista P.1,2 (AUTHOR), Zhou, Wen1,2 (AUTHOR), Zheng, Gang1,2 (AUTHOR), Bukanov, Nikolay O.1,2 (AUTHOR), Pocai, Alessandro1,2 (AUTHOR), Magnone, Maria Chiara1,2 (AUTHOR) magnonem2004@yahoo.it

    المصدر: Physiological Reports. Sep2024, Vol. 12 Issue 18, p1-15. 15p.

    مصطلحات موضوعية: *DIABETIC nephropathies, *PROTEIN-tyrosine phosphatase, *PHOSPHOPROTEIN phosphatases, *CELL permeability, *KIDNEY physiology

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  20. 20
    Academic Journal
    Protein tyrosine phosphatase receptor type O serves as a key regulator of insulin resistance-induced α-synuclein aggregation in Parkinson's disease.

    المؤلفون: Tan, Shichuan1,2,3 (AUTHOR), Chi, Huizhong1,2 (AUTHOR), Wang, Pin4 (AUTHOR), Zhao, Rongrong1,2 (AUTHOR), Zhang, Qinran1,5 (AUTHOR), Gao, Zijie1,2 (AUTHOR), Xue, Hao1,2 (AUTHOR), Tang, Qilin1,2 (AUTHOR) Qilin.Tang@sdu.edu.cn, Li, Gang1,2 (AUTHOR) dr.ligang@sdu.edu.cn

    المصدر: Cellular & Molecular Life Sciences. 9/14/2024, Vol. 81 Issue 1, p1-17. 17p.

    مصطلحات موضوعية: *PROTEIN-tyrosine phosphatase, *PARKINSON'S disease, *DOPAMINERGIC neurons, *PHOSPHOPROTEIN phosphatases, *GENE regulatory networks

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