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المؤلفون: Christopher Mapperley, Christophorou Ma, Kamil R. Kranc, Russell, Hannah Lawson, Young C
مصطلحات موضوعية: musculoskeletal diseases, Haematopoiesis, medicine.anatomical_structure, Regeneration (biology), medicine, Protein-Arginine Deiminase Type-4, Bone marrow, Stem cell, Biology, Embryonic stem cell, Cell biology, TAL1, Adult stem cell
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المؤلفون: Jing Ye, Chunyu Tan, Martin Herrmann, Nanfang Pan, Wenpeng Song
المصدر: Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunologyمصطلحات موضوعية: rheumatoid arthritis, lcsh:Immunologic diseases. Allergy, 0301 basic medicine, chronic inflammation, Neutrophils, Immunology, neutrophil extracellular traps, Autoimmunity, Review, medicine.disease_cause, Extracellular Traps, Pathogenesis, Arthritis, Rheumatoid, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Immunology and Allergy, Animals, Humans, ddc:610, anti-citrullinated protein antibodies, Autoantibodies, biology, business.industry, Anti–citrullinated protein antibody, Experimental Animal Models, Neutrophil extracellular traps, medicine.disease, Disease Models, Animal, 030104 developmental biology, Rheumatoid arthritis, Antirheumatic Agents, citrullinated autoantigens, biology.protein, Protein-Arginine Deiminase Type-4, protein-arginine deiminase type 4, lcsh:RC581-607, business, Biomarkers, 030215 immunology, Signal Transduction
وصف الملف: application/pdf; image/tiff
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المؤلفون: Ying Xing, Dandan Li, Yang Qu, Meiyan Liu, Chunhong Li, Xue Teng, Li Cai
المصدر: Molecular Medicine Reports
مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, Cancer Research, Epithelial-Mesenchymal Transition, Lung Neoplasms, Gene Expression, Biology, migration, Biochemistry, Metastasis, 03 medical and health sciences, Mothers against decapentaplegic homolog 3, 0302 clinical medicine, Protein-Arginine Deiminase Type 4, Cell Movement, Cell Line, Tumor, protein-arginine deiminase type-4, Genetics, medicine, Biomarkers, Tumor, Humans, Epithelial–mesenchymal transition, Epigenetics, RNA, Small Interfering, Lung cancer, Molecular Biology, A549 cell, Oncogene, Cancer, Articles, respiratory system, medicine.disease, invasion, Immunohistochemistry, respiratory tract diseases, lung cancer, 030104 developmental biology, Oncology, A549 Cells, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Cancer research, Protein-Arginine Deiminases, Molecular Medicine, RNA Interference, Signal Transduction
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المؤلفون: Peiqing Zhao, Tao Li, Qiaoli Zhai, Lianqing Wang
المصدر: Acta Biochimica et Biophysica Sinica. 49:567-572
مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, Cellular differentiation, Biophysics, DNMT3A Gene, Apoptosis, Biochemistry, Arthritis, Rheumatoid, 03 medical and health sciences, 0302 clinical medicine, Protein-Arginine Deiminase Type 4, Neoplasms, Histone methylation, Transcriptional regulation, Humans, Regulation of gene expression, biology, Citrullination, Acetylation, Cell Differentiation, General Medicine, Cell biology, 030104 developmental biology, Histone, Gene Expression Regulation, 030220 oncology & carcinogenesis, Biocatalysis, Protein-Arginine Deiminases, biology.protein, Protein-Arginine Deiminase Type-4, Tumor Suppressor Protein p53, Nucleophosmin
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المصدر: Annals of the Rheumatic Diseases. 78:434-436
مصطلحات موضوعية: 030203 arthritis & rheumatology, 0301 basic medicine, biology, business.industry, Immunology, Autoantibody, Protein-arginine deiminase, Arthritis, medicine.disease, General Biochemistry, Genetics and Molecular Biology, Serology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Rheumatology, Rheumatoid arthritis, biology.protein, Immunology and Allergy, Medicine, Rheumatoid factor, Protein-Arginine Deiminase Type-4, Antibody, business
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المؤلفون: Craig N. Morrell, Daphne N. Pariser, Zachary T. Hilt, Preeti Maurya
المصدر: Circ Res
مصطلحات موضوعية: Inflammation, biology, Physiology, business.industry, Thrombosis, Vascular System Injuries, medicine.disease, Article, Von Willebrand factor, Protein-Arginine Deiminase Type 4, hemic and lymphatic diseases, Immunology, von Willebrand Factor, medicine, biology.protein, Protein-Arginine Deiminase Type-4, Humans, medicine.symptom, Cardiology and Cardiovascular Medicine, business
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المؤلفون: Daniella M. Mizurini, Robert J. Seward, Nicoletta Sorvillo, Nathan I. Shapiro, Paul R. Thompson, Ronak Tilvawala, Catherine E. Costello, Caleb Staudinger, Denisa D. Wagner, Eranthie Weerapana, Deya Cherpokova, Carmen H. Coxon, Kimberly Martinod, Ari J. Salinger
المصدر: Circulation research. 125(5)
مصطلحات موضوعية: 0301 basic medicine, Blood Platelets, Male, Physiology, Mice, Transgenic, 030204 cardiovascular system & hematology, 03 medical and health sciences, Mice, Young Adult, 0302 clinical medicine, Von Willebrand factor, Protein-Arginine Deiminase Type 4, hemic and lymphatic diseases, von Willebrand Factor, medicine, Animals, Humans, Platelet, PAD4, Aged, chemistry.chemical_classification, Mice, Knockout, biology, Chemistry, Citrullination, Thrombosis, Neutrophil extracellular traps, Vascular System Injuries, medicine.disease, ADAMTS13, VWF-platelet strings, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, Enzyme, Histone, biology.protein, Protein-Arginine Deiminase Type-4, Female, Cardiology and Cardiovascular Medicine
وصف الملف: Print-Electronic
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المؤلفون: Abu Bakar Salleh, Izzuddin Ahmad Nadzirin, Bimo Ario Tejo, Mohd Basyaruddin Abdul Rahman, Adam Leow Thean Chor
المصدر: Computational Biology and Chemistry. 92:107487
مصطلحات موضوعية: 0301 basic medicine, Peptide, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Protein-Arginine Deiminase Type 4, Structural Biology, Drug Discovery, Peptide synthesis, Humans, Enzyme Inhibitors, IC50, chemistry.chemical_classification, Molecular Structure, Organic Chemistry, Rational design, Citrullination, Molecular Docking Simulation, Computational Mathematics, 030104 developmental biology, chemistry, Docking (molecular), Phosphopyruvate Hydratase, 030220 oncology & carcinogenesis, Protein-Arginine Deiminase Type-4, Peptides, Canavanine
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المؤلفون: Maximilian Mauler, Kimberly Martinod, Denisa D. Wagner, Alexander Savchenko, Luise Erpenbeck, Maureen Gallant, Stephen M. Cifuni, Hideki Hayashi, Deya Cherpokova, Thilo Witsch
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: 0301 basic medicine, Pathology, medicine.medical_specialty, Hydrolases, Cardiac fibrosis, Pulmonary Fibrosis, Immunology, Inflammation, Extracellular Traps, Ventricular Function, Left, Article, Mice, 03 medical and health sciences, Protein-Arginine Deiminase Type 4, Fibrosis, Extracellular, Animals, Immunology and Allergy, Medicine, Platelet, Research Articles, Pressure overload, business.industry, Myocardium, Age Factors, Neutrophil extracellular traps, medicine.disease, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, Protein-Arginine Deiminase Type-4, Collagen, medicine.symptom, Reactive Oxygen Species, business
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المؤلفون: Michael Mahler, Laura Martinez-Prat, Erika Darrah
المصدر: The Journal of rheumatology. 46(3)
مصطلحات موضوعية: business.industry, Hydrolases, Immunology, Autoantibody, Arthritis, Context (language use), medicine.disease, Arthritis, Rheumatoid, Rheumatology, Protein-Arginine Deiminase Type 4, Rheumatoid arthritis, PADI4, Immunology and Allergy, Medicine, Protein-Arginine Deiminase Type-4, Rheumatoid factor, Humans, business, Arginine deiminase, Autoantibodies
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المؤلفون: I-Cheng Ho, Hui-Hsin Chang, Nishant Dwivedi, Anthony P. Nicholas
المصدر: Arthritis & Rheumatology. 67:2323-2334
مصطلحات موضوعية: musculoskeletal diseases, Immunoprecipitation, Immunology, Phosphatase, Citrullination, Neutrophil extracellular traps, Protein tyrosine phosphatase, Biology, Protein citrullination, Molecular biology, eye diseases, PTPN22, Rheumatology, immune system diseases, Immunology and Allergy, Protein-Arginine Deiminase Type-4, skin and connective tissue diseases
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المؤلفون: Lonneke A. van Vught, Theodora A. M. Claushuis, Tom van der Poll, Henk A. van Veen, Jacqueline M. Lankelma, Alex F. de Vos, Cornelis van 't Veer, Nicole N. van der Wel, Lieve E. H. van der Donk, Anna L. Luitse, Louis Boon, Onno J. de Boer, Joris J. T. H. Roelofs
المساهمون: ACS - Pulmonary hypertension & thrombosis, Center of Experimental and Molecular Medicine, Graduate School, AII - Infectious diseases, Experimental Immunology, Cell Biology and Histology, Medical Biology, AGEM - Endocrinology, metabolism and nutrition, APH - Health Behaviors & Chronic Diseases, Pathology, ACS - Diabetes & metabolism, AII - Inflammatory diseases, ACS - Heart failure & arrhythmias, Medical Microbiology and Infection Prevention, 01 Internal and external specialisms, Infectious diseases, ANS - Neuroinfection & -inflammation, APH - Personalized Medicine
المصدر: Journal of immunology (Baltimore, Md., 201(4), 1241-1252. American Association of Immunologists
مصطلحات موضوعية: 0301 basic medicine, Lung, biology, Klebsiella pneumoniae, Chemistry, Immunology, Citrullination, Inflammation, Neutrophil extracellular traps, medicine.disease, biology.organism_classification, Microbiology, respiratory tract diseases, Sepsis, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Histone, medicine.anatomical_structure, 030220 oncology & carcinogenesis, medicine, biology.protein, Immunology and Allergy, Protein-Arginine Deiminase Type-4, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25935cf6fea7afee883093f67ff055c7
https://pure.amc.nl/en/publications/role-of-peptidylarginine-deiminase -4-in-neutrophil-extracellular-trap-formation-and-host-defense-during-klebsiella-pneumoniaeinduced-pneumoniaderived-sepsis(5bb50349-e32a-4edb-b4ea-b502cb8a84cc).html -
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المؤلفون: Christina J. Dreyton, Paul R. Thompson, Bryan Knuckley, Daniel M. Lewallen, Justin E. Jones
المصدر: Biochemistry
مصطلحات موضوعية: Hydrolases, Protein-arginine deiminase, Citrullination, Hydrogen-Ion Concentration, Biology, Biochemistry, Isozyme, Article, Substrate Specificity, Isoenzymes, Kinetics, Histone H3, Protein-Arginine Deiminase Type 4, Protein-Arginine Deiminase Type 1, Transcription (biology), Protein-Arginine Deiminase Type 2, Biocatalysis, Protein-Arginine Deiminases, Solvents, Humans, Protein-Arginine Deiminase Type-4, Calcium, Cysteine
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المؤلفون: Humberto J. Ochoa, Maxwell P. Lee, Lalage M. Wakefield, Nellie Moshkovich, Binwu Tang, Howard H. Yang
المصدر: Cancer Research. 79:3676-3676
مصطلحات موضوعية: musculoskeletal diseases, Cancer Research, Gene knockdown, Cancer, Tumor initiation, Biology, medicine.disease, Breast cancer, Oncology, Cancer stem cell, PADI4, medicine, Cancer research, Protein-Arginine Deiminase Type-4, Stem cell
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المؤلفون: Guang-Yaw Liu, Jyung-Hurng Liu, Chien-Yun Lee, Chu-Cheng Lin, Yi-Liang Liu, Hui-Chih Hung
المصدر: Scientific Reports
مصطلحات موضوعية: Protein Conformation, alpha-Helical, 0301 basic medicine, Stereochemistry, Dimer, Genetic Vectors, Beta sheet, Gene Expression, Plasma protein binding, Molecular Dynamics Simulation, Crystallography, X-Ray, Article, Substrate Specificity, Histones, 03 medical and health sciences, chemistry.chemical_compound, Protein structure, Protein-Arginine Deiminase Type 4, Catalytic Domain, Escherichia coli, Humans, Protein Isoforms, Protein Interaction Domains and Motifs, Cloning, Molecular, Binding site, Multidisciplinary, 030102 biochemistry & molecular biology, biology, Chemistry, Substrate (chemistry), Active site, Recombinant Proteins, Kinetics, 030104 developmental biology, Biochemistry, Mutation, Biocatalysis, Protein-Arginine Deiminases, biology.protein, Protein-Arginine Deiminase Type-4, Protein Conformation, beta-Strand, Protein Multimerization, Hydrophobic and Hydrophilic Interactions, Protein Binding
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المؤلفون: Rafael Herrera-Esparza, Esperanza Avalos-Díaz, J. D. Murillo-Vazquez, Juan-José Bollain y Goytia, Mayra Rodríguez-Rodríguez, Deyanira Pacheco-Tovar, María-Elena Pérez-Pérez, Guadalupe Pacheco-Tovar
المصدر: Journal of Immunology Research
Journal of Immunology Research, Vol 2017 (2017)مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Lipopolysaccharides, Arginine, Article Subject, Ductal cells, Hydrolases, Immunology, Apoptosis, Biology, Autoantigens, Salivary Glands, BALB/c, 03 medical and health sciences, Mice, 0302 clinical medicine, Adenosine Triphosphate, Western blot, Protein-Arginine Deiminase Type 4, Protein-Arginine Deiminase Type 2, medicine, Immunology and Allergy, Animals, Humans, Cells, Cultured, Ribonucleoprotein, Mice, Inbred BALB C, medicine.diagnostic_test, Citrullination, Fibrinogen, General Medicine, biology.organism_classification, Molecular biology, In vitro, Enzyme Activation, 030104 developmental biology, Sjogren's Syndrome, Gene Expression Regulation, Ribonucleoproteins, Protein-Arginine Deiminases, Protein-Arginine Deiminase Type-4, Cytokines, Inflammation Mediators, lcsh:RC581-607, 030215 immunology, Research Article
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المؤلفون: Adam Thean Chor Leow, Bimo Ario Tejo, Chian Ying Teo, Abu Bakar Salleh, Mohd Basyaruddin Abdul Rahman
المصدر: Chemical biologydrug design. 90(6)
مصطلحات موضوعية: 0301 basic medicine, Circular dichroism, Stereochemistry, Peptide, Biochemistry, Protein Structure, Secondary, 03 medical and health sciences, Inhibitory Concentration 50, 0302 clinical medicine, Protein-Arginine Deiminase Type 4, Drug Discovery, Humans, Amino Acid Sequence, Binding site, Enzyme Inhibitors, Furans, Peptide sequence, IC50, Nuclear Magnetic Resonance, Biomolecular, Pharmacology, chemistry.chemical_classification, Binding Sites, Circular Dichroism, Organic Chemistry, Small molecule, Amino acid, Protein Structure, Tertiary, Molecular Docking Simulation, Kinetics, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Drug Design, Protein-Arginine Deiminases, Molecular Medicine, Protein-Arginine Deiminase Type-4, Peptides
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المؤلفون: Niels Borregaard, Ole E. Sørensen
مصطلحات موضوعية: 0301 basic medicine, Extracellular Traps, Hydrolases, Neutrophils, Autoimmunity, Review, Biology, medicine.disease_cause, 03 medical and health sciences, Protein-Arginine Deiminase Type 4, Extracellular, medicine, Animals, Humans, Autoantibodies, Innate immune system, Citrullination, Thrombosis, General Medicine, Neutrophil extracellular traps, Immunity, Innate, Cell biology, 030104 developmental biology, Histone, Immunology, biology.protein, Protein-Arginine Deiminases, Protein-Arginine Deiminase Type-4
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19Autodeimination of Protein Arginine Deiminase 4 Alters Protein–Protein Interactions but Not Activity
المؤلفون: Jessica L. Slack, Monica Bhatia, Larry E. Jones, Paul R. Thompson
المصدر: Biochemistry. 50:3997-4010
مصطلحات موضوعية: Protein-Arginine N-Methyltransferases, Hydrolases, HL-60 Cells, Histone Deacetylase 1, Biology, SAP30, Biochemistry, Article, Histones, Histone H3, Protein-Arginine Deiminase Type 4, Humans, Protein Interaction Domains and Motifs, Protein-Arginine Deiminases, Histone deacetylase 5, Protein-arginine deiminase, HDAC4, Recombinant Proteins, Enzyme Activation, Repressor Proteins, Histone methyltransferase, Protein-Arginine Deiminase Type-4, Imines, Protein Processing, Post-Translational
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المؤلفون: Miriam A. Shelef, Claus Henrik Nielsen, Dres Damgaard, Mandar Bawadekar, Allan Stensballe, Ladislav Šenolt
المصدر: PLoS ONE, Vol 13, Iss 8, p e0203214 (2018)
Damgaard, D, Bawadekar, M, Senolt, L, Stensballe, A, Shelef, M A & Nielsen, C H 2018, ' Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3 ', PLOS ONE, vol. 13, no. 8, e0203214 . https://doi.org/10.1371/journal.pone.0203214
Damgaard, D, Bawadekar, M, Senolt, L, Stensballe, A, Shelef, M A & Nielsen, C H 2018, ' Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3 ', PLoS ONE, vol. 13, no. 8, e0203214, pp. 1-14 . https://doi.org/10.1371/journal.pone.0203214مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, lcsh:Medicine, In Vitro Techniques, Fibrinogen, Anti-Citrullinated Protein Antibodies, Epitope, Arthritis, Rheumatoid, Histones, 03 medical and health sciences, chemistry.chemical_compound, Histone H3, 0302 clinical medicine, Protein-Arginine Deiminase Type 4, Protein-Arginine Deiminase Type 2, Synovial Fluid, medicine, Citrulline, Humans, lcsh:Science, skin and connective tissue diseases, Serum Albumin, 030203 arthritis & rheumatology, Multidisciplinary, biology, lcsh:R, Citrullination, Anti–citrullinated protein antibody, Hydrogen-Ion Concentration, Molecular biology, Recombinant Proteins, 030104 developmental biology, Histone, chemistry, Phosphopyruvate Hydratase, Protein-Arginine Deiminases, biology.protein, Protein-Arginine Deiminase Type-4, Calcium, lcsh:Q, medicine.drug
وصف الملف: application/pdf