المؤلفون: Grace R. Anderson, Peter S. Winter, Kevin H. Lin, Daniel P. Nussbaum, Merve Cakir, Elizabeth M. Stein, Ryan S. Soderquist, Lorin Crawford, Jim C. Leeds, Rachel Newcomb, Priya Stepp, Catherine Yip, Suzanne E. Wardell, Jennifer P. Tingley, Moiez Ali, Mengmeng Xu, Meagan Ryan, Shannon J. McCall, Autumn J. McRee, Christopher M. Counter, Channing J. Der, Kris C. Wood

المصدر: Cell Reports, Vol 20, Iss 4, Pp 999-1015 (2017)

مصطلحات موضوعية: CRISPR/Cas9, pooled screening, synthetic lethality, KRAS, PIK3CA, SRC, BIM, apoptosis, drug resistance, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717309452; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/a9b233c46180479b811cfec67978789b

المؤلفون: Christopher M. Counter, Autumn J. McRee, Grace R. Anderson, Merve Cakir, Meagan B. Ryan, Catherine Yip, MengMeng Xu, Kevin H. Lin, Channing J. Der, Suzanne E. Wardell, Jennifer P. Tingley, Ryan S. Soderquist, Elizabeth M. Stein, Jim C. Leeds, Priya Stepp, Moiez Ali, Kris C. Wood, Rachel Newcomb, Peter S. Winter, Lorin Crawford, Daniel P. Nussbaum, Shannon J. McCall

المصدر: Cell Reports, Vol 20, Iss 4, Pp 999-1015 (2017)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Mutant, Apoptosis, Synthetic lethality, Biology, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, pooled screening, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Cell Line, Tumor, KRAS, medicine, Humans, BIM, Clustered Regularly Interspaced Short Palindromic Repeats, CRISPR/Cas9, lcsh:QH301-705.5, neoplasms, PI3K/AKT/mTOR pathway, drug resistance, Effector, PIK3CA, Cell cycle, synthetic lethality, 030104 developmental biology, lcsh:Biology (General), Mutation, Cancer research, Signal transduction, Colorectal Neoplasms, SRC, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af542469270383ffd49df483ff8f5d90
https://europepmc.org/articles/PMC5567854/