المؤلفون: Soto Faguás, Carlos Manuel

Thesis Advisors: Saura Antolín, Carlos A. (Carlos Alberto)

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Presenilina, Presenilin, Tau, Neurodegeneració, Neurodegeneración, Ciències de la Salut

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/673848

المؤلفون: Zoltowska, Katarzyna, Das, Utpal, Lismont, Sam, Enzlein, Thomas, Maesako, Masato, Houser, Mei, Franco, Maria, Özcan, Burcu, Gomes Moreira, Diana, Karachentsev, Dmitry, Becker, Ann, Hopf, Carsten, Vilar, Marçal, Berezovska, Oksana, Mobley, William, Chávez-Gutiérrez, Lucía

مصطلحات موضوعية: Alzheimers disease, amyloid beta, amyloid toxicity, biochemistry, chemical biology, gamma-secretase, gamma-secretase inhibition, human, mouse, neuroscience, presenilin, rat, Amyloid Precursor Protein Secretases, Amyloid beta-Peptides, Humans, Alzheimer Disease, Signal Transduction, Animals, Neurons, Mice, Feedback, Physiological, Peptide Fragments, Cell Line

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3494t9df
https://escholarship.org/content/qt3494t9df/qt3494t9df.pdf

المؤلفون: Javier Torrent, Míriam

المساهمون: University/Department: Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular

Thesis Advisors: Saura Antolín, Carlos A. (Carlos Alberto)

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Creixement axonal, Crecimiento axonal, Axon growth, Presenilina, Presenilin, Secretasa, Ciències Experimentals

Time: 616.8

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/666905

المؤلفون: Michno, Wojciech, Bowman, Andrew, Jha, Durga, Minta, Karolina, Ge, Junyue, Koutarapu, Srinivas, Zetterberg, Henrik, Blennow, Kaj, Lashley, Tammaryn, Heeren, Ron M. A., Hanrieder, Jorg

المصدر: ACS Chemical Neuroscience. 15(4):877-888

مصطلحات موضوعية: Alzheimer's disease, beta-amyloid, plaque pathology, neurolipidomics, mass spectrometryimaging, presenilin 1

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-531634
https://doi.org/10.1021/acschemneuro.4c00006
https://uu.diva-portal.org/smash/get/diva2:1872181/FULLTEXT01.pdf

المؤلفون: Florian Perrin, Lauren C. Anderson, Shane P. C. Mitchell, Priyanka Sinha, Yuliia Turchyna, Masato Maesako, Mei C. Q. Houser, Can Zhang, Steven L. Wagner, Rudolph E. Tanzi, Oksana Berezovska

المصدر: Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-17 (2024)

مصطلحات موضوعية: Alzheimer’s disease, Presenilin 1, EAAT2, GLT-1, Glutamate transport, Hyperactivity, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/ca2040f77bea44028933d446ce3fab62

المؤلفون: Karunungan, Krystal, Garza, Rachel H, Grodzki, Ana Cristina, Holt, Megan, Lein, Pamela J, Chandrasekaran, Vidya

مصطلحات موضوعية: Biomedical and Clinical Sciences, Medical Physiology, Neurosciences, Alzheimer's Disease, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Aging, Dementia, Acquired Cognitive Impairment, Brain Disorders, Neurodegenerative, 1.1 Normal biological development and functioning, Neurological, Rats, Animals, Bone Morphogenetic Protein 7, Amyloid Precursor Protein Secretases, Dendrites, Cells, Cultured, Neurons, & gamma, -Secretase, DAPT, LY-411575, BMS-299897, Dendrite, Bone morphogenetic proteins, Sympathetic neurons, Presenilin, γ-Secretase, Clinical Sciences, Pharmacology and Pharmaceutical Sciences, Neurology & Neurosurgery, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5sq0t98w
https://escholarship.org/content/qt5sq0t98w/qt5sq0t98w.pdf

المؤلفون: Ahmad Sajjad, Jinfei Mei, Chuanbo Wang, Hongqi Ai

المصدر: ChemPhysMater, Vol 3, Iss 3, Pp 303-313 (2024)

مصطلحات موضوعية: Five lipids, Gamma secretase, Presenilin, Nicastrin, Effect of lipid on GS, Chemistry, QD1-999, Physics, QC1-999

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772571524000184; https://doaj.org/toc/2772-5715

URL الوصول: https://doaj.org/article/9c05b2fe324843b680203a1073144bcc

المؤلفون: Mendivil-Perez, Miguel, Velez-Pardo, Carlos, Lopera, Francisco, Kosik, Kenneth, Jimenez-Del-Rio, Marlene

المصدر: International Journal of Molecular Sciences. 24(10)

مصطلحات موضوعية: Alzheimer, E280a, apoptosis, iPSCs, mesenchymal stromal, mutant, presenilin, Humans, Induced Pluripotent Stem Cells, Alzheimer Disease, Cholinergic Neurons, Mesenchymal Stem Cells, Cholinergic Agents, Presenilin-1

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4769h3qf
https://escholarship.org/content/qt4769h3qf/qt4769h3qf.pdf

المؤلفون: Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Mei CQ Houser, Maria Luisa Franco, Burcu Özcan, Diana Gomes Moreira, Dmitry Karachentsev, Ann Becker, Carsten Hopf, Marçal Vilar, Oksana Berezovska, William Mobley, Lucía Chávez-Gutiérrez

المصدر: eLife, Vol 12 (2024)

مصطلحات موضوعية: Alzheimer's disease, gamma-secretase, presenilin, amyloid beta, amyloid toxicity, gamma-secretase inhibition, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/90690; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/2631ca395939430b962c9f2eb0249faf

المؤلفون: Priyanka Sinha, Yuliia Turchyna, Shane Patrick Clancy Mitchell, Michael Sadek, Gokce Armagan, Florian Perrin, Masato Maesako, Oksana Berezovska

المصدر: Cells, Vol 13, Iss 19, p 1600 (2024)

مصطلحات موضوعية: Alzheimer’s disease, presenilin 1, glutamate transporter 1, amyloid β, GLT1/PS1 interaction, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/19/1600; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/3969f56997554ee5b81d014eef26075a

المؤلفون: Liliia Kushnireva, Menahem Segal, Eduard Korkotian

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 1, p 578 (2024)

مصطلحات موضوعية: CCCP, carbonyl cyanide m chlorophenyl hydrazone, calcium, presenilin 1, mutant presenilin 1, processes, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/1/578; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/2d3ebb4c36d54e55a8cb3089b6f58559

الاتاحة: https://doi.org/10.3390/ijms25010578
https://doaj.org/article/2d3ebb4c36d54e55a8cb3089b6f58559

المؤلفون: Konstantinidis, Evangelos, Molisak, Agnieszka, Perrin, Florian, Streubel-Gallasch, Linn, Fayad, Sarah, Kim, Daniel Y., Petri, Karl, Aryee, Martin J., Aguilar, Ximena, György, Bence, Giedraitis, Vilmantas, Joung, J. Keith, Pattanayak, Vikram, Essand, Magnus, Erlandsson, Anna, Berezovska, Oksana, Ingelsson, Martin

المصدر: Molecular Therapy Nucleic Acids. 28:450-461

مصطلحات موضوعية: MT, RNA/DNA editing, Alzheimer’s disease, presenilin 1, amyloid-β, fibroblasts, CRISPR-Cas9, gene editing, protein conformation, off-target effects

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-475572
https://doi.org/10.1016/j.omtn.2022.03.022
https://uu.diva-portal.org/smash/get/diva2:1664159/FULLTEXT01.pdf

المؤلفون: Gayane Hrachia Buniatian, Ute Schwinghammer, Roman Tremmel, Holger Cynis, Thomas S. Weiss, Ralf Weiskirchen, Volker M. Lauschke, Sonia Youhanna, Isbaal Ramos, Maria Valcarcel, Torgom Seferyan, Jens‐Ulrich Rahfeld, Vera Rieckmann, Kathrin Klein, Marine Buadze, Victoria Weber, Valentina Kolak, Rolf Gebhardt, Scott L. Friedman, Ulrike C. Müller, Matthias Schwab, Lusine Danielyan

المصدر: Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)

مصطلحات موضوعية: 5xFAD, eNOS, neprilysin, presenilin, TGFβ, VEGF, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2198-3844

URL الوصول: https://doaj.org/article/a502efb1c1864047b669d0f146231d64

المؤلفون: Littau, Jessica Lisa

مصطلحات موضوعية: Vascular pathology, Presenilin 1, Familial Alzheimer's disease, 500: Naturwissenschaften, ddc:500:

URL الوصول: http://nbn-resolving.de/urn:nbn:de:gbv:18-ediss-121763
https://ediss.sub.uni-hamburg.de/handle/ediss/11193

المؤلفون: Anxo Manuel Minguillón Pereiro, Beatriz Quintáns Castro, Alberto Ouro Villasante, José Manuel Aldrey Vázquez, Julia Cortés Hernández, Marta Aramburu-Núñez, Manuel Arias Gómez, Isabel Jiménez Martín, Tomás Sobrino, Juan Manuel Pías-Peleteiro

المصدر: Biomedicines, Vol 12, Iss 8, p 1881 (2024)

مصطلحات موضوعية: Alzheimer’s disease, frontotemporal dementia, presenilin 2, phenocopies, white matter hyperintensities, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/8/1881; https://doaj.org/toc/2227-9059

URL الوصول: https://doaj.org/article/76985eca25c14df980206ab1554793b7

المؤلفون: Suwakon Wongjaikam, Chutikorn Nopparat, Parichart Boontem, Jiraporn Panmanee, Nopporn Thasana, Mayuri Shukla, Piyarat Govitrapong

المصدر: Biology, Vol 13, Iss 7, p 518 (2024)

مصطلحات موضوعية: Huperzine A, Alzheimer’s disease, amyloid beta, amyloid precursor protein, β-site amyloid precursor protein cleaving enzyme 1, presenilin 1, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2079-7737/13/7/518; https://doaj.org/toc/2079-7737

URL الوصول: https://doaj.org/article/334d4a60dd96447fb1f5aee0a4e01d3a

المؤلفون: Wei Wei, Hang Sun, Bingwei Yang, Chengyu Zhu, Erqun Song, Yang Song

مصطلحات موضوعية: Biochemistry, Molecular Biology, Neuroscience, Pharmacology, Mental Health, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, remains largely unclear, related protein 1, related gene expressions, presenilin 1 genes, potential risk factors, plasma apolipoprotein e, accelerating alzheimer ’, 1 – 42, density lipoprotein receptor, using apoe knockout, sinps partially relieves, elevated ad symptoms, transport receptor, study offered, sinps upregulate, sinps covered, silica nps, ps1 mice, intravenous injection, increasing nanoparticle, challenged app, biomedical field, ad pathology

Relation: https://figshare.com/articles/journal_contribution/Silica_Nanoparticle_Exposure_Implicates_Amyloid_1_42_Inbound_and_the_Accelerating_Alzheimer_s_Disease_Progression_in_Mice_Overexpressing_Mutated_Forms_of_Human_Amyloid_Precursor_Protein_and_Presenilin_1_Genes/24967981

الاتاحة: https://doi.org/10.1021/acs.chemrestox.3c00378.s001
https://figshare.com/articles/journal_contribution/Silica_Nanoparticle_Exposure_Implicates_Amyloid_1_42_Inbound_and_the_Accelerating_Alzheimer_s_Disease_Progression_in_Mice_Overexpressing_Mutated_Forms_of_Human_Amyloid_Precursor_Protein_and_Presenilin_1_Genes/24967981

المؤلفون: Serneels, L, Bammens, L, Zwijsen, A, Tolia, A, Chávez-Gutiérrez, L, De Strooper, B

المصدر: Journal of Biological Chemistry , 300 (1) , Article 105533. (2024)

مصطلحات موضوعية: Alzheimer, PSENEN, presenilin, γ-secretase

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10191104/1/1-s2.0-S0021925823025619-main.pdf; https://discovery.ucl.ac.uk/id/eprint/10191104/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10191104/1/1-s2.0-S0021925823025619-main.pdf
https://discovery.ucl.ac.uk/id/eprint/10191104/

المؤلفون: De Strooper, Bart, Karran, Eric

المصدر: The EMBO Journal (2024) (In press).

مصطلحات موضوعية: Alzheimer, Cancer, Gamma-secretase-modulator, Presenilin, γ-Secretase Allosteric Stabilizer

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10188664/1/de-strooper-karran-2024-new-precision-medicine-avenues-to-the-prevention-of-alzheimer-s-disease-from-insights-into-the.pdf; https://discovery.ucl.ac.uk/id/eprint/10188664/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10188664/1/de-strooper-karran-2024-new-precision-medicine-avenues-to-the-prevention-of-alzheimer-s-disease-from-insights-into-the.pdf
https://discovery.ucl.ac.uk/id/eprint/10188664/

المؤلفون: Michno, Wojciech, Bowman, Andrew, Jha, Durga, Minta, Karolina, Ge, Junyue, Koutarapu, Srinivas, Zetterberg, Henrik, Blennow, Kaj, Lashley, Tammaryn, Heeren, Ron MA, Hanrieder, Jörg

المصدر: ACS Chemical Neuroscience (2024) (In press).

مصطلحات موضوعية: Alzheimer’s disease, mass spectrometry imaging, neurolipidomics, plaque pathology, presenilin 1, β-amyloid

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/10186743/1/Spatial%20Neurolipidomics.pdf; https://discovery.ucl.ac.uk/id/eprint/10186743/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10186743/1/Spatial%20Neurolipidomics.pdf
https://discovery.ucl.ac.uk/id/eprint/10186743/