نتائج البحث - "Pre-steady-state Kinetics"

المساهمون: Institute of Chemical Biology and Fundamental Medicine Novosibirsk, Russia (ICBFM SB RAS), Siberian Branch of the Russian Academy of Sciences (SB RAS), International Tomography Center, SB RAS, 630090, Novosibirsk, Russia, Intégrité du génome et cancers (IGC), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Al-Farabi Kazakh National University Almaty (KazNU), Novosibirsk State University (NSU)

المصدر: ISSN: 1568-7864.

مصطلحات موضوعية: DNA repair Apurinic/apyrimidinic endonuclease DNA-protein interaction Protein-protein interaction Damaged DNA transfer Conformational change Fluorescence Pre-steady-state kinetics, [SDV]Life Sciences [q-bio]

الاتاحة: https://hal.science/hal-04289551
https://hal.science/hal-04289551v1/document
https://hal.science/hal-04289551v1/file/Bakman%20AS_Fluorescently%20labeled%20APE1%20reveals%20effects%20of%20Pol-beta%20on%20the%20APE1%E2%80%93DNA%20interaction_DNAREP_103450.pdf
https://doi.org/10.1016/j.dnarep.2023.103450

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4

Academic Journal

The Impact of Human DNA Glycosylases on the Activity of DNA Polymerase β toward Various Base Excision Repair Intermediates

المؤلفون: Bakman, Artemiy, S, Boichenko, Stanislav, S, Kuznetsova, Aleksandra, A, Ishchenko, Alexander, A, Saparbaev, Murat, Kuznetsov, Nikita, A

المساهمون: Institute of Chemical Biology and Fundamental Medicine Novosibirsk, Russia (ICBFM SB RAS), Siberian Branch of the Russian Academy of Sciences (SB RAS), Novosibirsk State University (NSU), Intégrité du génome et cancers (IGC), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 1661-6596.

مصطلحات موضوعية: DNA repair, apurinic/apyrimidinic endonuclease, DNA-protein interaction, protein-protein interaction, damaged DNA transfer, conformational change, fluorescence, pre-steady-state kinetics, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN]

الاتاحة: https://hal.science/hal-04289584
https://hal.science/hal-04289584v1/document
https://hal.science/hal-04289584v1/file/Bakman%20AS_The%20Impact%20of%20Human%20DNA%20Glycosylases%20on%20the%20Activity%20of%20Pol-beta%20toward%20Various%20BER%20Intermediates%20_MDPI%20MolSci2023_reprint.pdf
https://doi.org/10.3390/ijms24119594

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5

Academic Journal

Conformational Dynamics of Biopolymers in the Course of Their Interaction: Multifaceted Approaches to the Analysis by the Stopped-Flow Technique with Fluorescence Detection

المؤلفون: Nikita A. Kuznetsov

المصدر: Photonics ; Volume 10 ; Issue 9 ; Pages: 1033

مصطلحات موضوعية: enzymatic activity, mechanism, catalysis, pre-steady-state kinetics, thermodynamics, mutational analysis, fluorescence, DNA damage, base excision repair, DNA glycosylase, AP endonuclease

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/photonics10091033

الاتاحة: https://doi.org/10.3390/photonics10091033

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6

A structurally heterogeneous transition state underlies coupled binding and folding of disordered proteins

المؤلفون: Karlsson, Elin, Andersson, Eva, Dogan, Jakob, Gianni, Stefano, Jemth, Per, Camilloni, Carlo

المصدر: Journal of Biological Chemistry. 294(4):1230-1239

مصطلحات موضوعية: intrinsically disordered protein, pre-steady-state kinetics, protein folding, protein-protein interaction, molecular dynamics

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-166791
https://doi.org/10.1074/jbc.RA118.005854

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7

Academic Journal

Kinetic Features of 3′–5′–Exonuclease Activity of Apurinic/Apyrimidinic Endonuclease Apn2 from Saccharomyces cerevisiae

المؤلفون: Kuznetsova, Aleksandra, A, Gavrilova, Anastasia, A, Ishchenko, Alexander, A, Saparbaev, Murat, Fedorova, Olga, S, Kuznetsov, Nikita, A

المساهمون: Institute of Chemical Biology and Fundamental Medicine Novosibirsk, Russia (ICBFM SB RAS), Siberian Branch of the Russian Academy of Sciences (SB RAS), Intégrité du génome et cancers (IGC), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Novosibirsk State University (NSU), Ministry of Science and Higher Education of the Russian Federation, agreement No. 075-15-2022-263, Electricité de France (RB 2020-02 and RB 2021-05), Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan No. AP08856811, Fondation ARC grant PJA-2021060003796, ANR-22-CE12-0034,MITOMUTREP,Étude de la base physique de l'héritage des brins d'ADN dans l'ADN mitochondrial humain(2022)

المصدر: ISSN: 1661-6596.

الاتاحة: https://hal.science/hal-04289790
https://hal.science/hal-04289790v1/document
https://hal.science/hal-04289790v1/file/Kuznetsova%20AA_Kinetic%20Features%20of%203%EA%9E%8C-5%27-Exonuclease%20Activity%20of%20AP%20Endonuclease%20Apn2%20from%20S.%20cerevisiae_IJMS2022_reprint.pdf
https://doi.org/10.3390/ijms232214404

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8

Academic Journal

Pre-steady-state kinetic and mutational insights into mechanisms of endo- and exonuclease DNA processing by mutant forms of human AP endonuclease

المؤلفون: Bakman, Artemiy, S, Ishchenko, Alexander, A, Saparbaev, Murat, Fedorova, Olga, S, Kuznetsov, Nikita, A

المساهمون: Institute of Chemical Biology and Fundamental Medicine Novosibirsk, Russia (ICBFM SB RAS), Siberian Branch of the Russian Academy of Sciences (SB RAS), Intégrité du génome et cancers (IGC), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Novosibirsk State University (NSU)

المصدر: ISSN: 0304-4165.

مصطلحات موضوعية: DNA repair, apurinic/apyrimidinic endonuclease, DNA‐protein interaction, conformational change, substrate recognition, active site, fluorescence, pre‐steady‐state kinetics, [SDV]Life Sciences [q-bio]

Relation: hal-04289761; https://hal.science/hal-04289761; https://hal.science/hal-04289761/document; https://hal.science/hal-04289761/file/Bakman%20AS_Pre-steady-state%20kinetic%20%26%20mutational%20insights%20into%20mechanisms%20of%20endo-%20%26%20exonuclease%20activities%20of%20APE1_BBA2022_PDF.pdf

الاتاحة: https://hal.science/hal-04289761
https://hal.science/hal-04289761/document
https://hal.science/hal-04289761/file/Bakman%20AS_Pre-steady-state%20kinetic%20%26%20mutational%20insights%20into%20mechanisms%20of%20endo-%20%26%20exonuclease%20activities%20of%20APE1_BBA2022_PDF.pdf
https://doi.org/10.1016/j.bbagen.2022.130198

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9

Academic Journal

The Kinetic Mechanism of 3′-5′ Exonucleolytic Activity of AP Endonuclease Nfo from E. coli

المؤلفون: Svetlana I. Senchurova, Aleksandra A. Kuznetsova, Alexander A. Ishchenko, Murat Saparbaev, Olga S. Fedorova, Nikita A. Kuznetsov

المصدر: Cells; Volume 11; Issue 19; Pages: 2998

مصطلحات موضوعية: DNA repair, apurinic/apyrimidinic endonuclease, pre-steady-state kinetics, fluorescence

وصف الملف: application/pdf

Relation: Cell Signaling; https://dx.doi.org/10.3390/cells11192998

الاتاحة: https://doi.org/10.3390/cells11192998

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10

Academic Journal

Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy

المؤلفون: Lyubov Yu. Kanazhevskaya, Denis A. Smyshliaev, Nadezhda A. Timofeyeva, Alexander A. Ishchenko, Murat Saparbaev, Nikita A. Kuznetsov, Olga S. Fedorova

المصدر: Molecules; Volume 27; Issue 15; Pages: 4960

مصطلحات موضوعية: DNA repair, dioxygenase ALKBH2, DNA methylation, conformational dynamics, fluorescent spectroscopy, pre-steady-state kinetics, stopped-flow, aminopurine, FRET analysis

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Physical Chemistry; https://dx.doi.org/10.3390/molecules27154960

الاتاحة: https://doi.org/10.3390/molecules27154960

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11

Academic Journal

Pre-Steady-State Kinetics of the SARS-CoV-2 Main Protease as a Powerful Tool for Antiviral Drug Discovery

المؤلفون: Maria Yu. Zakharova, Alexandra A. Kuznetsova, Victoria I. Uvarova, Anastasiia D. Fomina, Liubov I. Kozlovskaya, Elena N. Kaliberda, Inna N. Kurbatskaia, Ivan V. Smirnov, Anatoly A. Bulygin, Vera D. Knorre, Olga S. Fedorova, Alexandre Varnek, Dmitry I. Osolodkin, Aydar A. Ishmukhametov, Alexey M. Egorov, Alexander G. Gabibov, Nikita A. Kuznetsov

المصدر: Frontiers in Pharmacology, Vol 12 (2021)

مصطلحات موضوعية: SARS-CoV-2, main protease, pre-steady-state kinetics, substrate cleavage, inhibitor binding, molecular docking, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.773198/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/d34b9bc2a37f410db93fca2863eda72a

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12

Academic Journal

The reaction mechanism of methyl-coenzyme M reductase: How an enzyme enforces strict binding order

المساهمون: Ragsdale, Stephen [Univ. of Michigan, Ann Arbor, MI (United States)]

المصدر: Journal of Biological Chemistry; 290; 15

وصف الملف: Medium: ED; Size: p. 9322-9334

URL الوصول: http://www.osti.gov/scitech/servlets/purl/1348414

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13

Academic Journal

Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase η

المساهمون: Guengerich, F. [Vanderbilt Univ., Nashville, TN (United States). School of Medicine. Center in Molecular Toxicology. Dept. of Biochemistry]

المصدر: Journal of Biological Chemistry; 290; 13

وصف الملف: Medium: ED; Size: p. 8028-8038

URL الوصول: http://www.osti.gov/scitech/servlets/purl/1178830

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14

Academic Journal

Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair

المؤلفون: Bakman, Artemiy, Boichenko, Stanislav, Kuznetsova, Aleksandra, Ishchenko, Alexander, Saparbaev, Murat, Kuznetsov, Nikita

المساهمون: Institute of Chemical Biology and Fundamental Medicine Novosibirsk, Russia (ICBFM SB RAS), Siberian Branch of the Russian Academy of Sciences (SB RAS), Novosibirsk State University (NSU), Intégrité du génome et cancers (IGC), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut Gustave Roussy (IGR)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Electricite de France EDF RB 2020-02 and RB 2021-05, Fondation ARC (PJA-2021060003796)

المصدر: ISSN: 0300-9084.

مصطلحات موضوعية: Apurinic/apyrimidinic endonuclease, Conformational change, DNA repair, DNA-protein interaction, Damaged-DNA transfer, Fluorescence, Pre-steady-state kinetics, Protein-protein interaction, [SDV]Life Sciences [q-bio]