المؤلفون: Mahesh Kumar Mone, Summon Koul, Sophie Roy, Anil M. Deshpande, Sachin Kandalkar, Ravi P. Nargund, Jayasagar Gundu, Anita Chugh, Michael P. Graziano, Doris F. Cully, Tian-Quan Cai, Prasun K. Chakravarty, Samir Vyas, Sheo B. Singh, Joseph P. Vacca, Umesh Prasad Singh, Pradeep Rangrao Patil, Ashwin Meru, Dinesh A. Barawkar, Goraksha Khose, Shubhangi Bhosale, Anish Bandyopadhyay, Venkata P. Palle, Kasim A. Mookhtiar, Samuel D. Wright, Siddhartha De

المصدر: Bioorganic & Medicinal Chemistry Letters. 22:4341-4347

مصطلحات موضوعية: Candidate gene, Stereochemistry, Carboxylic acid, Clinical Biochemistry, Carboxylic Acids, Drug Evaluation, Preclinical, Pharmaceutical Science, Thiophenes, Pyrazole, Kidney, Biochemistry, Gene product, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Humans, Structure–activity relationship, Computer Simulation, Enzyme Inhibitors, Binding site, Molecular Biology, chemistry.chemical_classification, Oxidase test, Binding Sites, Organic Chemistry, Kidney metabolism, Protein Structure, Tertiary, Rats, Alcohol Oxidoreductases, Liver, chemistry, Pyrazoles, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a13402479c10b79820ca6de2def8846
https://doi.org/10.1016/j.bmcl.2012.05.020

المؤلفون: Gagan Kukreja, Sophie Roy, Siddhartha De, Anita Chugh, Samuel D. Wright, Ravi P. Nargund, Suhas Tambe, Yogesh D. Shejul, Deepak B. Salunke, Michael P. Graziano, Jayasagar Gundu, Santosh Kurhade, Debnath Bhuniya, Kasim A. Mookhtiar, Sheo B. Singh, Joseph P. Vacca, Dhananjay N. Umrani, Bhavesh Dave, Minakshi Naykodi, Tian-Quan Cai, Sreemita Majumdar, Doris F. Cully, Prasun K. Chakravarty, Nadim S. Shaikh, Venkata P. Palle, Srinivasa B. Reddy, Prasad Shitole

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:3596-3602

مصطلحات موضوعية: Male, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Pharmacology, Biochemistry, Receptors, G-Protein-Coupled, Small Molecule Libraries, Inhibitory Concentration 50, In vivo, Drug Discovery, Succinate receptor 1, Animals, Structure–activity relationship, Rats, Wistar, Receptor, Molecular Biology, G protein-coupled receptor, Molecular Structure, Chemistry, Organic Chemistry, Antagonist, Biological activity, Small molecule, Rats, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4824806ea8fdce58ee36cf56fffe0be4
https://doi.org/10.1016/j.bmcl.2011.04.091

المؤلفون: Brande S. Williams, Mathew J. Wyvratt, Sriram Tyagarajan, Vivien A. Warren, Catherine Abbadie, Brett Taylor, William J. Martin, Xiaohua Li, William H. Parsons, Nina Jochnowitz, Erin McGowan, Sanjeev Kumar, Ann E. Weber, Gregory J. Kaczorowski, Michael H. Fisher, Bishan Zhou, John P. Felix, Tracy Klatt, McHardy M. Smith, Birgit T. Priest, Prasun K. Chakravarty, Kathryn A. Lyons, Joseph L. Duffy, Ronsar Eid, Maria L. Garcia, Richard M. Brochu

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:7479-7482

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Analgesic, Drug Evaluation, Preclinical, Biphenyl derivatives, Pharmaceutical Science, Motor Activity, Pyrazole, Pharmacology, Biochemistry, Sodium Channels, Mice, chemistry.chemical_compound, Dogs, Sodium channel blocker, Drug Discovery, Animals, Humans, Spinal nerve ligation, Molecular Biology, Biphenyl Compounds, Organic Chemistry, Metabolic stability, Rats, Liver metabolism, chemistry, Neuropathic pain, Microsomes, Liver, Neuralgia, Pyrazoles, Molecular Medicine, Sodium Channel Blockers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44809e16a6cd04e26b06d5a57716c59e
https://doi.org/10.1016/j.bmcl.2010.10.017

المؤلفون: Peter T. Meinke, Dennis M. Schmatz, L.M. Gregory, Steven L. Colletti, Prasun K. Chakravarty, Steve Salva, Matthew J. Wyvratt, Wesley L. Shoop, Michelle B. Ayer, Chunshi Li, Thomas L. Shih, Michelle Zakson-Aiken, Dong Ok, Michael H. Fisher

المصدر: Bioorganic & Medicinal Chemistry Letters. 12:1751-1754

مصطلحات موضوعية: Insecticides, Indoles, Screening test, medicine.drug_class, Stereochemistry, Carboxylic acid, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Ectoparasitic Infestations, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Polycyclic compound, Drug Discovery, medicine, Side chain, Animals, Molecular Biology, Biological evaluation, chemistry.chemical_classification, Chemistry, Organic Chemistry, Chemical modification, Stereoisomerism, Lactam, Siphonaptera, Molecular Medicine, Cattle

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05d69f58a48520240ded8208c76c915
https://doi.org/10.1016/s0960-894x(02)00284-6

المؤلفون: Christine Snedden, Peter T. Meinke, Steve Salva, Matthew J. Wyvratt, Prasun K. Chakravarty, Thomas L. Shih, Sriram Tyagarajan, Michael H. Fisher

المصدر: Organic Letters. 4:1291-1294

مصطلحات موضوعية: chemistry.chemical_classification, Aldehydes, Insecticides, Indoles, Oxidative degradation, Carboxylic acid, Organic Chemistry, Carboxylic Acids, Oxidation reduction, Biochemistry, Aldehyde, chemistry, Nodulisporic acid A, Side chain, Organic chemistry, Indicators and Reagents, Physical and Theoretical Chemistry, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b22822993812eede0e7589d2f3a7ae2
https://doi.org/10.1021/ol025766d

المؤلفون: Sriram Tyagarajan, Prasun K. Chakravarty

المصدر: Tetrahedron Letters. 46:7889-7891

مصطلحات موضوعية: Formamide, chemistry.chemical_compound, chemistry, Aryl, Organic Chemistry, Drug Discovery, Microwave irradiation, Organic chemistry, General Medicine, Photochemistry, Biochemistry, High yielding, Microwave

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2d672b4b9cd08ca7b7e3b54a45b803
https://doi.org/10.1016/j.tetlet.2005.09.094

المؤلفون: Catherine Abbadie, Vivien A. Warren, Xiaohua Li, James B Herrington, Gregory J. Kaczorowski, Shruti Mistry, Feng Ye, Andrew M. Swensen, Prasun K. Chakravarty, Rodolfo Haedo, Kathryn A. Lyons, Owen B. McManus, Randal M. Bugianesi, Mitchell D. Green, Shao Pengcheng Patrick, Maria L. Garcia, Shu-Yu Sun, McHardy M. Smith, Erin McGowan, Nina Jochnowitz, Joseph L. Duffy, Ge Dai

مصطلحات موضوعية: chemistry.chemical_classification, Trifluoromethyl, business.industry, Metabolite, Organic Chemistry, Substituent, Biochemistry, Combinatorial chemistry, Sulfonamide, Sulfone, chemistry.chemical_compound, chemistry, Drug Discovery, Potency, Medicine, Bioisostere, Benzamide, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a14af3d556993551af77251b7d66937
https://europepmc.org/articles/PMC4027232/

المؤلفون: Prasun K. Chakravarty, Richard W. Ransom

المصدر: Current Pharmaceutical Design. 1:317-324

مصطلحات موضوعية: Pharmacology, Drug Discovery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8bd7f57a3d72d7b8bdb0d0ed2e4f1bab
https://doi.org/10.2174/1381612801666220919145004

المؤلفون: Prasun K. Chakravarty

المصدر: Expert Opinion on Therapeutic Patents. 5:431-458

مصطلحات موضوعية: Pharmacology, Agonist, medicine.medical_specialty, biology, business.industry, medicine.drug_class, Calcium channel, Vasodilation, Angiotensin-converting enzyme, General Medicine, Angiotensin II, Potassium channel, Endocrinology, Internal medicine, Drug Discovery, Renin–angiotensin system, biology.protein, Medicine, business, Receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dcdde35f1c2f40dcf92eb2781ff952cf
https://doi.org/10.1517/13543776.5.5.431

المؤلفون: Robert A. Gabel, Theodore P. Broten, Gloria J. Zingaro, Linda W. Schaffer, Peter K. S. Siegl, Arthur A. Patchett, Terry W. Schorn, William J. Greenlee, Prasun K. Chakravarty, Elizabeth M. Naylor, Salah D. Kivlighn

المصدر: American Journal of Hypertension. 8:58-66

مصطلحات موضوعية: medicine.medical_specialty, Angiotensin II receptor type 1, biology, medicine.drug_class, business.industry, Antagonist, Angiotensin-converting enzyme, Angiotensin II receptor antagonist, Pharmacology, Receptor antagonist, Angiotensin II, Endocrinology, Losartan, Internal medicine, Internal Medicine, medicine, biology.protein, Enalapril, business, hormones, hormone substitutes, and hormone antagonists, circulatory and respiratory physiology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9f55083766855f91ccf77204abbefbc5
https://doi.org/10.1016/0895-7061(94)00169-c

المؤلفون: Xiaohua Li, Shao Pengcheng Patrick, Joseph L. Duffy, Rodolfo Haedo, Mitchell D. Green, Prasun K. Chakravarty, Gregory J. Kaczorowski, Maria L. Garcia, Ge Dai, Owen B. McManus, Kathryn A. Lyons, Shu-Yu Sun, Andrew M. Swensen, Nina Jochnowitz, Erin McGowan, Deepu J Varughese, Vivien A. Warren, Feng Ye, Catherine Abbadie, James B Herrington, Randal M. Bugianesi, Shruti Mistry, McHardy M. Smith

المصدر: Journal of medicinal chemistry. 55(22)

مصطلحات موضوعية: Patch-Clamp Techniques, Metabolite, Pharmacology, Rats, Sprague-Dawley, chemistry.chemical_compound, Mice, Calcium Channels, N-Type, Dogs, Piperidines, Drug Discovery, medicine, Animals, Humans, Tissue Distribution, Ion channel, Cells, Cultured, Inflammation, Mice, Knockout, Sulfonamides, Voltage-dependent calcium channel, Chemistry, Calcium channel, Sulfonamide (medicine), Chronic pain, medicine.disease, Calcium Channel Blockers, Rats, Allodynia, Hyperalgesia, Microsomes, Liver, Molecular Medicine, Neuralgia, medicine.symptom, Chronic Pain, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894dc35e10efc8859a417daae4f28405
https://pubmed.ncbi.nlm.nih.gov/23098566

المؤلفون: Tsing-B. Chen, Kristie A. Faust, Elizabeth M. Naylor, Bradley V. Clineschmidt, Prasun K. Chakravarty, Victor J. Lotti, Robert J. Bendesky, Stacey A. O'Malley, Paul J. Kling, Raymond S.L. Chang, Arthur A. Patchett, William J. Greenlee

المصدر: Drug Development Research. 32:161-171

مصطلحات موضوعية: Agonist, medicine.medical_specialty, Angiotensin II receptor type 1, Aldosterone, medicine.drug_class, Antagonist, Molecular biology, Angiotensin II, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, Drug Discovery, Renin–angiotensin system, medicine, Receptor, IC50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::68303a85da0e134d25fe0d985f25b245
https://doi.org/10.1002/ddr.430320306

المؤلفون: L.W. Schaffer, Victor J. Lotti, Prasun K. Chakravarty, Wallace T. Ashton, Arthur A. Patchett, Tsing-Bau Chen, K. L. Flanagan, Salah D. Kivlighn, Elizabeth M. Naylor, W.J. Greenlee, Robert J. Bendesky, Linda L. Chang, Peter K. S. Siegl, R. S. L. Chang, Terry W. Schorn, Kristie A. Faust, Gloria J. Zingaro, Paul J. Kling

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:115-120

مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Sulfonamide (medicine), Pharmaceutical Science, Pharmacology, Biochemistry, Angiotensin II, Chemical synthesis, chemistry.chemical_compound, Orally active, chemistry, Oral administration, In vivo, Drug Discovery, medicine, Triazole derivatives, Molecular Medicine, Tetrazole, Molecular Biology, hormones, hormone substitutes, and hormone antagonists, circulatory and respiratory physiology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::720a97dfb54ac5c0536c2b9ce2534228
https://doi.org/10.1016/s0960-894x(01)81132-x

المؤلفون: Gloria J. Zingaro, Salah D. Kivlighn, Peter K.S. Siegel, Raymond S.L. Chang, Victor J. Lotti, Robert A. Strelitz, Arthur A. Patchett, William J. Greenlee, Terry W. Schorn, Prasun K. Chakravarty, Tsing-Bau Chen

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:75-80

مصطلحات موضوعية: chemistry.chemical_classification, Angiotensin receptor, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biological activity, Biochemistry, Combinatorial chemistry, Angiotensin II, Sulfonamide, chemistry.chemical_compound, chemistry, In vivo, Drug Discovery, Molecular Medicine, Tetrazole, Receptor, Molecular Biology, Quinazolinone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e58f370e2b9c602ee4796a2fa006fe75
https://doi.org/10.1016/s0960-894x(01)81125-2

المؤلفون: Gloria J. Zingaro, William J. Greenlee, Tsing-Bau Chen, Kristie A. Faust, Pancras C. Wong, Ruth R. Wexler, Victor J. Lotti, Peter K. S. Siegl, Raymond S.L. Chang, Prasun K. Chakravarty, Elizabeth M. Naylor, Salah D. Kivlighn, Colleen A. Costello, Arthur A. Patchett, David J. Carini

المصدر: Bioorganic & Medicinal Chemistry Letters. 4:69-74

مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Angiotensin II, In vitro, Sulfonamide, chemistry.chemical_compound, chemistry, In vivo, Biological property, Drug Discovery, cardiovascular system, Molecular Medicine, Imidazole, lipids (amino acids, peptides, and proteins), Tetrazole, Molecular Biology, hormones, hormone substitutes, and hormone antagonists, circulatory and respiratory physiology, Binding affinities

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2f1bd5f8936506268fac7d94f6e8eea2
https://doi.org/10.1016/s0960-894x(01)81124-0

المؤلفون: Michael P. Graziano, Anish Bandyopadhyay, Goraksha Khose, Chandrasekhar Koduru, Venkata P. Palle, Doris F. Cully, Sophie Roy, Sanjay Niranjan, Anil M. Deshpande, Pradeep Rangrao Patil, Prasun K. Chakravarty, Ashwin Meru, Shubhangi Bhosale, Sachin Kandalkar, Ravi P. Nargund, Koshu Mahajan, Chandrashekhar Athare, Sheo B. Singh, Anita Chugh, Abir L. Banerjee, Joseph P. Vacca, Umesh Prasad Singh, Siddhartha De, Sudit S. Mukhopadhyay, Tian-Quan Cai, Sumit Chaudhary, Kasim A. Mookhtiar, Jayasagar Gundu, Samuel D. Wright, Dinesh A. Barawkar, Summon Koul

المصدر: ACS medicinal chemistry letters. 2(12)

مصطلحات موضوعية: Candidate gene, Oxidase test, Long-chain L-2-hydroxy acid oxidase, business.industry, Liver and kidney, Organic Chemistry, Pharmacology, Doca salt, Biochemistry, Blood pressure, Pharmacokinetics, In vivo, Drug Discovery, Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203a3b01efb237467dd644b7518a2e39
https://pubmed.ncbi.nlm.nih.gov/24900281

المؤلفون: R. Simpson, Prasun K. Chakravarty, R. Chen, Ralph A. Rivero, A. Rosegay, W.J. Greenlee

المصدر: Bioorganic & Medicinal Chemistry Letters. 3:557-560

مصطلحات موضوعية: Angiotensin II receptor type 1, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Combinatorial chemistry, Angiotensin II, Losartan, Drug Discovery, medicine, Molecular Medicine, heterocyclic compounds, Molecular Biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c3217cac370f56951dc027b462ec5425
https://doi.org/10.1016/s0960-894x(01)81228-2

المؤلفون: Robert A. Strelitz, W.J. Greenlee, Arthur A. Patchett, Gloria J. Zingaro, Terry W. Schorn, Peter K. S. Siegl, Salah D. Kivlighn, Tsing-Bau Chen, Victor J. Lotti, Prasun K. Chakravarty, Raymond S.L. Chang

المصدر: ChemInform. 25

مصطلحات موضوعية: Biphenyl, chemistry.chemical_compound, Angiotensin receptor, chemistry, Stereochemistry, General Medicine, Quinazolinone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6941a5642b96eab67db3e8e02b4d7ed9
https://doi.org/10.1002/chin.199426194

المؤلفون: Tsing-Bau Chen, Victor J. Lotti, W.J. Greenlee, Gloria J. Zingaro, R. S. L. Chang, Peter K. S. Siegl, Scott W. Bagley, Daljit S. Dhanoa, Prasun K. Chakravarty, Salah D. Kivlighn, Arthur A. Patchett

المصدر: ChemInform. 25

مصطلحات موضوعية: Angiotensin receptor, Chemistry, General Medicine, Pharmacology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::615d5394e4b6cf3e0fa7bbf73c8d8aa1
https://doi.org/10.1002/chin.199413190

المؤلفون: Catherine Abbadie, Brande S. Williams, Bindhu V. Karanam, Joseph L. Duffy, James B Herrington, Maria Madeira, Xiaohua Li, Vivien A. Warren, Michael J. Forrest, Andrew M. Swensen, Sriram Tyagarajan, Bishan Zhou, Prasun K. Chakravarty, Kathryn A. Lyons, Mitchell D. Green, Nina Jochnowitz, Kevin S. Ratliff, Erin McGowan, Owen B. McManus, Randall M. Bugianesi, McHardy M. Smith, Maria L. Garcia, Min Park, Gregory J. Kaczorowski, Shruti Mistry, Rodolfo Haedo

المصدر: Bioorganicmedicinal chemistry letters. 21(2)

مصطلحات موضوعية: Indoles, Stereochemistry, Clinical Biochemistry, Analgesic, Pharmaceutical Science, Pain, N-type calcium channel, Pharmacology, Biochemistry, Calcium Channels, N-Type, Dogs, In vivo, Drug Discovery, Potency, Animals, Humans, Molecular Biology, Indole test, Voltage-dependent calcium channel, Chemistry, Organic Chemistry, Antagonist, Haplorhini, Calcium Channel Blockers, In vitro, Rats, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f216a0cbc669778ea8da563217bc1cbf
https://pubmed.ncbi.nlm.nih.gov/21195616