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1Academic Journal
المصدر: JTCVS Open, Vol 14, Iss , Pp 87-88 (2023)
مصطلحات موضوعية: Diseases of the circulatory (Cardiovascular) system, RC666-701, Surgery, RD1-811
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Christopher J Arthurs, Rostislav Khlebnikov, Alex Melville, Marija Marčan, Alberto Gomez, Desmond Dillon-Murphy, Federica Cuomo, Miguel Silva Vieira, Jonas Schollenberger, Sabrina R Lynch, Christopher Tossas-Betancourt, Kritika Iyer, Sara Hopper, Elizabeth Livingston, Pouya Youssefi, Alia Noorani, Sabrina Ben Ahmed, Foeke J H Nauta, Theodorus M J van Bakel, Yunus Ahmed, Petrus A J van Bakel, Jonathan Mynard, Paolo Di Achille, Hamid Gharahi, Kevin D Lau, Vasilina Filonova, Miquel Aguirre, Nitesh Nama, Nan Xiao, Seungik Baek, Krishna Garikipati, Onkar Sahni, David Nordsletten, C Alberto Figueroa
المصدر: PLoS Computational Biology, Vol 17, Iss 5, p e1008881 (2021)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
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3
المؤلفون: Nathanael, Shraer, Pouya, Youssefi, Pavel, Zacek, Mathieu, Debauchez, Pascal, Leprince, Olivier, Raisky, Emmanuel, Lansac
المصدر: The Journal of Thoracic and Cardiovascular Surgery.
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Surgery, Cardiology and Cardiovascular Medicine
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4
المؤلفون: Nathanael Shraer, Pouya Youssefi, Jean-Luc Monin, Alain Berrebi, Leila Mankoubi, Milena Noghin, Mathieu Debauchez, Emmanuel Lansac
المصدر: European Journal of Cardio-Thoracic Surgery. 62
مصطلحات موضوعية: Reoperation, Pulmonary and Respiratory Medicine, Treatment Outcome, Aortic Valve, Aortic Valve Insufficiency, Humans, Surgery, General Medicine, Cardiology and Cardiovascular Medicine, Cardiac Valve Annuloplasty, Respect
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5
المؤلفون: Emmanuel Lansac, Pouya Youssefi
المصدر: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 60(4)
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.medical_specialty, Repair time, business.industry, Standardized approach, Aortic Valve Insufficiency, General Medicine, Cardiac Valve Annuloplasty, Surgery, Aortic valve repair, Bicuspid valve, Medicine, Humans, Mitral Valve, Cardiology and Cardiovascular Medicine, business
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6
المؤلفون: Pouya, Youssefi, Carlotta, Brega, Nathanael, Shraer, Pavel, Zacek, Mathieu, Debauchez, Emmanuel, Lansac
المصدر: The Annals of Thoracic Surgery. 108:1596-1604
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Bicuspid Aortic Valve Disease, Education, Medical, Graduate, Aortic Valve, Suture Techniques, Cardiology, Heart Valve Diseases, Humans, Aorta, Thoracic, Surgery, Cardiology and Cardiovascular Medicine, Cardiac Valve Annuloplasty
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7
المؤلفون: Mathieu Debauchez, Emmanuel Lansac, Pouya Youssefi, Pavel Zacek
المصدر: The Annals of Thoracic Surgery. 108:324-333
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Valve-sparing aortic root replacement, medicine.medical_specialty, business.industry, Heart Valve Diseases, Thoracic Surgery, Cardiac Valve Annuloplasty, Surgery, Lesion, Bicuspid Aortic Valve Disease, Education, Medical, Graduate, Bicuspid valve, Aortic Valve, Aortic valve surgery, medicine, Humans, Organ Sparing Treatments, medicine.symptom, Cardiology and Cardiovascular Medicine, business
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8
المؤلفون: C. Alberto Figueroa, Robert Wright, Alberto Gomez, Marjan Jahangiri, Pouya Youssefi, Marija Marčan, Christopher J. Arthurs
المصدر: Gomez, A, Marcan, M, Arthurs, C, Wright, R, Youssefi, P, Jahangiri, M & Figueroa, A 2019, ' Optimal B-spline Mapping of Flow Imaging Data for Imposing Patient-specific Velocity Profiles in Computational Hemodynamics ', IEEE Transactions on Biomedical Engineering, vol. 66, no. 7, pp. 1872-1883 . https://doi.org/10.1109/TBME.2018.2880606
IEEE transactions on bio-medical engineeringمصطلحات موضوعية: Computer science, Physics::Medical Physics, 0206 medical engineering, Biomedical Engineering, Hemodynamics, 02 engineering and technology, Computational fluid dynamics, computer.software_genre, Article, Magnetic resonance imaging, Bicuspid aortic valve, medicine, Doppler Ultrasound, Patient-specific Modelling, Pointwise, Tricuspid valve, business.industry, B-spline, Data models, Computational modeling, Blood flow, medicine.disease, Magnetic Resonance Imaging, Doppler effect, Valves, 020601 biomedical engineering, Volumetric flow rate, Simulation software, Blood, medicine.anatomical_structure, Flow (mathematics), Flow Profile, Three-dimensional displays, CFD, business, Geometric modeling, computer, Algorithm
وصف الملف: application/pdf
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9
المؤلفون: Emmanuel Lansac, Hou-Sen Lim, Yu Shomura, Isabelle Di Centa, Nolan T. Rice, Wolfgang A. Goetz, Pouya Youssefi, Carlos M.G. Duran, Khee Hiang Lim
المصدر: Annals of Cardiothoracic Surgery. 8:351-361
مصطلحات موضوعية: Aortic valve, medicine.medical_specialty, Contraction (grammar), business.industry, Sinotubular Junction, Featured Article, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Aortic valve repair, medicine.anatomical_structure, 030228 respiratory system, Internal medicine, medicine.artery, Ascending aorta, cardiovascular system, medicine, Cardiology, Surgery, Systole, Cardiology and Cardiovascular Medicine, business, Isovolumetric contraction, Body orifice
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10
المؤلفون: Pouya Youssefi, Mustafa Zakkar, Christophe Acar, Emmanuel Lansac, Nizar Khelil, Mathieu Debauchez
المصدر: Annals of Cardiothoracic Surgery. 8:401-410
مصطلحات موضوعية: medicine.medical_specialty, Aorta, business.industry, Art of Operative Techniques, Sinotubular Junction, Ring annuloplasty, medicine.disease, Congenital cardiovascular anomaly, Bicuspid aortic valve, Bicuspid valve, medicine.artery, Internal medicine, Ascending aorta, cardiovascular system, medicine, Cardiology, Surgery, Cardiology and Cardiovascular Medicine, business, Dilated aortic root
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11
المؤلفون: Mustafa Zakkar, Isabelle Di Centa, Emmanuel Lansac, Mathieu Debauchez, Nizar Khelil, Pouya Youssefi
المصدر: Annals of Cardiothoracic Surgery. 8:418-421
مصطلحات موضوعية: Aortic valve, medicine.medical_specialty, business.industry, Masters of Cardiothoracic Surgery, Ring annuloplasty, Sinotubular Junction, Long term results, 030204 cardiovascular system & hematology, Surgery, 03 medical and health sciences, 0302 clinical medicine, Aortic valve repair, medicine.anatomical_structure, 030228 respiratory system, cardiovascular system, medicine, cardiovascular diseases, Cardiology and Cardiovascular Medicine, business
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12
المؤلفون: Daniel Czytrom, Leila Mankoubi, Alain Berrebi, Milena Noghin, Pavel Zacek, Emmanuel Lansac, Mathieu Debauchez, Jean Luc Monin, Pouya Youssefi
المصدر: The Journal of cardiovascular surgery. 62(1)
مصطلحات موضوعية: medicine.medical_specialty, Aortic Valve Insufficiency, Hemodynamics, 030204 cardiovascular system & hematology, Cardiac Valve Annuloplasty, 03 medical and health sciences, 0302 clinical medicine, Aortic valve repair, Aortic ring, Risk Factors, medicine.artery, Internal medicine, Ascending aorta, medicine, Humans, Cardiac skeleton, Prosthetic valve, Heart Valve Prosthesis Implantation, Aorta, business.industry, Sinotubular Junction, General Medicine, Recovery of Function, Aortic Aneurysm, Treatment Outcome, 030228 respiratory system, Aortic Valve, Heart Valve Prosthesis, cardiovascular system, Cardiology, Quality of Life, Surgery, Cardiology and Cardiovascular Medicine, business
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المؤلفون: Pouya Youssefi, Emmanuel Lansac
المصدر: Indian J Thorac Cardiovasc Surg
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Aortic valve, medicine.medical_specialty, business.industry, Sinotubular Junction, Review Article, 030204 cardiovascular system & hematology, medicine.disease, Surgery, Cardiac surgery, 03 medical and health sciences, 0302 clinical medicine, Aortic valve repair, Aneurysm, medicine.anatomical_structure, 030228 respiratory system, Cardiothoracic surgery, medicine.artery, Ascending aorta, medicine, cardiovascular system, Cardiac skeleton, Cardiology and Cardiovascular Medicine, business
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14
المؤلفون: Miguel Silva Vieira, Alberto Gomez, Rostislav Khlebnikov, Alex Melville, Christopher Tossas-Betancourt, Christopher J. Arthurs, Sara E Hopper, Pouya Youssefi, Seungik Baek, C. Alberto Figueroa, Marija Marčan, Jonathan Mynard, Vasilina Filonova, Paolo Di Achille, Jonas Schollenberger, Onkar Sahni, David Nordsletten, Miquel Aguirre, Elizabeth Renee Livingston, Sabrina Ben Ahmed, Alia Noorani, Federica Cuomo, Sabrina R. Lynch, Yunus Ahmed, Nitesh Nama, Krishna Garikipati, KD Lau, Theodorus M. J. van Bakel, Hamid Gharahi, Desmond Dillon-Murphy, Kritika Iyer, Petrus A. J. van Bakel, Foeke J. H. Nauta, Nan Xiao
المصدر: PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 5, p e1008881 (2021)مصطلحات موضوعية: Man-Computer Interface, Models, Anatomic, Patient-Specific Modeling, Source code, Physiology, Computer science, Blood Pressure, 02 engineering and technology, 030204 cardiovascular system & hematology, Vascular Medicine, Computer Applications, Computer Architecture, User-Computer Interface, Electronics Engineering, Open Science, Postoperative Complications, 0302 clinical medicine, Documentation, Software, Blood Flow, Medicine and Health Sciences, Computer Engineering, Graphical User Interfaces, Biology (General), Graphical user interface, media_common, Ecology, Simulation and Modeling, Applied Mathematics, Models, Cardiovascular, Software Engineering, Hematology, Magnetic Resonance Imaging, Finite element method, Body Fluids, Alagille Syndrome, Blood, Computational Theory and Mathematics, Mesh generation, Modeling and Simulation, Physical Sciences, Engineering and Technology, Anatomy, Open Source Software, Research Article, Computer and Information Sciences, QH301-705.5, Science Policy, Computation, media_common.quotation_subject, Finite Element Analysis, 0206 medical engineering, Image processing, Research and Analysis Methods, Computer Software, Cellular and Molecular Neuroscience, 03 medical and health sciences, Imaging, Three-Dimensional, Genetics, Humans, Leverage (statistics), Computer Simulation, Molecular Biology, Computerized Simulations, Ecology, Evolution, Behavior and Systematics, business.industry, Hemodynamics, Biology and Life Sciences, Computational Biology, Pipeline (software), 020601 biomedical engineering, Liver Transplantation, Heart Disease Risk Factors, Microsoft Windows, Blood Vessels, Software engineering, business, Mathematics, User Interfaces
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15
المؤلفون: Jean-François Fuzellier, Christophe de Meester, Rémi Houel, Florence Tubach, Georges Fayad, Maciej Matuszewski, Eric Arnaud-Crozat, Svenja Rauch, Jean-François Obadia, Adrian Kolesar, Matteo Pettinari, Bardia Arabkhani, Jos A. Bekkers, Fabrizio Ceresa, Andrea Mangini, Dave R. Koolbergen, Daniel Czytrom, František Sabol, Thomas J van Brakel, Ignacio Bibiloni, Pallav Shah, Rosina Ziller, Alain Leguerrier, Marek Jasiński, Gianclaudio Mecozzi, Mihail Svetkin, Taoufik Benkacem, Jaroslav Hlubocky, Hans-Joachim Schäfers, Vincent Doisy, Jean-Luc Monin, Christine Leon, Carlo Antona, Jan Vojacek, Munir Boodhwani, Francesco Patane, Andrey Slautin, Gebrine Elkhoury, Rubina Rosa, Yutaka Okita, Ismail El-Hamamsy, Wenke Goossens, Alain Berrebi, Paolo Ferrero, Jan Nijs, Fabien Doguet, Mauro Masat, Monica Contino, Edward P. Chen, Gregorio Rábago, Stéphane Lopez, Duke E. Cameron, Johannes Steindl, José Aramendi, Eric Bergoend, Maurice Enriquez-Sarano, Jean-Louis Vanoverschelde, Bart Meuris, Virginia Alvarez-Asiain, Robert Novotny, Davor Barić, Michael A. Borger, Tomas Toporcer, Ruggero De Paulis, Leila Mankoubi, J. M. Marnette, Christelle Diakov, Amaia Melero, Said Soliman, Michael Tousch, Ryan E. Accord, Philippe Pibarot, Mikita Karalko, Vladislav Aminov, Agnes Pasquet, Serban Stoica, David Messika Zeitoun, Olivier Bouchot, Bernard Albat, Jérôme Jouan, Savica Gjorgijevska, Klaartje Van den Bossche, Igor Rudez, J. Kluin, Laurent de Guillaume Jondeau, Didier Chatel, Pascal Leprince, Sarah Pousset, Rafael Sadaba, Veerle Van Mossevelde, Evi Schepmans, Johanna J.M. Takkenberg, Carlos Porras, Herbert Gutermann, Isabelle Di Centa, Aude Boignard, Joseph E. Bavaria, Pierre-Emmanuel Noly, Yves Glock, Corinne Coulon, Bart Loeys, Rita K. Milewski, Christian Dinges, Marien Lenoir, Francesco Grigioni, Alejandro Crespo, Patrick Moeller, Frederiek de Heer, Mohamad Bashir, Milean Noghin, Fadoua Kaddouri, Takashi Kunihara, Isaac Wenger, Ilaria Chirichilli, Claudia Romagnoni, Diana Aicher, Arturo Evangelista Masip, Daniel Unić, Emmanuel Lansac, Fabrice Wautot, Peter Verbrugghe, Laurent de Kerchove, Pouya Youssefi, Josip Varvodić, Robert J.M. Klautz, Patrick Yiu, Frank Theisohn, Pavel Zacek, Guy Fernandez, Takeshi Miyairi, Thierry Bourguignon
المساهمون: Cardiothoracic Surgery, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Service de pathologie cardiovasculaire, UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique
المصدر: Seminars in Thoracic and Cardiovascular Surgery, 31(4), 643-649. W.B. Saunders
Seminars in thoracic and cardiovascular surgery, Vol. 31, no.4, p. 643-649 (2021)مصطلحات موضوعية: Aortic valve, Time Factors, Nonelderly patients, medicine.medical_treatment, Heart Valve Diseases, AVIATOR, Aortic valve surgery, Adult, Age Factors, Aortic Valve, Bioprosthesis, Evidence-Based Medicine, Heart Valve Prosthesis, Life Expectancy, Middle Aged, Prosthesis Failure, Recovery of Function, Registries, Risk Factors, Treatment Outcome, Heart Valve Prosthesis Implantation, Transcatheter Aortic Valve Replacement, 030204 cardiovascular system & hematology, 0302 clinical medicine, Aortic valve repair, Quality of life, Expectancy theory, education.field_of_study, Ross procedure, General Medicine, medicine.anatomical_structure, Cardiology and Cardiovascular Medicine, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Population, 03 medical and health sciences, medicine, Humans, education, business.industry, Mechanical Aortic Valve, Surgery, Settore MED/23, 030228 respiratory system, Life expectancy, business
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16
المؤلفون: Rajan Sharma, Bernard Liban, Gopal Soppa, Justin Nowell, Maite Tome, Pouya Youssefi, Marjan Jahangiri, Mark Edsell, Anne H. Child, Rajdeep Bilkhu, Panagiotis Theodoropoulos, Simon Phillips
المصدر: The Annals of Thoracic Surgery. 106:771-776
مصطلحات موضوعية: Male, Aortic arch, Heart Valve Diseases, Aorta, Thoracic, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, Cohort Studies, Postoperative Complications, 0302 clinical medicine, Bicuspid aortic valve, Bicuspid Aortic Valve Disease, Hospital Mortality, 030212 general & internal medicine, Heart Valve Prosthesis Implantation, education.field_of_study, Anastomosis, Surgical, Middle Aged, Prognosis, Aortic Aneurysm, Survival Rate, Treatment Outcome, Elective Surgical Procedures, Cardiothoracic surgery, Aortic Valve, cardiovascular system, Female, Cardiology and Cardiovascular Medicine, Reoperation, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Population, Dissection (medical), Risk Assessment, 03 medical and health sciences, Aneurysm, medicine.artery, Ascending aorta, medicine, Humans, education, Aged, Proportional Hazards Models, Retrospective Studies, Aorta, business.industry, Length of Stay, medicine.disease, United Kingdom, Surgery, Aortic Dissection, Emergencies, business
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17Image
المؤلفون: Christopher J. Arthurs (10777046), Rostislav Khlebnikov (10777049), Alex Melville (10777052), Marija Marčan (735057), Alberto Gomez (3321279), Desmond Dillon-Murphy (3808777), Federica Cuomo (3808774), Miguel Silva Vieira (5946020), Jonas Schollenberger (10777055), Sabrina R. Lynch (10777058), Christopher Tossas-Betancourt (8380233), Kritika Iyer (10777061), Sara Hopper (10777064), Elizabeth Livingston (10777067), Pouya Youssefi (6838020), Alia Noorani (10777070), Sabrina Ben Ahmed (10777073), Foeke J. H. Nauta (2656975), Theodorus M. J. van Bakel (4495753), Yunus Ahmed (10777076), Petrus A. J. van Bakel (10777079), Jonathan Mynard (10777082), Paolo Di Achille (5627609), Hamid Gharahi (10777085), Kevin D. Lau (10777088), Vasilina Filonova (10777091), Miquel Aguirre (10777094), Nitesh Nama (1319637), Nan Xiao (406004), Seungik Baek (2280766), Krishna Garikipati (243585), Onkar Sahni (10777097), David Nordsletten (6084620), C. Alberto Figueroa (3808780)
مصطلحات موضوعية: Medicine, Biotechnology, Science Policy, Space Science, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, incompressible Navier-Stokes simula., wall shear stress fields, haemodynamic, element mesh generation, open-source software framework, image, modelling, problem, fluid-structure interaction capabil., software environment, CRIMSON, CardiovasculaR Integrated Modelling, flow, device design optimization
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18Image
المؤلفون: Christopher J. Arthurs (10777046), Rostislav Khlebnikov (10777049), Alex Melville (10777052), Marija Marčan (735057), Alberto Gomez (3321279), Desmond Dillon-Murphy (3808777), Federica Cuomo (3808774), Miguel Silva Vieira (5946020), Jonas Schollenberger (10777055), Sabrina R. Lynch (10777058), Christopher Tossas-Betancourt (8380233), Kritika Iyer (10777061), Sara Hopper (10777064), Elizabeth Livingston (10777067), Pouya Youssefi (6838020), Alia Noorani (10777070), Sabrina Ben Ahmed (10777073), Foeke J. H. Nauta (2656975), Theodorus M. J. van Bakel (4495753), Yunus Ahmed (10777076), Petrus A. J. van Bakel (10777079), Jonathan Mynard (10777082), Paolo Di Achille (5627609), Hamid Gharahi (10777085), Kevin D. Lau (10777088), Vasilina Filonova (10777091), Miquel Aguirre (10777094), Nitesh Nama (1319637), Nan Xiao (406004), Seungik Baek (2280766), Krishna Garikipati (243585), Onkar Sahni (10777097), David Nordsletten (6084620), C. Alberto Figueroa (3808780)
مصطلحات موضوعية: Medicine, Biotechnology, Science Policy, Space Science, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, incompressible Navier-Stokes simula., wall shear stress fields, haemodynamic, element mesh generation, open-source software framework, image, modelling, problem, fluid-structure interaction capabil., software environment, CRIMSON, CardiovasculaR Integrated Modelling, flow, device design optimization
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19Image
المؤلفون: Christopher J. Arthurs (10777046), Rostislav Khlebnikov (10777049), Alex Melville (10777052), Marija Marčan (735057), Alberto Gomez (3321279), Desmond Dillon-Murphy (3808777), Federica Cuomo (3808774), Miguel Silva Vieira (5946020), Jonas Schollenberger (10777055), Sabrina R. Lynch (10777058), Christopher Tossas-Betancourt (8380233), Kritika Iyer (10777061), Sara Hopper (10777064), Elizabeth Livingston (10777067), Pouya Youssefi (6838020), Alia Noorani (10777070), Sabrina Ben Ahmed (10777073), Foeke J. H. Nauta (2656975), Theodorus M. J. van Bakel (4495753), Yunus Ahmed (10777076), Petrus A. J. van Bakel (10777079), Jonathan Mynard (10777082), Paolo Di Achille (5627609), Hamid Gharahi (10777085), Kevin D. Lau (10777088), Vasilina Filonova (10777091), Miquel Aguirre (10777094), Nitesh Nama (1319637), Nan Xiao (406004), Seungik Baek (2280766), Krishna Garikipati (243585), Onkar Sahni (10777097), David Nordsletten (6084620), C. Alberto Figueroa (3808780)
مصطلحات موضوعية: Medicine, Biotechnology, Science Policy, Space Science, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, incompressible Navier-Stokes simula., wall shear stress fields, haemodynamic, element mesh generation, open-source software framework, image, modelling, problem, fluid-structure interaction capabil., software environment, CRIMSON, CardiovasculaR Integrated Modelling, flow, device design optimization
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20Image
المؤلفون: Christopher J. Arthurs (10777046), Rostislav Khlebnikov (10777049), Alex Melville (10777052), Marija Marčan (735057), Alberto Gomez (3321279), Desmond Dillon-Murphy (3808777), Federica Cuomo (3808774), Miguel Silva Vieira (5946020), Jonas Schollenberger (10777055), Sabrina R. Lynch (10777058), Christopher Tossas-Betancourt (8380233), Kritika Iyer (10777061), Sara Hopper (10777064), Elizabeth Livingston (10777067), Pouya Youssefi (6838020), Alia Noorani (10777070), Sabrina Ben Ahmed (10777073), Foeke J. H. Nauta (2656975), Theodorus M. J. van Bakel (4495753), Yunus Ahmed (10777076), Petrus A. J. van Bakel (10777079), Jonathan Mynard (10777082), Paolo Di Achille (5627609), Hamid Gharahi (10777085), Kevin D. Lau (10777088), Vasilina Filonova (10777091), Miquel Aguirre (10777094), Nitesh Nama (1319637), Nan Xiao (406004), Seungik Baek (2280766), Krishna Garikipati (243585), Onkar Sahni (10777097), David Nordsletten (6084620), C. Alberto Figueroa (3808780)
مصطلحات موضوعية: Medicine, Biotechnology, Science Policy, Space Science, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, incompressible Navier-Stokes simula., wall shear stress fields, haemodynamic, element mesh generation, open-source software framework, image, modelling, problem, fluid-structure interaction capabil., software environment, CRIMSON, CardiovasculaR Integrated Modelling, flow, device design optimization